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The map label for this gene is creB [H]

Identifier: 189352913

GI number: 189352913

Start: 1059949

End: 1060638

Strand: Reverse

Name: creB [H]

Synonym: BMULJ_04147

Alternate gene names: 189352913

Gene position: 1060638-1059949 (Counterclockwise)

Preceding gene: 189352914

Following gene: 189352912

Centisome position: 42.89

GC content: 66.52

Gene sequence:

>690_bases
ATGAACCCTTTGATCCTCATTGCCGACGACGAGCCGGACATCGTCGAGATCCTCGACGCTTATCTCGCTCATGACGGCTT
CCGCACACGCTGCGTCGATACCGGCCAGGCCGTGCTCGACGCGCATGCCGCACTGAAACCCGACCTGATCCTGCTCGATA
TCCGCATGCCGCAGAAGGACGGCTGGCAGGCGCTGCGCGAACTGCGCCGCCGCGGCAACACGCCGGTCGTGCTGCTGACC
GCGCTCGACCGCGAGATCGATCGCTTGCAGGGGCTGCGCTTCGGCGCCGACGACTACATCACGAAGCCGTTCAACCCGGC
CGAGGTGGTGGCGCGCATCCGCACGATTCTGCGCCGGCTGGACGCGGTTACACCCGGACGCGTCACCACGGTCGGCAACC
TCGAAATCGACGCGGACAGCTATCTGGTCAGCGTTCGCACCGAGTCGGGAGAAACCGGCGTCGCACTGACGCTGACCGAA
TTCCGGCTGCTCGCGCACCTGGCCGGCTCGCCGAACCGTGTCTTTACGCGCGGCGAACTCGTCGATGCGTGCCTGATGGA
CGCCGACGCGCTGGAGCGCACGGTCGACAGTCATATCAGCCGACTGCGCAGAAAGCTCCAGTGCGCGGGCGCTTCGGCCA
TGCCGGAAGTCATGCGCGGCGTCGGCTATCGATTGCGCGGCGCCCGGTAA

Upstream 100 bases:

>100_bases
GGCTGAGCGGCGGGCGGTCGCCGTCGCGCAGTCGCTGCGACGCGCCGGCGGCGACCGCCCGGGATCCGCTTTCCTGCCGT
CTCCCCTTCGAGTGATTCCG

Downstream 100 bases:

>100_bases
CGGCTCGCGACGACGCGTTGCCGCGCGTCGCGCGCGCCGTCGGCTTTCGCGCCGATCCTCGCAGTGCCGTCGCCGTGCGC
ACGGCGCGCGAACCCTTCCC

Product: two-component system catabolic regulation response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MNPLILIADDEPDIVEILDAYLAHDGFRTRCVDTGQAVLDAHAALKPDLILLDIRMPQKDGWQALRELRRRGNTPVVLLT
ALDREIDRLQGLRFGADDYITKPFNPAEVVARIRTILRRLDAVTPGRVTTVGNLEIDADSYLVSVRTESGETGVALTLTE
FRLLAHLAGSPNRVFTRGELVDACLMDADALERTVDSHISRLRRKLQCAGASAMPEVMRGVGYRLRGAR

Sequences:

>Translated_229_residues
MNPLILIADDEPDIVEILDAYLAHDGFRTRCVDTGQAVLDAHAALKPDLILLDIRMPQKDGWQALRELRRRGNTPVVLLT
ALDREIDRLQGLRFGADDYITKPFNPAEVVARIRTILRRLDAVTPGRVTTVGNLEIDADSYLVSVRTESGETGVALTLTE
FRLLAHLAGSPNRVFTRGELVDACLMDADALERTVDSHISRLRRKLQCAGASAMPEVMRGVGYRLRGAR
>Mature_229_residues
MNPLILIADDEPDIVEILDAYLAHDGFRTRCVDTGQAVLDAHAALKPDLILLDIRMPQKDGWQALRELRRRGNTPVVLLT
ALDREIDRLQGLRFGADDYITKPFNPAEVVARIRTILRRLDAVTPGRVTTVGNLEIDADSYLVSVRTESGETGVALTLTE
FRLLAHLAGSPNRVFTRGELVDACLMDADALERTVDSHISRLRRKLQCAGASAMPEVMRGVGYRLRGAR

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=40.0881057268723, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=42.3580786026201, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=38.2222222222222, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=33.7662337662338, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=35.1111111111111, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=35.4260089686099, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=31.6239316239316, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=37.5545851528384, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=34.8214285714286, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1787229, Length=209, Percent_Identity=32.5358851674641, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=32.1428571428571, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=32.2033898305085, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=42.4528301886792, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787375, Length=216, Percent_Identity=28.7037037037037, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=32.3008849557522, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1790299, Length=218, Percent_Identity=27.5229357798165, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787487, Length=100, Percent_Identity=34, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25381; Mature: 25381

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPLILIADDEPDIVEILDAYLAHDGFRTRCVDTGQAVLDAHAALKPDLILLDIRMPQKD
CCCEEEEECCCCHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCC
GWQALRELRRRGNTPVVLLTALDREIDRLQGLRFGADDYITKPFNPAEVVARIRTILRRL
HHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
DAVTPGRVTTVGNLEIDADSYLVSVRTESGETGVALTLTEFRLLAHLAGSPNRVFTRGEL
CCCCCCCEEEEECEEECCCCEEEEEEECCCCCCEEEHHHHHHHHHHHCCCCCCEEEHHHH
VDACLMDADALERTVDSHISRLRRKLQCAGASAMPEVMRGVGYRLRGAR
HHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNPLILIADDEPDIVEILDAYLAHDGFRTRCVDTGQAVLDAHAALKPDLILLDIRMPQKD
CCCEEEEECCCCHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCC
GWQALRELRRRGNTPVVLLTALDREIDRLQGLRFGADDYITKPFNPAEVVARIRTILRRL
HHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
DAVTPGRVTTVGNLEIDADSYLVSVRTESGETGVALTLTEFRLLAHLAGSPNRVFTRGEL
CCCCCCCEEEEECEEECCCCEEEEEEECCCCCCEEEHHHHHHHHHHHCCCCCCEEEHHHH
VDACLMDADALERTVDSHISRLRRKLQCAGASAMPEVMRGVGYRLRGAR
HHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]