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The map label for this gene is vanX [H]

Identifier: 189353209

GI number: 189353209

Start: 1436972

End: 1437535

Strand: Direct

Name: vanX [H]

Synonym: BMULJ_04445

Alternate gene names: 189353209

Gene position: 1436972-1437535 (Clockwise)

Preceding gene: 189353208

Following gene: 189353210

Centisome position: 58.1

GC content: 70.92

Gene sequence:

>564_bases
ATGAACGATCACCGCCTCGTCGAAATCACGCCCGCCACGCATCGCGTCGAGATCGACCTCGTCTATGCGACCGAGCGCAA
CCTGACCGGCAAGCCGATCTACCGCCGCGCGCACTGCCTGTTGCTCGCGCCGGCCGAAGCGGCGCTGCGCCGCGCGGTGG
ACGTCGCCGCGCAGGCCGGCTTCACGCTGCGCATCTACGACGCATACCGGCCGCCGGAGGCGCAGCAGGTGCTGTGGGAT
TTCCTGCCGGACCCGAACTTCGTCGCCGATCTCGGCCGCGGCTCGAATCACAGCCGCGGCACGGCGCTCGACCTGACGCT
CGTCGGCGCCGACGGCGAGCCGCTCGACATGGGCACCGGCTTCGACGAGATGGTGGCCGCCTCCGGGCACTTCCACGCGG
GGCTGTCCGAGGCCGTGCAGCGCAACCGGCTGCTGCTGCTCGGCGTGATGCACGCGGCCGGCTTCGCGCATATCGACAGC
GAATGGTGGCACTACGAGCTGCCCGGCTCGCGCGCGCTGCCGGTGATCGACAACGACGCCAGCGGCCCGTGGCGCCTGAT
GTGA

Upstream 100 bases:

>100_bases
GTCGACCGTCTCGGCCCCGCCATCGACCGGCGCGTCGCGCGCAACCGCGAATTGCAGCGCACCTTCGATCAATTCGAATC
CTGAGAGAACCCATTTGCCG

Downstream 100 bases:

>100_bases
CGCACGTCCCCCTTTCCGTTCACGTTCAACGACATCAACGACAGATGGAGCGCCCATGAAACCCCTGACATCCCGGCTCG
TCGCCGCCGCCGTGCTCGCC

Product: D-alanyl-D-alanine dipeptidase

Products: NA

Alternate protein names: D-Ala-D-Ala dipeptidase [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MNDHRLVEITPATHRVEIDLVYATERNLTGKPIYRRAHCLLLAPAEAALRRAVDVAAQAGFTLRIYDAYRPPEAQQVLWD
FLPDPNFVADLGRGSNHSRGTALDLTLVGADGEPLDMGTGFDEMVAASGHFHAGLSEAVQRNRLLLLGVMHAAGFAHIDS
EWWHYELPGSRALPVIDNDASGPWRLM

Sequences:

>Translated_187_residues
MNDHRLVEITPATHRVEIDLVYATERNLTGKPIYRRAHCLLLAPAEAALRRAVDVAAQAGFTLRIYDAYRPPEAQQVLWD
FLPDPNFVADLGRGSNHSRGTALDLTLVGADGEPLDMGTGFDEMVAASGHFHAGLSEAVQRNRLLLLGVMHAAGFAHIDS
EWWHYELPGSRALPVIDNDASGPWRLM
>Mature_187_residues
MNDHRLVEITPATHRVEIDLVYATERNLTGKPIYRRAHCLLLAPAEAALRRAVDVAAQAGFTLRIYDAYRPPEAQQVLWD
FLPDPNFVADLGRGSNHSRGTALDLTLVGADGEPLDMGTGFDEMVAASGHFHAGLSEAVQRNRLLLLGVMHAAGFAHIDS
EWWHYELPGSRALPVIDNDASGPWRLM

Specific function: Hydrolyzes D-Ala-D-Ala. May have a role in cell-wall turnover [H]

COG id: COG2173

COG function: function code M; D-alanyl-D-alanine dipeptidase

Gene ontology:

Cell location: Secreted (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M15D family [H]

Homologues:

Organism=Escherichia coli, GI1787763, Length=177, Percent_Identity=48.5875706214689, Blast_Score=172, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009045
- InterPro:   IPR000755 [H]

Pfam domain/function: PF01427 Peptidase_M15 [H]

EC number: =3.4.13.22 [H]

Molecular weight: Translated: 20617; Mature: 20617

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDHRLVEITPATHRVEIDLVYATERNLTGKPIYRRAHCLLLAPAEAALRRAVDVAAQAG
CCCCEEEEECCCCEEEEEEEEEEECCCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHCC
FTLRIYDAYRPPEAQQVLWDFLPDPNFVADLGRGSNHSRGTALDLTLVGADGEPLDMGTG
CEEEEEECCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCC
FDEMVAASGHFHAGLSEAVQRNRLLLLGVMHAAGFAHIDSEWWHYELPGSRALPVIDNDA
HHHHHHCCCCCCCCHHHHHHHCCEEEEEEEHHCCEEEECCCCEEEECCCCCCCCEEECCC
SGPWRLM
CCCEECC
>Mature Secondary Structure
MNDHRLVEITPATHRVEIDLVYATERNLTGKPIYRRAHCLLLAPAEAALRRAVDVAAQAG
CCCCEEEEECCCCEEEEEEEEEEECCCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHCC
FTLRIYDAYRPPEAQQVLWDFLPDPNFVADLGRGSNHSRGTALDLTLVGADGEPLDMGTG
CEEEEEECCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCC
FDEMVAASGHFHAGLSEAVQRNRLLLLGVMHAAGFAHIDSEWWHYELPGSRALPVIDNDA
HHHHHHCCCCCCCCHHHHHHHCCEEEEEEEHHCCEEEECCCCEEEECCCCCCCCEEECCC
SGPWRLM
CCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]