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The map label for this gene is mprF [H]

Identifier: 189353119

GI number: 189353119

Start: 1304591

End: 1307185

Strand: Reverse

Name: mprF [H]

Synonym: BMULJ_04355

Alternate gene names: 189353119

Gene position: 1307185-1304591 (Counterclockwise)

Preceding gene: 189353120

Following gene: 189353118

Centisome position: 52.85

GC content: 69.52

Gene sequence:

>2595_bases
ATGTCCTCCCGCCACCCTGGTTCGCCCGGCCGTGCCGCGTCGGCGATCGGCCGTGTCGCGGCGCTGATCCGCAACGAGCG
CGTGCTGTCGCCGCTGCTCGCGCTCGGCATCGGCGTACTGCTGATCCTGGTTTTCCAGCACCTGTCACAATCGGTCGATT
ACCGGTCGGTGATCCGCGAGCTGCGCCACATGTCCGCCGGCGAGTGGGGCGCGTCGCTCGCCGCGACCGCGCTCAGCTAT
GTCGCGCTCGTCGCGCGCGACGCGGTCGGCCTGCGCTACGTCGCCGCGAAGGTGCCGCGCGCGGCGCTGTGGATCGGCGC
GATCGCCGGCTCCGCGCTCGGCAACGCGACGGGCTTCGGCGCGCTGACGGGCGGCGCGGTGCGCGCGCGCGTGTACGGCG
TGTCGGGCGTGACGCCCGCGCAGATCGGCCGCATGACGGTATTCACGAGCGCCACGCTCGCGCTCGCACTGGTATTGATG
ACGGCGATCGGCATGGTGTGCGTGCCCGGCACGCTCGGCGCCATGCTGCACGTCGCACCCGGCGCGATGACGGCGATCGG
TATCGTGCTGCTCGTCGTGCTGGCCGCGATGACGATGATGTGCGGCGCCGCCGCGCGGCCCGTCGTCACGCGCTTCAAGT
GGCTCGCGTTCGACGTGCCCGCGCGGCGCGACTTCGTCGCGCAGATCGTGTCCGCCGTGTTCGACGTGATCGCCGCGGGT
CTCACGCTCTGGGTGCTGCTGCCGGCCGCGCCGGTCGGCTTCCCGACGTTCATCACTGTCTACGCGGCCGCGCTGCTGCT
CGGCATGATCGGCCATACGCCGGGCGGGATCGGCGTGTTCGAAGCGGCGATGGTATTCACGCTCGGCAGCGCCGTGCCCG
CGCATGTGATGCTGGCCGCGCTGATCGCCTATCGCGCGATCTACTTCGGCGTGCCGCTCGTGCTGTCCGCGGGGCTGCTC
GCCGCATTCGAGGGTCGCGCGCTGCGGCGCCGGCTCGTCTCGCGTCAGGCCGCGCGCGTGTCGCAGCTCGCACCGCTGTT
CCTGAGCCTCGTCACGTTCGCGGTCGGCAGCATGCTGGTGATCTCGAGCGCGACGCCCGCGTTCTGGCATCGGATCGCGA
TCCTGCGCAACGTCATCCCGCTCTGGGTGCTCGAAGGCTCGCAGGTCATCTGCAGCGTGCTCGGCGTCGCGCTGCTGTTC
GTCGCGCGCGGGCTGCTGCGCCGCCTCGACGGCGCGTGGTGGATGACCTTCGTGCTGACGCTCGCCAGCCTCGCGCTGTC
GCTCGCGAAGGGTCTCGCATTCGTCGAAGCGGGCGTGCTCGGCACGCTGCTGGTCCTGCTGCTCGTGAGCCGGCGCCGCT
TCAACCGTCATTCGTCGCTGCTCGCCGAGCGCTTCACGCTGAGCTGGTTCGTGTCGGTGACGATGGTGCTGATCCTCGCG
GTGTGGGTGCTGTGCTTCGCGTTCCGCGACGTGCCTTACACGCGCGAGCTGTGGTCGCATTTCTCGTTCGATGCGCGCGC
GCCGCGGGCGCTGCGCGCGACGCTCGCGGCCGGCGTGTTCGTCGCGATGTTCGCGCTGTGGCAACTGCTGCGTCCGGCGC
CCGGCCGCTTCACGAAGCCCACGCCGCAGGATCTGCTCGACGCCGAGCGGATCGTCCGCGCGCAGGAGTGCAGTGATGCC
GGTCTCGCGCTGATGGGCGACAAGTCATTCCTGTTCTCCGACTCGCGCCGCGCGTTCCTGATGTATGCGAAATACGGCCG
CACCTGGGCCGCGCTCTACGATCCGGTCGGCCCGCGCGACGAGTGGCCGGCGCTGATCGGCAAGTTCATCGCGCTCGCGC
ACCGTCACGGCGGGCGCGCGGCGTTCTATCAGGTGCGCGCGAATGCGCTGCCGCTCTATCTCGACGCCGGGCTCACGCTG
ATGAAGCTCGGCGAGGAAGCGCATATCGCGCTCGACGAATTCGATCTGAAGGGCTCGCATCGCTCGCATCTGCGCTATGC
GCTGCGTCGCGGCGACAAGGACGCGCTGTCGGTCGAGGTCATCGCGCCGGCCGACGTGCCGGCCGCGCTGCCGGTGCTGC
GCGAGATCTCGAACGTGTGGCTCGACACGCGTGATGCGCGCGAGAAGAGCTTTTCGGTCGCCGCGTTCCACGACGGCTAT
CTCGCGACGCAGTCGGTAATGCTCGTGCGCCAGGCCGACAAGCCGATCGCGTTCGTCACGTTCATGACGACCGACCTCAA
TACCGAGGCGACGGTCGGCGTGATGCGCCATCTGCCGGAGGCGTCGCCGTACGCGATGGAGTATCTGTTTACGCAGCTCG
CGCTGCATCTGAAGGAAGCGGGTTTCCGCAAGCTGAGCCTCGGCATCGCGCCGTTCTCGGGGATGGGGGCGGCGAAGATG
CCGTCGCCGTGGCACCGGGTCGGGCTGATGGTGTGGCGCTTCGGCGGACGCTTCTACAACTTCCGCGGCTTGCGTGCGTT
CAAGAGCAAGTTCGAACCGCACTGGGAACCGCGCTACCTCGCGGCGTCCGGTTCGGTCGGCGTGTTCGTCACGCTCGCGG
ATCTGTCATTGCTGGCTGGAGGTCGGCGCTCATGA

Upstream 100 bases:

>100_bases
CGCTCGCGTTGCTCCGCAGCGGGCCGCCCATGCAGAACAACCCGATTCGTCGCCGCCTCGCATCCGCGCCGCGACCGCTA
TGCATCACCGCGAATAATCT

Downstream 100 bases:

>100_bases
TGTCGAAGAAGGGAATCGCGCGGGCCGCCATCGCCTGCGCGGGATGGATGCTGGCCGGCGCCGCGCTTGCCGCGCAGCCG
GTCGCGGCGAAGACCGAAAC

Product: hypothetical protein

Products: NA

Alternate protein names: Lysylphosphatidylglycerol synthase; LPG synthase; Multiple peptide resistance factor [H]

Number of amino acids: Translated: 864; Mature: 863

Protein sequence:

>864_residues
MSSRHPGSPGRAASAIGRVAALIRNERVLSPLLALGIGVLLILVFQHLSQSVDYRSVIRELRHMSAGEWGASLAATALSY
VALVARDAVGLRYVAAKVPRAALWIGAIAGSALGNATGFGALTGGAVRARVYGVSGVTPAQIGRMTVFTSATLALALVLM
TAIGMVCVPGTLGAMLHVAPGAMTAIGIVLLVVLAAMTMMCGAAARPVVTRFKWLAFDVPARRDFVAQIVSAVFDVIAAG
LTLWVLLPAAPVGFPTFITVYAAALLLGMIGHTPGGIGVFEAAMVFTLGSAVPAHVMLAALIAYRAIYFGVPLVLSAGLL
AAFEGRALRRRLVSRQAARVSQLAPLFLSLVTFAVGSMLVISSATPAFWHRIAILRNVIPLWVLEGSQVICSVLGVALLF
VARGLLRRLDGAWWMTFVLTLASLALSLAKGLAFVEAGVLGTLLVLLLVSRRRFNRHSSLLAERFTLSWFVSVTMVLILA
VWVLCFAFRDVPYTRELWSHFSFDARAPRALRATLAAGVFVAMFALWQLLRPAPGRFTKPTPQDLLDAERIVRAQECSDA
GLALMGDKSFLFSDSRRAFLMYAKYGRTWAALYDPVGPRDEWPALIGKFIALAHRHGGRAAFYQVRANALPLYLDAGLTL
MKLGEEAHIALDEFDLKGSHRSHLRYALRRGDKDALSVEVIAPADVPAALPVLREISNVWLDTRDAREKSFSVAAFHDGY
LATQSVMLVRQADKPIAFVTFMTTDLNTEATVGVMRHLPEASPYAMEYLFTQLALHLKEAGFRKLSLGIAPFSGMGAAKM
PSPWHRVGLMVWRFGGRFYNFRGLRAFKSKFEPHWEPRYLAASGSVGVFVTLADLSLLAGGRRS

Sequences:

>Translated_864_residues
MSSRHPGSPGRAASAIGRVAALIRNERVLSPLLALGIGVLLILVFQHLSQSVDYRSVIRELRHMSAGEWGASLAATALSY
VALVARDAVGLRYVAAKVPRAALWIGAIAGSALGNATGFGALTGGAVRARVYGVSGVTPAQIGRMTVFTSATLALALVLM
TAIGMVCVPGTLGAMLHVAPGAMTAIGIVLLVVLAAMTMMCGAAARPVVTRFKWLAFDVPARRDFVAQIVSAVFDVIAAG
LTLWVLLPAAPVGFPTFITVYAAALLLGMIGHTPGGIGVFEAAMVFTLGSAVPAHVMLAALIAYRAIYFGVPLVLSAGLL
AAFEGRALRRRLVSRQAARVSQLAPLFLSLVTFAVGSMLVISSATPAFWHRIAILRNVIPLWVLEGSQVICSVLGVALLF
VARGLLRRLDGAWWMTFVLTLASLALSLAKGLAFVEAGVLGTLLVLLLVSRRRFNRHSSLLAERFTLSWFVSVTMVLILA
VWVLCFAFRDVPYTRELWSHFSFDARAPRALRATLAAGVFVAMFALWQLLRPAPGRFTKPTPQDLLDAERIVRAQECSDA
GLALMGDKSFLFSDSRRAFLMYAKYGRTWAALYDPVGPRDEWPALIGKFIALAHRHGGRAAFYQVRANALPLYLDAGLTL
MKLGEEAHIALDEFDLKGSHRSHLRYALRRGDKDALSVEVIAPADVPAALPVLREISNVWLDTRDAREKSFSVAAFHDGY
LATQSVMLVRQADKPIAFVTFMTTDLNTEATVGVMRHLPEASPYAMEYLFTQLALHLKEAGFRKLSLGIAPFSGMGAAKM
PSPWHRVGLMVWRFGGRFYNFRGLRAFKSKFEPHWEPRYLAASGSVGVFVTLADLSLLAGGRRS
>Mature_863_residues
SSRHPGSPGRAASAIGRVAALIRNERVLSPLLALGIGVLLILVFQHLSQSVDYRSVIRELRHMSAGEWGASLAATALSYV
ALVARDAVGLRYVAAKVPRAALWIGAIAGSALGNATGFGALTGGAVRARVYGVSGVTPAQIGRMTVFTSATLALALVLMT
AIGMVCVPGTLGAMLHVAPGAMTAIGIVLLVVLAAMTMMCGAAARPVVTRFKWLAFDVPARRDFVAQIVSAVFDVIAAGL
TLWVLLPAAPVGFPTFITVYAAALLLGMIGHTPGGIGVFEAAMVFTLGSAVPAHVMLAALIAYRAIYFGVPLVLSAGLLA
AFEGRALRRRLVSRQAARVSQLAPLFLSLVTFAVGSMLVISSATPAFWHRIAILRNVIPLWVLEGSQVICSVLGVALLFV
ARGLLRRLDGAWWMTFVLTLASLALSLAKGLAFVEAGVLGTLLVLLLVSRRRFNRHSSLLAERFTLSWFVSVTMVLILAV
WVLCFAFRDVPYTRELWSHFSFDARAPRALRATLAAGVFVAMFALWQLLRPAPGRFTKPTPQDLLDAERIVRAQECSDAG
LALMGDKSFLFSDSRRAFLMYAKYGRTWAALYDPVGPRDEWPALIGKFIALAHRHGGRAAFYQVRANALPLYLDAGLTLM
KLGEEAHIALDEFDLKGSHRSHLRYALRRGDKDALSVEVIAPADVPAALPVLREISNVWLDTRDAREKSFSVAAFHDGYL
ATQSVMLVRQADKPIAFVTFMTTDLNTEATVGVMRHLPEASPYAMEYLFTQLALHLKEAGFRKLSLGIAPFSGMGAAKMP
SPWHRVGLMVWRFGGRFYNFRGLRAFKSKFEPHWEPRYLAASGSVGVFVTLADLSLLAGGRRS

Specific function: Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes

COG id: COG2898

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LPG synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787006, Length=311, Percent_Identity=24.1157556270096, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR022791 [H]

Pfam domain/function: PF03706 UPF0104 [H]

EC number: =2.3.2.3 [H]

Molecular weight: Translated: 93319; Mature: 93188

Theoretical pI: Translated: 10.98; Mature: 10.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRHPGSPGRAASAIGRVAALIRNERVLSPLLALGIGVLLILVFQHLSQSVDYRSVIRE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LRHMSAGEWGASLAATALSYVALVARDAVGLRYVAAKVPRAALWIGAIAGSALGNATGFG
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCC
ALTGGAVRARVYGVSGVTPAQIGRMTVFTSATLALALVLMTAIGMVCVPGTLGAMLHVAP
CCCCCHHEEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
GAMTAIGIVLLVVLAAMTMMCGAAARPVVTRFKWLAFDVPARRDFVAQIVSAVFDVIAAG
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LTLWVLLPAAPVGFPTFITVYAAALLLGMIGHTPGGIGVFEAAMVFTLGSAVPAHVMLAA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
LIAYRAIYFGVPLVLSAGLLAAFEGRALRRRLVSRQAARVSQLAPLFLSLVTFAVGSMLV
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISSATPAFWHRIAILRNVIPLWVLEGSQVICSVLGVALLFVARGLLRRLDGAWWMTFVLT
CCCCCHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LASLALSLAKGLAFVEAGVLGTLLVLLLVSRRRFNRHSSLLAERFTLSWFVSVTMVLILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWVLCFAFRDVPYTRELWSHFSFDARAPRALRATLAAGVFVAMFALWQLLRPAPGRFTKP
HHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TPQDLLDAERIVRAQECSDAGLALMGDKSFLFSDSRRAFLMYAKYGRTWAALYDPVGPRD
CHHHHHHHHHHHHHHHCCCCCEEEECCCHHEECCCCCEEEEEEHHCCCHHHHHCCCCCCC
EWPALIGKFIALAHRHGGRAAFYQVRANALPLYLDAGLTLMKLGEEAHIALDEFDLKGSH
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCHHHHCCCHHEEEEECCCCCCCH
RSHLRYALRRGDKDALSVEVIAPADVPAALPVLREISNVWLDTRDAREKSFSVAAFHDGY
HHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHCCEEEEECCCH
LATQSVMLVRQADKPIAFVTFMTTDLNTEATVGVMRHLPEASPYAMEYLFTQLALHLKEA
HHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
GFRKLSLGIAPFSGMGAAKMPSPWHRVGLMVWRFGGRFYNFRGLRAFKSKFEPHWEPRYL
CCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEECCHHHHHHHHCCCCCCCCCEE
AASGSVGVFVTLADLSLLAGGRRS
EECCCCEEEEEHHHHHHHCCCCCC
>Mature Secondary Structure 
SSRHPGSPGRAASAIGRVAALIRNERVLSPLLALGIGVLLILVFQHLSQSVDYRSVIRE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LRHMSAGEWGASLAATALSYVALVARDAVGLRYVAAKVPRAALWIGAIAGSALGNATGFG
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCC
ALTGGAVRARVYGVSGVTPAQIGRMTVFTSATLALALVLMTAIGMVCVPGTLGAMLHVAP
CCCCCHHEEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
GAMTAIGIVLLVVLAAMTMMCGAAARPVVTRFKWLAFDVPARRDFVAQIVSAVFDVIAAG
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LTLWVLLPAAPVGFPTFITVYAAALLLGMIGHTPGGIGVFEAAMVFTLGSAVPAHVMLAA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
LIAYRAIYFGVPLVLSAGLLAAFEGRALRRRLVSRQAARVSQLAPLFLSLVTFAVGSMLV
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISSATPAFWHRIAILRNVIPLWVLEGSQVICSVLGVALLFVARGLLRRLDGAWWMTFVLT
CCCCCHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LASLALSLAKGLAFVEAGVLGTLLVLLLVSRRRFNRHSSLLAERFTLSWFVSVTMVLILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWVLCFAFRDVPYTRELWSHFSFDARAPRALRATLAAGVFVAMFALWQLLRPAPGRFTKP
HHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TPQDLLDAERIVRAQECSDAGLALMGDKSFLFSDSRRAFLMYAKYGRTWAALYDPVGPRD
CHHHHHHHHHHHHHHHCCCCCEEEECCCHHEECCCCCEEEEEEHHCCCHHHHHCCCCCCC
EWPALIGKFIALAHRHGGRAAFYQVRANALPLYLDAGLTLMKLGEEAHIALDEFDLKGSH
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCHHHHCCCHHEEEEECCCCCCCH
RSHLRYALRRGDKDALSVEVIAPADVPAALPVLREISNVWLDTRDAREKSFSVAAFHDGY
HHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHCCEEEEECCCH
LATQSVMLVRQADKPIAFVTFMTTDLNTEATVGVMRHLPEASPYAMEYLFTQLALHLKEA
HHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
GFRKLSLGIAPFSGMGAAKMPSPWHRVGLMVWRFGGRFYNFRGLRAFKSKFEPHWEPRYL
CCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEECCHHHHHHHHCCCCCCCCCEE
AASGSVGVFVTLADLSLLAGGRRS
EECCCCEEEEEHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA