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The map label for this gene is yciR [C]

Identifier: 189352742

GI number: 189352742

Start: 848449

End: 850698

Strand: Direct

Name: yciR [C]

Synonym: BMULJ_03974

Alternate gene names: 189352742

Gene position: 848449-850698 (Clockwise)

Preceding gene: 189352741

Following gene: 189352746

Centisome position: 34.31

GC content: 69.29

Gene sequence:

>2250_bases
TTGAATACCGAACCGCACAGTGCGCGCTACAGCCTCGGCCTCGCGGCGGAAGTGCTCGCGTCCGAGCAAAGCGTGCTGAA
GCTGATTACGCGCAATACGCCGCTGCCGGAACTGCTCGTCGAGGTCTGCCGGCGAGCGGAAGCGTTGCTGGGCAAGGGCG
CCGCCTGCACGATCCTGCTGCTCGACGAGGACGGCGTGCACGTACGCGTCGGCGCCGCACCGTCGCTGCCCGCGCAGTAC
GGCGCGGCGATCGACGGCGCCGCGATCGGGCCCGCGGCCGGCTCGTGCGGCACCGCGATGTACACGCGGCGCATGATCGC
CGTCGAGGACGTCGAGACCGATCCGCTGTGGGACGCATACCGGTCGATCGCGCTGCCGCTCGGGCTGCGCGCGTGCTGGT
CGGTGCCGTTCGAGGACGACACGGGCGTCGTGCTCGGCGCGTTCGCCGTCTACTACCGCACACCGCGCCGGCCGAGCGAC
GAGGAAACCGCGCTGCTGCTCGACATCAGCAACAGCGTCGGGCTCGCCGTGCATCAGGACCGCATCGCGCAGCAGCTCGC
GCGCAGCGAGGAACATCATCGGCTCGTCGTCAACAGCCTCAACGAAGGGATTCTCGTCGTGTCGCGCGACGGCGTCGTGA
TCGCGAGCAATCCGAGCGCGAACCGGATGCTGCGCGCGAAGGGCGAACTCGTCGGGCGCCGCATGTCGACGGTGATCCTG
CGCAAGCTGTCCGAGGACGGCACGCCGATCGCGCCCAGTCGTTGGCCGAGCCGGCGCGCACTGACGAGCGGCACGCCGGT
GCTCGACTACACGGTCGGCTTCGGCCTCGCCGACGGCGACGTGATCTGGGTGCGCGGCAACGCGGTGCCGATCGTGAAGC
CGGGCGACACGCAGGCCGCGTCGGTGCTCGTGTCGTTCCACGACATCGGCCCCGTGCGCGAAGCGCAGCAGCAGCTGCGC
TACCTCGCGACGCGCGATGCGCTGACGGGCCTCTACAACCGCCGCTGGCTGTCCGATCGCATGCGCGAGCTGTTCGGCGG
CCGCGATCCGGCGGGCGGCCCCGCGCGCGTCGCGATCCTGTTTCTCGATCTGGTCGGCTTCAAGAAGGTCAACGATACGG
CCGGCCACGACGCCGGCGATGCGCTGCTGCGCAGCGTCGCGGCGCGGCTCGCGGCCTGCATGCGCGGCCGGCATGCATTG
ACGCGCGTCGGCGGCGACGAGTTCGTGATTCTCGTCGACGACTGCGACGATCCCGAGGCGCTCGCAGCACTCGCGCGCGA
AGTGATCGATGCGATCGCGAAGCCGTTCGCGGTCGCGAACAACGAATACTGGCTTGGCGTGTCGATCGGCATCAGCATCG
CGCCGCGCGACGGCGACGATGCGGCGACGCTGATGCGCAACGCCGATTCCGCGATGTACGACGCGAAGCAGCGCGGGCGC
AATCACTTCACGTTCTTCACCGCGCAGCTGAACCTGCGGCTGCAGCGCCGTTTCGCGATCGAGCAGTCGTTACGGCGCGC
GCTCGCGTCGAACGCGCTGCGGCTCGCGTATCAGCCCGTCGTCGATGCGCGCACCGGCCGCACGGTCGGCGCCGAGGCGC
TGCTGCGCTGGACGAGCCCCGAACTCGGGCCGATGTCGCCGGCCGAGTTCATTCCCGTCGCCGAGGATACGGGGCTGATC
GTCGCGATCGGCCAGTGGGTGCTCGAAACCGCGTGCCGGCAGGCGGCCGAATGGCGCCGCACGATCGCGCCGGACCTGAT
GCTCGCGGTCAATCTCTCGCCGCGCCAGTTCCACGACGGGCTCGTCGAATCGGTGAGCCGCTGCCTCGCGCAGACGCGGC
TCGACCCCGGCGCGCTCGAACTCGAGATCACCGAAGGCGTGCTGATGAACGACACCGCGACGGTACTGCCGATGCTCGAG
GCGCTGACCGAGATGAACGTGCGGATCTCGGTCGACGATTTCGGCACCGGCTATTCGTCGCTCGCCTATCTGAAGCGCTT
CCCGCTGCACAACCTGAAGGTCGACCGTTCGTTCGTGTCGGGCGTGCCCGATCATCGCGACGCGGTCGCGATCACGCAGG
CGGTCGTCGCGATGGCGCATTCGCTCGGGATGAAGGTGACGGCCGAAGGCGTCGAGACCGAGGCGCAGTCGTGGTTTCTG
CAGCAGATCGGCTGCGACATGCAACAGGGCTATCTGTTCAGCCGGCCGCTCGATCCCGTCGACTACGCACGGCGTTTCGC
GCTGGCGTGA

Upstream 100 bases:

>100_bases
GGGCGCTCCGGCGCGCGGTGTGGGTCCGGGGCGAAAGCGGTACGAAAGAGCGAAAACGAATCGGGGTGTCGGCCCGGTCG
AACGGACGGCAGGATTCATC

Downstream 100 bases:

>100_bases
CGGTCGCGCGACGCACACTCAACGCGCGGGCGGCGGCGGGTCGACCTCGACGCGGTTGCGGCCGTCGTGCTTCGCACGAT
AGAGCGCGCGATCGGCGGCC

Product: signal transduction GGDEF/EAL domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 749; Mature: 749

Protein sequence:

>749_residues
MNTEPHSARYSLGLAAEVLASEQSVLKLITRNTPLPELLVEVCRRAEALLGKGAACTILLLDEDGVHVRVGAAPSLPAQY
GAAIDGAAIGPAAGSCGTAMYTRRMIAVEDVETDPLWDAYRSIALPLGLRACWSVPFEDDTGVVLGAFAVYYRTPRRPSD
EETALLLDISNSVGLAVHQDRIAQQLARSEEHHRLVVNSLNEGILVVSRDGVVIASNPSANRMLRAKGELVGRRMSTVIL
RKLSEDGTPIAPSRWPSRRALTSGTPVLDYTVGFGLADGDVIWVRGNAVPIVKPGDTQAASVLVSFHDIGPVREAQQQLR
YLATRDALTGLYNRRWLSDRMRELFGGRDPAGGPARVAILFLDLVGFKKVNDTAGHDAGDALLRSVAARLAACMRGRHAL
TRVGGDEFVILVDDCDDPEALAALAREVIDAIAKPFAVANNEYWLGVSIGISIAPRDGDDAATLMRNADSAMYDAKQRGR
NHFTFFTAQLNLRLQRRFAIEQSLRRALASNALRLAYQPVVDARTGRTVGAEALLRWTSPELGPMSPAEFIPVAEDTGLI
VAIGQWVLETACRQAAEWRRTIAPDLMLAVNLSPRQFHDGLVESVSRCLAQTRLDPGALELEITEGVLMNDTATVLPMLE
ALTEMNVRISVDDFGTGYSSLAYLKRFPLHNLKVDRSFVSGVPDHRDAVAITQAVVAMAHSLGMKVTAEGVETEAQSWFL
QQIGCDMQQGYLFSRPLDPVDYARRFALA

Sequences:

>Translated_749_residues
MNTEPHSARYSLGLAAEVLASEQSVLKLITRNTPLPELLVEVCRRAEALLGKGAACTILLLDEDGVHVRVGAAPSLPAQY
GAAIDGAAIGPAAGSCGTAMYTRRMIAVEDVETDPLWDAYRSIALPLGLRACWSVPFEDDTGVVLGAFAVYYRTPRRPSD
EETALLLDISNSVGLAVHQDRIAQQLARSEEHHRLVVNSLNEGILVVSRDGVVIASNPSANRMLRAKGELVGRRMSTVIL
RKLSEDGTPIAPSRWPSRRALTSGTPVLDYTVGFGLADGDVIWVRGNAVPIVKPGDTQAASVLVSFHDIGPVREAQQQLR
YLATRDALTGLYNRRWLSDRMRELFGGRDPAGGPARVAILFLDLVGFKKVNDTAGHDAGDALLRSVAARLAACMRGRHAL
TRVGGDEFVILVDDCDDPEALAALAREVIDAIAKPFAVANNEYWLGVSIGISIAPRDGDDAATLMRNADSAMYDAKQRGR
NHFTFFTAQLNLRLQRRFAIEQSLRRALASNALRLAYQPVVDARTGRTVGAEALLRWTSPELGPMSPAEFIPVAEDTGLI
VAIGQWVLETACRQAAEWRRTIAPDLMLAVNLSPRQFHDGLVESVSRCLAQTRLDPGALELEITEGVLMNDTATVLPMLE
ALTEMNVRISVDDFGTGYSSLAYLKRFPLHNLKVDRSFVSGVPDHRDAVAITQAVVAMAHSLGMKVTAEGVETEAQSWFL
QQIGCDMQQGYLFSRPLDPVDYARRFALA
>Mature_749_residues
MNTEPHSARYSLGLAAEVLASEQSVLKLITRNTPLPELLVEVCRRAEALLGKGAACTILLLDEDGVHVRVGAAPSLPAQY
GAAIDGAAIGPAAGSCGTAMYTRRMIAVEDVETDPLWDAYRSIALPLGLRACWSVPFEDDTGVVLGAFAVYYRTPRRPSD
EETALLLDISNSVGLAVHQDRIAQQLARSEEHHRLVVNSLNEGILVVSRDGVVIASNPSANRMLRAKGELVGRRMSTVIL
RKLSEDGTPIAPSRWPSRRALTSGTPVLDYTVGFGLADGDVIWVRGNAVPIVKPGDTQAASVLVSFHDIGPVREAQQQLR
YLATRDALTGLYNRRWLSDRMRELFGGRDPAGGPARVAILFLDLVGFKKVNDTAGHDAGDALLRSVAARLAACMRGRHAL
TRVGGDEFVILVDDCDDPEALAALAREVIDAIAKPFAVANNEYWLGVSIGISIAPRDGDDAATLMRNADSAMYDAKQRGR
NHFTFFTAQLNLRLQRRFAIEQSLRRALASNALRLAYQPVVDARTGRTVGAEALLRWTSPELGPMSPAEFIPVAEDTGLI
VAIGQWVLETACRQAAEWRRTIAPDLMLAVNLSPRQFHDGLVESVSRCLAQTRLDPGALELEITEGVLMNDTATVLPMLE
ALTEMNVRISVDDFGTGYSSLAYLKRFPLHNLKVDRSFVSGVPDHRDAVAITQAVVAMAHSLGMKVTAEGVETEAQSWFL
QQIGCDMQQGYLFSRPLDPVDYARRFALA

Specific function: Unknown

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=446, Percent_Identity=36.322869955157, Blast_Score=304, Evalue=1e-83,
Organism=Escherichia coli, GI87081921, Length=425, Percent_Identity=34.5882352941176, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI226510982, Length=389, Percent_Identity=32.6478149100257, Blast_Score=192, Evalue=6e-50,
Organism=Escherichia coli, GI1790496, Length=246, Percent_Identity=36.1788617886179, Blast_Score=171, Evalue=2e-43,
Organism=Escherichia coli, GI1787055, Length=393, Percent_Identity=27.735368956743, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1788502, Length=245, Percent_Identity=35.5102040816327, Blast_Score=146, Evalue=5e-36,
Organism=Escherichia coli, GI87081845, Length=256, Percent_Identity=35.9375, Blast_Score=146, Evalue=5e-36,
Organism=Escherichia coli, GI87081743, Length=262, Percent_Identity=32.824427480916, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI87081980, Length=254, Percent_Identity=30.3149606299213, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI1786507, Length=237, Percent_Identity=30.379746835443, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788381, Length=578, Percent_Identity=26.1245674740484, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1788849, Length=249, Percent_Identity=32.5301204819277, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI87082096, Length=245, Percent_Identity=28.1632653061224, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI145693134, Length=184, Percent_Identity=32.6086956521739, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1786584, Length=185, Percent_Identity=29.7297297297297, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI87081881, Length=280, Percent_Identity=29.2857142857143, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1787262, Length=189, Percent_Identity=30.1587301587302, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1787816, Length=170, Percent_Identity=35.8823529411765, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87081977, Length=173, Percent_Identity=29.4797687861272, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788956, Length=162, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI87082007, Length=168, Percent_Identity=32.7380952380952, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787802, Length=185, Percent_Identity=26.4864864864865, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1787410, Length=233, Percent_Identity=24.8927038626609, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 81371; Mature: 81371

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTEPHSARYSLGLAAEVLASEQSVLKLITRNTPLPELLVEVCRRAEALLGKGAACTILL
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEE
LDEDGVHVRVGAAPSLPAQYGAAIDGAAIGPAAGSCGTAMYTRRMIAVEDVETDPLWDAY
ECCCCCEEEECCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHEEEEECCCCCCHHHHH
RSIALPLGLRACWSVPFEDDTGVVLGAFAVYYRTPRRPSDEETALLLDISNSVGLAVHQD
HHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEHHH
RIAQQLARSEEHHRLVVNSLNEGILVVSRDGVVIASNPSANRMLRAKGELVGRRMSTVIL
HHHHHHHCCCCCCCCEEECCCCCEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
RKLSEDGTPIAPSRWPSRRALTSGTPVLDYTVGFGLADGDVIWVRGNAVPIVKPGDTQAA
HHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCEEEEECCCCCHHH
SVLVSFHDIGPVREAQQQLRYLATRDALTGLYNRRWLSDRMRELFGGRDPAGGPARVAIL
HEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
FLDLVGFKKVNDTAGHDAGDALLRSVAARLAACMRGRHALTRVGGDEFVILVDDCDDPEA
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEEEECCCCHHH
LAALAREVIDAIAKPFAVANNEYWLGVSIGISIAPRDGDDAATLMRNADSAMYDAKQRGR
HHHHHHHHHHHHHCCCEECCCCEEEEEEEEEEEECCCCCHHHHHHHCCCHHHHHHHHCCC
NHFTFFTAQLNLRLQRRFAIEQSLRRALASNALRLAYQPVVDARTGRTVGAEALLRWTSP
CEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCCCCHHHHHEECCC
ELGPMSPAEFIPVAEDTGLIVAIGQWVLETACRQAAEWRRTIAPDLMLAVNLSPRQFHDG
CCCCCCCHHEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHH
LVESVSRCLAQTRLDPGALELEITEGVLMNDTATVLPMLEALTEMNVRISVDDFGTGYSS
HHHHHHHHHHHHCCCCCCEEEEEECCEEECCHHHHHHHHHHHHHCCEEEEECCCCCCHHH
LAYLKRFPLHNLKVDRSFVSGVPDHRDAVAITQAVVAMAHSLGMKVTAEGVETEAQSWFL
HHHHHHCCCCCCEECHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHH
QQIGCDMQQGYLFSRPLDPVDYARRFALA
HHHCCCHHCCEEECCCCCHHHHHHHHCCC
>Mature Secondary Structure
MNTEPHSARYSLGLAAEVLASEQSVLKLITRNTPLPELLVEVCRRAEALLGKGAACTILL
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEE
LDEDGVHVRVGAAPSLPAQYGAAIDGAAIGPAAGSCGTAMYTRRMIAVEDVETDPLWDAY
ECCCCCEEEECCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHEEEEECCCCCCHHHHH
RSIALPLGLRACWSVPFEDDTGVVLGAFAVYYRTPRRPSDEETALLLDISNSVGLAVHQD
HHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEHHH
RIAQQLARSEEHHRLVVNSLNEGILVVSRDGVVIASNPSANRMLRAKGELVGRRMSTVIL
HHHHHHHCCCCCCCCEEECCCCCEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
RKLSEDGTPIAPSRWPSRRALTSGTPVLDYTVGFGLADGDVIWVRGNAVPIVKPGDTQAA
HHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCEEEEECCCCCHHH
SVLVSFHDIGPVREAQQQLRYLATRDALTGLYNRRWLSDRMRELFGGRDPAGGPARVAIL
HEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
FLDLVGFKKVNDTAGHDAGDALLRSVAARLAACMRGRHALTRVGGDEFVILVDDCDDPEA
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEEEECCCCHHH
LAALAREVIDAIAKPFAVANNEYWLGVSIGISIAPRDGDDAATLMRNADSAMYDAKQRGR
HHHHHHHHHHHHHCCCEECCCCEEEEEEEEEEEECCCCCHHHHHHHCCCHHHHHHHHCCC
NHFTFFTAQLNLRLQRRFAIEQSLRRALASNALRLAYQPVVDARTGRTVGAEALLRWTSP
CEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCCCCHHHHHEECCC
ELGPMSPAEFIPVAEDTGLIVAIGQWVLETACRQAAEWRRTIAPDLMLAVNLSPRQFHDG
CCCCCCCHHEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHH
LVESVSRCLAQTRLDPGALELEITEGVLMNDTATVLPMLEALTEMNVRISVDDFGTGYSS
HHHHHHHHHHHHCCCCCCEEEEEECCEEECCHHHHHHHHHHHHHCCEEEEECCCCCCHHH
LAYLKRFPLHNLKVDRSFVSGVPDHRDAVAITQAVVAMAHSLGMKVTAEGVETEAQSWFL
HHHHHHCCCCCCEECHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHH
QQIGCDMQQGYLFSRPLDPVDYARRFALA
HHHCCCHHCCEEECCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]