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The map label for this gene is dpx [H]

Identifier: 189352887

GI number: 189352887

Start: 1030706

End: 1032472

Strand: Direct

Name: dpx [H]

Synonym: BMULJ_04121

Alternate gene names: 189352887

Gene position: 1030706-1032472 (Clockwise)

Preceding gene: 189352886

Following gene: 189352889

Centisome position: 41.68

GC content: 70.18

Gene sequence:

>1767_bases
ATGCGGATTCACAATGCCGAATGTGCGGCCGTCTTCGCCGAAATCGCGGACATGCTCGAGATTCAGGGCGCGAATCCGTT
CCGGGTCCGCGCGTATCGCAACGTGGCACGCACGATTGCCGACTACGGCCATGACATTCCGTCGATGCTCGCCGACGGCG
GCGAGCTCGTGCGGATCCCGTCGATCGGCCCGGATCTCGCGTCGAAGCTGCGCGAGATTGCGCAGACGGGCACCTGCGAA
TTGCAGCAGACGCTGCGCCGCGCGCTGCCCGGCGCGATCGTTCAGCTGCTCGACGTGCCGGGCCTCGGTGCGAAGCGCGT
GAAGGCGCTGCACGATGCCTTGCGTATCGAAACGCTCGAACAGCTGCGCGTCGAAACCAAGAACGGGCACGTGCGTGCGC
TGCCCGGTTTCGGCGCGAAAACGGAAGCGCAACTGCTCGACGCGCTCGACGAACGCTTGCGCCGCACGCCGCGGCGCTGT
CTGCTGCCGGTCGCGACCGACGTGCTCGCGCCGCTGCTCGAACGGCTGCACGCAGTGCCCGGCGTGATCGAGGCCGTCGC
GGCCGGCAGCGTGCGGCGGCGTCGCGAAACGGTCGGCGATCTCGACATTCTCGTATCGGCGCGCGACGCGGCCGCCGTCG
CCGATGCCTTCACGCGCGGCGACGCGGTCGAACGCGTGCTCGCGAAGGGCAAGACGCGCTCGAGCATCGTGCTCGCGTGC
GGGCTGCAGGTCGACCTGCGCGTCGTCGACGCCGATGCATTCGGTGCGGCGCTCGTCTACTTCACCGGTTCGAAAGCGCA
CAACATCGCGCTGCGCCGGATCGCGCAGGCGGCCGGGCTGAAGATCAACGAGTACGGCGTGTTTCGCGGCGAAGAGCGGA
TCGCCGGTGCGACGGAAGCGTCGGTCTACGACGCGATCGGCCTGCAGTGGGTGCCGCCCGAGCTGCGCGAAGGGCGTGGC
GAGATCGAGGCGGCGCGCGCCGGCATGCTGCCGACGCTCATCGAGCGCAGCGCTCTTCACGGCGATTTCCACGTACATAC
CGACGCATCCGGCGGTCGCGACGGCTTGCACGCGATCGCTGAGGCCGCGCGCTCGCGCGGGCTCAGCTATCTTGCCGTGA
CCGATCGCGCACCCGATGCGGGCCGCGGGCGCACGGCCGATTTCACATGGCTGCTCCGGCAGCTCGACGAGATCGATCGG
CTCAACGCATCGTTCGACGACTTCGTGCTGCTGAAAGGCGTCGAGGCCGGCATTCGTGACGACGGCAGCCTCGACGTGCC
GGCCGATGTGCTCGACCGGCTCGAGATCGTCGTCGGCGCGGTGCGCGACGGCTTCGATCTGCCGCGCGACGCACAGACCG
CGCGGATGCTGCGCGCGATCGACGATCCGCATCTGACGATCGTCGCACATCCGGCCGGCCGCTTGCTCGGCGAGCGCGAC
GGCTGCGACGTCGATCTGCCGCGCGTGATCGCGCATGCAGCGGCGCGCGGCTGCAGCGTCGAACTCGATGCGCAGCCGCA
GCGGCTCGACTTGCCGGACGTCTGGTGCCGCGAGGCCGCGAAGGCCGGCGTGCCGGTCGCGATCGGATCGGATGCGATGA
GCGCGGACGAACTCGGCTATCTCGACGGCGGCGTCGATCAGGCGCGGCGCGGCTGGCTGACGCCGCACGACGTGCTCAAC
ACGCGCACGCTCGCGCAGCTGCGTCCGTTGCTCGCGCGCGCCGCGGACGCAAGCGCGGCGCAGCGCCGCCGCCGCAACGG
CACGTGA

Upstream 100 bases:

>100_bases
AGGAGCGCCCGGCATCGACGCGCCTGCGCGCGCGGGCGGCGCGATGCCGGACGACCGACACCGCGCGGCGTCATCTACGT
GGAAGGGGGCCACGCCGATC

Downstream 100 bases:

>100_bases
ACGCGACCAGTCGACGCGTGCCACGCCGTCGCGCGATCACGCGATCACGCGATCACGCGAGCACGTCGATCGCCGGCACG
TACGGCAGCCGCAGCGCCTG

Product: family X DNA polymerase

Products: NA

Alternate protein names: DNA polymerase type-X; 3'-5' exodeoxyribonuclease; 3'-5' exonuclease [H]

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MRIHNAECAAVFAEIADMLEIQGANPFRVRAYRNVARTIADYGHDIPSMLADGGELVRIPSIGPDLASKLREIAQTGTCE
LQQTLRRALPGAIVQLLDVPGLGAKRVKALHDALRIETLEQLRVETKNGHVRALPGFGAKTEAQLLDALDERLRRTPRRC
LLPVATDVLAPLLERLHAVPGVIEAVAAGSVRRRRETVGDLDILVSARDAAAVADAFTRGDAVERVLAKGKTRSSIVLAC
GLQVDLRVVDADAFGAALVYFTGSKAHNIALRRIAQAAGLKINEYGVFRGEERIAGATEASVYDAIGLQWVPPELREGRG
EIEAARAGMLPTLIERSALHGDFHVHTDASGGRDGLHAIAEAARSRGLSYLAVTDRAPDAGRGRTADFTWLLRQLDEIDR
LNASFDDFVLLKGVEAGIRDDGSLDVPADVLDRLEIVVGAVRDGFDLPRDAQTARMLRAIDDPHLTIVAHPAGRLLGERD
GCDVDLPRVIAHAAARGCSVELDAQPQRLDLPDVWCREAAKAGVPVAIGSDAMSADELGYLDGGVDQARRGWLTPHDVLN
TRTLAQLRPLLARAADASAAQRRRRNGT

Sequences:

>Translated_588_residues
MRIHNAECAAVFAEIADMLEIQGANPFRVRAYRNVARTIADYGHDIPSMLADGGELVRIPSIGPDLASKLREIAQTGTCE
LQQTLRRALPGAIVQLLDVPGLGAKRVKALHDALRIETLEQLRVETKNGHVRALPGFGAKTEAQLLDALDERLRRTPRRC
LLPVATDVLAPLLERLHAVPGVIEAVAAGSVRRRRETVGDLDILVSARDAAAVADAFTRGDAVERVLAKGKTRSSIVLAC
GLQVDLRVVDADAFGAALVYFTGSKAHNIALRRIAQAAGLKINEYGVFRGEERIAGATEASVYDAIGLQWVPPELREGRG
EIEAARAGMLPTLIERSALHGDFHVHTDASGGRDGLHAIAEAARSRGLSYLAVTDRAPDAGRGRTADFTWLLRQLDEIDR
LNASFDDFVLLKGVEAGIRDDGSLDVPADVLDRLEIVVGAVRDGFDLPRDAQTARMLRAIDDPHLTIVAHPAGRLLGERD
GCDVDLPRVIAHAAARGCSVELDAQPQRLDLPDVWCREAAKAGVPVAIGSDAMSADELGYLDGGVDQARRGWLTPHDVLN
TRTLAQLRPLLARAADASAAQRRRRNGT
>Mature_588_residues
MRIHNAECAAVFAEIADMLEIQGANPFRVRAYRNVARTIADYGHDIPSMLADGGELVRIPSIGPDLASKLREIAQTGTCE
LQQTLRRALPGAIVQLLDVPGLGAKRVKALHDALRIETLEQLRVETKNGHVRALPGFGAKTEAQLLDALDERLRRTPRRC
LLPVATDVLAPLLERLHAVPGVIEAVAAGSVRRRRETVGDLDILVSARDAAAVADAFTRGDAVERVLAKGKTRSSIVLAC
GLQVDLRVVDADAFGAALVYFTGSKAHNIALRRIAQAAGLKINEYGVFRGEERIAGATEASVYDAIGLQWVPPELREGRG
EIEAARAGMLPTLIERSALHGDFHVHTDASGGRDGLHAIAEAARSRGLSYLAVTDRAPDAGRGRTADFTWLLRQLDEIDR
LNASFDDFVLLKGVEAGIRDDGSLDVPADVLDRLEIVVGAVRDGFDLPRDAQTARMLRAIDDPHLTIVAHPAGRLLGERD
GCDVDLPRVIAHAAARGCSVELDAQPQRLDLPDVWCREAAKAGVPVAIGSDAMSADELGYLDGGVDQARRGWLTPHDVLN
TRTLAQLRPLLARAADASAAQRRRRNGT

Specific function: Strictly DNA-template-directed DNA polymerase, preferentially acting on DNA structures containing gaps from one to a few nucleotides and bearing a phosphate group at the 5' end of the downstream DNA. The fact that PolX is able to conduct filling of a sing

COG id: COG1796

COG function: function code L; DNA polymerase IV (family X)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the PHP family [H]

Homologues:

Organism=Homo sapiens, GI4505931, Length=345, Percent_Identity=26.0869565217391, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002054
- InterPro:   IPR010996
- InterPro:   IPR003583
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195
- InterPro:   IPR022311 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 63323; Mature: 63323

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIHNAECAAVFAEIADMLEIQGANPFRVRAYRNVARTIADYGHDIPSMLADGGELVRIP
CCCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCHHHHHCCCCCEEECC
SIGPDLASKLREIAQTGTCELQQTLRRALPGAIVQLLDVPGLGAKRVKALHDALRIETLE
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
QLRVETKNGHVRALPGFGAKTEAQLLDALDERLRRTPRRCLLPVATDVLAPLLERLHAVP
HHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCH
GVIEAVAAGSVRRRRETVGDLDILVSARDAAAVADAFTRGDAVERVLAKGKTRSSIVLAC
HHHHHHHHHHHHHHHHHHCCHHEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
GLQVDLRVVDADAFGAALVYFTGSKAHNIALRRIAQAAGLKINEYGVFRGEERIAGATEA
CCEEEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHCCEEECCCCCCCCHHHCCCHHH
SVYDAIGLQWVPPELREGRGEIEAARAGMLPTLIERSALHGDFHVHTDASGGRDGLHAIA
HHHHHCCCEECCHHHHCCCCHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
EAARSRGLSYLAVTDRAPDAGRGRTADFTWLLRQLDEIDRLNASFDDFVLLKGVEAGIRD
HHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCC
DGSLDVPADVLDRLEIVVGAVRDGFDLPRDAQTARMLRAIDDPHLTIVAHPAGRLLGERD
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEEEECCHHHHCCCCC
GCDVDLPRVIAHAAARGCSVELDAQPQRLDLPDVWCREAAKAGVPVAIGSDAMSADELGY
CCCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCHHHCCC
LDGGVDQARRGWLTPHDVLNTRTLAQLRPLLARAADASAAQRRRRNGT
CCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC
>Mature Secondary Structure
MRIHNAECAAVFAEIADMLEIQGANPFRVRAYRNVARTIADYGHDIPSMLADGGELVRIP
CCCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCHHHHHCCCCCEEECC
SIGPDLASKLREIAQTGTCELQQTLRRALPGAIVQLLDVPGLGAKRVKALHDALRIETLE
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
QLRVETKNGHVRALPGFGAKTEAQLLDALDERLRRTPRRCLLPVATDVLAPLLERLHAVP
HHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCH
GVIEAVAAGSVRRRRETVGDLDILVSARDAAAVADAFTRGDAVERVLAKGKTRSSIVLAC
HHHHHHHHHHHHHHHHHHCCHHEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
GLQVDLRVVDADAFGAALVYFTGSKAHNIALRRIAQAAGLKINEYGVFRGEERIAGATEA
CCEEEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHCCEEECCCCCCCCHHHCCCHHH
SVYDAIGLQWVPPELREGRGEIEAARAGMLPTLIERSALHGDFHVHTDASGGRDGLHAIA
HHHHHCCCEECCHHHHCCCCHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
EAARSRGLSYLAVTDRAPDAGRGRTADFTWLLRQLDEIDRLNASFDDFVLLKGVEAGIRD
HHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCC
DGSLDVPADVLDRLEIVVGAVRDGFDLPRDAQTARMLRAIDDPHLTIVAHPAGRLLGERD
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEEEECCHHHHCCCCC
GCDVDLPRVIAHAAARGCSVELDAQPQRLDLPDVWCREAAKAGVPVAIGSDAMSADELGY
CCCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCHHHCCC
LDGGVDQARRGWLTPHDVLNTRTLAQLRPLLARAADASAAQRRRRNGT
CCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]