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The map label for this gene is dgoT [H]

Identifier: 189353116

GI number: 189353116

Start: 1300285

End: 1301595

Strand: Direct

Name: dgoT [H]

Synonym: BMULJ_04352

Alternate gene names: 189353116

Gene position: 1300285-1301595 (Clockwise)

Preceding gene: 189353115

Following gene: 189353117

Centisome position: 52.58

GC content: 68.95

Gene sequence:

>1311_bases
ATGCCACGCATTCGATGGGCCATGATCCTGATGTGCTTTCTGGCCAACGTCATCAACTTCATCGATCGCGCGAACCTCGC
GATCGCGGCGCCCAGCATACGCGCGGATCTCGGCCTCGACGCGGTCGGCATGGGTCTCGTGCTCAGCGCGTTCTTCTGGA
CCTACGCGTTTCTGCAGCTGCCGGCCGGCTGGTTCATCGACAAGGTCGGCGTGCGCGTGAGCCTCGCGCTCGCGGTCGGC
TGGTGGTCGCTGTTTACGGTCGCGACCGGCGCGGCGCGCGGGCTGGCCCAGCTCGTCGGCGTGCGGCTGATGCTCGGCGT
CGGCGAAGCGGCCGCGATCCCGTCGTTCGCGAAGGTCGCGTTCAACTGGTTCCCGCGCAGCGAACGCGGCCTCGCGAGCA
GCATCTTCGACAGCGGCTCGCGCGTCGGCTCGGCGCTGTCATTGCCGCTCGTCGCATGGCTGATCTCGATCGTCGGCTGG
CGCGGCTCGTTCGCGGTCACCGGCGCGATCGGCATCGTGTGGGCCGCTGCGTGGTGGTTCGTCTATCGCGACCCCGAACG
CTATCGCCACATCGCGCCCGATGCGGTCGACGCGCTGCTCGCGCAGCGCGGCGCACCGGCCGTCGCCGACAAGGCCGATC
TGCCGACCGTGTCGTGGCTCGACCTGTTTCGCTACCGCACCGTGTGGGGCATGATGATCGGCCTGTTCTGCCTGAACTTC
GCGATCTACTTCTTCATCACGTGGTTCCCGAGCTATCTGCTGCAGTCGCGCGGCTTCTCGCTCGCGTCGCTCGGCACCTG
GGGCATGCTGCCCGCGCTGCTCGCGATTCCGGGCGGCTGGCTCGGCGGCTACGTGTCGGACAGCCTGTTCCGCCGCGGCT
GGAGCGCGACCGCCGCGCGCAAGACCTGTCTCGTGCTCGGGATGCTGCTGTCGTCGTCGATCGCGCTGTCCGCGTTCGTC
GACAACGTGTGGGTCTGTCTCGCACTGTTCGCGCTCGCCTATGCGAGCCTGTCGTTCGCGGGGGCGAACGTGTGGACGCT
CGTCGGCGAAGTCGCGCCGACGCCCGCGCACGTTGCGTCGCTCGGCGGCATCCAGAACTTCGCAGGCAATCTCGCGGGGA
TCTTCATCACGACGTTCACCGGCGTGATGCTGTCGCTGACCAAGGGCTCGTTCGTCGTGCCGCTCGCGGTGGCCGGCGCG
CTCTGTGTGGTCGGCGCGCTGTCCTACCTGTTCATCGTCGGCAAGGTCGAGCCGCTGCCGGTCCCGCGCGGCCGCGCAGC
CGCGCGCAGCGCCGAGCCGAACGCGGCGTAA

Upstream 100 bases:

>100_bases
CGACCGCGCGCCGCAGCCGGCGTAACCGTCATCGCCTTCGAGGCGGCCGGCGCCGCGGATCGCCGGTCGCCCGCCACGAC
ATTCCGCGCGGAGACACCTC

Downstream 100 bases:

>100_bases
TGCGGGTGGCCGGCGACGCGCGGTGGCAATGGCCCGCCCGCGCGTCGCCGCGTCGCTTTCCTTTTCCGCGCACGCATCGG
ACAATGGCTCGCGCCCGCCG

Product: D-galactonate transporter

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MPRIRWAMILMCFLANVINFIDRANLAIAAPSIRADLGLDAVGMGLVLSAFFWTYAFLQLPAGWFIDKVGVRVSLALAVG
WWSLFTVATGAARGLAQLVGVRLMLGVGEAAAIPSFAKVAFNWFPRSERGLASSIFDSGSRVGSALSLPLVAWLISIVGW
RGSFAVTGAIGIVWAAAWWFVYRDPERYRHIAPDAVDALLAQRGAPAVADKADLPTVSWLDLFRYRTVWGMMIGLFCLNF
AIYFFITWFPSYLLQSRGFSLASLGTWGMLPALLAIPGGWLGGYVSDSLFRRGWSATAARKTCLVLGMLLSSSIALSAFV
DNVWVCLALFALAYASLSFAGANVWTLVGEVAPTPAHVASLGGIQNFAGNLAGIFITTFTGVMLSLTKGSFVVPLAVAGA
LCVVGALSYLFIVGKVEPLPVPRGRAAARSAEPNAA

Sequences:

>Translated_436_residues
MPRIRWAMILMCFLANVINFIDRANLAIAAPSIRADLGLDAVGMGLVLSAFFWTYAFLQLPAGWFIDKVGVRVSLALAVG
WWSLFTVATGAARGLAQLVGVRLMLGVGEAAAIPSFAKVAFNWFPRSERGLASSIFDSGSRVGSALSLPLVAWLISIVGW
RGSFAVTGAIGIVWAAAWWFVYRDPERYRHIAPDAVDALLAQRGAPAVADKADLPTVSWLDLFRYRTVWGMMIGLFCLNF
AIYFFITWFPSYLLQSRGFSLASLGTWGMLPALLAIPGGWLGGYVSDSLFRRGWSATAARKTCLVLGMLLSSSIALSAFV
DNVWVCLALFALAYASLSFAGANVWTLVGEVAPTPAHVASLGGIQNFAGNLAGIFITTFTGVMLSLTKGSFVVPLAVAGA
LCVVGALSYLFIVGKVEPLPVPRGRAAARSAEPNAA
>Mature_435_residues
PRIRWAMILMCFLANVINFIDRANLAIAAPSIRADLGLDAVGMGLVLSAFFWTYAFLQLPAGWFIDKVGVRVSLALAVGW
WSLFTVATGAARGLAQLVGVRLMLGVGEAAAIPSFAKVAFNWFPRSERGLASSIFDSGSRVGSALSLPLVAWLISIVGWR
GSFAVTGAIGIVWAAAWWFVYRDPERYRHIAPDAVDALLAQRGAPAVADKADLPTVSWLDLFRYRTVWGMMIGLFCLNFA
IYFFITWFPSYLLQSRGFSLASLGTWGMLPALLAIPGGWLGGYVSDSLFRRGWSATAARKTCLVLGMLLSSSIALSAFVD
NVWVCLALFALAYASLSFAGANVWTLVGEVAPTPAHVASLGGIQNFAGNLAGIFITTFTGVMLSLTKGSFVVPLAVAGAL
CVVGALSYLFIVGKVEPLPVPRGRAAARSAEPNAA

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=402, Percent_Identity=26.1194029850746, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI9945322, Length=454, Percent_Identity=24.6696035242291, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI9966811, Length=457, Percent_Identity=22.7571115973742, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI21322234, Length=405, Percent_Identity=23.7037037037037, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI6912666, Length=279, Percent_Identity=26.8817204301075, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI148743791, Length=330, Percent_Identity=22.4242424242424, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI148728191, Length=267, Percent_Identity=23.5955056179775, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI223718438, Length=404, Percent_Identity=22.7722772277228, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87082320, Length=421, Percent_Identity=36.104513064133, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI2367379, Length=424, Percent_Identity=34.9056603773585, Blast_Score=245, Evalue=5e-66,
Organism=Escherichia coli, GI1789515, Length=436, Percent_Identity=34.6330275229358, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1789152, Length=432, Percent_Identity=34.4907407407407, Blast_Score=232, Evalue=4e-62,
Organism=Escherichia coli, GI2367193, Length=342, Percent_Identity=28.9473684210526, Blast_Score=151, Evalue=8e-38,
Organism=Escherichia coli, GI87082071, Length=405, Percent_Identity=26.6666666666667, Blast_Score=83, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17535049, Length=417, Percent_Identity=25.4196642685851, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17554148, Length=396, Percent_Identity=26.2626262626263, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17552542, Length=461, Percent_Identity=22.9934924078091, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI115533554, Length=339, Percent_Identity=25.6637168141593, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI115533556, Length=339, Percent_Identity=25.6637168141593, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI193205400, Length=338, Percent_Identity=25.4437869822485, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17554962, Length=333, Percent_Identity=23.1231231231231, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71997452, Length=394, Percent_Identity=22.8426395939086, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17560030, Length=359, Percent_Identity=23.3983286908078, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI32565916, Length=244, Percent_Identity=24.1803278688525, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI32565914, Length=350, Percent_Identity=22.8571428571429, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI86561091, Length=261, Percent_Identity=25.2873563218391, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25141341, Length=244, Percent_Identity=23.7704918032787, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25141318, Length=244, Percent_Identity=23.7704918032787, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25141316, Length=244, Percent_Identity=23.7704918032787, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71991448, Length=177, Percent_Identity=24.8587570621469, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71991453, Length=177, Percent_Identity=24.8587570621469, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17566884, Length=212, Percent_Identity=25, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17561498, Length=217, Percent_Identity=25.3456221198157, Blast_Score=65, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24648416, Length=458, Percent_Identity=24.6724890829694, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI21356189, Length=458, Percent_Identity=24.6724890829694, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24583789, Length=429, Percent_Identity=25.6410256410256, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI62484226, Length=401, Percent_Identity=26.1845386533666, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24580790, Length=359, Percent_Identity=25.9052924791086, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI19920686, Length=394, Percent_Identity=25.1269035532995, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28573299, Length=308, Percent_Identity=25.974025974026, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24641682, Length=433, Percent_Identity=25.1732101616628, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24584153, Length=262, Percent_Identity=25.9541984732824, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI20129235, Length=363, Percent_Identity=26.9972451790634, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24658658, Length=456, Percent_Identity=21.7105263157895, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI20130167, Length=398, Percent_Identity=24.6231155778894, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI20130135, Length=318, Percent_Identity=25.1572327044025, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24655271, Length=318, Percent_Identity=25.1572327044025, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45550460, Length=412, Percent_Identity=23.0582524271845, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24655255, Length=356, Percent_Identity=24.438202247191, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28573708, Length=346, Percent_Identity=24.5664739884393, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28573707, Length=346, Percent_Identity=24.5664739884393, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19922400, Length=363, Percent_Identity=24.2424242424242, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24654215, Length=359, Percent_Identity=24.2339832869081, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24639764, Length=331, Percent_Identity=21.7522658610272, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24653727, Length=414, Percent_Identity=23.4299516908213, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24658666, Length=430, Percent_Identity=20.4651162790698, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24658674, Length=435, Percent_Identity=20.4597701149425, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46533; Mature: 46402

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCHHHCCCCCCCC
>Mature Secondary Structure 
PRIRWAMILMCFLANVINFIDRANLAIAAPSIRADLGLDAVGMGLVLSAFFWTYAFLQL
CCHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHC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CCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]