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The map label for this gene is yebQ [H]

Identifier: 189352622

GI number: 189352622

Start: 708131

End: 709480

Strand: Direct

Name: yebQ [H]

Synonym: BMULJ_03853

Alternate gene names: 189352622

Gene position: 708131-709480 (Clockwise)

Preceding gene: 189352621

Following gene: 189352624

Centisome position: 28.63

GC content: 71.11

Gene sequence:

>1350_bases
ATGGCCGCCGTGCTGCTCGCCGTCGCGCTCGCGACGCTCGATACGGCGATCGCCAACACCGCATTGCCCGCGATCGCGAC
CGACCTGCATGCGTCGCCGGCCGCATCGGTGTGGATCATCAACGCGTATCAGCTCGCGATGGTCGCGACGTTGCTGCCGT
TCGCGTCGCTCGGCGACATCGTCGGGCACAAGCGCGTGTACGTCGGCGGTCTCGCCGTGTTTACACTCGCGTCGCTCGGC
TGTGCGCTCGCGTCGACGCTGCCGCAGCTCACCGCGGCGCGCATCGTGCAGGGCTTGGGCGCGAGCGCGATCATGAGCGT
CAACATCGCGCTGATCCGCAACCTGTTTCCCGCGCATCGGCTCGGGCGCGGCGTCGGCTTCAATGCGCTCGTCGTCGGCG
TGTCGTTCGCGGTCGGGCCGACGATCGCATCGCTGATACTGTCCGCCGCCGCATGGCCGTGGCTGTTCGCGGTCAACGTG
CCGCTCGGCGTGCTCGCGCTCGCCGTTGCGATTCCGTCGCTGCCGGAAGCCGTGCGCGGCAAGCATGCCTTCGATCCGCT
CGCCGCGCTGTTCAACGTGATCGCGTTCTCGGCGCTGATCTTTGCGCTCGGCGAATTCGCGCAGCGCGGCCCGCTGCGCG
TCGTGCTCGTAGCCGCCGCCGTCGCGCTCGCATTCGGCGCGCTGCTGATCCGCCGGGAGGCCGGCCACCCGGCGCCGATG
CTGCCGGTCGACCTGTTTCGCCGGCCCGTGTTCGCGCTGTCCGCGGTGACCGCCGTCTGCGCGTTCGCGGCGCAAGGGCT
CGCGTTCGTGTCGTTGCCGTTCTACTTCGAGACGGTCCTGCACCGCAGCGCGGTCGACACCGGTTTTCTGATGACGCCGT
GGTCGGCCGTCGTCGCGCTCGCCGCACCGATCGCCGGACGACTGTCCGATCGCTATCCGCCGGGACTGCTCGGTGCAATC
GGACTCGCGTTGCTCGGCGCCGGGATGGCGTCGCTTGCCGCGTTGCCGGCCGCACCGAGCGCGATCGACATCGGCTGGCG
GATGATGCTGTGCGGCGCCGGCTTCGGCTTTTTCCAGTCGCCGAACCTGAAGGCGCTGATGTCGAGCGCGCCGCCGGAAC
GCAGCGGCGGTGCGAGCGGCATCATCGGCACCGCGCGGCTGATCGGGCAGGCGACGGGCGCCGCGCTCGTCGCGCTGTCG
TTCGGCATTGCCGGGCATCACGGGCCGACGCTCGCGCTGGTGCTCGGTGCCGCGTTCGCCTGCGCCGCGAGCGTGGCGAG
CGGACTGCGGCTGTTTGCGCGCTCGCATCGCGCGGGCGTCGCCGTCGCGTCGGAGCGCGCGTCGAAGTAG

Upstream 100 bases:

>100_bases
TTCAATCCGCGACGCCCTGCGTCGCCCGTCTGCCGAACCGATCGTGTCCGAACTCGCTTCTCCTGCCGGTGCCGCCGAAC
CGGCCGTCAACTGGCGCGCG

Downstream 100 bases:

>100_bases
CCGCAATGTCGTGCGGCGCGCACGTGCGCGCCGCGTCCCGTGCCTGTGCGTCGCTCAGAAGCCGCCCGACTGGATCAGCT
TGTTGAGGTTCGCGATGTTC

Product: multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MAAVLLAVALATLDTAIANTALPAIATDLHASPAASVWIINAYQLAMVATLLPFASLGDIVGHKRVYVGGLAVFTLASLG
CALASTLPQLTAARIVQGLGASAIMSVNIALIRNLFPAHRLGRGVGFNALVVGVSFAVGPTIASLILSAAAWPWLFAVNV
PLGVLALAVAIPSLPEAVRGKHAFDPLAALFNVIAFSALIFALGEFAQRGPLRVVLVAAAVALAFGALLIRREAGHPAPM
LPVDLFRRPVFALSAVTAVCAFAAQGLAFVSLPFYFETVLHRSAVDTGFLMTPWSAVVALAAPIAGRLSDRYPPGLLGAI
GLALLGAGMASLAALPAAPSAIDIGWRMMLCGAGFGFFQSPNLKALMSSAPPERSGGASGIIGTARLIGQATGAALVALS
FGIAGHHGPTLALVLGAAFACAASVASGLRLFARSHRAGVAVASERASK

Sequences:

>Translated_449_residues
MAAVLLAVALATLDTAIANTALPAIATDLHASPAASVWIINAYQLAMVATLLPFASLGDIVGHKRVYVGGLAVFTLASLG
CALASTLPQLTAARIVQGLGASAIMSVNIALIRNLFPAHRLGRGVGFNALVVGVSFAVGPTIASLILSAAAWPWLFAVNV
PLGVLALAVAIPSLPEAVRGKHAFDPLAALFNVIAFSALIFALGEFAQRGPLRVVLVAAAVALAFGALLIRREAGHPAPM
LPVDLFRRPVFALSAVTAVCAFAAQGLAFVSLPFYFETVLHRSAVDTGFLMTPWSAVVALAAPIAGRLSDRYPPGLLGAI
GLALLGAGMASLAALPAAPSAIDIGWRMMLCGAGFGFFQSPNLKALMSSAPPERSGGASGIIGTARLIGQATGAALVALS
FGIAGHHGPTLALVLGAAFACAASVASGLRLFARSHRAGVAVASERASK
>Mature_448_residues
AAVLLAVALATLDTAIANTALPAIATDLHASPAASVWIINAYQLAMVATLLPFASLGDIVGHKRVYVGGLAVFTLASLGC
ALASTLPQLTAARIVQGLGASAIMSVNIALIRNLFPAHRLGRGVGFNALVVGVSFAVGPTIASLILSAAAWPWLFAVNVP
LGVLALAVAIPSLPEAVRGKHAFDPLAALFNVIAFSALIFALGEFAQRGPLRVVLVAAAVALAFGALLIRREAGHPAPML
PVDLFRRPVFALSAVTAVCAFAAQGLAFVSLPFYFETVLHRSAVDTGFLMTPWSAVVALAAPIAGRLSDRYPPGLLGAIG
LALLGAGMASLAALPAAPSAIDIGWRMMLCGAGFGFFQSPNLKALMSSAPPERSGGASGIIGTARLIGQATGAALVALSF
GIAGHHGPTLALVLGAAFACAASVASGLRLFARSHRAGVAVASERASK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=438, Percent_Identity=52.0547945205479, Blast_Score=427, Evalue=1e-121,
Organism=Escherichia coli, GI1790195, Length=293, Percent_Identity=30.3754266211604, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789042, Length=404, Percent_Identity=24.2574257425743, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788392, Length=287, Percent_Identity=28.2229965156794, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788710, Length=333, Percent_Identity=23.4234234234234, Blast_Score=85, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6323735, Length=310, Percent_Identity=24.5161290322581, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45417; Mature: 45286

Theoretical pI: Translated: 11.07; Mature: 11.07

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAVLLAVALATLDTAIANTALPAIATDLHASPAASVWIINAYQLAMVATLLPFASLGDI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
VGHKRVYVGGLAVFTLASLGCALASTLPQLTAARIVQGLGASAIMSVNIALIRNLFPAHR
HCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LGRGVGFNALVVGVSFAVGPTIASLILSAAAWPWLFAVNVPLGVLALAVAIPSLPEAVRG
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEECCCHHHHHHHHHHCCCCHHHCC
KHAFDPLAALFNVIAFSALIFALGEFAQRGPLRVVLVAAAVALAFGALLIRREAGHPAPM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LPVDLFRRPVFALSAVTAVCAFAAQGLAFVSLPFYFETVLHRSAVDTGFLMTPWSAVVAL
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHH
AAPIAGRLSDRYPPGLLGAIGLALLGAGMASLAALPAAPSAIDIGWRMMLCGAGFGFFQS
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCC
PNLKALMSSAPPERSGGASGIIGTARLIGQATGAALVALSFGIAGHHGPTLALVLGAAFA
CCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
CAASVASGLRLFARSHRAGVAVASERASK
HHHHHHHHHHHHHHHCCCCCEEHHHCCCC
>Mature Secondary Structure 
AAVLLAVALATLDTAIANTALPAIATDLHASPAASVWIINAYQLAMVATLLPFASLGDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH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HHHHHHHHHHHHHHHCCCCCEEHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]