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The map label for this gene is gbpR [H]

Identifier: 189352832

GI number: 189352832

Start: 955097

End: 956041

Strand: Reverse

Name: gbpR [H]

Synonym: BMULJ_04066

Alternate gene names: 189352832

Gene position: 956041-955097 (Counterclockwise)

Preceding gene: 189352838

Following gene: 189352827

Centisome position: 38.66

GC content: 69.74

Gene sequence:

>945_bases
ATGGACTGGACTTATCGTCTGCGGCTGCGGCATCTGCAGGTGCTGCTGAGCCTGGCGAGCACCGGCAATCTGAGCCAGTC
GGCGGCGGCGCTGGCGACCACGCAGCCGGCGTTGTCGAAGTGGCTGAAGGAACTCGAAGAGGATGTCGGGCTGCCGCTCT
TCGAGCGGCATGCGCGCGGGTTGCGGCCGACGCCGTACGGCGACGCGCTGATCGAGCACGCGCGCCGCGTGGAGGCGCAG
CTCGACGTCGCGCGCGACGACATGGCCGCACTGCGCGAAGGCGGCAGCGGCCTCGTGACGATCGGCACATCGGGCGTCGC
CGCCGCCGACACGGTGCCGCTCGCGGTGTCGCAATTGCTGAAACGGATGCCGCGCGCGCAGGTGCGGCTCAACGAAAGCA
CGCTGGTGCAGCTGATGCCGCAGCTCGCGCGCGGCGAGCTCGACATCGTCGTCGGCCGCACCGGCTCCGCGTCGGTCGAT
CCGCTGCTGCAGGTCGAAACGCTGTACGTCGATCCGGTCGTATTCGTCGCGCGGCCCGATCACCCGCTCGCCGGCGCGGC
TTCGGTCGGCTGGGACGACGTGCTGTCGTACACGTGGATCGTCTGGCCGGCCGGCACGCCGGTGCACAATGCGCTGCAGG
CGGCGCTATCGGCGGCCGGCCGCACGCAGCCGCCGCATTGCGTCGAATCGAACTCGTCGCTGCTCAATCTGACGCTGCTG
AACAATACGGACCTGCTCGGCGTCGCGTCGCAACGTGCCGCGCGACGCTTCGAGCAACTGAATGCGATCCGGATCCTGCC
GATGCGGCTCGAAGGCCAGGGCGCGGTCGCGATGTACTGGCACCCGGACAGCGCGAACCGCGCGGCCGTCGCGGCCGCGA
TCGAATGTCTGCGCGCATGCGCCGCACCGCAGATCGGCAGATGGGAGAAGGAAACGGCGGATTAG

Upstream 100 bases:

>100_bases
GCCCGTTGACCGATTTATATGCGACCAGACATATCCCGTAAAATGACCAAATCATCTAATCCATATGGTTCTGGATATAT
CTCTCGATACGAGGCAGGCA

Downstream 100 bases:

>100_bases
CGGCGGCGGCGCAGGCAGCCGGCATGCGCCGCGCTGCGTGCGCCGCCGTGCGTCACGCGCATTCGTCGGCGGCGGCGCCG
TCGAGCATCAGTGTGCCGAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MDWTYRLRLRHLQVLLSLASTGNLSQSAAALATTQPALSKWLKELEEDVGLPLFERHARGLRPTPYGDALIEHARRVEAQ
LDVARDDMAALREGGSGLVTIGTSGVAAADTVPLAVSQLLKRMPRAQVRLNESTLVQLMPQLARGELDIVVGRTGSASVD
PLLQVETLYVDPVVFVARPDHPLAGAASVGWDDVLSYTWIVWPAGTPVHNALQAALSAAGRTQPPHCVESNSSLLNLTLL
NNTDLLGVASQRAARRFEQLNAIRILPMRLEGQGAVAMYWHPDSANRAAVAAAIECLRACAAPQIGRWEKETAD

Sequences:

>Translated_314_residues
MDWTYRLRLRHLQVLLSLASTGNLSQSAAALATTQPALSKWLKELEEDVGLPLFERHARGLRPTPYGDALIEHARRVEAQ
LDVARDDMAALREGGSGLVTIGTSGVAAADTVPLAVSQLLKRMPRAQVRLNESTLVQLMPQLARGELDIVVGRTGSASVD
PLLQVETLYVDPVVFVARPDHPLAGAASVGWDDVLSYTWIVWPAGTPVHNALQAALSAAGRTQPPHCVESNSSLLNLTLL
NNTDLLGVASQRAARRFEQLNAIRILPMRLEGQGAVAMYWHPDSANRAAVAAAIECLRACAAPQIGRWEKETAD
>Mature_314_residues
MDWTYRLRLRHLQVLLSLASTGNLSQSAAALATTQPALSKWLKELEEDVGLPLFERHARGLRPTPYGDALIEHARRVEAQ
LDVARDDMAALREGGSGLVTIGTSGVAAADTVPLAVSQLLKRMPRAQVRLNESTLVQLMPQLARGELDIVVGRTGSASVD
PLLQVETLYVDPVVFVARPDHPLAGAASVGWDDVLSYTWIVWPAGTPVHNALQAALSAAGRTQPPHCVESNSSLLNLTLL
NNTDLLGVASQRAARRFEQLNAIRILPMRLEGQGAVAMYWHPDSANRAAVAAAIECLRACAAPQIGRWEKETAD

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081904, Length=242, Percent_Identity=29.7520661157025, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1787601, Length=203, Percent_Identity=27.0935960591133, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI145693105, Length=196, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787530, Length=218, Percent_Identity=23.8532110091743, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI157672245, Length=262, Percent_Identity=25.9541984732824, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790262, Length=202, Percent_Identity=28.7128712871287, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790399, Length=220, Percent_Identity=25.4545454545455, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789506, Length=241, Percent_Identity=21.9917012448133, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788887, Length=183, Percent_Identity=28.9617486338798, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI2367136, Length=205, Percent_Identity=27.3170731707317, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789204, Length=196, Percent_Identity=29.0816326530612, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788297, Length=146, Percent_Identity=29.4520547945205, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787806, Length=195, Percent_Identity=23.0769230769231, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33903; Mature: 33903

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWTYRLRLRHLQVLLSLASTGNLSQSAAALATTQPALSKWLKELEEDVGLPLFERHARG
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHCCC
LRPTPYGDALIEHARRVEAQLDVARDDMAALREGGSGLVTIGTSGVAAADTVPLAVSQLL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHH
KRMPRAQVRLNESTLVQLMPQLARGELDIVVGRTGSASVDPLLQVETLYVDPVVFVARPD
HHCCHHEEEECHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEEEECCEEEEECCC
HPLAGAASVGWDDVLSYTWIVWPAGTPVHNALQAALSAAGRTQPPHCVESNSSLLNLTLL
CCCCCCCCCCHHHHHHEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEE
NNTDLLGVASQRAARRFEQLNAIRILPMRLEGQGAVAMYWHPDSANRAAVAAAIECLRAC
CCCCEEEHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHH
AAPQIGRWEKETAD
CCCCCCCCCCCCCC
>Mature Secondary Structure
MDWTYRLRLRHLQVLLSLASTGNLSQSAAALATTQPALSKWLKELEEDVGLPLFERHARG
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHCCC
LRPTPYGDALIEHARRVEAQLDVARDDMAALREGGSGLVTIGTSGVAAADTVPLAVSQLL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHH
KRMPRAQVRLNESTLVQLMPQLARGELDIVVGRTGSASVDPLLQVETLYVDPVVFVARPD
HHCCHHEEEECHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEEEECCEEEEECCC
HPLAGAASVGWDDVLSYTWIVWPAGTPVHNALQAALSAAGRTQPPHCVESNSSLLNLTLL
CCCCCCCCCCHHHHHHEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEE
NNTDLLGVASQRAARRFEQLNAIRILPMRLEGQGAVAMYWHPDSANRAAVAAAIECLRAC
CCCCEEEHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHH
AAPQIGRWEKETAD
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]