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The map label for this gene is ftsI [H]

Identifier: 189352894

GI number: 189352894

Start: 1040661

End: 1042517

Strand: Reverse

Name: ftsI [H]

Synonym: BMULJ_04128

Alternate gene names: 189352894

Gene position: 1042517-1040661 (Counterclockwise)

Preceding gene: 189352895

Following gene: 189352888

Centisome position: 42.15

GC content: 67.85

Gene sequence:

>1857_bases
ATGAGCGCGAAGAAAAAGCCCCACCCCGTCGACCCGTACGCGTCCGCGACCAAGAATCCGATGCTCGCGTCGCGCCTGCC
GATGTGGCGCTCGAAGCTTGTCGTGATTCTCGTGTTCATCGCCTTCGCCGCGCTGATCGTGCGCGCGTTCTGGGTGCAGG
TCGCGAATCAGGATTTCTACGTGGGTCAGGGCCAGAAGCGCTACCAGCGCACGATCGAGCTCGACGCGATGCGCGGGCGC
ATCGTCGACCGCAATGGCGCGATGCTCGCGGTCAGCCTCGCGACCTACGAGATCTGGGCGAACCCGAAGCAGGTGTCCGA
CACCGACTATCCGCAAATCGCGAAGCTGCTCGACATGCCGCTCGCCGAAGTGAAGCGCCGGCTCGGCAACGACAAGACCT
TCGTGCTGCTCAAGCGCCAGGTCGACGCCGAGACCGCAAGCCGCCTCGACAAGCTCGCGATCGACGGCATCACGCAGATC
GCCGATTCGAAGCGCTTCTATCCGGAAGGCGAATCGGCCGCACACGTGGTCGGCTTCACGAACGTCGAGGATCAGGGGCA
GGAAGGCGTCGAGCTCGCCGCGAACGCGCTGCTGTCCGGCACGTCGGGCCAGCGCGAGGTGATTCGCGACCGGCTCGGCC
GGATCGTGTCGGACACGCGGCCGCTCGTGCCCGCGCAGCACGGCGCGACGATCGAGCTGACGATCGACCGGCGCATCCAG
CAGCTCGCGTTCAGCCAGCTGAAGGCCGCCGTGCTCGAGAACAACGCGGTGGCCGGCAGCGTCGTCGTGCTCGATGCGCA
GAACGGCGAAATCCTCGCGCTCGCGAACTATCCGACGTTCGATCCGAACGACCGCGCGCGGCTCACCGGCCAGCAGTTGC
GCAACCGCGCGGTGATCGACACGTTCGAGCCGGGCTCGACGATCAAGCCGCTCGTCGTCGCGCTGTCGATCGACCAGCGC
AAGGTCACGCCGAACACGATCATCAACACGTCGCCGGGCACGTACAAGATCGGCCCGGCCGTGATCCACGACACGTCGAA
CCACGGTTCGCTGACCGTCGCGCAGGCGCTCCAGAAGTCGAGCAACATCGCGCTCGCGAAGCTCGCGCTGAACCTGCCGG
CCGAAACGATCTGGAATAAATATCAGGAATATGGAATCGGCCGCGCGCCGGAGCTCACGTTCCCCGGCGTCGCGTCGGGG
CGGCTGCGCAGCTACCAGCGCTGGCGGCCCATCGAGCAGGCGACGATGGCCTACGGCTACGGGCTCTCGATGTCGCTGCT
GCAGATCGCGCAGATGTACACCGCGTATGCCGGCGACGGCACGCTGCATCCGGTGTCGCTGCTGAAAAACGGCACCGACC
AGCAGACGATCGACGCGCATCGCGGCCATCGCGTGACGTCGCCGCAGACGGCGGCCGCGATCCGTTCGATGCTCGAGATG
GCGGTCGGCGAAGGCGGCACCGGGCGGCGCGCGCGCGTCGACGGCTATCGGATCGGCGGCAAGACCGGTACGGCGCGCAA
GCAGGTCGGCTCGTCGTATGCGAAGGGCAAGTATCGCGCGCTGTTCGCCGGGATGGCGCCGATGAGCAACCCGCGCCTGA
TCGTCGCCGTGATGATCGACGAGCCGCGCGGCAAGGGCTATTACGGCGGCACGGTGGCCGGCCCAGTGTTCGCGTCGGTG
ACGAGCGGCGCGCTGCAACTGCTCGGCGTGCCGCCCGATGCGCCGGTCGAAGCCGATACCGAGACGCCGGCGAGAAAGGC
GCCGCAGAAGACGGTCGCGGTACCGCAGGTCGCGACGCCGGTACGAACGGCCACGCAATCCGGCGACGCGGCGCCGAAAC
GCGCGGCGGCCGGCTGA

Upstream 100 bases:

>100_bases
TCGCACGGCGCACAGTTTCCTCACATGATCTTTACTCATTTATTACAATCCCATTATTCCGACTGACCCGCCGTCTTCCG
GCGACCGACCTGGCCACTGC

Downstream 100 bases:

>100_bases
TTGCGTGAAGAAACGGCGGGCCGCCCGGCCCGCCGTCAATGCGATGCCGCGACCGGCTTCGCCATCCTGCCGAGCACGTG
CTCGGTCATGCCGCGCGCAA

Product: cell division protein

Products: NA

Alternate protein names: PBP-2 [H]

Number of amino acids: Translated: 618; Mature: 617

Protein sequence:

>618_residues
MSAKKKPHPVDPYASATKNPMLASRLPMWRSKLVVILVFIAFAALIVRAFWVQVANQDFYVGQGQKRYQRTIELDAMRGR
IVDRNGAMLAVSLATYEIWANPKQVSDTDYPQIAKLLDMPLAEVKRRLGNDKTFVLLKRQVDAETASRLDKLAIDGITQI
ADSKRFYPEGESAAHVVGFTNVEDQGQEGVELAANALLSGTSGQREVIRDRLGRIVSDTRPLVPAQHGATIELTIDRRIQ
QLAFSQLKAAVLENNAVAGSVVVLDAQNGEILALANYPTFDPNDRARLTGQQLRNRAVIDTFEPGSTIKPLVVALSIDQR
KVTPNTIINTSPGTYKIGPAVIHDTSNHGSLTVAQALQKSSNIALAKLALNLPAETIWNKYQEYGIGRAPELTFPGVASG
RLRSYQRWRPIEQATMAYGYGLSMSLLQIAQMYTAYAGDGTLHPVSLLKNGTDQQTIDAHRGHRVTSPQTAAAIRSMLEM
AVGEGGTGRRARVDGYRIGGKTGTARKQVGSSYAKGKYRALFAGMAPMSNPRLIVAVMIDEPRGKGYYGGTVAGPVFASV
TSGALQLLGVPPDAPVEADTETPARKAPQKTVAVPQVATPVRTATQSGDAAPKRAAAG

Sequences:

>Translated_618_residues
MSAKKKPHPVDPYASATKNPMLASRLPMWRSKLVVILVFIAFAALIVRAFWVQVANQDFYVGQGQKRYQRTIELDAMRGR
IVDRNGAMLAVSLATYEIWANPKQVSDTDYPQIAKLLDMPLAEVKRRLGNDKTFVLLKRQVDAETASRLDKLAIDGITQI
ADSKRFYPEGESAAHVVGFTNVEDQGQEGVELAANALLSGTSGQREVIRDRLGRIVSDTRPLVPAQHGATIELTIDRRIQ
QLAFSQLKAAVLENNAVAGSVVVLDAQNGEILALANYPTFDPNDRARLTGQQLRNRAVIDTFEPGSTIKPLVVALSIDQR
KVTPNTIINTSPGTYKIGPAVIHDTSNHGSLTVAQALQKSSNIALAKLALNLPAETIWNKYQEYGIGRAPELTFPGVASG
RLRSYQRWRPIEQATMAYGYGLSMSLLQIAQMYTAYAGDGTLHPVSLLKNGTDQQTIDAHRGHRVTSPQTAAAIRSMLEM
AVGEGGTGRRARVDGYRIGGKTGTARKQVGSSYAKGKYRALFAGMAPMSNPRLIVAVMIDEPRGKGYYGGTVAGPVFASV
TSGALQLLGVPPDAPVEADTETPARKAPQKTVAVPQVATPVRTATQSGDAAPKRAAAG
>Mature_617_residues
SAKKKPHPVDPYASATKNPMLASRLPMWRSKLVVILVFIAFAALIVRAFWVQVANQDFYVGQGQKRYQRTIELDAMRGRI
VDRNGAMLAVSLATYEIWANPKQVSDTDYPQIAKLLDMPLAEVKRRLGNDKTFVLLKRQVDAETASRLDKLAIDGITQIA
DSKRFYPEGESAAHVVGFTNVEDQGQEGVELAANALLSGTSGQREVIRDRLGRIVSDTRPLVPAQHGATIELTIDRRIQQ
LAFSQLKAAVLENNAVAGSVVVLDAQNGEILALANYPTFDPNDRARLTGQQLRNRAVIDTFEPGSTIKPLVVALSIDQRK
VTPNTIINTSPGTYKIGPAVIHDTSNHGSLTVAQALQKSSNIALAKLALNLPAETIWNKYQEYGIGRAPELTFPGVASGR
LRSYQRWRPIEQATMAYGYGLSMSLLQIAQMYTAYAGDGTLHPVSLLKNGTDQQTIDAHRGHRVTSPQTAAAIRSMLEMA
VGEGGTGRRARVDGYRIGGKTGTARKQVGSSYAKGKYRALFAGMAPMSNPRLIVAVMIDEPRGKGYYGGTVAGPVFASVT
SGALQLLGVPPDAPVEADTETPARKAPQKTVAVPQVATPVRTATQSGDAAPKRAAAG

Specific function: Synthesis of cross-linked peptidoglycan from the lipid intermediates [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=561, Percent_Identity=37.6114081996435, Blast_Score=381, Evalue=1e-107,
Organism=Escherichia coli, GI1786854, Length=609, Percent_Identity=23.6453201970443, Blast_Score=110, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005311
- InterPro:   IPR001460 [H]

Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 66657; Mature: 66526

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKKKPHPVDPYASATKNPMLASRLPMWRSKLVVILVFIAFAALIVRAFWVQVANQDFY
CCCCCCCCCCCCCHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
VGQGQKRYQRTIELDAMRGRIVDRNGAMLAVSLATYEIWANPKQVSDTDYPQIAKLLDMP
ECCCHHHHHHHHHEEHHCCEEEECCCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHCCC
LAEVKRRLGNDKTFVLLKRQVDAETASRLDKLAIDGITQIADSKRFYPEGESAAHVVGFT
HHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEC
NVEDQGQEGVELAANALLSGTSGQREVIRDRLGRIVSDTRPLVPAQHGATIELTIDRRIQ
CCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHH
QLAFSQLKAAVLENNAVAGSVVVLDAQNGEILALANYPTFDPNDRARLTGQQLRNRAVID
HHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCHHCCHHHHCCCCEEE
TFEPGSTIKPLVVALSIDQRKVTPNTIINTSPGTYKIGPAVIHDTSNHGSLTVAQALQKS
ECCCCCCCCEEEEEEECCCCCCCCCCEEECCCCCEEECCEEEEECCCCCCCHHHHHHHCC
SNIALAKLALNLPAETIWNKYQEYGIGRAPELTFPGVASGRLRSYQRWRPIEQATMAYGY
CCEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCC
GLSMSLLQIAQMYTAYAGDGTLHPVSLLKNGTDQQTIDAHRGHRVTSPQTAAAIRSMLEM
CCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHH
AVGEGGTGRRARVDGYRIGGKTGTARKQVGSSYAKGKYRALFAGMAPMSNPRLIVAVMID
HHCCCCCCCCEEECCEEECCCCCHHHHHHCCHHHCCCCEEEEECCCCCCCCCEEEEEEEE
EPRGKGYYGGTVAGPVFASVTSGALQLLGVPPDAPVEADTETPARKAPQKTVAVPQVATP
CCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHCCCHHCCCCCCCCC
VRTATQSGDAAPKRAAAG
HHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SAKKKPHPVDPYASATKNPMLASRLPMWRSKLVVILVFIAFAALIVRAFWVQVANQDFY
CCCCCCCCCCCCHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
VGQGQKRYQRTIELDAMRGRIVDRNGAMLAVSLATYEIWANPKQVSDTDYPQIAKLLDMP
ECCCHHHHHHHHHEEHHCCEEEECCCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHCCC
LAEVKRRLGNDKTFVLLKRQVDAETASRLDKLAIDGITQIADSKRFYPEGESAAHVVGFT
HHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEC
NVEDQGQEGVELAANALLSGTSGQREVIRDRLGRIVSDTRPLVPAQHGATIELTIDRRIQ
CCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHH
QLAFSQLKAAVLENNAVAGSVVVLDAQNGEILALANYPTFDPNDRARLTGQQLRNRAVID
HHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCHHCCHHHHCCCCEEE
TFEPGSTIKPLVVALSIDQRKVTPNTIINTSPGTYKIGPAVIHDTSNHGSLTVAQALQKS
ECCCCCCCCEEEEEEECCCCCCCCCCEEECCCCCEEECCEEEEECCCCCCCHHHHHHHCC
SNIALAKLALNLPAETIWNKYQEYGIGRAPELTFPGVASGRLRSYQRWRPIEQATMAYGY
CCEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCC
GLSMSLLQIAQMYTAYAGDGTLHPVSLLKNGTDQQTIDAHRGHRVTSPQTAAAIRSMLEM
CCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHH
AVGEGGTGRRARVDGYRIGGKTGTARKQVGSSYAKGKYRALFAGMAPMSNPRLIVAVMID
HHCCCCCCCCEEECCEEECCCCCHHHHHHCCHHHCCCCEEEEECCCCCCCCCEEEEEEEE
EPRGKGYYGGTVAGPVFASVTSGALQLLGVPPDAPVEADTETPARKAPQKTVAVPQVATP
CCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHCCCHHCCCCCCCCC
VRTATQSGDAAPKRAAAG
HHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3126399 [H]