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The map label for this gene is frzE [H]

Identifier: 189352768

GI number: 189352768

Start: 882124

End: 884535

Strand: Direct

Name: frzE [H]

Synonym: BMULJ_04000

Alternate gene names: 189352768

Gene position: 882124-884535 (Clockwise)

Preceding gene: 189352766

Following gene: 189352769

Centisome position: 35.67

GC content: 67.66

Gene sequence:

>2412_bases
ATGACCATTCGTCATCGCATTACGTTGCTGGTTGTTCTGACGTTCGTCGCGTTGTCCGCGATCGGCGTCTATGCCGTGTA
CCAGACGCGCAAGAGCGCATCCGAGGTTCGCCAGGTCACGCAGGGCATCGTGCCGAGCGCGCTCGCGTCGGCCGATCTCG
TCGCCGACGTGAAGAACATCCAGATCGCGACGATGACGCTCGTGTACGCGCCCGACTCCAACACCGTCGCGCAGGCGGCC
GACGAGCTGAAGACGAAGGAGGCCGCATTGCGCGCGGCGCTCGACGCGCAGGCGCGCTCGGCGGTCGGCCGCGCGCAGCA
GGGCCTCGTCGCGCAGGCGAAGGACAGCGCCGCGAACTACTTCGCGGCGATCGACGACACCGTGAAGATGAAGACGGCCG
GCAAGGCCGAAGTGGCGCAGGCGTACCTGTTCGCGAACGTCGCGCAGTACCGCGACGAACTCGAAAGCATCGTCGATACG
CTGCGCGTCGAGAAGAACCGGCAGAAGGACGACGCGATCCTTGCACTGAACGGCATGCTGTCGACGACGGCGACCGCGAT
CGGCGGCGTCGCCGGCACGGTCGTCGTGCTGCTGACCGCGCTCGGCTTCGTGCTGTATCGGCAGATCACGCGTCCGCTGA
GCCGGATGCAGACGATGATGAGCGAGATCGCGACGAGCCAGGACTTCACGCGCCGCGTGCCGGTGGGGCGGATGGACGAG
ATCGGCCACTCGATCGTCGCGTTCAACGGGATGATCGAGAAGATCCAGGAGAACGCCGCGCAACTGAAGCAGAAGACGGC
CGACATCCAGGCGATGCTGCAGAACATGCAGCAGGGGATTCTGACGGTGGTCGATGGCGGCGTCGTGCATGCCGAATATT
CGGCGTACCTCGAGACGATCTTCGAGACGCGCGACATCGCCGGGCGCGACCTGATGGCGCTCGTGTTCGACGATTCGGAC
CTCGGCTCGGACGCACGTTCGCAGGTCGAGGCGGCCGTGCACGCCTGCCTCGGCGAGGACAGCATGAACTTCGCGTTCAA
CGAGCATCTGCTCGTGAACGAAGTCGCGAAACGGATGCCGGACGGCCGTCACAAGTGGCTCGACCTGAGCTGGTCGGCGA
TCACCGACGAGACCGATACGGTCGTGCGGCTGATGCTGTGCGTGCGCGACGTGACCGAGATCCGCGAGCTGACTGCGCAG
GCCGGCGAGCAGCAGCGCCGCCTCGAGATGATCGGCGAGATTCTCGCGATCAGCCAGGACAAGTTCCACGACTTCGTGCA
CAGCGCGAAGGGCTTCCTCAGCGAGAACGAGCGGATGATCCGTCAGCACGAGCGCGCGGATCACTCGGTCGTCGCCGCAC
TGTTCCGCAACATGCATACGATCAAGGGCAACGCGCGTACGTACAGCCTGCAGCATCTGACCAACATCGTGCACGAAGCC
GAGCAGGCGTACGAATCGCTGCGCCGCGCGGACAGCGGCCCCGAATGGAACCGCGACGCGCTGATGGAAGATCTTGCGCG
CGTACGCGAAGCCATCGACCACTACGCGACGATCAACGCCGTCACGCTCGGCCGCAGTGGCGGCCCGACCGACGGCGCAC
CGGCCGATTATCTGATGGTCGAGCGTGCGCATATCAGCGAAAGCCTGCGGATGCTCGATCGCGCCGACCCGGCAAACGCG
GCCGACTGGCGCGCGGCGCGCGATGCCGTGCGCCGGATGCTGAGCCAGCTCGGCACGCAGGGGATCGGCGACGCGCTCGG
CGGCGTGATCGAATCGCTGCCGTCGCTCGCGACCGAACTCGGCAAGCCGGCGCCCGTCGTGCACATCGACAGCGGCGGCT
GGCGCGTGCGCAGCGAGATCGCGCCGACGCTGAAGAACGTCTTCATGCACCTGATGCGCAATGCGATCGATCACGGGATC
GAGACGTCGGACGAACGCCGTGCGGCGGGCAAGCCGGCGGCGGGCACGATCGACGTCGCGGTCGACGTCGATGCAGATGC
GCTGCGCTTTGTGCTGCGCGACGACGGCCGCGGGCTCGCGCTCGAGCGCATTCGAGCGATCGCGCAGGAACGCGGCTGGC
TCGATGCGGATGCGCCCGCGCTGTCGGACGAGGCGGTCGCCGAACTGATCTTCCGGCCGGGCTTCTCCACCGCGCGTGCG
GTGACCGAGGTATCGGGGCGCGGGGTCGGGATGGACGCGGTACGCAACTTCCTGAAGCGCGACGGCGGCGACATCGTGCT
GCGCTTTACCGACGCGTGCGTCGGCGCGCCGTATCGTGCGTTCGAGACGATCGTGTCGCTGCCCGCGCGCTTCGCGGCGG
ACGGCCACGCGCACGGCGACGGGCACGCGGCCGGCGCCGCCCGGCAGCCGGCCGACGCGGGCATCGGCGCACGCTTCAGC
ACCGCGGAGTGA

Upstream 100 bases:

>100_bases
TCATCAGACAGTCATATACCTTCCCCGATAATTCGGCGCTCACATTCTTTCAACAGACCAGAGCGCGAGTGAAATCGAAT
CGCGGCGGGGAGCAGTTCAC

Downstream 100 bases:

>100_bases
CCGTGAGCGTCTGGACGATCGCGAGCGCCGCGGCACTCGCATCCGGTTTCGTCGTCGCGCTGGCCGCAATCGGCGTGTTC
CGCGTGCGCGACGCACGGCG

Product: putative signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 803; Mature: 802

Protein sequence:

>803_residues
MTIRHRITLLVVLTFVALSAIGVYAVYQTRKSASEVRQVTQGIVPSALASADLVADVKNIQIATMTLVYAPDSNTVAQAA
DELKTKEAALRAALDAQARSAVGRAQQGLVAQAKDSAANYFAAIDDTVKMKTAGKAEVAQAYLFANVAQYRDELESIVDT
LRVEKNRQKDDAILALNGMLSTTATAIGGVAGTVVVLLTALGFVLYRQITRPLSRMQTMMSEIATSQDFTRRVPVGRMDE
IGHSIVAFNGMIEKIQENAAQLKQKTADIQAMLQNMQQGILTVVDGGVVHAEYSAYLETIFETRDIAGRDLMALVFDDSD
LGSDARSQVEAAVHACLGEDSMNFAFNEHLLVNEVAKRMPDGRHKWLDLSWSAITDETDTVVRLMLCVRDVTEIRELTAQ
AGEQQRRLEMIGEILAISQDKFHDFVHSAKGFLSENERMIRQHERADHSVVAALFRNMHTIKGNARTYSLQHLTNIVHEA
EQAYESLRRADSGPEWNRDALMEDLARVREAIDHYATINAVTLGRSGGPTDGAPADYLMVERAHISESLRMLDRADPANA
ADWRAARDAVRRMLSQLGTQGIGDALGGVIESLPSLATELGKPAPVVHIDSGGWRVRSEIAPTLKNVFMHLMRNAIDHGI
ETSDERRAAGKPAAGTIDVAVDVDADALRFVLRDDGRGLALERIRAIAQERGWLDADAPALSDEAVAELIFRPGFSTARA
VTEVSGRGVGMDAVRNFLKRDGGDIVLRFTDACVGAPYRAFETIVSLPARFAADGHAHGDGHAAGAARQPADAGIGARFS
TAE

Sequences:

>Translated_803_residues
MTIRHRITLLVVLTFVALSAIGVYAVYQTRKSASEVRQVTQGIVPSALASADLVADVKNIQIATMTLVYAPDSNTVAQAA
DELKTKEAALRAALDAQARSAVGRAQQGLVAQAKDSAANYFAAIDDTVKMKTAGKAEVAQAYLFANVAQYRDELESIVDT
LRVEKNRQKDDAILALNGMLSTTATAIGGVAGTVVVLLTALGFVLYRQITRPLSRMQTMMSEIATSQDFTRRVPVGRMDE
IGHSIVAFNGMIEKIQENAAQLKQKTADIQAMLQNMQQGILTVVDGGVVHAEYSAYLETIFETRDIAGRDLMALVFDDSD
LGSDARSQVEAAVHACLGEDSMNFAFNEHLLVNEVAKRMPDGRHKWLDLSWSAITDETDTVVRLMLCVRDVTEIRELTAQ
AGEQQRRLEMIGEILAISQDKFHDFVHSAKGFLSENERMIRQHERADHSVVAALFRNMHTIKGNARTYSLQHLTNIVHEA
EQAYESLRRADSGPEWNRDALMEDLARVREAIDHYATINAVTLGRSGGPTDGAPADYLMVERAHISESLRMLDRADPANA
ADWRAARDAVRRMLSQLGTQGIGDALGGVIESLPSLATELGKPAPVVHIDSGGWRVRSEIAPTLKNVFMHLMRNAIDHGI
ETSDERRAAGKPAAGTIDVAVDVDADALRFVLRDDGRGLALERIRAIAQERGWLDADAPALSDEAVAELIFRPGFSTARA
VTEVSGRGVGMDAVRNFLKRDGGDIVLRFTDACVGAPYRAFETIVSLPARFAADGHAHGDGHAAGAARQPADAGIGARFS
TAE
>Mature_802_residues
TIRHRITLLVVLTFVALSAIGVYAVYQTRKSASEVRQVTQGIVPSALASADLVADVKNIQIATMTLVYAPDSNTVAQAAD
ELKTKEAALRAALDAQARSAVGRAQQGLVAQAKDSAANYFAAIDDTVKMKTAGKAEVAQAYLFANVAQYRDELESIVDTL
RVEKNRQKDDAILALNGMLSTTATAIGGVAGTVVVLLTALGFVLYRQITRPLSRMQTMMSEIATSQDFTRRVPVGRMDEI
GHSIVAFNGMIEKIQENAAQLKQKTADIQAMLQNMQQGILTVVDGGVVHAEYSAYLETIFETRDIAGRDLMALVFDDSDL
GSDARSQVEAAVHACLGEDSMNFAFNEHLLVNEVAKRMPDGRHKWLDLSWSAITDETDTVVRLMLCVRDVTEIRELTAQA
GEQQRRLEMIGEILAISQDKFHDFVHSAKGFLSENERMIRQHERADHSVVAALFRNMHTIKGNARTYSLQHLTNIVHEAE
QAYESLRRADSGPEWNRDALMEDLARVREAIDHYATINAVTLGRSGGPTDGAPADYLMVERAHISESLRMLDRADPANAA
DWRAARDAVRRMLSQLGTQGIGDALGGVIESLPSLATELGKPAPVVHIDSGGWRVRSEIAPTLKNVFMHLMRNAIDHGIE
TSDERRAAGKPAAGTIDVAVDVDADALRFVLRDDGRGLALERIRAIAQERGWLDADAPALSDEAVAELIFRPGFSTARAV
TEVSGRGVGMDAVRNFLKRDGGDIVLRFTDACVGAPYRAFETIVSLPARFAADGHAHGDGHAAGAARQPADAGIGARFST
AE

Specific function: FrzE is involved in a sensory transduction pathway that controls the frequency at which cells reverse their gliding direction. FrzE seems to be capable of autophosphorylating itself on an histidine residue and then to transfer that group to an aspartate r

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=150, Percent_Identity=40.6666666666667, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR005467
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01584 CheW; PF02518 HATPase_c; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 87198; Mature: 87067

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS50885 HAMP ; PS50894 HPT ; PS50113 PAC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRHRITLLVVLTFVALSAIGVYAVYQTRKSASEVRQVTQGIVPSALASADLVADVKNI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCE
QIATMTLVYAPDSNTVAQAADELKTKEAALRAALDAQARSAVGRAQQGLVAQAKDSAANY
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FAAIDDTVKMKTAGKAEVAQAYLFANVAQYRDELESIVDTLRVEKNRQKDDAILALNGML
HHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHH
STTATAIGGVAGTVVVLLTALGFVLYRQITRPLSRMQTMMSEIATSQDFTRRVPVGRMDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHH
IGHSIVAFNGMIEKIQENAAQLKQKTADIQAMLQNMQQGILTVVDGGVVHAEYSAYLETI
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCEEEHHHHHHHHHH
FETRDIAGRDLMALVFDDSDLGSDARSQVEAAVHACLGEDSMNFAFNEHLLVNEVAKRMP
HHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHCC
DGRHKWLDLSWSAITDETDTVVRLMLCVRDVTEIRELTAQAGEQQRRLEMIGEILAISQD
CCCCCEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KFHDFVHSAKGFLSENERMIRQHERADHSVVAALFRNMHTIKGNARTYSLQHLTNIVHEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHH
EQAYESLRRADSGPEWNRDALMEDLARVREAIDHYATINAVTLGRSGGPTDGAPADYLMV
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHH
ERAHISESLRMLDRADPANAADWRAARDAVRRMLSQLGTQGIGDALGGVIESLPSLATEL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GKPAPVVHIDSGGWRVRSEIAPTLKNVFMHLMRNAIDHGIETSDERRAAGKPAAGTIDVA
CCCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCEEEEE
VDVDADALRFVLRDDGRGLALERIRAIAQERGWLDADAPALSDEAVAELIFRPGFSTARA
EECCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHH
VTEVSGRGVGMDAVRNFLKRDGGDIVLRFTDACVGAPYRAFETIVSLPARFAADGHAHGD
HHHHCCCCCCHHHHHHHHHCCCCCEEEEEEHHHHCCCHHHHHHHHHHHHHHCCCCCCCCC
GHAAGAARQPADAGIGARFSTAE
CCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TIRHRITLLVVLTFVALSAIGVYAVYQTRKSASEVRQVTQGIVPSALASADLVADVKNI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCE
QIATMTLVYAPDSNTVAQAADELKTKEAALRAALDAQARSAVGRAQQGLVAQAKDSAANY
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FAAIDDTVKMKTAGKAEVAQAYLFANVAQYRDELESIVDTLRVEKNRQKDDAILALNGML
HHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHH
STTATAIGGVAGTVVVLLTALGFVLYRQITRPLSRMQTMMSEIATSQDFTRRVPVGRMDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHH
IGHSIVAFNGMIEKIQENAAQLKQKTADIQAMLQNMQQGILTVVDGGVVHAEYSAYLETI
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCEEEHHHHHHHHHH
FETRDIAGRDLMALVFDDSDLGSDARSQVEAAVHACLGEDSMNFAFNEHLLVNEVAKRMP
HHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHCC
DGRHKWLDLSWSAITDETDTVVRLMLCVRDVTEIRELTAQAGEQQRRLEMIGEILAISQD
CCCCCEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KFHDFVHSAKGFLSENERMIRQHERADHSVVAALFRNMHTIKGNARTYSLQHLTNIVHEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHH
EQAYESLRRADSGPEWNRDALMEDLARVREAIDHYATINAVTLGRSGGPTDGAPADYLMV
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHH
ERAHISESLRMLDRADPANAADWRAARDAVRRMLSQLGTQGIGDALGGVIESLPSLATEL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GKPAPVVHIDSGGWRVRSEIAPTLKNVFMHLMRNAIDHGIETSDERRAAGKPAAGTIDVA
CCCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCEEEEE
VDVDADALRFVLRDDGRGLALERIRAIAQERGWLDADAPALSDEAVAELIFRPGFSTARA
EECCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHH
VTEVSGRGVGMDAVRNFLKRDGGDIVLRFTDACVGAPYRAFETIVSLPARFAADGHAHGD
HHHHCCCCCCHHHHHHHHHCCCCCEEEEEEHHHHCCCHHHHHHHHHHHHHHCCCCCCCCC
GHAAGAARQPADAGIGARFSTAE
CCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2165608; 2123853 [H]