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The map label for this gene is gntR [H]

Identifier: 189352694

GI number: 189352694

Start: 792986

End: 793993

Strand: Direct

Name: gntR [H]

Synonym: BMULJ_03926

Alternate gene names: 189352694

Gene position: 792986-793993 (Clockwise)

Preceding gene: 189352692

Following gene: 189352695

Centisome position: 32.06

GC content: 69.64

Gene sequence:

>1008_bases
ATGTCCGACGTCGCGCGCCTGGCCGGCGTGTCGAAGATGACCGTCTCGCGCGTGCTTGCCGACCGCAGCGTGTCGGCGGC
AACGCGCGAGCGCGTGCAGCGCGCGATCGAGCAGCTCGGCTATGTCGCCGATGCGGCGGCCGGCGCACTGTCGTCCGGAC
GTTCGGAGTTCGTCGCGGTGCTGGTGCCGTCGCTGTCGAGCTCGAACTTCTCGGATACGGTGCAGGGTCTGACCGAGGCG
CTCGAACCGCACGGCCTGCAGCTGCTGATCGGCGACACCGATTATTCGCTCGAGCGCGAGGAACGTCTGGTGCGCCAGCT
GCTGCGCTATCAGCCGCGTGCGATCGCGCTGACGGGCGCGCAGCATACCGACGCGACGCGGCAACTGCTCGAGCGCACGG
ACGTGCCGATCGTCGAGATGTGGGACTGGCCGGCCGATCCGGTCGATCGCGTCGTCGGCTTCTCGAACGCGAAGGCCGCG
CGCGAAATGGTGCGCTATCTCGCGGGCAAAGGGCATCGGCGTATCGGCTTTCTCGCGGGCGCCGGCGATCTCGACCGGCG
CGGCCTCGAGCGACTGCGCGGCTATCAGCAGGAGATGAAGGCGCTCGGCCTCGCTCCGCGCGTCGTGCGGCTCGGCGATG
CGCCCGTGACGATGAGTCACGGCGGCCCCGCGATGGCCGCGCTGCTCGCGCAATGGCCGGACACGCAGGCAGTGATGTGC
GTCAGCGACATGTCGGCATTCGGCGCGATCATGGAGTGTCATCGGCGCGGGCTCGCGGTGCCGGACGACATCGCGATCGC
CGGCTTCGGCAATTTCGAGGTCGCATCGTGCTGCCATCCCACGATCACGACGATGTCCGTCGACGCACTCGGCATCGGGC
GCCGTACCGGCGAGATGCTGCTCGCGGCGCTCGACGCGGCCGACGCCGACGCCGACGCCGCGGAATCGGCGCGCGTCGCA
AAGAAGGTGCGGATCGAATACGGCATCGTCGAGCGCGACAGCGCGTAG

Upstream 100 bases:

>100_bases
CGGCGGGCCGTCGCTTGCGGCTATCATACGGTCGTTTCAACCCCGCTCCAGATCGTCGATGGCCAAATCCGCCGCCGCTA
CCAAGACCACACCGCCCCGC

Downstream 100 bases:

>100_bases
CGCGGCGCGACGATCGCGTCGCGCGGCGGCGCCTGCTTTCCTGTTGTCGATGCCTGGTGCGACGCGCCGGCGCGTGCTAG
TATCGGCGCTGATGTTACCG

Product: LacI family gluconate utilization system Gnt-I transcriptional repressor

Products: NA

Alternate protein names: L-idonate regulatory protein [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSDVARLAGVSKMTVSRVLADRSVSAATRERVQRAIEQLGYVADAAAGALSSGRSEFVAVLVPSLSSSNFSDTVQGLTEA
LEPHGLQLLIGDTDYSLEREERLVRQLLRYQPRAIALTGAQHTDATRQLLERTDVPIVEMWDWPADPVDRVVGFSNAKAA
REMVRYLAGKGHRRIGFLAGAGDLDRRGLERLRGYQQEMKALGLAPRVVRLGDAPVTMSHGGPAMAALLAQWPDTQAVMC
VSDMSAFGAIMECHRRGLAVPDDIAIAGFGNFEVASCCHPTITTMSVDALGIGRRTGEMLLAALDAADADADAAESARVA
KKVRIEYGIVERDSA

Sequences:

>Translated_335_residues
MSDVARLAGVSKMTVSRVLADRSVSAATRERVQRAIEQLGYVADAAAGALSSGRSEFVAVLVPSLSSSNFSDTVQGLTEA
LEPHGLQLLIGDTDYSLEREERLVRQLLRYQPRAIALTGAQHTDATRQLLERTDVPIVEMWDWPADPVDRVVGFSNAKAA
REMVRYLAGKGHRRIGFLAGAGDLDRRGLERLRGYQQEMKALGLAPRVVRLGDAPVTMSHGGPAMAALLAQWPDTQAVMC
VSDMSAFGAIMECHRRGLAVPDDIAIAGFGNFEVASCCHPTITTMSVDALGIGRRTGEMLLAALDAADADADAAESARVA
KKVRIEYGIVERDSA
>Mature_334_residues
SDVARLAGVSKMTVSRVLADRSVSAATRERVQRAIEQLGYVADAAAGALSSGRSEFVAVLVPSLSSSNFSDTVQGLTEAL
EPHGLQLLIGDTDYSLEREERLVRQLLRYQPRAIALTGAQHTDATRQLLERTDVPIVEMWDWPADPVDRVVGFSNAKAAR
EMVRYLAGKGHRRIGFLAGAGDLDRRGLERLRGYQQEMKALGLAPRVVRLGDAPVTMSHGGPAMAALLAQWPDTQAVMCV
SDMSAFGAIMECHRRGLAVPDDIAIAGFGNFEVASCCHPTITTMSVDALGIGRRTGEMLLAALDAADADADAAESARVAK
KVRIEYGIVERDSA

Specific function: Idn operon regulator. May repress gntKU and gntT genes when growing on L-idonate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790715, Length=317, Percent_Identity=32.4921135646688, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI48994940, Length=303, Percent_Identity=33.6633663366337, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1790369, Length=306, Percent_Identity=33.0065359477124, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1790194, Length=290, Percent_Identity=32.0689655172414, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788474, Length=302, Percent_Identity=30.1324503311258, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789202, Length=288, Percent_Identity=30.5555555555556, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1789068, Length=326, Percent_Identity=26.3803680981595, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1787948, Length=308, Percent_Identity=28.2467532467532, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1787906, Length=253, Percent_Identity=32.0158102766798, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1787580, Length=319, Percent_Identity=24.7648902821317, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1786540, Length=304, Percent_Identity=28.6184210526316, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790689, Length=303, Percent_Identity=27.3927392739274, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786268, Length=328, Percent_Identity=25.609756097561, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35974; Mature: 35843

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVARLAGVSKMTVSRVLADRSVSAATRERVQRAIEQLGYVADAAAGALSSGRSEFVAV
CCCHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEE
LVPSLSSSNFSDTVQGLTEALEPHGLQLLIGDTDYSLEREERLVRQLLRYQPRAIALTGA
EECCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEECC
QHTDATRQLLERTDVPIVEMWDWPADPVDRVVGFSNAKAAREMVRYLAGKGHRRIGFLAG
CCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEEC
AGDLDRRGLERLRGYQQEMKALGLAPRVVRLGDAPVTMSHGGPAMAALLAQWPDTQAVMC
CCCHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCEEECCCCHHHHHHHHHCCCCCEEEE
VSDMSAFGAIMECHRRGLAVPDDIAIAGFGNFEVASCCHPTITTMSVDALGIGRRTGEML
HHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHCCCCHHEEEEHHHCCCCHHHHHH
LAALDAADADADAAESARVAKKVRIEYGIVERDSA
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCEECCCC
>Mature Secondary Structure 
SDVARLAGVSKMTVSRVLADRSVSAATRERVQRAIEQLGYVADAAAGALSSGRSEFVAV
CCHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEE
LVPSLSSSNFSDTVQGLTEALEPHGLQLLIGDTDYSLEREERLVRQLLRYQPRAIALTGA
EECCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEECC
QHTDATRQLLERTDVPIVEMWDWPADPVDRVVGFSNAKAAREMVRYLAGKGHRRIGFLAG
CCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEEC
AGDLDRRGLERLRGYQQEMKALGLAPRVVRLGDAPVTMSHGGPAMAALLAQWPDTQAVMC
CCCHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCEEECCCCHHHHHHHHHCCCCCEEEE
VSDMSAFGAIMECHRRGLAVPDDIAIAGFGNFEVASCCHPTITTMSVDALGIGRRTGEML
HHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHCCCCHHEEEEHHHCCCCHHHHHH
LAALDAADADADAAESARVAKKVRIEYGIVERDSA
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 9658018 [H]