Click here to switch to the map view.

The map label for this gene is mocR [H]

Identifier: 189353133

GI number: 189353133

Start: 1328748

End: 1330220

Strand: Reverse

Name: mocR [H]

Synonym: BMULJ_04369

Alternate gene names: 189353133

Gene position: 1330220-1328748 (Counterclockwise)

Preceding gene: 189353135

Following gene: 189353132

Centisome position: 53.79

GC content: 72.3

Gene sequence:

>1473_bases
ATGACGACCGTTCCGCCGCTCGATTCCGTTCCGCCGGTGCCGCTCGATGCGCCGCTGTCCCGCGCGCCGGGCGCGCCTTC
GTTGCAGCGGCAACTGCTGCAGCGCGTGCGCGACGCGATTCTCGGCGGCGCGATGCCGGCCGGCACGCGCTTGCCGGGCA
CGCGCGCGCTCGCCGACCTGCTCGGCGTGTCGCGCAATACGACCGCGGCCGTGTACGAGCAGCTCGTCGCGGAGGGTTTT
CTGCAATCGGATCGTCGCGGCACGCGCGTGGTCGGGCTGTCGCGGCCGGCGGCGCCGCGCCGGCGAACGGCGCCGCCCGC
GGTTGCGCAGCGCCTCGAGCGGATTCGTCCGAGCGTCGGCGACAGCGACGACACGCACGGCTTCCGGCCCGGCGTGCCGG
CGCTGTCGCATTTCCCGATCGACGCGTGGCGGCACGCGATCGACCGCGCGCTGCGCCGCACGGGCCGCGACCTGCTCGCG
TACGGCGATCCGCTCGGCGAGCCTGCGCTGCGCGAATCGATCGCGCGCCATCTCGCGGTGACGCGCGGCGTGCGCTGCGA
TCCCGAGCAGATCGTGATCACCGAAGGCGCGCAGGGCGCGATCGCGCTGTGCGCGCAGCTGCTGACGAATCCCGGCGATA
CGGTGTGGGTCGAGGATCCCGGCTACCGCGGCGCGCGCACCGCGATGCAGGCGGCCAACCTCGACGTCGTGCCGATGCCG
GTCGATGCCGAAGGGCTGCGCGCGACCGAGGCGGACTGGCGCGAGCGGACGCCGCGCGTCGTCTATACGACGCCGTCGAA
CCAGTTCCCGACCGGCGCGGTGCTGTCGATTTCGCGGCGGCTCGCGCTGATCGACGCCGCGCGCCGGCATCGCGCCTGGA
TCGTCGAGGACGACTACGACAGCGAGTTCCGCCATACCGGCGAGCCGATCGGCGCGATGCACGGGCTCGCAGCCGATTCG
CCGGTCGTCTATCTCGGCTCGTTCAGCAAGACGATGTTTCCGGCATTGCGGATCGGCTTCCTCGTGCTGCCCGACGCATT
GCTCGCCGCCGTGCGGCCGGCGCTGCCCGAGATGCTGCGCGGCGGCACGCGTCACGTGCAGATCGCGCTCGCCGATTTCA
TCGAGACCGGAGAATACGGCCGGCATCTCGGCCGCATGCGCCGGCTTTATCGCGATCGGCGCCGCGCGCTGCTCGCGGCG
CTCGATGACAGCCTCAGCATCGAGCATCGCGTCGAAGGCGGGCCGTGCGGGCTGCATCTCGCGCTGCAACTGCCGGCACG
CTATCGCGACCGCGCGATCGTCGACGCGGCGCGCGCGCACGGCATCGGGCCGTTTGCGCTGTCCGCGTTTTCGATGCACG
CGAAATCGTCGCGCAACGGGCTCGTGCTCGGCTTCGGCAATACGTCGGCCGATGCGTTCGCCCCGATGCTGCGCACGCTG
TCCGCGATCGCGAAGCGGATCGGCGGCGCGTGA

Upstream 100 bases:

>100_bases
ACGATCGTAGTCGCGTCGAGGTACCATGAGAAGTGCCAGACATTGCCGAATTTATGGTGCCACGCATGTGGCGCCGATCC
GCTTGCCTTCGCCCGTTCCG

Downstream 100 bases:

>100_bases
CGCGCGGCGCGCGCAGGGTGAGGTGCGGGCACCCATCCGGCGCGCGCGCAACGCGGTTACACGTTCGACCCTCCGCGTAT
ACACTCGGCAAAAAAAAATC

Product: DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MTTVPPLDSVPPVPLDAPLSRAPGAPSLQRQLLQRVRDAILGGAMPAGTRLPGTRALADLLGVSRNTTAAVYEQLVAEGF
LQSDRRGTRVVGLSRPAAPRRRTAPPAVAQRLERIRPSVGDSDDTHGFRPGVPALSHFPIDAWRHAIDRALRRTGRDLLA
YGDPLGEPALRESIARHLAVTRGVRCDPEQIVITEGAQGAIALCAQLLTNPGDTVWVEDPGYRGARTAMQAANLDVVPMP
VDAEGLRATEADWRERTPRVVYTTPSNQFPTGAVLSISRRLALIDAARRHRAWIVEDDYDSEFRHTGEPIGAMHGLAADS
PVVYLGSFSKTMFPALRIGFLVLPDALLAAVRPALPEMLRGGTRHVQIALADFIETGEYGRHLGRMRRLYRDRRRALLAA
LDDSLSIEHRVEGGPCGLHLALQLPARYRDRAIVDAARAHGIGPFALSAFSMHAKSSRNGLVLGFGNTSADAFAPMLRTL
SAIAKRIGGA

Sequences:

>Translated_490_residues
MTTVPPLDSVPPVPLDAPLSRAPGAPSLQRQLLQRVRDAILGGAMPAGTRLPGTRALADLLGVSRNTTAAVYEQLVAEGF
LQSDRRGTRVVGLSRPAAPRRRTAPPAVAQRLERIRPSVGDSDDTHGFRPGVPALSHFPIDAWRHAIDRALRRTGRDLLA
YGDPLGEPALRESIARHLAVTRGVRCDPEQIVITEGAQGAIALCAQLLTNPGDTVWVEDPGYRGARTAMQAANLDVVPMP
VDAEGLRATEADWRERTPRVVYTTPSNQFPTGAVLSISRRLALIDAARRHRAWIVEDDYDSEFRHTGEPIGAMHGLAADS
PVVYLGSFSKTMFPALRIGFLVLPDALLAAVRPALPEMLRGGTRHVQIALADFIETGEYGRHLGRMRRLYRDRRRALLAA
LDDSLSIEHRVEGGPCGLHLALQLPARYRDRAIVDAARAHGIGPFALSAFSMHAKSSRNGLVLGFGNTSADAFAPMLRTL
SAIAKRIGGA
>Mature_489_residues
TTVPPLDSVPPVPLDAPLSRAPGAPSLQRQLLQRVRDAILGGAMPAGTRLPGTRALADLLGVSRNTTAAVYEQLVAEGFL
QSDRRGTRVVGLSRPAAPRRRTAPPAVAQRLERIRPSVGDSDDTHGFRPGVPALSHFPIDAWRHAIDRALRRTGRDLLAY
GDPLGEPALRESIARHLAVTRGVRCDPEQIVITEGAQGAIALCAQLLTNPGDTVWVEDPGYRGARTAMQAANLDVVPMPV
DAEGLRATEADWRERTPRVVYTTPSNQFPTGAVLSISRRLALIDAARRHRAWIVEDDYDSEFRHTGEPIGAMHGLAADSP
VVYLGSFSKTMFPALRIGFLVLPDALLAAVRPALPEMLRGGTRHVQIALADFIETGEYGRHLGRMRRLYRDRRRALLAAL
DDSLSIEHRVEGGPCGLHLALQLPARYRDRAIVDAARAHGIGPFALSAFSMHAKSSRNGLVLGFGNTSADAFAPMLRTLS
AIAKRIGGA

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=234, Percent_Identity=27.3504273504274, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI33469970, Length=234, Percent_Identity=27.3504273504274, Blast_Score=94, Evalue=4e-19,
Organism=Escherichia coli, GI1787710, Length=444, Percent_Identity=27.4774774774775, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1790797, Length=458, Percent_Identity=25.9825327510917, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786816, Length=334, Percent_Identity=26.0479041916168, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321236, Length=218, Percent_Identity=22.9357798165138, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52962; Mature: 52831

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVPPLDSVPPVPLDAPLSRAPGAPSLQRQLLQRVRDAILGGAMPAGTRLPGTRALADL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
LGVSRNTTAAVYEQLVAEGFLQSDRRGTRVVGLSRPAAPRRRTAPPAVAQRLERIRPSVG
HCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCC
DSDDTHGFRPGVPALSHFPIDAWRHAIDRALRRTGRDLLAYGDPLGEPALRESIARHLAV
CCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHH
TRGVRCDPEQIVITEGAQGAIALCAQLLTNPGDTVWVEDPGYRGARTAMQAANLDVVPMP
HCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCCEEECC
VDAEGLRATEADWRERTPRVVYTTPSNQFPTGAVLSISRRLALIDAARRHRAWIVEDDYD
CCCCCCCCCCCHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCC
SEFRHTGEPIGAMHGLAADSPVVYLGSFSKTMFPALRIGFLVLPDALLAAVRPALPEMLR
CHHHHCCCCHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGTRHVQIALADFIETGEYGRHLGRMRRLYRDRRRALLAALDDSLSIEHRVEGGPCGLHL
CCCCEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEE
ALQLPARYRDRAIVDAARAHGIGPFALSAFSMHAKSSRNGLVLGFGNTSADAFAPMLRTL
EEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHH
SAIAKRIGGA
HHHHHHHCCC
>Mature Secondary Structure 
TTVPPLDSVPPVPLDAPLSRAPGAPSLQRQLLQRVRDAILGGAMPAGTRLPGTRALADL
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
LGVSRNTTAAVYEQLVAEGFLQSDRRGTRVVGLSRPAAPRRRTAPPAVAQRLERIRPSVG
HCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCC
DSDDTHGFRPGVPALSHFPIDAWRHAIDRALRRTGRDLLAYGDPLGEPALRESIARHLAV
CCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHH
TRGVRCDPEQIVITEGAQGAIALCAQLLTNPGDTVWVEDPGYRGARTAMQAANLDVVPMP
HCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCCEEECC
VDAEGLRATEADWRERTPRVVYTTPSNQFPTGAVLSISRRLALIDAARRHRAWIVEDDYD
CCCCCCCCCCCHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCC
SEFRHTGEPIGAMHGLAADSPVVYLGSFSKTMFPALRIGFLVLPDALLAAVRPALPEMLR
CHHHHCCCCHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGTRHVQIALADFIETGEYGRHLGRMRRLYRDRRRALLAALDDSLSIEHRVEGGPCGLHL
CCCCEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEE
ALQLPARYRDRAIVDAARAHGIGPFALSAFSMHAKSSRNGLVLGFGNTSADAFAPMLRTL
EEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHH
SAIAKRIGGA
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]