Click here to switch to the map view.

The map label for this gene is dppA [H]

Identifier: 189352710

GI number: 189352710

Start: 812520

End: 814181

Strand: Direct

Name: dppA [H]

Synonym: BMULJ_03942

Alternate gene names: 189352710

Gene position: 812520-814181 (Clockwise)

Preceding gene: 189352707

Following gene: 189352717

Centisome position: 32.85

GC content: 67.27

Gene sequence:

>1662_bases
ATGAACATCCGCTTGATTTCGCCCGCCGCGCGTCGCGCGCGCCACGTGTCGCCGTTCGCGAGCGCGCTTCGCTGCCTCGC
CGCGTCGCTGATGCTGGCCGGGGCCGCGACGCCCGCGCTTGCTGCACCGGCCGGCAACACGCTCGTGTTCTGCAGCGAAG
GCAGCCCGGCCGGTTTCGATCCGGGCCAGCACACGACGAGCACCGATTTCGACGCGAGTACGCATACGGTCTACAACGAA
CTCGTGCAGTTCCGGCGCGGCACGCTCGACCTCGAGCCGGCGCTGGCGACGAGCTGGGACGTGTCGGCCGACCAGCGCGT
CTACACGTTCCACCTGCGGCGCGGCGTGAAATTCCAGACGACCGCATGGTTCAAGCCGACTCGCCCGTTCCAGGCCGACG
ACGTGGTCTTCACGTTCCGCCGGATGCTCGATCGCGACGATCCGTTCCGCAAGGCGTATCCGGTCAGCTTTCCGTACTTC
AGCGACCTCGGCTTCGATCGCAATATCGAGCGCATCGAAAAGGTCGACGACTACACGGTGCGCTTCGCGCTGAAAGAGCC
CGACGTCGTGTTCGTGCGCAATCTCGCGATGGCCTTCGCGTCGATCCTGTCGGCCGAGTATGCGTCGCAGCTCGCCGCGC
GCCATCGCGAAGCCGACATCAACCAGTTTCCGGTCGGCACGGGCCCGTTCCAGTTGCGCGCGTATCAGAAGGACGCGGTG
ATTCGCTACGACGCGAATCCCGACTACTGGAAGCCCGACGACGTGAAGCTCGCGCATCTGGTGTTCTCGATCACGCCCGA
TCCGGCGACGCGCCTGCGCAAGCTGACGGGCGGCGAGTGCCAGGTGTCGGTATTCCCGCGCCCGGCCGATCTCGACACGG
TGCGGCGCAACCCGTCGCTCACGCTGTTCTCGGCAACGGGGTTCAACGTCGGCTTCGTCGCGTACAACACGCAGCATCCG
CCGCTCGATCGCGTCGAGGTGCGGCGCGCGCTCGACATGGCGATCGACAAGGCCGCGATCCTGAAGACGGTCTTCAACGG
CGACGCGACGATCGCGACGAACCCGATGCCGCCCGCGCAATGGTCGTACAACCCGCGCCTCAAGGATGCGCCGCACGATC
CGGCCGCCGCGAAGGCGCTGCTCGCGCGCGCGGGATTCCCGAACGGCTTCGACCTGACGCTGTGGGCGATGCCCGTGCAG
CGTCCGTACAACCCGAACGCGCAGCTGATGGCGCAGCTGATCCAGCAGGACTGGGCGAAGATCGGCGTGCGCGCGAAGAT
CGTCAGCTACGAGTGGGGCGAATACAACCGGCGCGCGAAGCAGGACGGCCAGCACGACGCGATCCTGTACGGCTGGTCGG
GCGACAACGGCGATCCCGACAACTGGCTCGGCGCGCTGCTCGGCTGCGACGCCGTGCACGGCAGCAATCTCGCGAAGTGG
TGCAACGCGGATTTCGAGCGGCTCGTCGACGCGGCGCGCACGAATGCCGACGTCGCGAAGCGCACGGCGCTGTACGAGCA
GGCGCAGGTCGTGTTCAAGGATCAGGTGCCGTTCACGCCGATCGCGACGTCGATCGTGTCGCTGCCGGTGTCGAAGCGTG
TGCACGGGCTCGTGTTTTCGCCGCTCGGCGGGCATCGGTTCGACGGCGTGTGGCTCGAGTGA

Upstream 100 bases:

>100_bases
ATCGCGATAAGCAATGGCGAATCGATTGGTTCGCGATCGGCGGGACAGGCGCGAAGATCGTCCGTCTTCATTCGTATGAA
CGCCATCCGCTTCGATCGCC

Downstream 100 bases:

>100_bases
CGCGCAGCGGCGCAGCGAATCGCCGTGCTGACGACGACGGACCGGCGTGCCGGTCCGTGCGCGCGCGACGCGTCAGTTGA
GCGCGACCGCCGCCGCGGCT

Product: peptide/nickel transport system substrate-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MNIRLISPAARRARHVSPFASALRCLAASLMLAGAATPALAAPAGNTLVFCSEGSPAGFDPGQHTTSTDFDASTHTVYNE
LVQFRRGTLDLEPALATSWDVSADQRVYTFHLRRGVKFQTTAWFKPTRPFQADDVVFTFRRMLDRDDPFRKAYPVSFPYF
SDLGFDRNIERIEKVDDYTVRFALKEPDVVFVRNLAMAFASILSAEYASQLAARHREADINQFPVGTGPFQLRAYQKDAV
IRYDANPDYWKPDDVKLAHLVFSITPDPATRLRKLTGGECQVSVFPRPADLDTVRRNPSLTLFSATGFNVGFVAYNTQHP
PLDRVEVRRALDMAIDKAAILKTVFNGDATIATNPMPPAQWSYNPRLKDAPHDPAAAKALLARAGFPNGFDLTLWAMPVQ
RPYNPNAQLMAQLIQQDWAKIGVRAKIVSYEWGEYNRRAKQDGQHDAILYGWSGDNGDPDNWLGALLGCDAVHGSNLAKW
CNADFERLVDAARTNADVAKRTALYEQAQVVFKDQVPFTPIATSIVSLPVSKRVHGLVFSPLGGHRFDGVWLE

Sequences:

>Translated_553_residues
MNIRLISPAARRARHVSPFASALRCLAASLMLAGAATPALAAPAGNTLVFCSEGSPAGFDPGQHTTSTDFDASTHTVYNE
LVQFRRGTLDLEPALATSWDVSADQRVYTFHLRRGVKFQTTAWFKPTRPFQADDVVFTFRRMLDRDDPFRKAYPVSFPYF
SDLGFDRNIERIEKVDDYTVRFALKEPDVVFVRNLAMAFASILSAEYASQLAARHREADINQFPVGTGPFQLRAYQKDAV
IRYDANPDYWKPDDVKLAHLVFSITPDPATRLRKLTGGECQVSVFPRPADLDTVRRNPSLTLFSATGFNVGFVAYNTQHP
PLDRVEVRRALDMAIDKAAILKTVFNGDATIATNPMPPAQWSYNPRLKDAPHDPAAAKALLARAGFPNGFDLTLWAMPVQ
RPYNPNAQLMAQLIQQDWAKIGVRAKIVSYEWGEYNRRAKQDGQHDAILYGWSGDNGDPDNWLGALLGCDAVHGSNLAKW
CNADFERLVDAARTNADVAKRTALYEQAQVVFKDQVPFTPIATSIVSLPVSKRVHGLVFSPLGGHRFDGVWLE
>Mature_553_residues
MNIRLISPAARRARHVSPFASALRCLAASLMLAGAATPALAAPAGNTLVFCSEGSPAGFDPGQHTTSTDFDASTHTVYNE
LVQFRRGTLDLEPALATSWDVSADQRVYTFHLRRGVKFQTTAWFKPTRPFQADDVVFTFRRMLDRDDPFRKAYPVSFPYF
SDLGFDRNIERIEKVDDYTVRFALKEPDVVFVRNLAMAFASILSAEYASQLAARHREADINQFPVGTGPFQLRAYQKDAV
IRYDANPDYWKPDDVKLAHLVFSITPDPATRLRKLTGGECQVSVFPRPADLDTVRRNPSLTLFSATGFNVGFVAYNTQHP
PLDRVEVRRALDMAIDKAAILKTVFNGDATIATNPMPPAQWSYNPRLKDAPHDPAAAKALLARAGFPNGFDLTLWAMPVQ
RPYNPNAQLMAQLIQQDWAKIGVRAKIVSYEWGEYNRRAKQDGQHDAILYGWSGDNGDPDNWLGALLGCDAVHGSNLAKW
CNADFERLVDAARTNADVAKRTALYEQAQVVFKDQVPFTPIATSIVSLPVSKRVHGLVFSPLGGHRFDGVWLE

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=527, Percent_Identity=49.7153700189753, Blast_Score=524, Evalue=1e-150,
Organism=Escherichia coli, GI1787551, Length=540, Percent_Identity=35.5555555555556, Blast_Score=341, Evalue=8e-95,
Organism=Escherichia coli, GI1787052, Length=468, Percent_Identity=28.8461538461538, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1787762, Length=535, Percent_Identity=24.6728971962617, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1789887, Length=548, Percent_Identity=25, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87081878, Length=533, Percent_Identity=25.328330206379, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1787495, Length=543, Percent_Identity=24.8618784530387, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1789397, Length=452, Percent_Identity=24.3362831858407, Blast_Score=99, Evalue=9e-22,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 61536; Mature: 61536

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRLISPAARRARHVSPFASALRCLAASLMLAGAATPALAAPAGNTLVFCSEGSPAGFD
CCEEEECHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCC
PGQHTTSTDFDASTHTVYNELVQFRRGTLDLEPALATSWDVSADQRVYTFHLRRGVKFQT
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEE
TAWFKPTRPFQADDVVFTFRRMLDRDDPFRKAYPVSFPYFSDLGFDRNIERIEKVDDYTV
EEEECCCCCCCCCHHHHHHHHHHCCCCCCHHCCCCCCCCHHCCCCCCCHHHHHHCCCEEE
RFALKEPDVVFVRNLAMAFASILSAEYASQLAARHREADINQFPVGTGPFQLRAYQKDAV
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEE
IRYDANPDYWKPDDVKLAHLVFSITPDPATRLRKLTGGECQVSVFPRPADLDTVRRNPSL
EEECCCCCCCCCCCCEEEEEEEEECCCHHHHHHHCCCCCEEEEECCCCCCHHHHCCCCCE
TLFSATGFNVGFVAYNTQHPPLDRVEVRRALDMAIDKAAILKTVFNGDATIATNPMPPAQ
EEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
WSYNPRLKDAPHDPAAAKALLARAGFPNGFDLTLWAMPVQRPYNPNAQLMAQLIQQDWAK
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHH
IGVRAKIVSYEWGEYNRRAKQDGQHDAILYGWSGDNGDPDNWLGALLGCDAVHGSNLAKW
HCCEEEEEEEECCCHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHH
CNADFERLVDAARTNADVAKRTALYEQAQVVFKDQVPFTPIATSIVSLPVSKRVHGLVFS
HCHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHCCHHHHHCEEEEC
PLGGHRFDGVWLE
CCCCCCCCCEECC
>Mature Secondary Structure
MNIRLISPAARRARHVSPFASALRCLAASLMLAGAATPALAAPAGNTLVFCSEGSPAGFD
CCEEEECHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCC
PGQHTTSTDFDASTHTVYNELVQFRRGTLDLEPALATSWDVSADQRVYTFHLRRGVKFQT
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEE
TAWFKPTRPFQADDVVFTFRRMLDRDDPFRKAYPVSFPYFSDLGFDRNIERIEKVDDYTV
EEEECCCCCCCCCHHHHHHHHHHCCCCCCHHCCCCCCCCHHCCCCCCCHHHHHHCCCEEE
RFALKEPDVVFVRNLAMAFASILSAEYASQLAARHREADINQFPVGTGPFQLRAYQKDAV
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEE
IRYDANPDYWKPDDVKLAHLVFSITPDPATRLRKLTGGECQVSVFPRPADLDTVRRNPSL
EEECCCCCCCCCCCCEEEEEEEEECCCHHHHHHHCCCCCEEEEECCCCCCHHHHCCCCCE
TLFSATGFNVGFVAYNTQHPPLDRVEVRRALDMAIDKAAILKTVFNGDATIATNPMPPAQ
EEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
WSYNPRLKDAPHDPAAAKALLARAGFPNGFDLTLWAMPVQRPYNPNAQLMAQLIQQDWAK
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHH
IGVRAKIVSYEWGEYNRRAKQDGQHDAILYGWSGDNGDPDNWLGALLGCDAVHGSNLAKW
HCCEEEEEEEECCCHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHH
CNADFERLVDAARTNADVAKRTALYEQAQVVFKDQVPFTPIATSIVSLPVSKRVHGLVFS
HCHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHCCHHHHHCEEEEC
PLGGHRFDGVWLE
CCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]