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The map label for this gene is cueR [H]

Identifier: 189352816

GI number: 189352816

Start: 936822

End: 937247

Strand: Direct

Name: cueR [H]

Synonym: BMULJ_04048

Alternate gene names: 189352816

Gene position: 936822-937247 (Clockwise)

Preceding gene: 189352814

Following gene: 189352819

Centisome position: 37.88

GC content: 69.95

Gene sequence:

>426_bases
ATGGGACGACTGGATATCGCCGAGGTCGCGCGGCGCACGGGGCTGCCCGCGTCGACGCTGCGTTTTTACGAGGAAAAGGG
GCTGATCGAGCCGACCGGGCGCACCGGGCTGCGGCGTCAATACGACGAGTCGGTGCTCGAGCGGCTCGCGCTGATCGCGC
TCGGCCGCGAGGCCGGTTTTTCGCTCGACGAGATCGTCGCGATGTTCGGCGCCGACGGCCGTCCCGCGATCGACCGCGCG
AAGCTCGAGGAGAAGGCCGACGCGATCGATCGGACGATCCGTCGTCTCGCGGCCGTGCGCGACGCATTGCGCTACGCGGC
GTCGTGTCCGGCACCGAGCCATCTCGAATGTCCGTCGTTCCGGCAGCTGATGCGCGTCGCCGCGCACCGGCATCCTGCGC
ATCGCGCGAAGGCCGAGCGCGCTTAG

Upstream 100 bases:

>100_bases
GCGCGGCAGGCAGCGGGCAGGTGGGTTTCATCGGTGGTCGGACTTGTCGTCGTGGATCGCGGCGGCTATCTTGCAACTTC
AAGCTCACTTGAGGTCAAGC

Downstream 100 bases:

>100_bases
TGCGGGTGGGGGCACGGGGCGTGTGGGCGCGTGCGGGTCAGCGCGCGTAATACGCGCGGCATTCCATCTCGCGCCCGCGC
ACGATGCGTTTGCCGACAAG

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: Copper efflux regulator; Copper export regulator [H]

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MGRLDIAEVARRTGLPASTLRFYEEKGLIEPTGRTGLRRQYDESVLERLALIALGREAGFSLDEIVAMFGADGRPAIDRA
KLEEKADAIDRTIRRLAAVRDALRYAASCPAPSHLECPSFRQLMRVAAHRHPAHRAKAERA

Sequences:

>Translated_141_residues
MGRLDIAEVARRTGLPASTLRFYEEKGLIEPTGRTGLRRQYDESVLERLALIALGREAGFSLDEIVAMFGADGRPAIDRA
KLEEKADAIDRTIRRLAAVRDALRYAASCPAPSHLECPSFRQLMRVAAHRHPAHRAKAERA
>Mature_140_residues
GRLDIAEVARRTGLPASTLRFYEEKGLIEPTGRTGLRRQYDESVLERLALIALGREAGFSLDEIVAMFGADGRPAIDRAK
LEEKADAIDRTIRRLAAVRDALRYAASCPAPSHLECPSFRQLMRVAAHRHPAHRAKAERA

Specific function: Regulates the transcription of the copA and cueO genes. It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=133, Percent_Identity=35.3383458646617, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1790498, Length=117, Percent_Identity=35.042735042735, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 15676; Mature: 15545

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRLDIAEVARRTGLPASTLRFYEEKGLIEPTGRTGLRRQYDESVLERLALIALGREAGF
CCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
SLDEIVAMFGADGRPAIDRAKLEEKADAIDRTIRRLAAVRDALRYAASCPAPSHLECPSF
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
RQLMRVAAHRHPAHRAKAERA
HHHHHHHHHCCHHHHHHCCCC
>Mature Secondary Structure 
GRLDIAEVARRTGLPASTLRFYEEKGLIEPTGRTGLRRQYDESVLERLALIALGREAGF
CCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
SLDEIVAMFGADGRPAIDRAKLEEKADAIDRTIRRLAAVRDALRYAASCPAPSHLECPSF
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
RQLMRVAAHRHPAHRAKAERA
HHHHHHHHHCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA