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The map label for this gene is yncB [H]

Identifier: 189353052

GI number: 189353052

Start: 1219856

End: 1220899

Strand: Direct

Name: yncB [H]

Synonym: BMULJ_04286

Alternate gene names: 189353052

Gene position: 1219856-1220899 (Clockwise)

Preceding gene: 189353051

Following gene: 189353053

Centisome position: 49.32

GC content: 68.3

Gene sequence:

>1044_bases
ATGTCGCAAAGCAAGACCGCAAACCGCCGTATCGTCCTCAATTCGCGCCCGGTCGGCGCGCCCACCGCCAACGACTTCCG
CCTCGAAACCGGCGACGTGCCGACGCCCGGCGCCGGGCAGGTGCTGCTGCGCACGGTATGGCTGTCGCTCGATCCGTACA
TGCGCGGCCGGATGAGCGACGCGCCGTCGTATGCGCCGCCCGTGCAACTCGGCGACGTGATGGTCGGCGGCACGATCAGC
CGCGTCGTGGCGTCGAACCTGCCGGCGTTCCGCGAGGGCGACCTCGTCGTCGCGGCGGGCGGCTGGCAGGACTATGCGCT
GTCCGACGGCAGCGACCTGATTCCGCTCGGCCGCGATTTTCCGCATCCGTCGCGCGCGCTCGGCGTGCTCGGCATGCCCG
GATTCACGGCGTATACGGGGCTGCTCACGATCGGCGAGCCGAAGGCCGGTGAAACGGTCGTCGTCGCGGCCGCAAGCGGT
GCGGTCGGCGCGGTCGTCGGGCAGATCGCGAAGCTGAAGGGCTGTCGCGTGATCGGCGTCGCGGGCGGCGCCGACAAATG
CGCGTACGTGACCGGCACGCTCGGATTCGACGCATGCATCGACCATCGCGATCCCGCCTTCGCGAGCCAGCTGAAGGCCG
CCTGCCCGAACGGGATCGACGTGTACTTCGAGAACGTCGGCGGCGCCGTATTCGACGCGGTCTGGCCGCTGCTCAACAAT
CACGCGCGCGTGCCGGTATGCGGGCTGATCGCGCATTACAACGACACCGCGCTGCCGGCCGGCCCCGATCGTCTGCCGAA
GCTGATGACGACGATCCTGAGCAAGCGCATCCGCATGCAGGGTTTCATCATCCTCGATTACTATGCGACCGGCTATGCGC
CGTTCCTGAAGGACATGAGCGAATGGGTCGCGCAGGGCAGCGTGAAGGTGCTCGAGGACGTGATCCCCGACCTGACCGAC
GCGCCGGCCGCACTGATCGGCCTGCTCGCCGGCAAGAATTTCGGCAAGGTCGTCGTGCGCGTCGGCCCCGACGAACTCGC
GTAA

Upstream 100 bases:

>100_bases
CGGGGCGATCGGCAGCGCATCGCGGATCGCGCGTAGTCCGCTCGTCCTTTCCTGATTCGATCGTGTGCGTGCACACGCAT
CCTTGTTGACGGAGGCTCAC

Downstream 100 bases:

>100_bases
CCGTTCCACGCATCCGCGGACCGGCGCCGGAAGACGTCGGCCCGCTACGTTGTCGATCGCTTTTTCAAAGGAGAAATCAT
GGCGCTCTACGTGATGGCCT

Product: putative NADP-dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSQSKTANRRIVLNSRPVGAPTANDFRLETGDVPTPGAGQVLLRTVWLSLDPYMRGRMSDAPSYAPPVQLGDVMVGGTIS
RVVASNLPAFREGDLVVAAGGWQDYALSDGSDLIPLGRDFPHPSRALGVLGMPGFTAYTGLLTIGEPKAGETVVVAAASG
AVGAVVGQIAKLKGCRVIGVAGGADKCAYVTGTLGFDACIDHRDPAFASQLKAACPNGIDVYFENVGGAVFDAVWPLLNN
HARVPVCGLIAHYNDTALPAGPDRLPKLMTTILSKRIRMQGFIILDYYATGYAPFLKDMSEWVAQGSVKVLEDVIPDLTD
APAALIGLLAGKNFGKVVVRVGPDELA

Sequences:

>Translated_347_residues
MSQSKTANRRIVLNSRPVGAPTANDFRLETGDVPTPGAGQVLLRTVWLSLDPYMRGRMSDAPSYAPPVQLGDVMVGGTIS
RVVASNLPAFREGDLVVAAGGWQDYALSDGSDLIPLGRDFPHPSRALGVLGMPGFTAYTGLLTIGEPKAGETVVVAAASG
AVGAVVGQIAKLKGCRVIGVAGGADKCAYVTGTLGFDACIDHRDPAFASQLKAACPNGIDVYFENVGGAVFDAVWPLLNN
HARVPVCGLIAHYNDTALPAGPDRLPKLMTTILSKRIRMQGFIILDYYATGYAPFLKDMSEWVAQGSVKVLEDVIPDLTD
APAALIGLLAGKNFGKVVVRVGPDELA
>Mature_346_residues
SQSKTANRRIVLNSRPVGAPTANDFRLETGDVPTPGAGQVLLRTVWLSLDPYMRGRMSDAPSYAPPVQLGDVMVGGTISR
VVASNLPAFREGDLVVAAGGWQDYALSDGSDLIPLGRDFPHPSRALGVLGMPGFTAYTGLLTIGEPKAGETVVVAAASGA
VGAVVGQIAKLKGCRVIGVAGGADKCAYVTGTLGFDACIDHRDPAFASQLKAACPNGIDVYFENVGGAVFDAVWPLLNNH
ARVPVCGLIAHYNDTALPAGPDRLPKLMTTILSKRIRMQGFIILDYYATGYAPFLKDMSEWVAQGSVKVLEDVIPDLTDA
PAALIGLLAGKNFGKVVVRVGPDELA

Specific function: Unknown

COG id: COG2130

COG function: function code R; Putative NADP-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADP-dependent oxidoreductase L4BD family [H]

Homologues:

Organism=Homo sapiens, GI226059159, Length=332, Percent_Identity=39.1566265060241, Blast_Score=238, Evalue=9e-63,
Organism=Homo sapiens, GI226059133, Length=332, Percent_Identity=39.1566265060241, Blast_Score=238, Evalue=9e-63,
Organism=Homo sapiens, GI226246682, Length=347, Percent_Identity=37.1757925072046, Blast_Score=220, Evalue=1e-57,
Organism=Homo sapiens, GI226246680, Length=347, Percent_Identity=37.1757925072046, Blast_Score=220, Evalue=1e-57,
Organism=Homo sapiens, GI22748929, Length=347, Percent_Identity=37.1757925072046, Blast_Score=220, Evalue=1e-57,
Organism=Homo sapiens, GI226056130, Length=305, Percent_Identity=39.0163934426229, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI28557745, Length=326, Percent_Identity=30.3680981595092, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI194239674, Length=229, Percent_Identity=30.5676855895196, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI13236495, Length=229, Percent_Identity=30.5676855895196, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI194239676, Length=198, Percent_Identity=30.8080808080808, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI226510941, Length=345, Percent_Identity=63.1884057971015, Blast_Score=448, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI133901710, Length=355, Percent_Identity=34.0845070422535, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI133901712, Length=355, Percent_Identity=34.0845070422535, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17507255, Length=261, Percent_Identity=27.2030651340996, Blast_Score=72, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6323504, Length=328, Percent_Identity=31.0975609756098, Blast_Score=121, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00107 ADH_zinc_N [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36359; Mature: 36228

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSKTANRRIVLNSRPVGAPTANDFRLETGDVPTPGAGQVLLRTVWLSLDPYMRGRMSD
CCCCCCCCCEEEEECCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCHHHHCCCCC
APSYAPPVQLGDVMVGGTISRVVASNLPAFREGDLVVAAGGWQDYALSDGSDLIPLGRDF
CCCCCCCCCCCCEEECCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
PHPSRALGVLGMPGFTAYTGLLTIGEPKAGETVVVAAASGAVGAVVGQIAKLKGCRVIGV
CCHHHHEEECCCCCHHHHHCEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEE
AGGADKCAYVTGTLGFDACIDHRDPAFASQLKAACPNGIDVYFENVGGAVFDAVWPLLNN
CCCCCCEEEEEECCCHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCC
HARVPVCGLIAHYNDTALPAGPDRLPKLMTTILSKRIRMQGFIILDYYATGYAPFLKDMS
CCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHH
EWVAQGSVKVLEDVIPDLTDAPAALIGLLAGKNFGKVVVRVGPDELA
HHHHCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
SQSKTANRRIVLNSRPVGAPTANDFRLETGDVPTPGAGQVLLRTVWLSLDPYMRGRMSD
CCCCCCCCEEEEECCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCHHHHCCCCC
APSYAPPVQLGDVMVGGTISRVVASNLPAFREGDLVVAAGGWQDYALSDGSDLIPLGRDF
CCCCCCCCCCCCEEECCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
PHPSRALGVLGMPGFTAYTGLLTIGEPKAGETVVVAAASGAVGAVVGQIAKLKGCRVIGV
CCHHHHEEECCCCCHHHHHCEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEE
AGGADKCAYVTGTLGFDACIDHRDPAFASQLKAACPNGIDVYFENVGGAVFDAVWPLLNN
CCCCCCEEEEEECCCHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCC
HARVPVCGLIAHYNDTALPAGPDRLPKLMTTILSKRIRMQGFIILDYYATGYAPFLKDMS
CCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHH
EWVAQGSVKVLEDVIPDLTDAPAALIGLLAGKNFGKVVVRVGPDELA
HHHHCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]