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The map label for this gene is luxQ [H]

Identifier: 189352590

GI number: 189352590

Start: 669021

End: 670601

Strand: Direct

Name: luxQ [H]

Synonym: BMULJ_03821

Alternate gene names: 189352590

Gene position: 669021-670601 (Clockwise)

Preceding gene: 189352588

Following gene: 189352595

Centisome position: 27.05

GC content: 65.65

Gene sequence:

>1581_bases
ATGACGACCTACCTATTGCCGCATCCGGTGGAATCCGCCGAGCAAGCGCGCGACAGACTCGAGCGCGCCGTCGACGCCGC
CGAACTCGGCACCTTCCATTGCCCGTTGCCGCTCGACCGGCTGTTCTGGAATGCGCGCTGCAAGGCGCACTTCTGGCTGG
ACCCCGATACGCCTGACGACGAAATCAATATCGACACCTTCTACCGGATCCTGCACGCGGACGATCGCGCAAGCGTGCGC
GCCGCCGTCGACGCCGCCGTGACACACGGCGGCTTGTTCGACGTCGAGTATCGAACGGTCTCCGCACGTGGCGACGTTCG
CTGGCTCAGGGCCAAGGGAAGTGCACATGTCGGCACCGATGGGCGTCCGGTGCGGCTCGACGGTATTACGATCGACATTT
CGGCGCAAAAGCGGCTGGAGCGCGAGCGCGACGCGCTGATCGAGAGCGAACGTATCCAGCGATTCGCCGCACAAAGCGCA
AGCGAGTCGAAGGACGCCTTCATTGCCGCGGTGTCCCATGAGCTCAGAGCGCCGTCGACGGCCATTCTCGGCTGGGCCGA
CATGCTCGGCGACGCAGCCGACGACGCGGCGGTCGTGCGAGAGGGTGTCGCCGTCATCCGCCGAAATATCCTCGCGCTGA
CGCGGTTGGTCGACGACCTGCTCGACGCGAGCCGCCTGGGGCAGGGCAAGTTCGCGATCGAGTCGGCGCCCGTGTCGATC
GCCGAATGCCTGAACGCCGCCTTACAGGACGTCGCGCCTATTGCCGAAACGAAAGGCGTGCGGATTGCCGAGCCGGGTGC
GGACGACGGCCTCGTGTCGGGCGACGCAGCGAGGCTCGAGCAGGTCTTTCGTAATCTGCTCGACAACGCGCTGAAGCATA
CGCCGAGCGGAGGAGAAATCGTGCCGTCGCTCGTCGTCGGTCCGGATACGGTCCAGGTCCGTATCGCTGATACGGGCGCC
GGCATACCAGCCGATCGGCTCGAACGGATATTCGAACCGTTCCTGCAGATACGCCATCCATTGCATGCGCAAGCAGGCGG
CCTTGGGCTCGGTCTTTCCATCGCCCGCAGCATCGTGGTCATGCACCGAGGCGAGATCACGGCGTACAGCGACGGGCTGG
GCAAAGGCGCAACGTTTACCGTGACGTTGCCGCGACTTGCGCAAGCGCGACCTCGGGAACGAATCTTGCGCGACGCTGCG
CCGAGCGACACGTCGATCGAGGGCAGCGACGTACTGCTGGTCGAGGACGATGCCGATGCGCGCGATGCGCTCGCAACGAT
CTTGCGCCTGAAGCGCGCCGTGGTCCGCACGGCAAGCTCGGCCGAGGAGGCGCGCCTCGCGATCCGCGGCGGCGTGCCCG
ACCTGATCGTGTGCGATCTCACGATGCCTGAAGAGAGCGGAATCGACTTCGCAAGAACGCTGCGCCGGGACGGTGTCGAT
ATTCCGATGATCGCGCTCACGGGCCACGCGCGGGAAGAGGACATGCGCATGGCGACCGAGGCCGGCTTCGACGCGTACCT
GACCAAGCCGATCGATACGGCGCATCTCGTCGCGGCGATAGAAAAGCTCGTGCGCCGCTGA

Upstream 100 bases:

>100_bases
TCGGCGAGCGTACGGCCGACGCTCGCGCCCGGGACGACGGCCAAGTCCCACCATCGGGCAAATCGATCGAGCACGCATGC
GGACCTGAGAGCGAGAACAG

Downstream 100 bases:

>100_bases
ACGCGCGGGATGCGCGACGCGTGCGCCGCCGTATCGGCGGCCGCTCGCGAGCGGGAAGGCAGGTGACGATGACGGGTTTC
GTCGACGACGGCGCAGCGGC

Product: putative and unique signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 526; Mature: 525

Protein sequence:

>526_residues
MTTYLLPHPVESAEQARDRLERAVDAAELGTFHCPLPLDRLFWNARCKAHFWLDPDTPDDEINIDTFYRILHADDRASVR
AAVDAAVTHGGLFDVEYRTVSARGDVRWLRAKGSAHVGTDGRPVRLDGITIDISAQKRLERERDALIESERIQRFAAQSA
SESKDAFIAAVSHELRAPSTAILGWADMLGDAADDAAVVREGVAVIRRNILALTRLVDDLLDASRLGQGKFAIESAPVSI
AECLNAALQDVAPIAETKGVRIAEPGADDGLVSGDAARLEQVFRNLLDNALKHTPSGGEIVPSLVVGPDTVQVRIADTGA
GIPADRLERIFEPFLQIRHPLHAQAGGLGLGLSIARSIVVMHRGEITAYSDGLGKGATFTVTLPRLAQARPRERILRDAA
PSDTSIEGSDVLLVEDDADARDALATILRLKRAVVRTASSAEEARLAIRGGVPDLIVCDLTMPEESGIDFARTLRRDGVD
IPMIALTGHAREEDMRMATEAGFDAYLTKPIDTAHLVAAIEKLVRR

Sequences:

>Translated_526_residues
MTTYLLPHPVESAEQARDRLERAVDAAELGTFHCPLPLDRLFWNARCKAHFWLDPDTPDDEINIDTFYRILHADDRASVR
AAVDAAVTHGGLFDVEYRTVSARGDVRWLRAKGSAHVGTDGRPVRLDGITIDISAQKRLERERDALIESERIQRFAAQSA
SESKDAFIAAVSHELRAPSTAILGWADMLGDAADDAAVVREGVAVIRRNILALTRLVDDLLDASRLGQGKFAIESAPVSI
AECLNAALQDVAPIAETKGVRIAEPGADDGLVSGDAARLEQVFRNLLDNALKHTPSGGEIVPSLVVGPDTVQVRIADTGA
GIPADRLERIFEPFLQIRHPLHAQAGGLGLGLSIARSIVVMHRGEITAYSDGLGKGATFTVTLPRLAQARPRERILRDAA
PSDTSIEGSDVLLVEDDADARDALATILRLKRAVVRTASSAEEARLAIRGGVPDLIVCDLTMPEESGIDFARTLRRDGVD
IPMIALTGHAREEDMRMATEAGFDAYLTKPIDTAHLVAAIEKLVRR
>Mature_525_residues
TTYLLPHPVESAEQARDRLERAVDAAELGTFHCPLPLDRLFWNARCKAHFWLDPDTPDDEINIDTFYRILHADDRASVRA
AVDAAVTHGGLFDVEYRTVSARGDVRWLRAKGSAHVGTDGRPVRLDGITIDISAQKRLERERDALIESERIQRFAAQSAS
ESKDAFIAAVSHELRAPSTAILGWADMLGDAADDAAVVREGVAVIRRNILALTRLVDDLLDASRLGQGKFAIESAPVSIA
ECLNAALQDVAPIAETKGVRIAEPGADDGLVSGDAARLEQVFRNLLDNALKHTPSGGEIVPSLVVGPDTVQVRIADTGAG
IPADRLERIFEPFLQIRHPLHAQAGGLGLGLSIARSIVVMHRGEITAYSDGLGKGATFTVTLPRLAQARPRERILRDAAP
SDTSIEGSDVLLVEDDADARDALATILRLKRAVVRTASSAEEARLAIRGGVPDLIVCDLTMPEESGIDFARTLRRDGVDI
PMIALTGHAREEDMRMATEAGFDAYLTKPIDTAHLVAAIEKLVRR

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=389, Percent_Identity=30.5912596401028, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI145693157, Length=269, Percent_Identity=32.7137546468402, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI87081816, Length=377, Percent_Identity=29.4429708222812, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1786912, Length=246, Percent_Identity=34.5528455284553, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1788713, Length=390, Percent_Identity=25.1282051282051, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788393, Length=218, Percent_Identity=34.8623853211009, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1789149, Length=229, Percent_Identity=32.7510917030568, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1786783, Length=264, Percent_Identity=29.9242424242424, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=28.6995515695067, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788549, Length=224, Percent_Identity=30.3571428571429, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=31.1926605504587, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1787894, Length=230, Percent_Identity=30.8695652173913, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790861, Length=255, Percent_Identity=29.4117647058824, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1790346, Length=226, Percent_Identity=28.3185840707965, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=35.5932203389831, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87082128, Length=248, Percent_Identity=26.6129032258064, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787375, Length=116, Percent_Identity=32.7586206896552, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56943; Mature: 56812

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTYLLPHPVESAEQARDRLERAVDAAELGTFHCPLPLDRLFWNARCKAHFWLDPDTPDD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHCCCEEEEEEECCCCCCC
EINIDTFYRILHADDRASVRAAVDAAVTHGGLFDVEYRTVSARGDVRWLRAKGSAHVGTD
CCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEEEEECCCCEEEEEECCCCCCCCC
GRPVRLDGITIDISAQKRLERERDALIESERIQRFAAQSASESKDAFIAAVSHELRAPST
CCEEEECCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCH
AILGWADMLGDAADDAAVVREGVAVIRRNILALTRLVDDLLDASRLGQGKFAIESAPVSI
HEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHH
AECLNAALQDVAPIAETKGVRIAEPGADDGLVSGDAARLEQVFRNLLDNALKHTPSGGEI
HHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
VPSLVVGPDTVQVRIADTGAGIPADRLERIFEPFLQIRHPLHAQAGGLGLGLSIARSIVV
CCEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
MHRGEITAYSDGLGKGATFTVTLPRLAQARPRERILRDAAPSDTSIEGSDVLLVEDDADA
EECCCEEEECCCCCCCCEEEEECCHHHCCCCHHHHHHCCCCCCCCCCCCEEEEEECCCCH
RDALATILRLKRAVVRTASSAEEARLAIRGGVPDLIVCDLTMPEESGIDFARTLRRDGVD
HHHHHHHHHHHHHHHHHCCCHHHHEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHCCCC
IPMIALTGHAREEDMRMATEAGFDAYLTKPIDTAHLVAAIEKLVRR
CEEEEEECCCCHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTYLLPHPVESAEQARDRLERAVDAAELGTFHCPLPLDRLFWNARCKAHFWLDPDTPDD
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHCCCEEEEEEECCCCCCC
EINIDTFYRILHADDRASVRAAVDAAVTHGGLFDVEYRTVSARGDVRWLRAKGSAHVGTD
CCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEEEEECCCCEEEEEECCCCCCCCC
GRPVRLDGITIDISAQKRLERERDALIESERIQRFAAQSASESKDAFIAAVSHELRAPST
CCEEEECCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCH
AILGWADMLGDAADDAAVVREGVAVIRRNILALTRLVDDLLDASRLGQGKFAIESAPVSI
HEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHH
AECLNAALQDVAPIAETKGVRIAEPGADDGLVSGDAARLEQVFRNLLDNALKHTPSGGEI
HHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
VPSLVVGPDTVQVRIADTGAGIPADRLERIFEPFLQIRHPLHAQAGGLGLGLSIARSIVV
CCEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
MHRGEITAYSDGLGKGATFTVTLPRLAQARPRERILRDAAPSDTSIEGSDVLLVEDDADA
EECCCEEEECCCCCCCCEEEEECCHHHCCCCHHHHHHCCCCCCCCCCCCEEEEEECCCCH
RDALATILRLKRAVVRTASSAEEARLAIRGGVPDLIVCDLTMPEESGIDFARTLRRDGVD
HHHHHHHHHHHHHHHHHCCCHHHHEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHCCCC
IPMIALTGHAREEDMRMATEAGFDAYLTKPIDTAHLVAAIEKLVRR
CEEEEEECCCCHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]