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The map label for this gene is 189353188

Identifier: 189353188

GI number: 189353188

Start: 1412963

End: 1414612

Strand: Direct

Name: 189353188

Synonym: BMULJ_04424

Alternate gene names: NA

Gene position: 1412963-1414612 (Clockwise)

Preceding gene: 189353182

Following gene: 189353189

Centisome position: 57.13

GC content: 71.88

Gene sequence:

>1650_bases
ATGAGCGCCAAACGTCTCAACCTTGCCGTGGCACGCGCAGGCCACGCGCGCATGCTCGCCGGCATCCTGTCGGCCGCCGC
CCTCCTTCCTCTCGCGGGCTGCGGCGGAGGCGGCGGCGACGGCGGCACGACGCCGCCGTCGAACGCGTCGCCGGCACCGA
CGCCGACGCCCGCGCCCACGCCGGCCCCGAGCGCGCCGCCGGCCTCGTCGAGCAATGGCGCGTGCACGACCTCGCAAGCC
GCCGCGCAGATGGCCGCTCAGAGCGTCGCGCCGACCGAACCGCCGGTCGATCATCTGATCGTTCGGCTGAAAACGTCGAC
CGCCACGCATGCGATGGCCGCCTCCGATACCGCATCGCGCTTCGACGCCGTGATCCAGCGCTCGATCGCACGCTGGAACG
CGCCGGTCGGCACCGCCCGCGCCTATGCGAGCGCCGCCGCGCAGACGTCGCTGAACGTGCAGGTCGAGCGCACGATCTCG
AACGGCGCGGCCGTGCTCGCGCTCGGCCAGCGGATCGCCGCGGCCGACGCCGACGCGCTCGCGCAGGCGTTCGCGGCCGA
TGCCGACGTCGACTACGCGGAACCCGATCACCGGATGAACGTGCGCGACACGCCGACCGACCCCGACTACAACCAGCAGT
GGTATCTGTTCGATCAGACCGGCGGCGTCGATCTGCCGGCCGCCTGGGATCGCACGAAGGGCTCGCCGAGCGTCGTCACG
GCCGTGCTCGACACCGGCTATCGGCCGCACGAGGATCTCAACGCGAACCTGCTGCCCGGCTACAGCTTCATCTCCGACAT
CAACGTCAGCAACAACGGCAAGACGCGCGGCAGCGACGCGACCGATCCGGGCGACTGGGTCACGCAGCAGGAACTCGACG
ATCCGAACGGCCCGTACTACCACTGCGAAAGCCAGCCGAGCAACAGCACGTGGCACGGCACGCGCGTGATGGGCGTGATC
GGCGCGAACGCGAACAACGGCAAGGGCATCGCCGGCGTGTCGTGGCTCGGCCGCATCCTGCCCGTGCGCGTGCTCGGCAA
ATGCGGCGGCTCGACGAGCGACATCGCGGACGCGATGCGCTGGGCGGCCGGCATCCCCGTGAACGGCGCGCCGAACAATC
CGACGCCCGCGAAGGTGATCAACCTGAGCCTCGGCGGCAGCGGCGCCTGCAGCACGACGTTCCAGCAGGCGATCGACGAC
GTGACGGCGAAGGGCGTGACCGTCGTCGTCGCGGCCGGCAACGACGGGCAGTCGACCGCGCTCGATCAGCCCGCGAACTG
CCGCGGCGTGATCGCGGTCGGCGCGACCGATTCGACCGGCCGCCGCGCGTCGTTCAGCAACTTCGGCTCCGACGTCGCAC
TGAGCGCACCGGGTGTCGGCATCGTGTCGACCGCGAATTCGGGCACGACGACGCCGGGCACCGACACGTACGGCCCCGCG
AACGGCACGAGCTTCGCCGCGCCGCAGGTGAGCGGCGTCGCCGCGCTGATGCTGTCGATAAACGGCAACCTGACGCCCGC
GCAGATCCAGCAGAAGCTGCAAGGCGGCACGCGCGCGGCAAAGCTCGCGGCCGGCACGTCGTGCACGGCGGCGCCGGCCG
GTTCGGGCATCCTCGACGCCGGCGCGGCCGTCGCTTCCGCGGCCCCGTGA

Upstream 100 bases:

>100_bases
CACGCGGCATCCGGCCGCCGCGCCCGCAGCAACGGGTCGGCACGGCCGGCCCGGGTTCCACGCCGGCACGACGGCTTCCT
AACGAGGATCGAGTTTCAAC

Downstream 100 bases:

>100_bases
TGCACGTTACGCAGCCGCGCACGCATCGGCGTCGCGCGGCTGCGTGGCGACGCCGAGCCCGCTGCGATGCTTCAAGCGAT
CGGCAAAAAGGGTTGACGCT

Product: subtilisin-like serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MSAKRLNLAVARAGHARMLAGILSAAALLPLAGCGGGGGDGGTTPPSNASPAPTPTPAPTPAPSAPPASSSNGACTTSQA
AAQMAAQSVAPTEPPVDHLIVRLKTSTATHAMAASDTASRFDAVIQRSIARWNAPVGTARAYASAAAQTSLNVQVERTIS
NGAAVLALGQRIAAADADALAQAFAADADVDYAEPDHRMNVRDTPTDPDYNQQWYLFDQTGGVDLPAAWDRTKGSPSVVT
AVLDTGYRPHEDLNANLLPGYSFISDINVSNNGKTRGSDATDPGDWVTQQELDDPNGPYYHCESQPSNSTWHGTRVMGVI
GANANNGKGIAGVSWLGRILPVRVLGKCGGSTSDIADAMRWAAGIPVNGAPNNPTPAKVINLSLGGSGACSTTFQQAIDD
VTAKGVTVVVAAGNDGQSTALDQPANCRGVIAVGATDSTGRRASFSNFGSDVALSAPGVGIVSTANSGTTTPGTDTYGPA
NGTSFAAPQVSGVAALMLSINGNLTPAQIQQKLQGGTRAAKLAAGTSCTAAPAGSGILDAGAAVASAAP

Sequences:

>Translated_549_residues
MSAKRLNLAVARAGHARMLAGILSAAALLPLAGCGGGGGDGGTTPPSNASPAPTPTPAPTPAPSAPPASSSNGACTTSQA
AAQMAAQSVAPTEPPVDHLIVRLKTSTATHAMAASDTASRFDAVIQRSIARWNAPVGTARAYASAAAQTSLNVQVERTIS
NGAAVLALGQRIAAADADALAQAFAADADVDYAEPDHRMNVRDTPTDPDYNQQWYLFDQTGGVDLPAAWDRTKGSPSVVT
AVLDTGYRPHEDLNANLLPGYSFISDINVSNNGKTRGSDATDPGDWVTQQELDDPNGPYYHCESQPSNSTWHGTRVMGVI
GANANNGKGIAGVSWLGRILPVRVLGKCGGSTSDIADAMRWAAGIPVNGAPNNPTPAKVINLSLGGSGACSTTFQQAIDD
VTAKGVTVVVAAGNDGQSTALDQPANCRGVIAVGATDSTGRRASFSNFGSDVALSAPGVGIVSTANSGTTTPGTDTYGPA
NGTSFAAPQVSGVAALMLSINGNLTPAQIQQKLQGGTRAAKLAAGTSCTAAPAGSGILDAGAAVASAAP
>Mature_548_residues
SAKRLNLAVARAGHARMLAGILSAAALLPLAGCGGGGGDGGTTPPSNASPAPTPTPAPTPAPSAPPASSSNGACTTSQAA
AQMAAQSVAPTEPPVDHLIVRLKTSTATHAMAASDTASRFDAVIQRSIARWNAPVGTARAYASAAAQTSLNVQVERTISN
GAAVLALGQRIAAADADALAQAFAADADVDYAEPDHRMNVRDTPTDPDYNQQWYLFDQTGGVDLPAAWDRTKGSPSVVTA
VLDTGYRPHEDLNANLLPGYSFISDINVSNNGKTRGSDATDPGDWVTQQELDDPNGPYYHCESQPSNSTWHGTRVMGVIG
ANANNGKGIAGVSWLGRILPVRVLGKCGGSTSDIADAMRWAAGIPVNGAPNNPTPAKVINLSLGGSGACSTTFQQAIDDV
TAKGVTVVVAAGNDGQSTALDQPANCRGVIAVGATDSTGRRASFSNFGSDVALSAPGVGIVSTANSGTTTPGTDTYGPAN
GTSFAAPQVSGVAALMLSINGNLTPAQIQQKLQGGTRAAKLAAGTSCTAAPAGSGILDAGAAVASAAP

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI4505579, Length=376, Percent_Identity=28.7234042553192, Blast_Score=76, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6324576, Length=192, Percent_Identity=31.7708333333333, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320775, Length=217, Percent_Identity=30.8755760368664, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319893, Length=206, Percent_Identity=32.0388349514563, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007280
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8; PF04151 PPC [H]

EC number: NA

Molecular weight: Translated: 54984; Mature: 54853

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKRLNLAVARAGHARMLAGILSAAALLPLAGCGGGGGDGGTTPPSNASPAPTPTPAPT
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PAPSAPPASSSNGACTTSQAAAQMAAQSVAPTEPPVDHLIVRLKTSTATHAMAASDTASR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHCCHHHH
FDAVIQRSIARWNAPVGTARAYASAAAQTSLNVQVERTISNGAAVLALGQRIAAADADAL
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCEEEEEEEEECCCCEEEEECCCHHHHCCHHHH
AQAFAADADVDYAEPDHRMNVRDTPTDPDYNQQWYLFDQTGGVDLPAAWDRTKGSPSVVT
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHEEH
AVLDTGYRPHEDLNANLLPGYSFISDINVSNNGKTRGSDATDPGDWVTQQELDDPNGPYY
HHHHCCCCCCCCCCCCCCCCCHHHEECCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEE
HCESQPSNSTWHGTRVMGVIGANANNGKGIAGVSWLGRILPVRVLGKCGGSTSDIADAMR
EECCCCCCCCCCCEEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
WAAGIPVNGAPNNPTPAKVINLSLGGSGACSTTFQQAIDDVTAKGVTVVVAAGNDGQSTA
HHCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCC
LDQPANCRGVIAVGATDSTGRRASFSNFGSDVALSAPGVGIVSTANSGTTTPGTDTYGPA
CCCCCCCCEEEEECCCCCCCCCCCHHHCCCCEEECCCCCEEEEECCCCCCCCCCCCCCCC
NGTSFAAPQVSGVAALMLSINGNLTPAQIQQKLQGGTRAAKLAAGTSCTAAPAGSGILDA
CCCCCCCCCHHCEEEEEEEECCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCHHC
GAAVASAAP
CHHHHCCCC
>Mature Secondary Structure 
SAKRLNLAVARAGHARMLAGILSAAALLPLAGCGGGGGDGGTTPPSNASPAPTPTPAPT
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PAPSAPPASSSNGACTTSQAAAQMAAQSVAPTEPPVDHLIVRLKTSTATHAMAASDTASR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHCCHHHH
FDAVIQRSIARWNAPVGTARAYASAAAQTSLNVQVERTISNGAAVLALGQRIAAADADAL
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCEEEEEEEEECCCCEEEEECCCHHHHCCHHHH
AQAFAADADVDYAEPDHRMNVRDTPTDPDYNQQWYLFDQTGGVDLPAAWDRTKGSPSVVT
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHEEH
AVLDTGYRPHEDLNANLLPGYSFISDINVSNNGKTRGSDATDPGDWVTQQELDDPNGPYY
HHHHCCCCCCCCCCCCCCCCCHHHEECCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEE
HCESQPSNSTWHGTRVMGVIGANANNGKGIAGVSWLGRILPVRVLGKCGGSTSDIADAMR
EECCCCCCCCCCCEEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
WAAGIPVNGAPNNPTPAKVINLSLGGSGACSTTFQQAIDDVTAKGVTVVVAAGNDGQSTA
HHCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCC
LDQPANCRGVIAVGATDSTGRRASFSNFGSDVALSAPGVGIVSTANSGTTTPGTDTYGPA
CCCCCCCCEEEEECCCCCCCCCCCHHHCCCCEEECCCCCEEEEECCCCCCCCCCCCCCCC
NGTSFAAPQVSGVAALMLSINGNLTPAQIQQKLQGGTRAAKLAAGTSCTAAPAGSGILDA
CCCCCCCCCHHCEEEEEEEECCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCHHC
GAAVASAAP
CHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2187155; 12024217 [H]