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The map label for this gene is murA [H]

Identifier: 189353043

GI number: 189353043

Start: 1209519

End: 1210820

Strand: Reverse

Name: murA [H]

Synonym: BMULJ_04277

Alternate gene names: 189353043

Gene position: 1210820-1209519 (Counterclockwise)

Preceding gene: 189353045

Following gene: 189353040

Centisome position: 48.96

GC content: 67.13

Gene sequence:

>1302_bases
ATGTCGAATCTCATCGTCCACGGCGGCACCCCGCTGCGCGGGGACATCAAGCCGTCCGCGAACAAGAACGCCGTCCTGCC
GATCCTCTGCGCGACCCTGCTGACCGACCAGCCGCTGCGGCTGATCGGCGTGCCGGACATCACCGACGTGCGCAAGATCC
TCGATATCTTCCGCACGCTCGGCAGCGACGTGTCGGTCGATTTCACGACCGGCCTGCTCGAACTCCATCACCGCAATACG
ACCTTCGACCCGGCCGTCCATCGCCTGCCCGAGGCGATGCGCTCGTCGATCATGCTGATTCCGCCGCTGCTCGCGCGCTT
CGGCGTCGCGCGGCTCGAGAACGACGTGAAAGGCTGCACGCTCGGCGTACGCGAAATCGATCCGCACGTCGAGGTGTTCG
AGCGCTTCGGCGCGCACATCGAGCGCACGTCCGATTCGCTGATCGTCCGCGCCGACGGCCCGCTGACGGCCAACGATCAC
TGGCTCGACTATGCGTCCGTGACGACCACCGAAAACTTCGCGCTGTGCGCGACGGCGGCAAACGGCACGTCGACGCTGAT
GAACGCGGCGTCCGAGCCGCACGTGCAGGAGTTCTGCCAGTTCCTCGCGATGATCGGCGTCGCGGTCGAGGGCATCGGCA
CGTCGCGGCTCTGCGTGACGGGCGGCAGCAAGCTCGGCGGCGGCGAGTTCCGCTTCGCCGAGGATTTCCACGAGATCGCA
ACGTTCCTCGCGCTCGGCGCGATCACCGGCGGCGACATCACCGTGCGTAACTCGTCGCCCGAGCACTTTCCGCTGATCGA
CCGCACATTCGCGAAGTTCGGCGTTCAGGTCACGCACCGCGACGGCTGGTCGCGCGCCGAGCGCGACGGCCCGCTGCGCG
TGCGCCGGCCGTTCACGCAGAACATCCTCACCAAGGTCGAAGCGGCGCCGTGGCCGTACCTGCCGGTCGATCTGCTGCCG
ATCTTCATCGCGCTCGGCGTGCGCGCCGAAGGCAGCGCGATGTTCTGGAACAAGGTCTACGACGGCGCGCTCGGCTGGTC
CGGCGAGTTGTCGAAGTTCGGCGCGCACGTGTTGCTGTCGGATCCGCACCGGCTGATCACGTTCGGCGGGCTGCAACTGA
CGCCGGCGCGTGTCGAAAGCCCGTACATCATCCGCGTCGCGATTGCACTGCTGATGGTCGCCGCGAGCATCGAAGGCCGC
TCCGAAATCATGAACGCGCTGCCGATCCGGCGCGCGCATCCGCGTTTCGTCGAGAACCTGCGCTCGGTCGGCGCGAATGT
GGAGTGGACGAGCAGCGAGTAA

Upstream 100 bases:

>100_bases
GCCGGCGTGCAAGCCGACTTGTCGCATCGAACCCTCCACGCCCTGCGCCGACCAATGGCATCATATGGGCCTACGTCAGC
CACCGATACGCCCCCATATC

Downstream 100 bases:

>100_bases
TGCAATGCAGGATGCGGCGCGCATGAGGTTCGTGCCGCATCCGGTTGTCACGTTCGATCGGCCGCGGTGACGTGGCCCTT
CATGCCTGCGATGGCGGGTC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MSNLIVHGGTPLRGDIKPSANKNAVLPILCATLLTDQPLRLIGVPDITDVRKILDIFRTLGSDVSVDFTTGLLELHHRNT
TFDPAVHRLPEAMRSSIMLIPPLLARFGVARLENDVKGCTLGVREIDPHVEVFERFGAHIERTSDSLIVRADGPLTANDH
WLDYASVTTTENFALCATAANGTSTLMNAASEPHVQEFCQFLAMIGVAVEGIGTSRLCVTGGSKLGGGEFRFAEDFHEIA
TFLALGAITGGDITVRNSSPEHFPLIDRTFAKFGVQVTHRDGWSRAERDGPLRVRRPFTQNILTKVEAAPWPYLPVDLLP
IFIALGVRAEGSAMFWNKVYDGALGWSGELSKFGAHVLLSDPHRLITFGGLQLTPARVESPYIIRVAIALLMVAASIEGR
SEIMNALPIRRAHPRFVENLRSVGANVEWTSSE

Sequences:

>Translated_433_residues
MSNLIVHGGTPLRGDIKPSANKNAVLPILCATLLTDQPLRLIGVPDITDVRKILDIFRTLGSDVSVDFTTGLLELHHRNT
TFDPAVHRLPEAMRSSIMLIPPLLARFGVARLENDVKGCTLGVREIDPHVEVFERFGAHIERTSDSLIVRADGPLTANDH
WLDYASVTTTENFALCATAANGTSTLMNAASEPHVQEFCQFLAMIGVAVEGIGTSRLCVTGGSKLGGGEFRFAEDFHEIA
TFLALGAITGGDITVRNSSPEHFPLIDRTFAKFGVQVTHRDGWSRAERDGPLRVRRPFTQNILTKVEAAPWPYLPVDLLP
IFIALGVRAEGSAMFWNKVYDGALGWSGELSKFGAHVLLSDPHRLITFGGLQLTPARVESPYIIRVAIALLMVAASIEGR
SEIMNALPIRRAHPRFVENLRSVGANVEWTSSE
>Mature_432_residues
SNLIVHGGTPLRGDIKPSANKNAVLPILCATLLTDQPLRLIGVPDITDVRKILDIFRTLGSDVSVDFTTGLLELHHRNTT
FDPAVHRLPEAMRSSIMLIPPLLARFGVARLENDVKGCTLGVREIDPHVEVFERFGAHIERTSDSLIVRADGPLTANDHW
LDYASVTTTENFALCATAANGTSTLMNAASEPHVQEFCQFLAMIGVAVEGIGTSRLCVTGGSKLGGGEFRFAEDFHEIAT
FLALGAITGGDITVRNSSPEHFPLIDRTFAKFGVQVTHRDGWSRAERDGPLRVRRPFTQNILTKVEAAPWPYLPVDLLPI
FIALGVRAEGSAMFWNKVYDGALGWSGELSKFGAHVLLSDPHRLITFGGLQLTPARVESPYIIRVAIALLMVAASIEGRS
EIMNALPIRRAHPRFVENLRSVGANVEWTSSE

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=433, Percent_Identity=31.1778290993072, Blast_Score=202, Evalue=4e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 47284; Mature: 47153

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLIVHGGTPLRGDIKPSANKNAVLPILCATLLTDQPLRLIGVPDITDVRKILDIFRTL
CCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHH
GSDVSVDFTTGLLELHHRNTTFDPAVHRLPEAMRSSIMLIPPLLARFGVARLENDVKGCT
CCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHCCCCCCE
LGVREIDPHVEVFERFGAHIERTSDSLIVRADGPLTANDHWLDYASVTTTENFALCATAA
EEHHHCCHHHHHHHHHCCCEECCCCCEEEEECCCCCCCCCEEEEEEEECCCCEEEEEECC
NGTSTLMNAASEPHVQEFCQFLAMIGVAVEGIGTSRLCVTGGSKLGGGEFRFAEDFHEIA
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHH
TFLALGAITGGDITVRNSSPEHFPLIDRTFAKFGVQVTHRDGWSRAERDGPLRVRRPFTQ
HHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHCEEEEECCCCCCCCCCCCEEEECCHHH
NILTKVEAAPWPYLPVDLLPIFIALGVRAEGSAMFWNKVYDGALGWSGELSKFGAHVLLS
HHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEHHHHHCCCCCCCCCHHHCCCEEEEC
DPHRLITFGGLQLTPARVESPYIIRVAIALLMVAASIEGRSEIMNALPIRRAHPRFVENL
CCCEEEEECCEEECHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHH
RSVGANVEWTSSE
HHCCCCCEECCCC
>Mature Secondary Structure 
SNLIVHGGTPLRGDIKPSANKNAVLPILCATLLTDQPLRLIGVPDITDVRKILDIFRTL
CCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHH
GSDVSVDFTTGLLELHHRNTTFDPAVHRLPEAMRSSIMLIPPLLARFGVARLENDVKGCT
CCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHCCCCCCE
LGVREIDPHVEVFERFGAHIERTSDSLIVRADGPLTANDHWLDYASVTTTENFALCATAA
EEHHHCCHHHHHHHHHCCCEECCCCCEEEEECCCCCCCCCEEEEEEEECCCCEEEEEECC
NGTSTLMNAASEPHVQEFCQFLAMIGVAVEGIGTSRLCVTGGSKLGGGEFRFAEDFHEIA
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHH
TFLALGAITGGDITVRNSSPEHFPLIDRTFAKFGVQVTHRDGWSRAERDGPLRVRRPFTQ
HHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHCEEEEECCCCCCCCCCCCEEEECCHHH
NILTKVEAAPWPYLPVDLLPIFIALGVRAEGSAMFWNKVYDGALGWSGELSKFGAHVLLS
HHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEHHHHHCCCCCCCCCHHHCCCEEEEC
DPHRLITFGGLQLTPARVESPYIIRVAIALLMVAASIEGRSEIMNALPIRRAHPRFVENL
CCCEEEEECCEEECHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHH
RSVGANVEWTSSE
HHCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]