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The map label for this gene is potC [H]

Identifier: 189352621

GI number: 189352621

Start: 706891

End: 707727

Strand: Direct

Name: potC [H]

Synonym: BMULJ_03852

Alternate gene names: 189352621

Gene position: 706891-707727 (Clockwise)

Preceding gene: 189352620

Following gene: 189352622

Centisome position: 28.58

GC content: 67.14

Gene sequence:

>837_bases
ATGAAACTTGCCAGGCCGCTGTTTGCGCCGCACATGTCGTTCGTCGAGCGCGCGTGGTACGTCGCGTTGCGCGTGCTCGT
CGTGCTCACGCTGCTGTATCTGATCCTGCCGGTGCTTGCGATCGTGCCGCTGTCGTTCTCGTCGAGCACGTTCCTCGTGT
ATCCGATTCCCGGCTTCTCGACGCGCTGGTACGAAAACCTGATCGCGTCGGACGAGTGGCGCATGGCCGCGAAGAACAGC
TTCATCGTGGCGCCCTCGGCGACGCTCGTGGCGACCGTGCTCGGCACGCTGGCCGCGATCGGGCTGACGAAGGCCGAGTT
CCGCGGCAAAGGGCTGCTGATGGCGGTGCTGCTCTCGCCGATGATCGTGCCGGTGGTGGTGGTCGGTGTCGGCATGTATC
TGTTCTTCGCGCCGCTGGGGCTCGCGAACACGTACACGGGGCTGATCGCGGCGCACGCGGCGCTCGGCGTGCCGTTCGTC
GTGACGACGGTGGCCGCGACGCTGCAGGGCTTCAACCAGAACCTCGTGCGCGCGAGCCTGTCGCTGGGCGCGAATCCCGT
GACGACGTTCTTCCGCGTGACGCTGCCGGTGATCGCGCCGGGCGTGATGTCGGGTGCGCTGTTCGCGTTCGCGACGTCGT
TCGACGAAGTGGTCGTCACGCTGTTTCTGGCCGGTGCGGACCAGACGACGCTGCCGCGGCAGATGTTTACCGGCATCCGC
GAAAACATCAGCCCGACGATCGCGGCGCTCGCGACGATCCTGATCGTGTTCTCGACGAGCCTGCTGCTCGCGCTCGAGTG
GCTGCGCGGGCGTCAGGCGCGGCGCGCGGTGGCGTAA

Upstream 100 bases:

>100_bases
CTCGCGGCGACGCTCGTGCTGTACGCGGTGTACGGGCGCTTCACGCGCACCAACGTGAGCCTCGGCTGAGCGCGGGCCGA
CAGGGAAGGAGAACGGAACC

Downstream 100 bases:

>100_bases
GGCGCAAGACTCGCGAGACGCGGAAGACTGGGACGACACGCGAGACGCGAGAGACCAGACCGGCCGCGAAGCCTGCGCGG
CGCGAACGCGCGCACCGTGC

Product: spermidine/putrescine transport system permease protein

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MKLARPLFAPHMSFVERAWYVALRVLVVLTLLYLILPVLAIVPLSFSSSTFLVYPIPGFSTRWYENLIASDEWRMAAKNS
FIVAPSATLVATVLGTLAAIGLTKAEFRGKGLLMAVLLSPMIVPVVVVGVGMYLFFAPLGLANTYTGLIAAHAALGVPFV
VTTVAATLQGFNQNLVRASLSLGANPVTTFFRVTLPVIAPGVMSGALFAFATSFDEVVVTLFLAGADQTTLPRQMFTGIR
ENISPTIAALATILIVFSTSLLLALEWLRGRQARRAVA

Sequences:

>Translated_278_residues
MKLARPLFAPHMSFVERAWYVALRVLVVLTLLYLILPVLAIVPLSFSSSTFLVYPIPGFSTRWYENLIASDEWRMAAKNS
FIVAPSATLVATVLGTLAAIGLTKAEFRGKGLLMAVLLSPMIVPVVVVGVGMYLFFAPLGLANTYTGLIAAHAALGVPFV
VTTVAATLQGFNQNLVRASLSLGANPVTTFFRVTLPVIAPGVMSGALFAFATSFDEVVVTLFLAGADQTTLPRQMFTGIR
ENISPTIAALATILIVFSTSLLLALEWLRGRQARRAVA
>Mature_278_residues
MKLARPLFAPHMSFVERAWYVALRVLVVLTLLYLILPVLAIVPLSFSSSTFLVYPIPGFSTRWYENLIASDEWRMAAKNS
FIVAPSATLVATVLGTLAAIGLTKAEFRGKGLLMAVLLSPMIVPVVVVGVGMYLFFAPLGLANTYTGLIAAHAALGVPFV
VTTVAATLQGFNQNLVRASLSLGANPVTTFFRVTLPVIAPGVMSGALFAFATSFDEVVVTLFLAGADQTTLPRQMFTGIR
ENISPTIAALATILIVFSTSLLLALEWLRGRQARRAVA

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=222, Percent_Identity=33.7837837837838, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1787081, Length=242, Percent_Identity=33.0578512396694, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787714, Length=240, Percent_Identity=32.5, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1788764, Length=230, Percent_Identity=30, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787080, Length=131, Percent_Identity=29.0076335877863, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29790; Mature: 29790

Theoretical pI: Translated: 10.75; Mature: 10.75

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]