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The map label for this gene is coxS [H]

Identifier: 189352732

GI number: 189352732

Start: 836623

End: 837126

Strand: Direct

Name: coxS [H]

Synonym: BMULJ_03964

Alternate gene names: 189352732

Gene position: 836623-837126 (Clockwise)

Preceding gene: 189352731

Following gene: 189352733

Centisome position: 33.83

GC content: 71.03

Gene sequence:

>504_bases
ATGTCCCATTCCGCTTCCGCGCCGCGGCCGCTCGCGTTTCGCGTCAACGGCGTGCCGCACCGCTTCGACGCCGCCGCCCC
CGATACGCCGCTGCTGCTGGTCCTGCGCAACGACTGCGCGCTGAACGGCCCGAAATACGGCTGCGGACTCGGTCAGTGCG
GCGCGTGCACGGTACTGATCGACGGGCAGCCGGCGCGCGCCTGCGTGCTGCCGGCGGCGGCCGCATCGGGGCGCGACGTG
ACGACGCTCGAAGGGCTCGGCTCGCGCGATGCGCCGCATCCGGTCCAGCGCGCGTTCATCGACGAGCAGGCCGCGCAATG
CGGCTATTGCCTGAACGGGATGATCATGAGCACGAAGGCGCTGCTCGACCGCAACCCGACGCCGGACGACGCGGCGATCC
GCGAGGCGCTGCGCTTCAATCTGTGCCGCTGCGGCACGCATCTGGAGATCGTTCGCGCGGTGCATCGCGCGGCACGCTAT
GTGCGGAGCGACGATGCAGCGTGA

Upstream 100 bases:

>100_bases
GCGCGCCGGCGATCGGCGTCGCCGCGCGCCGGTCTGCGCCGGCCGCCGGCCATGCCTGCCGTCGGTTGACGTTCGCCCGC
ACCCGCTTCCGGATCTGCCC

Downstream 100 bases:

>100_bases
TCCGAACCTGCCGGCACGCGCGCGCGCCGCGCAGGACGCGCTCGAGTCGCGCGATGCGTCGGGCGCGGACGACGCCGGCC
TGCGCTCGCATCGTGCGCGC

Product: aerobic-type carbon monoxide dehydrogenase small subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MSHSASAPRPLAFRVNGVPHRFDAAAPDTPLLLVLRNDCALNGPKYGCGLGQCGACTVLIDGQPARACVLPAAAASGRDV
TTLEGLGSRDAPHPVQRAFIDEQAAQCGYCLNGMIMSTKALLDRNPTPDDAAIREALRFNLCRCGTHLEIVRAVHRAARY
VRSDDAA

Sequences:

>Translated_167_residues
MSHSASAPRPLAFRVNGVPHRFDAAAPDTPLLLVLRNDCALNGPKYGCGLGQCGACTVLIDGQPARACVLPAAAASGRDV
TTLEGLGSRDAPHPVQRAFIDEQAAQCGYCLNGMIMSTKALLDRNPTPDDAAIREALRFNLCRCGTHLEIVRAVHRAARY
VRSDDAA
>Mature_166_residues
SHSASAPRPLAFRVNGVPHRFDAAAPDTPLLLVLRNDCALNGPKYGCGLGQCGACTVLIDGQPARACVLPAAAASGRDVT
TLEGLGSRDAPHPVQRAFIDEQAAQCGYCLNGMIMSTKALLDRNPTPDDAAIREALRFNLCRCGTHLEIVRAVHRAARYV
RSDDAA

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=160, Percent_Identity=38.125, Blast_Score=78, Evalue=4e-15,
Organism=Homo sapiens, GI71773480, Length=98, Percent_Identity=40.8163265306122, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1786480, Length=169, Percent_Identity=40.8284023668639, Blast_Score=117, Evalue=3e-28,
Organism=Escherichia coli, GI1789232, Length=156, Percent_Identity=40.3846153846154, Blast_Score=102, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17539860, Length=158, Percent_Identity=36.7088607594937, Blast_Score=107, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17540638, Length=158, Percent_Identity=37.3417721518987, Blast_Score=106, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI32566215, Length=153, Percent_Identity=37.9084967320261, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI17737937, Length=145, Percent_Identity=37.9310344827586, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24647197, Length=162, Percent_Identity=30.8641975308642, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24647195, Length=162, Percent_Identity=30.8641975308642, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24647199, Length=154, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 17706; Mature: 17575

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
5.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHSASAPRPLAFRVNGVPHRFDAAAPDTPLLLVLRNDCALNGPKYGCGLGQCGACTVLI
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEE
DGQPARACVLPAAAASGRDVTTLEGLGSRDAPHPVQRAFIDEQAAQCGYCLNGMIMSTKA
CCCCCCEEEEECCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
LLDRNPTPDDAAIREALRFNLCRCGTHLEIVRAVHRAARYVRSDDAA
HHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SHSASAPRPLAFRVNGVPHRFDAAAPDTPLLLVLRNDCALNGPKYGCGLGQCGACTVLI
CCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEE
DGQPARACVLPAAAASGRDVTTLEGLGSRDAPHPVQRAFIDEQAAQCGYCLNGMIMSTKA
CCCCCCEEEEECCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
LLDRNPTPDDAAIREALRFNLCRCGTHLEIVRAVHRAARYVRSDDAA
HHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]