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The map label for this gene is tauD [C]

Identifier: 189352712

GI number: 189352712

Start: 815376

End: 816320

Strand: Reverse

Name: tauD [C]

Synonym: BMULJ_03944

Alternate gene names: 189352712

Gene position: 816320-815376 (Counterclockwise)

Preceding gene: 189352713

Following gene: 189352711

Centisome position: 33.01

GC content: 68.04

Gene sequence:

>945_bases
ATGTCCGAAGTCCAGCACGCCGCTCACCCGTCATCGCACGCCGCGCCGCGCACGGCCGCTGCCCCGCTCCAGCTTCGTCA
GGTCGCCGGCCGGATCGGCGCCGAAATCTCCGGCGTGCGGCTATCGGCCACGCTCGACGATGCGACATTCGACGCGATCC
AGGCCGCGCTGCTGCGCCACAAGGTACTGTTCTTCCGCGGCCAGCATCATCTCGACGATGCCGCGCAGGAAGCGTTCGCG
CGCCGTTTCGGCGACACCGTCGCGCATCCGACCGTGCCGTCCGTCGACGGCAGCGCGCATCTGCTCGAACTCGATTCCGC
GCACGGCGCGCGCGCCAACTCGTGGCACACCGACGTGACCTTCGTCGACGCGTATCCGAAGATCTCGATCCTGCGCGCCG
TCGTGATCCCGCCCGTCGGCGGCGACACGGTGTGGGCCAACACGGCCGCCGCGTATGCGCATCTGCCCGACACGCTGCGC
ACGCTCGCCGATACGCTGTGGGCCGTCCATACGAACGCGTACGACTACGCGTCGACGCACGTGCACGCCGACGAAACGCA
GTTGAAGCGCTACCGCGAAGTATTCACCTCGACCGTCTACGAGACCGAGCACCCGGTCGTGCGCGTGCATCCCGAAACGG
GCGAGCGCACGCTCGTGCTCGGCCACTTCGTGCAGCGGATCAAGGGTCTGTCGACGCAGGATTCCGCGCATCTGCTGCAG
GTTTTCCACGAACATGTGACGCGCCTCGAGAACACCGTGCGCTGGAGCTGGCAGGAAGGCGACGTCGCGATCTGGGACAA
CCGCGCGACGCAGCATTACGCGATCAACGACTACGGCGATGCGCGCCGCGTCGTGCGGCGTGCGACGGTTCACGGCGACG
TGCCGGTCGGCATCGACGGCCGGCAAAGCGTCGTGCTGAAAGGGCCGGGCGCCACGCTGCAGTAA

Upstream 100 bases:

>100_bases
TCGCATCCGCACGCTAAGGTTGTGACGATTGATCGGTTCCGGTTCCGCGCGGTCCCTGCTTGAATGGAAACCTGCACGTC
CTCACCTCAGGAGACTCCCG

Downstream 100 bases:

>100_bases
TGCAGTAACGCGTGTCGCGCGGGCGAGAACGGCGATGCGTCGCCGTCCGCGCCTGCGCGGCGGCCCGTGCCGCGTGACAG
GAAACCCGACCATGCATCCT

Product: taurine dioxygenase

Products: Aminoacetaldehyde; CO2; H+; Sulfite; Succinate [C]

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSEVQHAAHPSSHAAPRTAAAPLQLRQVAGRIGAEISGVRLSATLDDATFDAIQAALLRHKVLFFRGQHHLDDAAQEAFA
RRFGDTVAHPTVPSVDGSAHLLELDSAHGARANSWHTDVTFVDAYPKISILRAVVIPPVGGDTVWANTAAAYAHLPDTLR
TLADTLWAVHTNAYDYASTHVHADETQLKRYREVFTSTVYETEHPVVRVHPETGERTLVLGHFVQRIKGLSTQDSAHLLQ
VFHEHVTRLENTVRWSWQEGDVAIWDNRATQHYAINDYGDARRVVRRATVHGDVPVGIDGRQSVVLKGPGATLQ

Sequences:

>Translated_314_residues
MSEVQHAAHPSSHAAPRTAAAPLQLRQVAGRIGAEISGVRLSATLDDATFDAIQAALLRHKVLFFRGQHHLDDAAQEAFA
RRFGDTVAHPTVPSVDGSAHLLELDSAHGARANSWHTDVTFVDAYPKISILRAVVIPPVGGDTVWANTAAAYAHLPDTLR
TLADTLWAVHTNAYDYASTHVHADETQLKRYREVFTSTVYETEHPVVRVHPETGERTLVLGHFVQRIKGLSTQDSAHLLQ
VFHEHVTRLENTVRWSWQEGDVAIWDNRATQHYAINDYGDARRVVRRATVHGDVPVGIDGRQSVVLKGPGATLQ
>Mature_313_residues
SEVQHAAHPSSHAAPRTAAAPLQLRQVAGRIGAEISGVRLSATLDDATFDAIQAALLRHKVLFFRGQHHLDDAAQEAFAR
RFGDTVAHPTVPSVDGSAHLLELDSAHGARANSWHTDVTFVDAYPKISILRAVVIPPVGGDTVWANTAAAYAHLPDTLRT
LADTLWAVHTNAYDYASTHVHADETQLKRYREVFTSTVYETEHPVVRVHPETGERTLVLGHFVQRIKGLSTQDSAHLLQV
FHEHVTRLENTVRWSWQEGDVAIWDNRATQHYAINDYGDARRVVRRATVHGDVPVGIDGRQSVVLKGPGATLQ

Specific function: Catalyzes The Conversion Of Taurine And Alpha Ketoglutarate To Sulfite, Aminoacetaldehyde And Succinate. Required For The Utilization Of Taurine (2-Aminoethanesulfonic Acid) As An Alternative Sulfur Source. Pentane-Sulfonic Acid, 3- (N-Morpholino)Propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=276, Percent_Identity=38.768115942029, Blast_Score=186, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6322971, Length=294, Percent_Identity=28.9115646258503, Blast_Score=97, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: 1.14.11.17 [C]

Molecular weight: Translated: 34578; Mature: 34447

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVQHAAHPSSHAAPRTAAAPLQLRQVAGRIGAEISGVRLSATLDDATFDAIQAALLRH
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHH
KVLFFRGQHHLDDAAQEAFARRFGDTVAHPTVPSVDGSAHLLELDSAHGARANSWHTDVT
HHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEE
FVDAYPKISILRAVVIPPVGGDTVWANTAAAYAHLPDTLRTLADTLWAVHTNAYDYASTH
EEECCCCHHEEHHEEECCCCCCCEECCCHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCE
VHADETQLKRYREVFTSTVYETEHPVVRVHPETGERTLVLGHFVQRIKGLSTQDSAHLLQ
EECCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEHHHHHHHHHHCCCCCCHHHHHH
VFHEHVTRLENTVRWSWQEGDVAIWDNRATQHYAINDYGDARRVVRRATVHGDVPVGIDG
HHHHHHHHHHHHEEEEECCCCEEEECCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCC
RQSVVLKGPGATLQ
CCEEEEECCCCCCC
>Mature Secondary Structure 
SEVQHAAHPSSHAAPRTAAAPLQLRQVAGRIGAEISGVRLSATLDDATFDAIQAALLRH
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHH
KVLFFRGQHHLDDAAQEAFARRFGDTVAHPTVPSVDGSAHLLELDSAHGARANSWHTDVT
HHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEE
FVDAYPKISILRAVVIPPVGGDTVWANTAAAYAHLPDTLRTLADTLWAVHTNAYDYASTH
EEECCCCHHEEHHEEECCCCCCCEECCCHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCE
VHADETQLKRYREVFTSTVYETEHPVVRVHPETGERTLVLGHFVQRIKGLSTQDSAHLLQ
EECCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEHHHHHHHHHHCCCCCCHHHHHH
VFHEHVTRLENTVRWSWQEGDVAIWDNRATQHYAINDYGDARRVVRRATVHGDVPVGIDG
HHHHHHHHHHHHEEEEECCCCEEEECCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCC
RQSVVLKGPGATLQ
CCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Ascorbate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; O2; Taurine [C]

Specific reaction: 2-Oxoglutarate + O2 + Taurine --> Aminoacetaldehyde + CO2 + H+ + Sulfite + Succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]