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The map label for this gene is ytnA [H]

Identifier: 189352540

GI number: 189352540

Start: 604063

End: 605487

Strand: Direct

Name: ytnA [H]

Synonym: BMULJ_03768

Alternate gene names: 189352540

Gene position: 604063-605487 (Clockwise)

Preceding gene: 189352539

Following gene: 189352542

Centisome position: 24.42

GC content: 60.42

Gene sequence:

>1425_bases
ATGCAACCAGCCGAAATCGGCACCCCTCTCAGGCGGACGCTCGGCGCACGTCACATCAATCTCATGGCGCTAGGCGCGAC
GATCGGCGTCGGCCTATTCCTCGGTTCCGCGACGGCGATCCGGCTTGCCGGACCGTCCATCCTGCTCGGCTACGCGTTCG
TGGGCGTATTCGTCTTCTTCGTGATGCGGGCGCTCGGAGAGATGGCGGTTGCGCACCCGGTGGCTGGCTCGTTCAATCGC
TACGCATACGAGTACATTGGCCCGCGCGCGGGTTTTGTTACTGGATGGACCTACTGGTTCATGTGGATCCTGTGCATCAT
GGCCGAGGTGACGGCCGTCGCCATCTACATGAAGTTCTGGTTTCCGGGCATGCCGGCGTGGGTGTGGTCGCTCGCAGCTC
TTGCTACGATGGGCCTACTCAACTTTGTGGCGGTACGCGCGTTCGGCGAGCTCGAATTCTGGTTCGCGGCGATCAAGATC
GTCACGATCGTGTTCATGATTCTCTCGGGCATCGGCATCATCGGCTTCGGGTTTGGCAACGGCGGTGTAGCGACTGGAAT
CGGCAACCTTTGGCGGCATGGCGGCTTCCTGCCGAATGGCATGTGGGGTTTGGCGTCGGCCATACCAATGGTGGTTTTCG
CCTACCTCGGCGTGGAGATCATCGGGCTCACGGCGGGCGAGACGAAGAATCCGGAAAAATCGCTCGCACGCGCTGTCAAT
TCGGTGTTCTGGCGCATTGCGATCTTCTACATCGGCGCGTTGTTCATCATTATGTCCCTATATCCATGGAATGCGATTGG
CACGCAGGGCAGCCCGTTTGTGCTGACGTTCGAGCGGCTCGGCATCCGCGGCGCGGCCGGCATCATTAACTTCGTGGTGC
TTTCGGCGGCGCTTTCGTCGTGCAACAGCGGTATCTTCGGTACGGCGCGCATCGTGTTCAATCTGGCTCAGCAGGGGCAG
GCGCCGCGCATTTTTGCGCACACGTCAAAGAGCGGAATTCCCGCATGCGCGGTTGTGCTGACGCTTGTTGCGGCACTTCT
CGGCGTGCTGCTCAATTATGTCGCCCCGAAGGGTCTGTTCGAATGGTTGACCGCGATCGGCACGTTTGCCGGGCTCTTCT
CGTGGGCCATAATTCTCGTCGCGCATTACAGGTTCAGGCGGCAGCGCGTAGCGCAGGACAACCGCATGTTAATGCCGTGG
TGGCCATACAGCTCGTACTGCACCCTTGCGTTTCTGGCGGTCCTGGTCGCTTTCATGCTGAAGTTTGACGAGACGCGCGT
CGCCGTTATCGTCGGTCCGCTCTGGCTCGCATTTCTCTGGATTGTGTACGGGTTGTCGGCGAAAAATGGCGCCTCTCGTC
AAGGCGTGCCATCGCCGAGCGCTTCGTTCGCTGTAGAGGGCGTAACGCGCGACATACGGGACTAG

Upstream 100 bases:

>100_bases
GCCAGACGTCCGACGCCGGCTGGAGGCTCGCGCTCGTCCCGGGGAGCGTCAATGCCGCATCGCAAACGGGACGCATTCGT
TAATAATTAAGGAGACAGAC

Downstream 100 bases:

>100_bases
TCTTCGCTTATTACATAGCCATGCAGGCACCGCGTTTCCTGCCCGATCCGGCAGACGTGCTTTAACTCAATGCGGTGCTT
GTCGCGGTTGATCTGCGGTG

Product: AAT family amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MQPAEIGTPLRRTLGARHINLMALGATIGVGLFLGSATAIRLAGPSILLGYAFVGVFVFFVMRALGEMAVAHPVAGSFNR
YAYEYIGPRAGFVTGWTYWFMWILCIMAEVTAVAIYMKFWFPGMPAWVWSLAALATMGLLNFVAVRAFGELEFWFAAIKI
VTIVFMILSGIGIIGFGFGNGGVATGIGNLWRHGGFLPNGMWGLASAIPMVVFAYLGVEIIGLTAGETKNPEKSLARAVN
SVFWRIAIFYIGALFIIMSLYPWNAIGTQGSPFVLTFERLGIRGAAGIINFVVLSAALSSCNSGIFGTARIVFNLAQQGQ
APRIFAHTSKSGIPACAVVLTLVAALLGVLLNYVAPKGLFEWLTAIGTFAGLFSWAIILVAHYRFRRQRVAQDNRMLMPW
WPYSSYCTLAFLAVLVAFMLKFDETRVAVIVGPLWLAFLWIVYGLSAKNGASRQGVPSPSASFAVEGVTRDIRD

Sequences:

>Translated_474_residues
MQPAEIGTPLRRTLGARHINLMALGATIGVGLFLGSATAIRLAGPSILLGYAFVGVFVFFVMRALGEMAVAHPVAGSFNR
YAYEYIGPRAGFVTGWTYWFMWILCIMAEVTAVAIYMKFWFPGMPAWVWSLAALATMGLLNFVAVRAFGELEFWFAAIKI
VTIVFMILSGIGIIGFGFGNGGVATGIGNLWRHGGFLPNGMWGLASAIPMVVFAYLGVEIIGLTAGETKNPEKSLARAVN
SVFWRIAIFYIGALFIIMSLYPWNAIGTQGSPFVLTFERLGIRGAAGIINFVVLSAALSSCNSGIFGTARIVFNLAQQGQ
APRIFAHTSKSGIPACAVVLTLVAALLGVLLNYVAPKGLFEWLTAIGTFAGLFSWAIILVAHYRFRRQRVAQDNRMLMPW
WPYSSYCTLAFLAVLVAFMLKFDETRVAVIVGPLWLAFLWIVYGLSAKNGASRQGVPSPSASFAVEGVTRDIRD
>Mature_474_residues
MQPAEIGTPLRRTLGARHINLMALGATIGVGLFLGSATAIRLAGPSILLGYAFVGVFVFFVMRALGEMAVAHPVAGSFNR
YAYEYIGPRAGFVTGWTYWFMWILCIMAEVTAVAIYMKFWFPGMPAWVWSLAALATMGLLNFVAVRAFGELEFWFAAIKI
VTIVFMILSGIGIIGFGFGNGGVATGIGNLWRHGGFLPNGMWGLASAIPMVVFAYLGVEIIGLTAGETKNPEKSLARAVN
SVFWRIAIFYIGALFIIMSLYPWNAIGTQGSPFVLTFERLGIRGAAGIINFVVLSAALSSCNSGIFGTARIVFNLAQQGQ
APRIFAHTSKSGIPACAVVLTLVAALLGVLLNYVAPKGLFEWLTAIGTFAGLFSWAIILVAHYRFRRQRVAQDNRMLMPW
WPYSSYCTLAFLAVLVAFMLKFDETRVAVIVGPLWLAFLWIVYGLSAKNGASRQGVPSPSASFAVEGVTRDIRD

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=413, Percent_Identity=23.2445520581114, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI110347453, Length=361, Percent_Identity=24.3767313019391, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI181337167, Length=343, Percent_Identity=22.7405247813411, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI258645169, Length=426, Percent_Identity=21.3615023474178, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI48994972, Length=460, Percent_Identity=45.8695652173913, Blast_Score=399, Evalue=1e-112,
Organism=Escherichia coli, GI1786602, Length=453, Percent_Identity=47.9028697571744, Blast_Score=390, Evalue=1e-110,
Organism=Escherichia coli, GI1786789, Length=441, Percent_Identity=42.8571428571429, Blast_Score=377, Evalue=1e-105,
Organism=Escherichia coli, GI1786302, Length=456, Percent_Identity=42.9824561403509, Blast_Score=373, Evalue=1e-104,
Organism=Escherichia coli, GI1790653, Length=438, Percent_Identity=43.8356164383562, Blast_Score=367, Evalue=1e-103,
Organism=Escherichia coli, GI87081915, Length=401, Percent_Identity=39.6508728179551, Blast_Score=308, Evalue=5e-85,
Organism=Escherichia coli, GI87081708, Length=464, Percent_Identity=36.6379310344828, Blast_Score=295, Evalue=6e-81,
Organism=Escherichia coli, GI1789017, Length=433, Percent_Identity=35.796766743649, Blast_Score=281, Evalue=8e-77,
Organism=Escherichia coli, GI1788480, Length=397, Percent_Identity=38.7909319899244, Blast_Score=278, Evalue=5e-76,
Organism=Escherichia coli, GI87082023, Length=408, Percent_Identity=24.0196078431373, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87081869, Length=459, Percent_Identity=20.9150326797386, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17532491, Length=408, Percent_Identity=25.7352941176471, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17531343, Length=407, Percent_Identity=24.3243243243243, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17533459, Length=439, Percent_Identity=23.4624145785877, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324061, Length=442, Percent_Identity=33.710407239819, Blast_Score=231, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6320772, Length=454, Percent_Identity=33.0396475770925, Blast_Score=222, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6322892, Length=401, Percent_Identity=32.9177057356608, Blast_Score=207, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6324924, Length=405, Percent_Identity=31.6049382716049, Blast_Score=202, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6324990, Length=452, Percent_Identity=31.6371681415929, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6321629, Length=406, Percent_Identity=30.0492610837438, Blast_Score=197, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6324553, Length=397, Percent_Identity=32.2418136020151, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6324059, Length=436, Percent_Identity=30.9633027522936, Blast_Score=190, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6320251, Length=400, Percent_Identity=30.75, Blast_Score=186, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6319824, Length=398, Percent_Identity=29.1457286432161, Blast_Score=185, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6319542, Length=402, Percent_Identity=29.3532338308458, Blast_Score=183, Evalue=6e-47,
Organism=Saccharomyces cerevisiae, GI6322967, Length=400, Percent_Identity=30.5, Blast_Score=179, Evalue=6e-46,
Organism=Saccharomyces cerevisiae, GI6320717, Length=412, Percent_Identity=29.126213592233, Blast_Score=179, Evalue=8e-46,
Organism=Saccharomyces cerevisiae, GI6319543, Length=406, Percent_Identity=27.0935960591133, Blast_Score=172, Evalue=8e-44,
Organism=Saccharomyces cerevisiae, GI6321053, Length=441, Percent_Identity=28.3446712018141, Blast_Score=170, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6324981, Length=398, Percent_Identity=29.3969849246231, Blast_Score=164, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6319608, Length=428, Percent_Identity=26.4018691588785, Blast_Score=154, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6320364, Length=498, Percent_Identity=23.0923694779116, Blast_Score=111, Evalue=3e-25,
Organism=Drosophila melanogaster, GI221512776, Length=334, Percent_Identity=21.5568862275449, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24666159, Length=334, Percent_Identity=21.5568862275449, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51414; Mature: 51414

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPAEIGTPLRRTLGARHINLMALGATIGVGLFLGSATAIRLAGPSILLGYAFVGVFVFF
CCCCCCCCHHHHHHCCCHHHHEEHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHH
VMRALGEMAVAHPVAGSFNRYAYEYIGPRAGFVTGWTYWFMWILCIMAEVTAVAIYMKFW
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPGMPAWVWSLAALATMGLLNFVAVRAFGELEFWFAAIKIVTIVFMILSGIGIIGFGFGN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
GGVATGIGNLWRHGGFLPNGMWGLASAIPMVVFAYLGVEIIGLTAGETKNPEKSLARAVN
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHH
SVFWRIAIFYIGALFIIMSLYPWNAIGTQGSPFVLTFERLGIRGAAGIINFVVLSAALSS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHH
CNSGIFGTARIVFNLAQQGQAPRIFAHTSKSGIPACAVVLTLVAALLGVLLNYVAPKGLF
CCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHH
EWLTAIGTFAGLFSWAIILVAHYRFRRQRVAQDNRMLMPWWPYSSYCTLAFLAVLVAFML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHH
KFDETRVAVIVGPLWLAFLWIVYGLSAKNGASRQGVPSPSASFAVEGVTRDIRD
HCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MQPAEIGTPLRRTLGARHINLMALGATIGVGLFLGSATAIRLAGPSILLGYAFVGVFVFF
CCCCCCCCHHHHHHCCCHHHHEEHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHH
VMRALGEMAVAHPVAGSFNRYAYEYIGPRAGFVTGWTYWFMWILCIMAEVTAVAIYMKFW
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPGMPAWVWSLAALATMGLLNFVAVRAFGELEFWFAAIKIVTIVFMILSGIGIIGFGFGN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
GGVATGIGNLWRHGGFLPNGMWGLASAIPMVVFAYLGVEIIGLTAGETKNPEKSLARAVN
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHH
SVFWRIAIFYIGALFIIMSLYPWNAIGTQGSPFVLTFERLGIRGAAGIINFVVLSAALSS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHH
CNSGIFGTARIVFNLAQQGQAPRIFAHTSKSGIPACAVVLTLVAALLGVLLNYVAPKGLF
CCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHH
EWLTAIGTFAGLFSWAIILVAHYRFRRQRVAQDNRMLMPWWPYSSYCTLAFLAVLVAFML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHH
KFDETRVAVIVGPLWLAFLWIVYGLSAKNGASRQGVPSPSASFAVEGVTRDIRD
HCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]