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The map label for this gene is adh [H]

Identifier: 189352705

GI number: 189352705

Start: 807424

End: 808581

Strand: Direct

Name: adh [H]

Synonym: BMULJ_03937

Alternate gene names: 189352705

Gene position: 807424-808581 (Clockwise)

Preceding gene: 189352704

Following gene: 189352707

Centisome position: 32.65

GC content: 70.73

Gene sequence:

>1158_bases
ATGAACCCGTTTCAATTCCGCACCGTCCCGACGCTGATCGTCGAATACGGCGCCGCGCGCCGGCTCGGCGCGCTGCTGCG
CGCGCGCTTTCCGACGCTCGCGCGCCTGTGCGTGGTGACCGACGCGTTCCTGCACCGCAGCGGCGTGCTCGCGCCCGCGC
TCGACAGCCTCGCCGCGCACGGCTGGCAGGTGACCGTGATCGACGACGTGATCGCCGATCCGCCCGAGCGCGTCGTGCTC
GACGCGACGGCGCGCGCGGTCGCGGCCGATGCGCAAATCGTGCTGGGTCTCGGCGGCGGTTCGTCGATGGACGTCGCGAA
GCTGATCGCCGTGCTCGCGCCGGGCCGGCAGCCGCTCGCCGACATGTACGGCGTCGACAAGGTCGACACCGAGCGGTTGC
CGCTCGTACAGATGCCGACGACGGCAGGCACCGGTTCGGAGGTGACGGCCGTGTCGATCGTCACGGTGGGCGAGGCGCGC
AAGATGGGCGTCGTGTCGCCGCATCTGTTCGCCGACGTCGCGATTCTCGACGCCGAGCTGACGCTCGGGCTGCCGCGCGC
GGCGACGGCCGCGACCGGCATCGACGCGATGGTGCATGCGATCGAGGCCTACACGTCCGCGCGGCTGAAGAATCCGGTGT
CCGACATGCTGGCCGTGCAGGCGCTGACGCTGCTGTCGCGCAACCTGCTCGCCGCATGCGACGACGGCCACGACCGGCAC
GCGCGGGAAGCGATGCTGGTCGGCGCGATGTTCGCAGGTCAGGCGTTCGCGAACGCGCCGGTCGCGGCCGTGCATGCGCT
CGCGTATCCGGTCGGCGGTATTTTCCACGTGCCGCACGGGCTGTCGAACGCGCTCGTGCTGCCGCATGTGCTGCGCTTCA
ACGCGGAAGCGGCCGCGTCGCAGTATGCGGAACTCGCGGCGATCGTCACGCCGTCGGCGACGGGTAGCGACGAGGCGAAG
ACGCACGCACTGATCGACGAGATCGACCGGCTGATCGTCGCGACCGGCATTCCGCGTACGCTGCGCGAGGTCGGCATCGG
CGAAGGCGATCTGCCGCGGATGGCCGCGGACGCGATGCTGCAGACGCGCCTGCTCGTCAACAATCCGCGCGAAGTGACGG
AGGCCGACGCGCTCGAGATCTATCGGCGCGCGTGGTGA

Upstream 100 bases:

>100_bases
TCGGTGTCGGGGCGATCATTCCGTTGCTCGATCGCCGCGACGTGACGCGCTTCATGGTGCAGCCCGACACCGGCACGGCG
ACGCTACCGGGAGAAACCCG

Downstream 100 bases:

>100_bases
GCGGGTCGCGCGGCGACGCACGCGCAGCCCAGCGCGAGCGCGACCAGCGCGCAGCCGGCCCACGGCGCGAGCAGCAGCGC
GCCGCGCTCGACGAGTACGC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: Alcohol dehydrogenase II; ADH II [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MNPFQFRTVPTLIVEYGAARRLGALLRARFPTLARLCVVTDAFLHRSGVLAPALDSLAAHGWQVTVIDDVIADPPERVVL
DATARAVAADAQIVLGLGGGSSMDVAKLIAVLAPGRQPLADMYGVDKVDTERLPLVQMPTTAGTGSEVTAVSIVTVGEAR
KMGVVSPHLFADVAILDAELTLGLPRAATAATGIDAMVHAIEAYTSARLKNPVSDMLAVQALTLLSRNLLAACDDGHDRH
AREAMLVGAMFAGQAFANAPVAAVHALAYPVGGIFHVPHGLSNALVLPHVLRFNAEAAASQYAELAAIVTPSATGSDEAK
THALIDEIDRLIVATGIPRTLREVGIGEGDLPRMAADAMLQTRLLVNNPREVTEADALEIYRRAW

Sequences:

>Translated_385_residues
MNPFQFRTVPTLIVEYGAARRLGALLRARFPTLARLCVVTDAFLHRSGVLAPALDSLAAHGWQVTVIDDVIADPPERVVL
DATARAVAADAQIVLGLGGGSSMDVAKLIAVLAPGRQPLADMYGVDKVDTERLPLVQMPTTAGTGSEVTAVSIVTVGEAR
KMGVVSPHLFADVAILDAELTLGLPRAATAATGIDAMVHAIEAYTSARLKNPVSDMLAVQALTLLSRNLLAACDDGHDRH
AREAMLVGAMFAGQAFANAPVAAVHALAYPVGGIFHVPHGLSNALVLPHVLRFNAEAAASQYAELAAIVTPSATGSDEAK
THALIDEIDRLIVATGIPRTLREVGIGEGDLPRMAADAMLQTRLLVNNPREVTEADALEIYRRAW
>Mature_385_residues
MNPFQFRTVPTLIVEYGAARRLGALLRARFPTLARLCVVTDAFLHRSGVLAPALDSLAAHGWQVTVIDDVIADPPERVVL
DATARAVAADAQIVLGLGGGSSMDVAKLIAVLAPGRQPLADMYGVDKVDTERLPLVQMPTTAGTGSEVTAVSIVTVGEAR
KMGVVSPHLFADVAILDAELTLGLPRAATAATGIDAMVHAIEAYTSARLKNPVSDMLAVQALTLLSRNLLAACDDGHDRH
AREAMLVGAMFAGQAFANAPVAAVHALAYPVGGIFHVPHGLSNALVLPHVLRFNAEAAASQYAELAAIVTPSATGSDEAK
THALIDEIDRLIVATGIPRTLREVGIGEGDLPRMAADAMLQTRLLVNNPREVTEADALEIYRRAW

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=406, Percent_Identity=28.0788177339901, Blast_Score=120, Evalue=3e-27,
Organism=Escherichia coli, GI48994951, Length=356, Percent_Identity=35.9550561797753, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI1789163, Length=355, Percent_Identity=33.8028169014084, Blast_Score=194, Evalue=6e-51,
Organism=Escherichia coli, GI87082107, Length=378, Percent_Identity=35.1851851851852, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1787493, Length=369, Percent_Identity=33.8753387533875, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI1789386, Length=365, Percent_Identity=25.7534246575342, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17537053, Length=362, Percent_Identity=27.0718232044199, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6321181, Length=299, Percent_Identity=37.4581939799331, Blast_Score=189, Evalue=9e-49,
Organism=Drosophila melanogaster, GI24657991, Length=418, Percent_Identity=28.2296650717703, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 40518; Mature: 40518

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00913 ADH_IRON_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPFQFRTVPTLIVEYGAARRLGALLRARFPTLARLCVVTDAFLHRSGVLAPALDSLAAH
CCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
GWQVTVIDDVIADPPERVVLDATARAVAADAQIVLGLGGGSSMDVAKLIAVLAPGRQPLA
CEEEEEEHHHHCCCCCCEEEEHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCCCHH
DMYGVDKVDTERLPLVQMPTTAGTGSEVTAVSIVTVGEARKMGVVSPHLFADVAILDAEL
HHCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHEEEHHH
TLGLPRAATAATGIDAMVHAIEAYTSARLKNPVSDMLAVQALTLLSRNLLAACDDGHDRH
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AREAMLVGAMFAGQAFANAPVAAVHALAYPVGGIFHVPHGLSNALVLPHVLRFNAEAAAS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHCCCHHHHH
QYAELAAIVTPSATGSDEAKTHALIDEIDRLIVATGIPRTLREVGIGEGDLPRMAADAML
HHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHH
QTRLLVNNPREVTEADALEIYRRAW
HHHHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNPFQFRTVPTLIVEYGAARRLGALLRARFPTLARLCVVTDAFLHRSGVLAPALDSLAAH
CCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
GWQVTVIDDVIADPPERVVLDATARAVAADAQIVLGLGGGSSMDVAKLIAVLAPGRQPLA
CEEEEEEHHHHCCCCCCEEEEHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCCCHH
DMYGVDKVDTERLPLVQMPTTAGTGSEVTAVSIVTVGEARKMGVVSPHLFADVAILDAEL
HHCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHEEEHHH
TLGLPRAATAATGIDAMVHAIEAYTSARLKNPVSDMLAVQALTLLSRNLLAACDDGHDRH
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AREAMLVGAMFAGQAFANAPVAAVHALAYPVGGIFHVPHGLSNALVLPHVLRFNAEAAAS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHCCCHHHHH
QYAELAAIVTPSATGSDEAKTHALIDEIDRLIVATGIPRTLREVGIGEGDLPRMAADAML
HHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHH
QTRLLVNNPREVTEADALEIYRRAW
HHHHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3584063; 2308827; 2935393 [H]