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The map label for this gene is cph2 [H]

Identifier: 189352743

GI number: 189352743

Start: 850717

End: 851754

Strand: Reverse

Name: cph2 [H]

Synonym: BMULJ_03975

Alternate gene names: 189352743

Gene position: 851754-850717 (Counterclockwise)

Preceding gene: 189352744

Following gene: 189352740

Centisome position: 34.44

GC content: 70.13

Gene sequence:

>1038_bases
ATGACTAGCGACCCGACGCGCCTGCCGCCCGTTCACGCGCCGCACGCGCCGCCCACCGATGCACCGGCAATGGTGCTGCC
GGTCGACGATCAGACGATCGTCGCGGAAGCCGTGCGACGCGCGCTCGTCGACGAGGCCGGCATCGACTTCCACTACTGCG
CGCGCTCCGACGACGCGATGGCCGCGGCGATCGACACGCGCCCGACCGTGATCCTGCAGGACCTCGTGATGCCCGGCACT
GACGGCCTGACGCTCGTGCACGCGTATCGTGCACATCCGGCGACGCGCGACGTGCCGATCATCGTGCTGTCGACGCAGGA
AGAGCCGACGATCAAGCGCACCGCGTTCGCGGCCGGCGCGAACGACTATCTCGTGAAGCTGCCGGACCGCATCGAGCTCA
TCGCGCGCATCCGCTACCACTCGCGCTCGTACATGAACCTGCTGCAGCGCGACGATGCCTACCGCGCTCTGCGGCAATCG
CAGCAGCAACTGCTCGAAGCCAATCTCGAACTGCGGCGCCTCATGCATTCGGACGGTCTGACCGGGCTGTCGAATCGCCG
CTATCTCGACGAATACCTGGCCGCCGAGTGGCGGCGCGGCACGCGCGAGCGCGCGGAACTGTCGCTGCTGATGATCGACG
TCGACCACTTCAAGCTCTACAACGACACCTACGGCCACGTGGCGGGCGATCAGGTGCTGCGGCAGGTCGCGGCGACCATC
GCGCAGTGCCTGCGGCCGTCCGGCGATCTCGCCGCGCGTTTCGGCGGCGAGGAGTTCGCGGTCGTGATGCCCGGCACGTC
GGCGGGCGCCGCGCGACTGCTCGGCGAGAAGATCCGGCTCGCGGTCGACGCGCTGCGGCTCGAGCACGGGCAGTCGACGG
CCGGCCACGTGACGGTTAGCATCGGCGGCGCGAGCATCGTGCCGGCGCCCGGTCTGCCGACGACGGCGCTGATCGAGGCC
GCCGATCGCGCGCTCTATCGTGCGAAGCACGACGGCCGCAACCGCGTCGAGGTCGACCCGCCGCCGCCCGCGCGTTGA

Upstream 100 bases:

>100_bases
CGCTCGAGCGCATCGCGAGCGAACTCGCGACGCTCGTGCGCATCTGAACCTGCCGCGCCTCACCGACGACTTCCCGCCAT
GACAGACCCACGCATCGACC

Downstream 100 bases:

>100_bases
GTGTGCGTCGCGCGACCGTCACGCCAGCGCGAAACGCCGTGCGTAGTCGACGGGATCGAGCGGCCGGCTGAACAGATAGC
CCTGTTGCATGTCGCAGCCG

Product: PleD-related family two-component system response regulator

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MTSDPTRLPPVHAPHAPPTDAPAMVLPVDDQTIVAEAVRRALVDEAGIDFHYCARSDDAMAAAIDTRPTVILQDLVMPGT
DGLTLVHAYRAHPATRDVPIIVLSTQEEPTIKRTAFAAGANDYLVKLPDRIELIARIRYHSRSYMNLLQRDDAYRALRQS
QQQLLEANLELRRLMHSDGLTGLSNRRYLDEYLAAEWRRGTRERAELSLLMIDVDHFKLYNDTYGHVAGDQVLRQVAATI
AQCLRPSGDLAARFGGEEFAVVMPGTSAGAARLLGEKIRLAVDALRLEHGQSTAGHVTVSIGGASIVPAPGLPTTALIEA
ADRALYRAKHDGRNRVEVDPPPPAR

Sequences:

>Translated_345_residues
MTSDPTRLPPVHAPHAPPTDAPAMVLPVDDQTIVAEAVRRALVDEAGIDFHYCARSDDAMAAAIDTRPTVILQDLVMPGT
DGLTLVHAYRAHPATRDVPIIVLSTQEEPTIKRTAFAAGANDYLVKLPDRIELIARIRYHSRSYMNLLQRDDAYRALRQS
QQQLLEANLELRRLMHSDGLTGLSNRRYLDEYLAAEWRRGTRERAELSLLMIDVDHFKLYNDTYGHVAGDQVLRQVAATI
AQCLRPSGDLAARFGGEEFAVVMPGTSAGAARLLGEKIRLAVDALRLEHGQSTAGHVTVSIGGASIVPAPGLPTTALIEA
ADRALYRAKHDGRNRVEVDPPPPAR
>Mature_344_residues
TSDPTRLPPVHAPHAPPTDAPAMVLPVDDQTIVAEAVRRALVDEAGIDFHYCARSDDAMAAAIDTRPTVILQDLVMPGTD
GLTLVHAYRAHPATRDVPIIVLSTQEEPTIKRTAFAAGANDYLVKLPDRIELIARIRYHSRSYMNLLQRDDAYRALRQSQ
QQLLEANLELRRLMHSDGLTGLSNRRYLDEYLAAEWRRGTRERAELSLLMIDVDHFKLYNDTYGHVAGDQVLRQVAATIA
QCLRPSGDLAARFGGEEFAVVMPGTSAGAARLLGEKIRLAVDALRLEHGQSTAGHVTVSIGGASIVPAPGLPTTALIEAA
DRALYRAKHDGRNRVEVDPPPPAR

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=184, Percent_Identity=35.8695652173913, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87081881, Length=177, Percent_Identity=40.6779661016949, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI145693134, Length=161, Percent_Identity=39.7515527950311, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787262, Length=168, Percent_Identity=36.9047619047619, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787816, Length=159, Percent_Identity=37.7358490566038, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87082007, Length=177, Percent_Identity=36.7231638418079, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1787802, Length=162, Percent_Identity=39.5061728395062, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787541, Length=171, Percent_Identity=34.5029239766082, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1788381, Length=187, Percent_Identity=32.620320855615, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081977, Length=172, Percent_Identity=33.1395348837209, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788085, Length=164, Percent_Identity=29.2682926829268, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787056, Length=160, Percent_Identity=31.875, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788956, Length=188, Percent_Identity=32.9787234042553, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI87081974, Length=113, Percent_Identity=34.5132743362832, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 37788; Mature: 37657

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDPTRLPPVHAPHAPPTDAPAMVLPVDDQTIVAEAVRRALVDEAGIDFHYCARSDDAM
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCE
AAAIDTRPTVILQDLVMPGTDGLTLVHAYRAHPATRDVPIIVLSTQEEPTIKRTAFAAGA
EEEECCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHCCC
NDYLVKLPDRIELIARIRYHSRSYMNLLQRDDAYRALRQSQQQLLEANLELRRLMHSDGL
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TGLSNRRYLDEYLAAEWRRGTRERAELSLLMIDVDHFKLYNDTYGHVAGDQVLRQVAATI
CCCCCCHHHHHHHHHHHHCCCHHHHEEEEEEEEECCEEEECCCCCCCHHHHHHHHHHHHH
AQCLRPSGDLAARFGGEEFAVVMPGTSAGAARLLGEKIRLAVDALRLEHGQSTAGHVTVS
HHHHCCCCCHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
IGGASIVPAPGLPTTALIEAADRALYRAKHDGRNRVEVDPPPPAR
ECCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCC
>Mature Secondary Structure 
TSDPTRLPPVHAPHAPPTDAPAMVLPVDDQTIVAEAVRRALVDEAGIDFHYCARSDDAM
CCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCE
AAAIDTRPTVILQDLVMPGTDGLTLVHAYRAHPATRDVPIIVLSTQEEPTIKRTAFAAGA
EEEECCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHCCC
NDYLVKLPDRIELIARIRYHSRSYMNLLQRDDAYRALRQSQQQLLEANLELRRLMHSDGL
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TGLSNRRYLDEYLAAEWRRGTRERAELSLLMIDVDHFKLYNDTYGHVAGDQVLRQVAATI
CCCCCCHHHHHHHHHHHHCCCHHHHEEEEEEEEECCEEEECCCCCCCHHHHHHHHHHHHH
AQCLRPSGDLAARFGGEEFAVVMPGTSAGAARLLGEKIRLAVDALRLEHGQSTAGHVTVS
HHHHCCCCCHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
IGGASIVPAPGLPTTALIEAADRALYRAKHDGRNRVEVDPPPPAR
ECCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]