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The map label for this gene is frlR [H]

Identifier: 189352632

GI number: 189352632

Start: 720685

End: 721500

Strand: Direct

Name: frlR [H]

Synonym: BMULJ_03863

Alternate gene names: 189352632

Gene position: 720685-721500 (Clockwise)

Preceding gene: 189352626

Following gene: 189352633

Centisome position: 29.14

GC content: 67.4

Gene sequence:

>816_bases
ATGACATCGAACCAGGCGAATACCGCGAATCCCACCGGCGCAGGCAGCCCAGGGCAGCCGGGCGCGAGCGATTCCGCGCC
TGCATCCGCGGCCGCGCAGTCGCCGACGTTCAGCCCGTTATACCAGCAGATCAAGGCATTGATCACGCAGAGCCTCGAAA
GCGGCGAATGGAAGCCGGGCGAGATCATTCCGAGCGAAGTCGAACTCGCGGCGCGCTACAAGGTCAGCCAGGGCACCGTG
CGCAAGGCGATCGACGAGCTGGCCGCGGAAAACCTCGTGGTCAGGCGGCAGGGCAAGGGTACGTTTGTTGCAACGCACAA
TGAGGAGCGCGCGCAGTTCCGTTTCCTGCGGCTGCTCGCGGACGACGGCGCCGAGCACGCGCACGTGAGCCGGCTGCTCG
AATGCCGGCGCCTGCGCGCGCCGGCCGAGATCGCGCGCCAGCTCGAGCTGAAGCCGGCCGATCCGGTCGTGCAGGTGCGG
CGCCTGCTCGAGTTCGAGGGCGAGGCGACGGTGCTCGACGAGATCTGGCTGCCGGGCGCGATGTTCCGCGGCCTCACGTT
CGAGCGGCTCAGCGAGTACAAGGGGCCGCTCTACGCGATGTTCGAAACGGAGTTCGGCACGCGCATGATCCGGGCGTCGG
AGAAGATCCGCGCGGTGGCGGCGGAGCCGACGGTGGCCGACCTGCTGCACGTGCCTGCGGGCTTTCCGCTGCTGTCGGTC
GAGCGTGTGTCCTATACCTATGGCGATCGGCCCGTCGAAGTGCGGCGCGGCTGGTATGTCACGACCGGGTACTACTATCA
GAACGACTTGAGCTGA

Upstream 100 bases:

>100_bases
GCAGGCGCAAAGTCAAACGGTATCATATGTCTTATATAAGACAGATGTTTTGCGCAATTTGAGTGGACGGAAAACTGCGG
TTTGTGATGAAATGCGCGCC

Downstream 100 bases:

>100_bases
CGACGTATCGGCGCAAGCGCCGTGCATTCGCGTTCGACACGTTCGCGAAGCACGTTTCGGGCCGCCTTTGTTCTCGTTCG
CGTAACGATCCAGAGCAGAC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MTSNQANTANPTGAGSPGQPGASDSAPASAAAQSPTFSPLYQQIKALITQSLESGEWKPGEIIPSEVELAARYKVSQGTV
RKAIDELAAENLVVRRQGKGTFVATHNEERAQFRFLRLLADDGAEHAHVSRLLECRRLRAPAEIARQLELKPADPVVQVR
RLLEFEGEATVLDEIWLPGAMFRGLTFERLSEYKGPLYAMFETEFGTRMIRASEKIRAVAAEPTVADLLHVPAGFPLLSV
ERVSYTYGDRPVEVRRGWYVTTGYYYQNDLS

Sequences:

>Translated_271_residues
MTSNQANTANPTGAGSPGQPGASDSAPASAAAQSPTFSPLYQQIKALITQSLESGEWKPGEIIPSEVELAARYKVSQGTV
RKAIDELAAENLVVRRQGKGTFVATHNEERAQFRFLRLLADDGAEHAHVSRLLECRRLRAPAEIARQLELKPADPVVQVR
RLLEFEGEATVLDEIWLPGAMFRGLTFERLSEYKGPLYAMFETEFGTRMIRASEKIRAVAAEPTVADLLHVPAGFPLLSV
ERVSYTYGDRPVEVRRGWYVTTGYYYQNDLS
>Mature_270_residues
TSNQANTANPTGAGSPGQPGASDSAPASAAAQSPTFSPLYQQIKALITQSLESGEWKPGEIIPSEVELAARYKVSQGTVR
KAIDELAAENLVVRRQGKGTFVATHNEERAQFRFLRLLADDGAEHAHVSRLLECRRLRAPAEIARQLELKPADPVVQVRR
LLEFEGEATVLDEIWLPGAMFRGLTFERLSEYKGPLYAMFETEFGTRMIRASEKIRAVAAEPTVADLLHVPAGFPLLSVE
RVSYTYGDRPVEVRRGWYVTTGYYYQNDLS

Specific function: May regulate the transcription of the frlABCD operon [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082252, Length=217, Percent_Identity=28.110599078341, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786950, Length=235, Percent_Identity=29.3617021276596, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1790118, Length=210, Percent_Identity=29.0476190476191, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790540, Length=219, Percent_Identity=30.1369863013699, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788418, Length=221, Percent_Identity=24.8868778280543, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 29983; Mature: 29852

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSNQANTANPTGAGSPGQPGASDSAPASAAAQSPTFSPLYQQIKALITQSLESGEWKPG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
EIIPSEVELAARYKVSQGTVRKAIDELAAENLVVRRQGKGTFVATHNEERAQFRFLRLLA
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCEEEEECCCCCEEEECCCHHHHHHHHHHHH
DDGAEHAHVSRLLECRRLRAPAEIARQLELKPADPVVQVRRLLEFEGEATVLDEIWLPGA
CCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEHHHHHCCHH
MFRGLTFERLSEYKGPLYAMFETEFGTRMIRASEKIRAVAAEPTVADLLHVPAGFPLLSV
HHHCCCHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEH
ERVSYTYGDRPVEVRRGWYVTTGYYYQNDLS
HHEEHCCCCCCEEEECCEEEEECEEECCCCC
>Mature Secondary Structure 
TSNQANTANPTGAGSPGQPGASDSAPASAAAQSPTFSPLYQQIKALITQSLESGEWKPG
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
EIIPSEVELAARYKVSQGTVRKAIDELAAENLVVRRQGKGTFVATHNEERAQFRFLRLLA
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCEEEEECCCCCEEEECCCHHHHHHHHHHHH
DDGAEHAHVSRLLECRRLRAPAEIARQLELKPADPVVQVRRLLEFEGEATVLDEIWLPGA
CCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEHHHHHCCHH
MFRGLTFERLSEYKGPLYAMFETEFGTRMIRASEKIRAVAAEPTVADLLHVPAGFPLLSV
HHHCCCHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEH
ERVSYTYGDRPVEVRRGWYVTTGYYYQNDLS
HHEEHCCCCCCEEEECCEEEEECEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]