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The map label for this gene is gcp [H]

Identifier: 189352479

GI number: 189352479

Start: 529705

End: 530745

Strand: Reverse

Name: gcp [H]

Synonym: BMULJ_03698

Alternate gene names: 189352479

Gene position: 530745-529705 (Counterclockwise)

Preceding gene: 189352485

Following gene: 189352474

Centisome position: 21.46

GC content: 68.59

Gene sequence:

>1041_bases
ATGCTCGTTCTCGGCATCGAAAGCTCCTGCGACGAAACCGGTCTCGCGCTCTACGACACGCAGCGCGGCCTGCTCGCGCA
CGCGCTTCATTCGCAGATCGCGATGCACCGCGACTATGGCGGCGTCGTGCCCGAGCTCGCCTCGCGCGATCACATCCGGC
GCGCGCTGCCGCTGCTCGAGGAAGTGATCGCGAAAAGCGGCGCGCGCCGCGAAGACATCGACGCGATCGCGTTCACGCAG
GGCCCGGGGCTCGCCGGCGCGCTGCTCGTGGGCGCGAGCATCGCGAACGCGCTCGCGCTCGCATGGAACAAGCCGACCGT
CGGCATCCACCATCTCGAAGGCCATCTGCTGTCGCCGCTACTCGTCGCGGAACCGCCGCCGTTCCCGTTCGTCGCGCTGC
TCGTGTCGGGCGGTCATACGCAACTGATGCGCGTGACCGACGTCGGCGTGTACGAGACGCTCGGCGAAACGCTCGACGAC
GCGGCTGGCGAAGCGTTCGACAAGACGGCGAAGCTGATCGGCCTCGGCTATCCGGGCGGCCCGGAAGTATCGAAGCTCGC
GGAAACGGGCACGCCGGGCGCCGTCGTGCTGCCGCGCCCGATGCTGCATTCGGGCGATCTCGATTTCAGCTTCAGCGGCT
TGAAAACGGCCGTGCTCACGCAGATGAAGAAGTTCGAAGCGGCGCAGTTGTCGGGCGATGCGCTGGCGCGCGCGAAGGCC
GATCTCGCGCGCGGCTTCGTCGACGCGGCCGTCGACGTGCTCGTCGCCAAATCGCTCGCCGCGTTGAAAAAGACCAAGCT
CAAGCGGCTCGTCGTCGCGGGCGGCGTGGGCGCGAACCGTCAGTTGCGCGCCGCGTTGTCGGCCGCGGCCGCGAAGCGCG
GTTTCGACGTGCACTATCCCGATCTCGCGCTGTGCACCGACAACGGCGCGATGATCGCGCTGGCGGGTGCGCTGCGGCTC
GCACGCTGGCCCGAGCAGGCCAACGTCGACTATGCATTCACGGTGAAGCCGCGCTGGGATCTCGCGTCGCTCGCACGCTG
A

Upstream 100 bases:

>100_bases
CGGGGCCCGGCGCCGGCGGCGGCCGGCCCTTGCCTGCTATACTTTCCGGTTACTCGATATTCCTGCGGCGCGCTCGACGC
AGCGCGCCGCGCCCGCACCC

Downstream 100 bases:

>100_bases
AGCGCGCGCCGCGCGATCCGCGCAGATGAAAAAGGCCGCTGCTGCGGCCTTTTCTTCATTCGACGCTCGCGCCGTGCCGA
AGCCGGCGCGTAGTCGGTCG

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MLVLGIESSCDETGLALYDTQRGLLAHALHSQIAMHRDYGGVVPELASRDHIRRALPLLEEVIAKSGARREDIDAIAFTQ
GPGLAGALLVGASIANALALAWNKPTVGIHHLEGHLLSPLLVAEPPPFPFVALLVSGGHTQLMRVTDVGVYETLGETLDD
AAGEAFDKTAKLIGLGYPGGPEVSKLAETGTPGAVVLPRPMLHSGDLDFSFSGLKTAVLTQMKKFEAAQLSGDALARAKA
DLARGFVDAAVDVLVAKSLAALKKTKLKRLVVAGGVGANRQLRAALSAAAAKRGFDVHYPDLALCTDNGAMIALAGALRL
ARWPEQANVDYAFTVKPRWDLASLAR

Sequences:

>Translated_346_residues
MLVLGIESSCDETGLALYDTQRGLLAHALHSQIAMHRDYGGVVPELASRDHIRRALPLLEEVIAKSGARREDIDAIAFTQ
GPGLAGALLVGASIANALALAWNKPTVGIHHLEGHLLSPLLVAEPPPFPFVALLVSGGHTQLMRVTDVGVYETLGETLDD
AAGEAFDKTAKLIGLGYPGGPEVSKLAETGTPGAVVLPRPMLHSGDLDFSFSGLKTAVLTQMKKFEAAQLSGDALARAKA
DLARGFVDAAVDVLVAKSLAALKKTKLKRLVVAGGVGANRQLRAALSAAAAKRGFDVHYPDLALCTDNGAMIALAGALRL
ARWPEQANVDYAFTVKPRWDLASLAR
>Mature_346_residues
MLVLGIESSCDETGLALYDTQRGLLAHALHSQIAMHRDYGGVVPELASRDHIRRALPLLEEVIAKSGARREDIDAIAFTQ
GPGLAGALLVGASIANALALAWNKPTVGIHHLEGHLLSPLLVAEPPPFPFVALLVSGGHTQLMRVTDVGVYETLGETLDD
AAGEAFDKTAKLIGLGYPGGPEVSKLAETGTPGAVVLPRPMLHSGDLDFSFSGLKTAVLTQMKKFEAAQLSGDALARAKA
DLARGFVDAAVDVLVAKSLAALKKTKLKRLVVAGGVGANRQLRAALSAAAAKRGFDVHYPDLALCTDNGAMIALAGALRL
ARWPEQANVDYAFTVKPRWDLASLAR

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=335, Percent_Identity=34.6268656716418, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI8923380, Length=317, Percent_Identity=29.9684542586751, Blast_Score=124, Evalue=9e-29,
Organism=Escherichia coli, GI1789445, Length=345, Percent_Identity=56.8115942028986, Blast_Score=386, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17557464, Length=335, Percent_Identity=32.2388059701493, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI71995670, Length=329, Percent_Identity=31.6109422492401, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320099, Length=340, Percent_Identity=33.2352941176471, Blast_Score=166, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6322891, Length=349, Percent_Identity=25.5014326647564, Blast_Score=103, Evalue=5e-23,
Organism=Drosophila melanogaster, GI20129063, Length=338, Percent_Identity=33.1360946745562, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI21357207, Length=326, Percent_Identity=29.1411042944785, Blast_Score=130, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36365; Mature: 36365

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVLGIESSCDETGLALYDTQRGLLAHALHSQIAMHRDYGGVVPELASRDHIRRALPLLE
CEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
EVIAKSGARREDIDAIAFTQGPGLAGALLVGASIANALALAWNKPTVGIHHLEGHLLSPL
HHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHEEECCCCCEEEECCCHHHCCE
LVAEPPPFPFVALLVSGGHTQLMRVTDVGVYETLGETLDDAAGEAFDKTAKLIGLGYPGG
EECCCCCCCEEEEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
PEVSKLAETGTPGAVVLPRPMLHSGDLDFSFSGLKTAVLTQMKKFEAAQLSGDALARAKA
CCHHHHHHCCCCCEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
DLARGFVDAAVDVLVAKSLAALKKTKLKRLVVAGGVGANRQLRAALSAAAAKRGFDVHYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHCCCCCCCC
DLALCTDNGAMIALAGALRLARWPEQANVDYAFTVKPRWDLASLAR
CEEEEECCCCEEEHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHCC
>Mature Secondary Structure
MLVLGIESSCDETGLALYDTQRGLLAHALHSQIAMHRDYGGVVPELASRDHIRRALPLLE
CEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
EVIAKSGARREDIDAIAFTQGPGLAGALLVGASIANALALAWNKPTVGIHHLEGHLLSPL
HHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHEEECCCCCEEEECCCHHHCCE
LVAEPPPFPFVALLVSGGHTQLMRVTDVGVYETLGETLDDAAGEAFDKTAKLIGLGYPGG
EECCCCCCCEEEEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
PEVSKLAETGTPGAVVLPRPMLHSGDLDFSFSGLKTAVLTQMKKFEAAQLSGDALARAKA
CCHHHHHHCCCCCEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
DLARGFVDAAVDVLVAKSLAALKKTKLKRLVVAGGVGANRQLRAALSAAAAKRGFDVHYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHCCCCCCCC
DLALCTDNGAMIALAGALRLARWPEQANVDYAFTVKPRWDLASLAR
CEEEEECCCCEEEHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA