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The map label for this gene is 189352575

Identifier: 189352575

GI number: 189352575

Start: 647799

End: 648194

Strand: Direct

Name: 189352575

Synonym: BMULJ_03806

Alternate gene names: NA

Gene position: 647799-648194 (Clockwise)

Preceding gene: 189352574

Following gene: 189352576

Centisome position: 26.19

GC content: 57.58

Gene sequence:

>396_bases
TTGTGTCACCGCGCTGCATTGCGCAGGTTGGCAGCATGGTCAGCGAGATTCGCAAAGATCCCGGACGCGACGCTAGTGTA
CAACAACAGCCCGTCGTTCGGCTGGACGCCGAACTTCTGCCGGCAGGCGTATGAGGCGATGAAAGTCGAGGGTAAGGACG
TATTGGCCTATGAACGCGGCCGACTGATGAGCGTAGATACGATCAGACCACACTGGCGAAGCTGCCACTCCAACTCGCCA
CTCGCGGCTCGTGACAGAGTTTTCTGGCTTGAAAGCGCTTTCGCGACTGCTTTGTCAGAAAACCGACCAGCGCGTGCACG
TTTGCCGCGGGAAAACCCGGGGCACCCTAGATGTTGCATGCAGCGTGGCGCCACTATATCTTGTGCTTATAAGTGA

Upstream 100 bases:

>100_bases
GGCAATGGCTACGTCGTCATCAAGCGCGACGGCTGGATCCCAAGCGCCTGCCGAGCAACCCGTTACAGTTCCTCGCCGGC
GAAGGACGTAGCGTGTTCGA

Downstream 100 bases:

>100_bases
ACCAAACGCAAAATATTGTGGACAATTTGGGCGGTGTCTGCTTATACGGTATCTGGGCGGATTTTGATGGGTCGGTGTTT
ATGCAGGGCAGGCGCCGACC

Product: hypothetical protein

Products: NA

Alternate protein names: ICL; Isocitrase; Isocitratase [H]

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MCHRAALRRLAAWSARFAKIPDATLVYNNSPSFGWTPNFCRQAYEAMKVEGKDVLAYERGRLMSVDTIRPHWRSCHSNSP
LAARDRVFWLESAFATALSENRPARARLPRENPGHPRCCMQRGATISCAYK

Sequences:

>Translated_131_residues
MCHRAALRRLAAWSARFAKIPDATLVYNNSPSFGWTPNFCRQAYEAMKVEGKDVLAYERGRLMSVDTIRPHWRSCHSNSP
LAARDRVFWLESAFATALSENRPARARLPRENPGHPRCCMQRGATISCAYK
>Mature_131_residues
MCHRAALRRLAAWSARFAKIPDATLVYNNSPSFGWTPNFCRQAYEAMKVEGKDVLAYERGRLMSVDTIRPHWRSCHSNSP
LAARDRVFWLESAFATALSENRPARARLPRENPGHPRCCMQRGATISCAYK

Specific function: Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle. May be involved in the assimilation of one-carbon compounds via the isocitrate lyase- positive serine pathway [H]

COG id: COG2224

COG function: function code C; Isocitrate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006254
- InterPro:   IPR000918
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00463 ICL [H]

EC number: =4.1.3.1 [H]

Molecular weight: Translated: 14927; Mature: 14927

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCHRAALRRLAAWSARFAKIPDATLVYNNSPSFGWTPNFCRQAYEAMKVEGKDVLAYERG
CCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCC
RLMSVDTIRPHWRSCHSNSPLAARDRVFWLESAFATALSENRPARARLPRENPGHPRCCM
CEEEECCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
QRGATISCAYK
HCCCEEEEECC
>Mature Secondary Structure
MCHRAALRRLAAWSARFAKIPDATLVYNNSPSFGWTPNFCRQAYEAMKVEGKDVLAYERG
CCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCC
RLMSVDTIRPHWRSCHSNSPLAARDRVFWLESAFATALSENRPARARLPRENPGHPRCCM
CEEEECCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
QRGATISCAYK
HCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]