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The map label for this gene is crp [C]

Identifier: 189352961

GI number: 189352961

Start: 1119462

End: 1120205

Strand: Reverse

Name: crp [C]

Synonym: BMULJ_04195

Alternate gene names: 189352961

Gene position: 1120205-1119462 (Counterclockwise)

Preceding gene: 189352963

Following gene: 189352960

Centisome position: 45.29

GC content: 69.49

Gene sequence:

>744_bases
ATGCACGACGCATCCGACGCCTGCCTCCGCACCGCGGATCTCCCCACGGAAACGGGCCCGCTGCCGCCGCTGTCGGCGCT
GTTCGGCGCCTGCGCATGGTTTCGTGCGCTGGCGCCGGCCGATCAGGCGCGCGTGCTCGCGCACTCGCGCGCCGAGCGTC
ACGACGCGGGCAGCGTGATCGCGCAGCGGCTCGCGCCGTCCGAATACTGGATCGGCGTGCACCGCGGGCTGCTGAAGCTC
GCGATCTTCAACGCGTCGGGGCGCGGCTGCACGTTTTCCGGCGTACCGTCCGGCGGCTGGTTCGGCGAAGGCAGCGTGAT
CAAGCGCGAGCCGCGCAAGTACGAGGTCGTCGCGATCCAGCGCTCGACCGTGCTGTTCGTGCCGGCCGACACGTTCCACG
CGCTGCTCGACAGCAGCCTGCCGTTTACGCGCTTCGTGATTCATCAGCTCAACAACCGGATGGGCGAATTCATCGCGTCG
ATCCAGAACAGCCGGCTGCTCGACGTCGACGCGCGCGTCGCGCAAGCGCTCGCGCAGCTGTTCAACCCCGATCTGTATCC
CGACACCGGCCGCTCGCTCGCGATCTCGCAGGAGGAGCTCGGGATGCTCGTCGGCGTGTCGCGGCAGCGGATCAACCAGG
CGCTGCAGCAGCTCGAACGGCGCGGCGTGCTGCGGCTCGCGTACAACCAGATCGACGTCGTCGATCCGGCCGCGCTCGCG
CGGGTCGGCCTCGAACAGATCTGA

Upstream 100 bases:

>100_bases
CCGACAGCCTAACGGGCGCTATTGTGAGCCGTCTGTCATCGAAACGACAGAGTGCCGACCGGGCGCCTCGCGTTATCCCT
ATCCTCGCAAACCCGCATTC

Downstream 100 bases:

>100_bases
CCGTGCACGCGACCGACGCCGGCCGGCGCATCGCGCGCGAAACTGACGGACCCGCCAGTTTCGCGCCAGCAAACCGTCGC
GCGTGCCCCCTATCATTCGG

Product: Crp/Fnr family transcriptional regulator

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Crp Family Transcriptional Regulator; Regulatory Protein; Transcription Regulator Protein; Crp/Fnr Family Transcriptional Regulator; Cyclic-Nucleotide-Gated Cation Channel; CNMP Regulatory Protein; HTH Crp Family Transcriptional Regulator; CAMP-Dependent Transcriptional Regulator; Transcriptional Regulator Crp Family

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MHDASDACLRTADLPTETGPLPPLSALFGACAWFRALAPADQARVLAHSRAERHDAGSVIAQRLAPSEYWIGVHRGLLKL
AIFNASGRGCTFSGVPSGGWFGEGSVIKREPRKYEVVAIQRSTVLFVPADTFHALLDSSLPFTRFVIHQLNNRMGEFIAS
IQNSRLLDVDARVAQALAQLFNPDLYPDTGRSLAISQEELGMLVGVSRQRINQALQQLERRGVLRLAYNQIDVVDPAALA
RVGLEQI

Sequences:

>Translated_247_residues
MHDASDACLRTADLPTETGPLPPLSALFGACAWFRALAPADQARVLAHSRAERHDAGSVIAQRLAPSEYWIGVHRGLLKL
AIFNASGRGCTFSGVPSGGWFGEGSVIKREPRKYEVVAIQRSTVLFVPADTFHALLDSSLPFTRFVIHQLNNRMGEFIAS
IQNSRLLDVDARVAQALAQLFNPDLYPDTGRSLAISQEELGMLVGVSRQRINQALQQLERRGVLRLAYNQIDVVDPAALA
RVGLEQI
>Mature_247_residues
MHDASDACLRTADLPTETGPLPPLSALFGACAWFRALAPADQARVLAHSRAERHDAGSVIAQRLAPSEYWIGVHRGLLKL
AIFNASGRGCTFSGVPSGGWFGEGSVIKREPRKYEVVAIQRSTVLFVPADTFHALLDSSLPFTRFVIHQLNNRMGEFIAS
IQNSRLLDVDARVAQALAQLFNPDLYPDTGRSLAISQEELGMLVGVSRQRINQALQQLERRGVLRLAYNQIDVVDPAALA
RVGLEQI

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 27023; Mature: 27023

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDASDACLRTADLPTETGPLPPLSALFGACAWFRALAPADQARVLAHSRAERHDAGSVI
CCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AQRLAPSEYWIGVHRGLLKLAIFNASGRGCTFSGVPSGGWFGEGSVIKREPRKYEVVAIQ
HHHHCCCHHHHHHHHHHHHHEEECCCCCCCEECCCCCCCCCCCCCCCCCCCCEEEEEEEE
RSTVLFVPADTFHALLDSSLPFTRFVIHQLNNRMGEFIASIQNSRLLDVDARVAQALAQL
CCEEEEEECHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHH
FNPDLYPDTGRSLAISQEELGMLVGVSRQRINQALQQLERRGVLRLAYNQIDVVDPAALA
HCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHCCCCCCCHHHHH
RVGLEQI
HHHHHCC
>Mature Secondary Structure
MHDASDACLRTADLPTETGPLPPLSALFGACAWFRALAPADQARVLAHSRAERHDAGSVI
CCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AQRLAPSEYWIGVHRGLLKLAIFNASGRGCTFSGVPSGGWFGEGSVIKREPRKYEVVAIQ
HHHHCCCHHHHHHHHHHHHHEEECCCCCCCEECCCCCCCCCCCCCCCCCCCCEEEEEEEE
RSTVLFVPADTFHALLDSSLPFTRFVIHQLNNRMGEFIASIQNSRLLDVDARVAQALAQL
CCEEEEEECHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHH
FNPDLYPDTGRSLAISQEELGMLVGVSRQRINQALQQLERRGVLRLAYNQIDVVDPAALA
HCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHCCCCCCCHHHHH
RVGLEQI
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA