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The map label for this gene is paaG [C]

Identifier: 189352773

GI number: 189352773

Start: 887396

End: 888190

Strand: Direct

Name: paaG [C]

Synonym: BMULJ_04005

Alternate gene names: 189352773

Gene position: 887396-888190 (Clockwise)

Preceding gene: 189352772

Following gene: 189352775

Centisome position: 35.88

GC content: 70.19

Gene sequence:

>795_bases
ATGGAACCCGATCACGCGACTTCCGAGCCGATCCTGTTGCGCGACATGCGCGACGGCGTCGTCACGCTGCGGCTGAACCG
GCCGCGGCAGTTCAACGCCTTGTCCGAAGCGATGCTGGCCAGCCTGCAGGACGCATTCGATTCGCTGGCCGCCGACGCGC
GCGTGCGCTGCGTCGTGCTGGCCGCCGAAGGCAAGGCGTTCTGCGCGGGGCACGACCTGCGCGAGATGCGCAGCAAGCCC
GATCTCGACTATTACCGCACGCTGTTCGCGCAATGCAGCCGCGTGATGCTCGCGATGCGCGCACTGCCGGTGCCGGTGAT
CGCGCGCGTGCACGGGATCGCGACGGCGGCCGGCTGCCAGCTCGTCGCCGCCTGCGATCTCGCGATCGCCGCCGACACCG
CGCGCTTCGCGGTGTCCGGCATCAACGTCGGGCTGTTCTGTTCGACGCCGGCCGTCGCACTGAGCCGCAACGTATCGGCC
AAGCGCGCGTTCGACATGCTCGTGACCGGGCGCTTCGTCGATGCGGCGACGGCCGCCGCGTGGGGCCTCGTCAACGAGGC
CGTGCCGGCCGATGCGCTCGACGCGGCGGTCGCGCGCAAGGTCGCGGAGATCGTCGCGAAGAGCCCGGCCGCGGTGCGCT
ACGGCAAGCAGATGTTCTACCGGCAGCGCGAACTGCCGCTCGACGACGCGTATGCGTACGCGGGCGACGTGATGGCGCGC
AACATGATGGAAGAGGATGCCGGCGAGGGCATCGATGCGTTCCTGGAAAAGCGCGCGCCGACGTGGCGCGCGTAG

Upstream 100 bases:

>100_bases
GCCGGCGACTGGACGGCGCGCCGAATGTGGAGGACCATTTGACCGTCTTCGTCTGTCGATGCCGGAGCGAATCCGGCCGA
ACCTCGTCGAGCGGAACATC

Downstream 100 bases:

>100_bases
CGGGGCGCGGGCGCTGCGCTACGATCGGCGCGGCGCTGACCGGAACGCGGCGACGCGCGCGCCGCGCGTTCAGCGCCCGT
AGCTGCCGGTGCGCAGCGCG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MEPDHATSEPILLRDMRDGVVTLRLNRPRQFNALSEAMLASLQDAFDSLAADARVRCVVLAAEGKAFCAGHDLREMRSKP
DLDYYRTLFAQCSRVMLAMRALPVPVIARVHGIATAAGCQLVAACDLAIAADTARFAVSGINVGLFCSTPAVALSRNVSA
KRAFDMLVTGRFVDAATAAAWGLVNEAVPADALDAAVARKVAEIVAKSPAAVRYGKQMFYRQRELPLDDAYAYAGDVMAR
NMMEEDAGEGIDAFLEKRAPTWRA

Sequences:

>Translated_264_residues
MEPDHATSEPILLRDMRDGVVTLRLNRPRQFNALSEAMLASLQDAFDSLAADARVRCVVLAAEGKAFCAGHDLREMRSKP
DLDYYRTLFAQCSRVMLAMRALPVPVIARVHGIATAAGCQLVAACDLAIAADTARFAVSGINVGLFCSTPAVALSRNVSA
KRAFDMLVTGRFVDAATAAAWGLVNEAVPADALDAAVARKVAEIVAKSPAAVRYGKQMFYRQRELPLDDAYAYAGDVMAR
NMMEEDAGEGIDAFLEKRAPTWRA
>Mature_264_residues
MEPDHATSEPILLRDMRDGVVTLRLNRPRQFNALSEAMLASLQDAFDSLAADARVRCVVLAAEGKAFCAGHDLREMRSKP
DLDYYRTLFAQCSRVMLAMRALPVPVIARVHGIATAAGCQLVAACDLAIAADTARFAVSGINVGLFCSTPAVALSRNVSA
KRAFDMLVTGRFVDAATAAAWGLVNEAVPADALDAAVARKVAEIVAKSPAAVRYGKQMFYRQRELPLDDAYAYAGDVMAR
NMMEEDAGEGIDAFLEKRAPTWRA

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI31542718, Length=245, Percent_Identity=44.4897959183673, Blast_Score=213, Evalue=1e-55,
Organism=Homo sapiens, GI194097323, Length=251, Percent_Identity=28.6852589641434, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI70995211, Length=273, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI4502327, Length=258, Percent_Identity=28.2945736434109, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI260274832, Length=262, Percent_Identity=23.2824427480916, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI45643119, Length=262, Percent_Identity=23.2824427480916, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI260275230, Length=262, Percent_Identity=23.2824427480916, Blast_Score=71, Evalue=8e-13,
Organism=Escherichia coli, GI1787659, Length=259, Percent_Identity=33.2046332046332, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI221142681, Length=263, Percent_Identity=30.4182509505703, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI87082183, Length=257, Percent_Identity=28.0155642023346, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788597, Length=263, Percent_Identity=31.1787072243346, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787660, Length=264, Percent_Identity=29.5454545454545, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790281, Length=182, Percent_Identity=29.6703296703297, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788682, Length=202, Percent_Identity=25.7425742574257, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17540306, Length=250, Percent_Identity=39.6, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17554946, Length=249, Percent_Identity=28.9156626506024, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17536985, Length=278, Percent_Identity=26.6187050359712, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17560910, Length=202, Percent_Identity=33.1683168316832, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI25145438, Length=252, Percent_Identity=26.984126984127, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17540714, Length=204, Percent_Identity=28.921568627451, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17534483, Length=283, Percent_Identity=22.9681978798587, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17535521, Length=255, Percent_Identity=27.0588235294118, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17549921, Length=216, Percent_Identity=28.7037037037037, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI19922422, Length=259, Percent_Identity=37.8378378378378, Blast_Score=194, Evalue=7e-50,
Organism=Drosophila melanogaster, GI20129971, Length=246, Percent_Identity=29.6747967479675, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24653477, Length=246, Percent_Identity=29.6747967479675, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24653139, Length=257, Percent_Identity=29.5719844357977, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI19920382, Length=252, Percent_Identity=29.3650793650794, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI21357171, Length=257, Percent_Identity=29.1828793774319, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24650670, Length=220, Percent_Identity=29.5454545454545, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583165, Length=211, Percent_Identity=27.4881516587678, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 28498; Mature: 28498

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPDHATSEPILLRDMRDGVVTLRLNRPRQFNALSEAMLASLQDAFDSLAADARVRCVVL
CCCCCCCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
AAEGKAFCAGHDLREMRSKPDLDYYRTLFAQCSRVMLAMRALPVPVIARVHGIATAAGCQ
EECCCEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LVAACDLAIAADTARFAVSGINVGLFCSTPAVALSRNVSAKRAFDMLVTGRFVDAATAAA
HHHHHHHHHHHCHHHHHHCCCCEEEEECCCHHHHHCCCHHHHHHHHHHHCHHHHHHHHHH
WGLVNEAVPADALDAAVARKVAEIVAKSPAAVRYGKQMFYRQRELPLDDAYAYAGDVMAR
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
NMMEEDAGEGIDAFLEKRAPTWRA
HHHHHHCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MEPDHATSEPILLRDMRDGVVTLRLNRPRQFNALSEAMLASLQDAFDSLAADARVRCVVL
CCCCCCCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
AAEGKAFCAGHDLREMRSKPDLDYYRTLFAQCSRVMLAMRALPVPVIARVHGIATAAGCQ
EECCCEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LVAACDLAIAADTARFAVSGINVGLFCSTPAVALSRNVSAKRAFDMLVTGRFVDAATAAA
HHHHHHHHHHHCHHHHHHCCCCEEEEECCCHHHHHCCCHHHHHHHHHHHCHHHHHHHHHH
WGLVNEAVPADALDAAVARKVAEIVAKSPAAVRYGKQMFYRQRELPLDDAYAYAGDVMAR
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
NMMEEDAGEGIDAFLEKRAPTWRA
HHHHHHCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA