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The map label for this gene is uxuA [H]

Identifier: 189353115

GI number: 189353115

Start: 1299157

End: 1300209

Strand: Direct

Name: uxuA [H]

Synonym: BMULJ_04351

Alternate gene names: 189353115

Gene position: 1299157-1300209 (Clockwise)

Preceding gene: 189353111

Following gene: 189353116

Centisome position: 52.53

GC content: 66.95

Gene sequence:

>1053_bases
ATGTCTTTCCGTTGGTACGGCGAGTCCGATCCGGTCTCGCTGCAGTACATCCGCCAGATTCCCGGCGTCACGCATATCGT
GTCCGCGATCTACGACGAACCGGTCGGCGAAGTGTGGCCCGCGCACAAGATCGACGCACTGAAGGCGACGATCGAGCGTG
CGGGGCTGCGCTTCGAGGTCGTCGAGTCGGTGCCCGTCCACGAGGACATCAAGCTCGGCAAGCCGAGCCGCGACCGGCTG
ATCGACAACTACCGTCAGACGATCCGCCATCTCGGCGCGGCCGGCGTGCGCGTCGTCTGCTACAACTTCATGCCGGTGTT
CGACTGGACGCGCACCGAGCTGTCGAAGACGCTCGACGACGGCTCGACCTGTCTCGCATTCAGCACCGAGGCGGTCGAGC
GGATCGACCCGAGCGCCGGCATCGCGCTGCCGGGCTGGGACACGAGCTACCGGCCCGATGCGTTGCAGGCGTTGCTCGCC
GAGTATCGCGACGTCGACGAAGCCGCGCTGTGGGCGAATCTCGAATACTTCCTGAAGGCCGTGATCCCGGTCGCCGAAGA
AGCGGGCGTCAAGATGGCGATCCACCCGGACGATCCGCCGCGTCCGATCTTCGGGCTGCCGCGCATCGTGAAGAACCGCG
ACGATCTCGCGCGGATCCTTCGCATCGTCGACACGCCCGCGAACGGCCTCACGCTCTGCTCGGGCTCGCTCGGCGCGGGC
CCGCAGAACGACGTCGAGGCGCTGGTGCGCGAGTTCGGCGCGATGGGTCGCATCCACTTCGCGCACATCCGCAACGTGAA
GGTCGACGCGGCCGGCAATTTCGAGGAAACGGCGCACCTGTCGAGCTGCGGATCGCTCGACATCGCCGCGATCGTGAAGG
CGTATCACGACACGGGCTTCACCGGCTACGTGCGGCCCGATCACGGCCGGATGATCTGGGGCGAGACCGGCAAGCCCGGC
TATGGCCTCTACGATCGCGCGCTCGGCGCGGTGTATCTCAACGGACTGTGGGAAGCGCTCGCGAAGTTCGACCGCGCGCC
GCAGCCGGCGTAA

Upstream 100 bases:

>100_bases
GCATACCAATCATAATGCGCGCATCGACGACGGAGGTCGCGCCCGCCGTGGCCGCCCGTCGCTCACGCCTCACCGCCCAT
CAGGAGCCGCTCCCGTGAAG

Downstream 100 bases:

>100_bases
CCGTCATCGCCTTCGAGGCGGCCGGCGCCGCGGATCGCCGGTCGCCCGCCACGACATTCCGCGCGGAGACACCTCATGCC
ACGCATTCGATGGGCCATGA

Product: mannonate dehydratase

Products: NA

Alternate protein names: D-mannonate hydrolase [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSFRWYGESDPVSLQYIRQIPGVTHIVSAIYDEPVGEVWPAHKIDALKATIERAGLRFEVVESVPVHEDIKLGKPSRDRL
IDNYRQTIRHLGAAGVRVVCYNFMPVFDWTRTELSKTLDDGSTCLAFSTEAVERIDPSAGIALPGWDTSYRPDALQALLA
EYRDVDEAALWANLEYFLKAVIPVAEEAGVKMAIHPDDPPRPIFGLPRIVKNRDDLARILRIVDTPANGLTLCSGSLGAG
PQNDVEALVREFGAMGRIHFAHIRNVKVDAAGNFEETAHLSSCGSLDIAAIVKAYHDTGFTGYVRPDHGRMIWGETGKPG
YGLYDRALGAVYLNGLWEALAKFDRAPQPA

Sequences:

>Translated_350_residues
MSFRWYGESDPVSLQYIRQIPGVTHIVSAIYDEPVGEVWPAHKIDALKATIERAGLRFEVVESVPVHEDIKLGKPSRDRL
IDNYRQTIRHLGAAGVRVVCYNFMPVFDWTRTELSKTLDDGSTCLAFSTEAVERIDPSAGIALPGWDTSYRPDALQALLA
EYRDVDEAALWANLEYFLKAVIPVAEEAGVKMAIHPDDPPRPIFGLPRIVKNRDDLARILRIVDTPANGLTLCSGSLGAG
PQNDVEALVREFGAMGRIHFAHIRNVKVDAAGNFEETAHLSSCGSLDIAAIVKAYHDTGFTGYVRPDHGRMIWGETGKPG
YGLYDRALGAVYLNGLWEALAKFDRAPQPA
>Mature_349_residues
SFRWYGESDPVSLQYIRQIPGVTHIVSAIYDEPVGEVWPAHKIDALKATIERAGLRFEVVESVPVHEDIKLGKPSRDRLI
DNYRQTIRHLGAAGVRVVCYNFMPVFDWTRTELSKTLDDGSTCLAFSTEAVERIDPSAGIALPGWDTSYRPDALQALLAE
YRDVDEAALWANLEYFLKAVIPVAEEAGVKMAIHPDDPPRPIFGLPRIVKNRDDLARILRIVDTPANGLTLCSGSLGAGP
QNDVEALVREFGAMGRIHFAHIRNVKVDAAGNFEETAHLSSCGSLDIAAIVKAYHDTGFTGYVRPDHGRMIWGETGKPGY
GLYDRALGAVYLNGLWEALAKFDRAPQPA

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1312

COG function: function code G; D-mannonate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannonate dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1790778, Length=391, Percent_Identity=40.153452685422, Blast_Score=265, Evalue=3e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004628
- InterPro:   IPR013022 [H]

Pfam domain/function: PF03786 UxuA [H]

EC number: =4.2.1.8 [H]

Molecular weight: Translated: 38625; Mature: 38494

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFRWYGESDPVSLQYIRQIPGVTHIVSAIYDEPVGEVWPAHKIDALKATIERAGLRFEV
CCEEECCCCCCHHHHHHHHCCCHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHCCCEEEE
VESVPVHEDIKLGKPSRDRLIDNYRQTIRHLGAAGVRVVCYNFMPVFDWTRTELSKTLDD
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCC
GSTCLAFSTEAVERIDPSAGIALPGWDTSYRPDALQALLAEYRDVDEAALWANLEYFLKA
CCEEEEECHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
VIPVAEEAGVKMAIHPDDPPRPIFGLPRIVKNRDDLARILRIVDTPANGLTLCSGSLGAG
HHHHHHHCCCEEEECCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCCCEEEECCCCCCC
PQNDVEALVREFGAMGRIHFAHIRNVKVDAAGNFEETAHLSSCGSLDIAAIVKAYHDTGF
CCHHHHHHHHHHCCCCCEEEEEECEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHCCCC
TGYVRPDHGRMIWGETGKPGYGLYDRALGAVYLNGLWEALAKFDRAPQPA
EEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SFRWYGESDPVSLQYIRQIPGVTHIVSAIYDEPVGEVWPAHKIDALKATIERAGLRFEV
CEEECCCCCCHHHHHHHHCCCHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHCCCEEEE
VESVPVHEDIKLGKPSRDRLIDNYRQTIRHLGAAGVRVVCYNFMPVFDWTRTELSKTLDD
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCC
GSTCLAFSTEAVERIDPSAGIALPGWDTSYRPDALQALLAEYRDVDEAALWANLEYFLKA
CCEEEEECHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
VIPVAEEAGVKMAIHPDDPPRPIFGLPRIVKNRDDLARILRIVDTPANGLTLCSGSLGAG
HHHHHHHCCCEEEECCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCCCEEEECCCCCCC
PQNDVEALVREFGAMGRIHFAHIRNVKVDAAGNFEETAHLSSCGSLDIAAIVKAYHDTGF
CCHHHHHHHHHHCCCCCEEEEEECEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHCCCC
TGYVRPDHGRMIWGETGKPGYGLYDRALGAVYLNGLWEALAKFDRAPQPA
EEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA