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The map label for this gene is zraR [H]

Identifier: 189352877

GI number: 189352877

Start: 1018260

End: 1019651

Strand: Direct

Name: zraR [H]

Synonym: BMULJ_04111

Alternate gene names: 189352877

Gene position: 1018260-1019651 (Clockwise)

Preceding gene: 189352874

Following gene: 189352884

Centisome position: 41.17

GC content: 67.46

Gene sequence:

>1392_bases
ATGAATATGCCAATAACGCGCGATAAGAACGCCGGCGGTGAGCGGGACGCGGGACAGCGCCCGCTGATCTACTGGACGCA
AGCGCCATCCGTCATGCTGCGCAAGGAACTGGCGCGCCGCGACTGGAAGGTCTCGATCGTCACGCATGCCAACGAGCTGC
GCGACACCGCCGGCGAGATCACCTGCGGCATCCTCGATCTCAGCGGCGGCCACGCCGACGCGATCGGCAGCATCGCATCG
ACCTGTGCCTCGATGCGCGACGTCGTGTGGGTCGCGCTCGTCGACGCCGGGCAAACCGCCTCGCCGAACGTTCGTGCGTT
ATTGCGCGATTATTGTTTCGACTACATCACGCTGCCGGCCTCGCATCAGCGCATCGCCGATACGGTCGGCCACGCGTACG
GGATGGAGTGCCTGTTCGCGCGCGATCGCGAACGGCTCGAATCGGACGAGCACGGCATCGTCGGCACCTGCAGCGCGATG
CTGCGGCTGTTCGATACCGTGCGGCGTTTCGCGCGCACCGACGCGCCCGTGTTCGTGTTCGGCGAAACGGGAACGGGCAA
GGAGCTGACGGCCGTCGCGATTCACCGTCATTCGGAACGCCGCAACGGCCCGTTCGTCGCGGTCAACTGCGGCGCGATTC
CGCCGCATCTGCTGCAGTCGGAACTGTTCGGCTACGAGCGCGGTGCGTTTACCGGCGCGAACGCGCGCAAGATCGGCTAT
GTCGAGGCCGCGAACGGCGGCACGCTGCTGCTCGACGAAATCGGCGATCTGCCGCACGAGAGTCAGGCGAGCCTGCTGCG
ATTCCTGCAGGAGCGCGCGATTCACCGGCTCGGCGGCAGCGATCCGGTGCCCGTCGACGTGCGGATCGTGTCGGCGACGC
ACGTCGATCTGCGCGACGCGATGGAGGAAGGGCGCTTCCGCGCGGACTTGTTCCATCGGCTCTGCGTGATGCGGATCGAC
CAGCCGCCGCTGCGGGCGCGCGGCAAGGACATCGAGCTGCTCGCGCATCACATGCTCGAACGTTTCCGCGGCGACGCGCG
TCATCGCGTGCGCGGCTTCTCGACCGATGCGATCACGGCGCTGTACAAGCACGACTGGCCCGGCAACGTCCGCGAGCTGA
TCAATCGCGTGCGGCGCGCGGTCGTGATGACCGAAGGGCGGCTCATCACCGCGCGCGATCTCGAGCTCGAATACTGTCTC
GATGCCGCATCGCCGTCGGTCGCCGACATGCGCAAGTGGATCGAGCGCGAGGCGATCGAAACCGCGCTGCTGCGCACGCG
CGGCCGCGTCGCGGCATCCGCGCGCGAACTCGGCGTGTCGCGCGCGACGCTGTATCGGTGGATGGAAGCCTACGGTATCG
AGCGGCCGCGCGGTACCGGATCGTCCGACTGA

Upstream 100 bases:

>100_bases
TTCGCCAAAGCTGCGGAAACGCAGCGCGGACAGGCGCTCATGTGCCGTCGTCCGCAACGCACGCGAACGGTTCCGGGAGT
GGAGAAAGTGACGGTTTGTT

Downstream 100 bases:

>100_bases
CCGACCACCTCCGGCCGCGGCTTGCGCCGCGGACCTTCATCGAACCGATTCGATTCGCGCGGCGCAGCGGTGTACCGGTA
TGCCGCTGCGCCGCTGTGCG

Product: sigma54-dependent DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MNMPITRDKNAGGERDAGQRPLIYWTQAPSVMLRKELARRDWKVSIVTHANELRDTAGEITCGILDLSGGHADAIGSIAS
TCASMRDVVWVALVDAGQTASPNVRALLRDYCFDYITLPASHQRIADTVGHAYGMECLFARDRERLESDEHGIVGTCSAM
LRLFDTVRRFARTDAPVFVFGETGTGKELTAVAIHRHSERRNGPFVAVNCGAIPPHLLQSELFGYERGAFTGANARKIGY
VEAANGGTLLLDEIGDLPHESQASLLRFLQERAIHRLGGSDPVPVDVRIVSATHVDLRDAMEEGRFRADLFHRLCVMRID
QPPLRARGKDIELLAHHMLERFRGDARHRVRGFSTDAITALYKHDWPGNVRELINRVRRAVVMTEGRLITARDLELEYCL
DAASPSVADMRKWIEREAIETALLRTRGRVAASARELGVSRATLYRWMEAYGIERPRGTGSSD

Sequences:

>Translated_463_residues
MNMPITRDKNAGGERDAGQRPLIYWTQAPSVMLRKELARRDWKVSIVTHANELRDTAGEITCGILDLSGGHADAIGSIAS
TCASMRDVVWVALVDAGQTASPNVRALLRDYCFDYITLPASHQRIADTVGHAYGMECLFARDRERLESDEHGIVGTCSAM
LRLFDTVRRFARTDAPVFVFGETGTGKELTAVAIHRHSERRNGPFVAVNCGAIPPHLLQSELFGYERGAFTGANARKIGY
VEAANGGTLLLDEIGDLPHESQASLLRFLQERAIHRLGGSDPVPVDVRIVSATHVDLRDAMEEGRFRADLFHRLCVMRID
QPPLRARGKDIELLAHHMLERFRGDARHRVRGFSTDAITALYKHDWPGNVRELINRVRRAVVMTEGRLITARDLELEYCL
DAASPSVADMRKWIEREAIETALLRTRGRVAASARELGVSRATLYRWMEAYGIERPRGTGSSD
>Mature_463_residues
MNMPITRDKNAGGERDAGQRPLIYWTQAPSVMLRKELARRDWKVSIVTHANELRDTAGEITCGILDLSGGHADAIGSIAS
TCASMRDVVWVALVDAGQTASPNVRALLRDYCFDYITLPASHQRIADTVGHAYGMECLFARDRERLESDEHGIVGTCSAM
LRLFDTVRRFARTDAPVFVFGETGTGKELTAVAIHRHSERRNGPFVAVNCGAIPPHLLQSELFGYERGAFTGANARKIGY
VEAANGGTLLLDEIGDLPHESQASLLRFLQERAIHRLGGSDPVPVDVRIVSATHVDLRDAMEEGRFRADLFHRLCVMRID
QPPLRARGKDIELLAHHMLERFRGDARHRVRGFSTDAITALYKHDWPGNVRELINRVRRAVVMTEGRLITARDLELEYCL
DAASPSVADMRKWIEREAIETALLRTRGRVAASARELGVSRATLYRWMEAYGIERPRGTGSSD

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=385, Percent_Identity=39.2207792207792, Blast_Score=256, Evalue=3e-69,
Organism=Escherichia coli, GI1788905, Length=356, Percent_Identity=39.3258426966292, Blast_Score=251, Evalue=9e-68,
Organism=Escherichia coli, GI1788550, Length=363, Percent_Identity=39.3939393939394, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1790299, Length=388, Percent_Identity=38.4020618556701, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI87082117, Length=318, Percent_Identity=44.3396226415094, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1789233, Length=321, Percent_Identity=43.9252336448598, Blast_Score=238, Evalue=5e-64,
Organism=Escherichia coli, GI1789087, Length=308, Percent_Identity=40.5844155844156, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1786524, Length=325, Percent_Identity=40.6153846153846, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI87082152, Length=317, Percent_Identity=40.6940063091483, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI87081872, Length=231, Percent_Identity=44.1558441558442, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1787583, Length=314, Percent_Identity=34.7133757961783, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI87081858, Length=300, Percent_Identity=33, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789828, Length=266, Percent_Identity=34.2105263157895, Blast_Score=132, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51575; Mature: 51575

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMPITRDKNAGGERDAGQRPLIYWTQAPSVMLRKELARRDWKVSIVTHANELRDTAGEI
CCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCEEEEEECHHHHHHCCCCE
TCGILDLSGGHADAIGSIASTCASMRDVVWVALVDAGQTASPNVRALLRDYCFDYITLPA
EEEEEEECCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHEECCC
SHQRIADTVGHAYGMECLFARDRERLESDEHGIVGTCSAMLRLFDTVRRFARTDAPVFVF
CHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEE
GETGTGKELTAVAIHRHSERRNGPFVAVNCGAIPPHLLQSELFGYERGAFTGANARKIGY
ECCCCCCCEEHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCEEEE
VEAANGGTLLLDEIGDLPHESQASLLRFLQERAIHRLGGSDPVPVDVRIVSATHVDLRDA
EEECCCCEEEHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCHHHHHH
MEEGRFRADLFHRLCVMRIDQPPLRARGKDIELLAHHMLERFRGDARHRVRGFSTDAITA
HHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHH
LYKHDWPGNVRELINRVRRAVVMTEGRLITARDLELEYCLDAASPSVADMRKWIEREAIE
HHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHH
TALLRTRGRVAASARELGVSRATLYRWMEAYGIERPRGTGSSD
HHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNMPITRDKNAGGERDAGQRPLIYWTQAPSVMLRKELARRDWKVSIVTHANELRDTAGEI
CCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCEEEEEECHHHHHHCCCCE
TCGILDLSGGHADAIGSIASTCASMRDVVWVALVDAGQTASPNVRALLRDYCFDYITLPA
EEEEEEECCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHEECCC
SHQRIADTVGHAYGMECLFARDRERLESDEHGIVGTCSAMLRLFDTVRRFARTDAPVFVF
CHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEE
GETGTGKELTAVAIHRHSERRNGPFVAVNCGAIPPHLLQSELFGYERGAFTGANARKIGY
ECCCCCCCEEHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCEEEE
VEAANGGTLLLDEIGDLPHESQASLLRFLQERAIHRLGGSDPVPVDVRIVSATHVDLRDA
EEECCCCEEEHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCHHHHHH
MEEGRFRADLFHRLCVMRIDQPPLRARGKDIELLAHHMLERFRGDARHRVRGFSTDAITA
HHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHH
LYKHDWPGNVRELINRVRRAVVMTEGRLITARDLELEYCLDAASPSVADMRKWIEREAIE
HHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHH
TALLRTRGRVAASARELGVSRATLYRWMEAYGIERPRGTGSSD
HHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]