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The map label for this gene is yecA [H]

Identifier: 189352857

GI number: 189352857

Start: 983602

End: 984876

Strand: Reverse

Name: yecA [H]

Synonym: BMULJ_04091

Alternate gene names: 189352857

Gene position: 984876-983602 (Counterclockwise)

Preceding gene: 189352858

Following gene: 189352855

Centisome position: 39.82

GC content: 73.57

Gene sequence:

>1275_bases
ATGCGCTCGCACGCCGATTCCCCCGCCGCTCATCACGGCGGTTCGCTGACGATTTTCCAGGGCGCCGCGCTCTATATCGG
CGCGGTGCTCGGCACCGGCGTGATCGCGTTGCCCGCCCTGGCCGCCGACGTCGCGGGCCCCGCGTCGCTGCTCGCGTGGG
CCGCGCTCGTCGTGCTGTCGGCGCCGCTCGCGGCGACGTTCGCGGCGCTCGGCGCACGCTACCCGGACGCCGGCGGCGTA
TCGACGTATGCGCGACGCGCGTTCGGGCCGAAGGCGGCCGCCATCGTCGGCTGGTGCTTCTATTTCGCGGTGCCGGCCGG
CGCGCCGGCGGCCGCGATGTTCGGCGGCGCGTACGTCGCGGCCGTGACGGGCGGCGGACAAACGACCGTCATCGCGACCG
CGGCCGCGCTGATCGCGATCGTGTCGGCCGCGAACGCGTTCGGCGTGACGGTGTCGGGCCGCATGCAACTCGTACTGTCA
GCGCTGCTCGTGACGCTGCTGCTCGCGGCCGTGCTCGCGTCCGCGCCGCATGCGCGCACGGCGAACCTGCATCCTTTCGC
GCCGCACGGCTGGCTCGCGGTCGGACAGGCGGCCGCGCTGCTCGTCTGGAGCTTCGCGGGATGGGAAGCGATCACGCATC
TGGCGGCCGAATTTCGACGCCCCGCGCACGACATGCCGCGCTCGGCCGGCATTGCGGTCGTGGTCGTCGGCTTGCTGTAT
CTGTCCGTGGCGGCGGCGAGCGTGATGGTGCTCGGGCCGTCGGCCGGCGCGTCGGGCGCCCCGCTCGCCGAACTGATCGC
CGGCGGTATCGGCGGCCATGCGCAGGTGCTGGCGACGGCCGCGGCGCTGCTGCTCACGCTCGGCACGATGAACGCCTATT
TCGCCGGCGCGGCGAAACTCGGTGCGGCGCTCGGCCGCGACGGCGCGCTGCCCGCGTGGCTCGCGCAAGGCAGTCAGGTC
GGCGGCGTGCCTCGCCGCAGCCTCGGTGCAATTGCGGTGCTCGCGGCGGCCGCGCTCGCCGCGACGACGCTCGCGGGCGT
CGGGCCGACGCCGCTCGTGCTCGTCACGTCGGGCTGCTTCGTGATGGTGTACGGGCTCGGCGCGGCGGCTGCACTGAAAC
TGCTGCCGCGCGGCAGCGTCGCGTATCGCTGCGCGTGGATTTCGCTGATCGCGGTCGCCGGGCTGTTCGTGACGACGGGA
TGGTATGTCGTGTGCCCGTTGCTGCTTGCCGGCGGTGCGCTGCTCTATCTGCGGATGACGGTGCGGCCGGGGTGA

Upstream 100 bases:

>100_bases
ATCGCCGCGCCGCGGCGCCGCTGCCGTTCGGGTAGCATCGGACGATTATTCACCGCGCGGCACGCCGCGCGTACGACAAG
CCGTCCGGAGACAGTCACCC

Downstream 100 bases:

>100_bases
CGCGATGCGCCGTGTGGTCGCGGGTGCGGGTGGCGGCTGCGGGTGGCGGCGTGGCGCTACGCGCTACGCGCTCGGCGTTT
GGCGCTGGGCGGTTGGCGGG

Product: APA family basic amino acid/polyamine antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MRSHADSPAAHHGGSLTIFQGAALYIGAVLGTGVIALPALAADVAGPASLLAWAALVVLSAPLAATFAALGARYPDAGGV
STYARRAFGPKAAAIVGWCFYFAVPAGAPAAAMFGGAYVAAVTGGGQTTVIATAAALIAIVSAANAFGVTVSGRMQLVLS
ALLVTLLLAAVLASAPHARTANLHPFAPHGWLAVGQAAALLVWSFAGWEAITHLAAEFRRPAHDMPRSAGIAVVVVGLLY
LSVAAASVMVLGPSAGASGAPLAELIAGGIGGHAQVLATAAALLLTLGTMNAYFAGAAKLGAALGRDGALPAWLAQGSQV
GGVPRRSLGAIAVLAAAALAATTLAGVGPTPLVLVTSGCFVMVYGLGAAAALKLLPRGSVAYRCAWISLIAVAGLFVTTG
WYVVCPLLLAGGALLYLRMTVRPG

Sequences:

>Translated_424_residues
MRSHADSPAAHHGGSLTIFQGAALYIGAVLGTGVIALPALAADVAGPASLLAWAALVVLSAPLAATFAALGARYPDAGGV
STYARRAFGPKAAAIVGWCFYFAVPAGAPAAAMFGGAYVAAVTGGGQTTVIATAAALIAIVSAANAFGVTVSGRMQLVLS
ALLVTLLLAAVLASAPHARTANLHPFAPHGWLAVGQAAALLVWSFAGWEAITHLAAEFRRPAHDMPRSAGIAVVVVGLLY
LSVAAASVMVLGPSAGASGAPLAELIAGGIGGHAQVLATAAALLLTLGTMNAYFAGAAKLGAALGRDGALPAWLAQGSQV
GGVPRRSLGAIAVLAAAALAATTLAGVGPTPLVLVTSGCFVMVYGLGAAAALKLLPRGSVAYRCAWISLIAVAGLFVTTG
WYVVCPLLLAGGALLYLRMTVRPG
>Mature_424_residues
MRSHADSPAAHHGGSLTIFQGAALYIGAVLGTGVIALPALAADVAGPASLLAWAALVVLSAPLAATFAALGARYPDAGGV
STYARRAFGPKAAAIVGWCFYFAVPAGAPAAAMFGGAYVAAVTGGGQTTVIATAAALIAIVSAANAFGVTVSGRMQLVLS
ALLVTLLLAAVLASAPHARTANLHPFAPHGWLAVGQAAALLVWSFAGWEAITHLAAEFRRPAHDMPRSAGIAVVVVGLLY
LSVAAASVMVLGPSAGASGAPLAELIAGGIGGHAQVLATAAALLLTLGTMNAYFAGAAKLGAALGRDGALPAWLAQGSQV
GGVPRRSLGAIAVLAAAALAATTLAGVGPTPLVLVTSGCFVMVYGLGAAAALKLLPRGSVAYRCAWISLIAVAGLFVTTG
WYVVCPLLLAGGALLYLRMTVRPG

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI187423910, Length=251, Percent_Identity=25.0996015936255, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI7657591, Length=251, Percent_Identity=25.0996015936255, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1790584, Length=363, Percent_Identity=32.5068870523416, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1789017, Length=350, Percent_Identity=26, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17540018, Length=346, Percent_Identity=21.9653179190751, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221331183, Length=330, Percent_Identity=25.4545454545455, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI17647653, Length=330, Percent_Identity=25.4545454545455, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24664379, Length=330, Percent_Identity=25.4545454545455, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21357367, Length=357, Percent_Identity=22.4089635854342, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI45550968, Length=315, Percent_Identity=23.4920634920635, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI19921172, Length=315, Percent_Identity=23.4920634920635, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 41759; Mature: 41759

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSHADSPAAHHGGSLTIFQGAALYIGAVLGTGVIALPALAADVAGPASLLAWAALVVLS
CCCCCCCCCHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
APLAATFAALGARYPDAGGVSTYARRAFGPKAAAIVGWCFYFAVPAGAPAAAMFGGAYVA
HHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHCCEEEE
AVTGGGQTTVIATAAALIAIVSAANAFGVTVSGRMQLVLSALLVTLLLAAVLASAPHART
EEECCCCHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ANLHPFAPHGWLAVGQAAALLVWSFAGWEAITHLAAEFRRPAHDMPRSAGIAVVVVGLLY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHH
LSVAAASVMVLGPSAGASGAPLAELIAGGIGGHAQVLATAAALLLTLGTMNAYFAGAAKL
HHHHHHHEEEECCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAALGRDGALPAWLAQGSQVGGVPRRSLGAIAVLAAAALAATTLAGVGPTPLVLVTSGCF
HHHHCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHH
VMVYGLGAAAALKLLPRGSVAYRCAWISLIAVAGLFVTTGWYVVCPLLLAGGALLYLRMT
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
VRPG
ECCC
>Mature Secondary Structure
MRSHADSPAAHHGGSLTIFQGAALYIGAVLGTGVIALPALAADVAGPASLLAWAALVVLS
CCCCCCCCCHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
APLAATFAALGARYPDAGGVSTYARRAFGPKAAAIVGWCFYFAVPAGAPAAAMFGGAYVA
HHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHCCEEEE
AVTGGGQTTVIATAAALIAIVSAANAFGVTVSGRMQLVLSALLVTLLLAAVLASAPHART
EEECCCCHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ANLHPFAPHGWLAVGQAAALLVWSFAGWEAITHLAAEFRRPAHDMPRSAGIAVVVVGLLY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHH
LSVAAASVMVLGPSAGASGAPLAELIAGGIGGHAQVLATAAALLLTLGTMNAYFAGAAKL
HHHHHHHEEEECCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAALGRDGALPAWLAQGSQVGGVPRRSLGAIAVLAAAALAATTLAGVGPTPLVLVTSGCF
HHHHCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHH
VMVYGLGAAAALKLLPRGSVAYRCAWISLIAVAGLFVTTGWYVVCPLLLAGGALLYLRMT
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
VRPG
ECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969499; 9384377 [H]