BacMap

Definition	Burkholderia multivorans ATCC 17616 chromosome 2, complete genome.
Accession	NC_010805
Length	2,473,162

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The map label for this gene is fbp [H]

Identifier: 189352390

GI number: 189352390

Start: 447845

End: 448186

Strand: Reverse

Name: fbp [H]

Synonym: BMULJ_03609

Alternate gene names: 189352390

Gene position: 448186-447845 (Counterclockwise)

Preceding gene: 189352394

Following gene: 189352389

Centisome position: 18.12

GC content: 65.5

Gene sequence:

>342_bases
ATGTCTGTGATCACGACCGCATCGGGCCTCAAATACGAAGACCTGACCGAAGGCACCGGCGCGGAAGCGCAAGCGGGCCA
GACCGTCAGCGTCCACTACACGGGCTGGCTCACCGACGGTCAGAAGTTCGATTCGAGCAAGGACCGCAACGATCCGTTCG
CGTTCGTGCTCGGCGGCGGCATGGTCATCAAGGGCTGGGACGAAGGCGTGCAAGGCATGAAGGTCGGCGGCGTGCGTCGC
CTGACGATTCCGCCGCAACTCGGCTACGGCGTGCGCGGCGCGGGCGGCGTGATTCCGCCGAACGCGACGCTCGTGTTCGA
AGTCGAACTGCTCGCCGTCTGA

Upstream 100 bases:

>100_bases
GCGCGCGATCGTCGCCGCTCGCGCCGCCGGCCGCGTGCGACGGCGCATGCCGCGCTCGCCTACAATATCGGCTTTATCCC
ATCCCTTTTCAGGAGAAGTC

Downstream 100 bases:

>100_bases
CACACGCGCCGCCGGCCGCCGCTCCGTGACGATGGAACGTATCGCCTCGCCCGCCGTGTCGCTGCGCCGCTACGACGCGT
GCGAAGCGTCGGATGTGCAC

Product: peptidylprolyl isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 113; Mature: 112

Protein sequence:

>113_residues
MSVITTASGLKYEDLTEGTGAEAQAGQTVSVHYTGWLTDGQKFDSSKDRNDPFAFVLGGGMVIKGWDEGVQGMKVGGVRR
LTIPPQLGYGVRGAGGVIPPNATLVFEVELLAV

Sequences:

>Translated_113_residues
MSVITTASGLKYEDLTEGTGAEAQAGQTVSVHYTGWLTDGQKFDSSKDRNDPFAFVLGGGMVIKGWDEGVQGMKVGGVRR
LTIPPQLGYGVRGAGGVIPPNATLVFEVELLAV
>Mature_112_residues
SVITTASGLKYEDLTEGTGAEAQAGQTVSVHYTGWLTDGQKFDSSKDRNDPFAFVLGGGMVIKGWDEGVQGMKVGGVRRL
TIPPQLGYGVRGAGGVIPPNATLVFEVELLAV

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cytoplasm And Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI17149836, Length=106, Percent_Identity=54.7169811320755, Blast_Score=116, Evalue=5e-27,
Organism=Homo sapiens, GI4503725, Length=106, Percent_Identity=54.7169811320755, Blast_Score=116, Evalue=5e-27,
Organism=Homo sapiens, GI4503729, Length=96, Percent_Identity=59.375, Blast_Score=111, Evalue=1e-25,
Organism=Homo sapiens, GI4758380, Length=106, Percent_Identity=50.9433962264151, Blast_Score=108, Evalue=6e-25,
Organism=Homo sapiens, GI206725530, Length=92, Percent_Identity=56.5217391304348, Blast_Score=104, Evalue=1e-23,
Organism=Homo sapiens, GI17149844, Length=92, Percent_Identity=56.5217391304348, Blast_Score=104, Evalue=1e-23,
Organism=Homo sapiens, GI17149842, Length=92, Percent_Identity=56.5217391304348, Blast_Score=104, Evalue=1e-23,
Organism=Homo sapiens, GI224809331, Length=95, Percent_Identity=53.6842105263158, Blast_Score=99, Evalue=8e-22,
Organism=Homo sapiens, GI192448443, Length=92, Percent_Identity=54.3478260869565, Blast_Score=97, Evalue=3e-21,
Organism=Homo sapiens, GI224809329, Length=95, Percent_Identity=53.6842105263158, Blast_Score=97, Evalue=3e-21,
Organism=Homo sapiens, GI224809327, Length=95, Percent_Identity=53.6842105263158, Blast_Score=97, Evalue=3e-21,
Organism=Homo sapiens, GI4758384, Length=95, Percent_Identity=53.6842105263158, Blast_Score=97, Evalue=3e-21,
Organism=Homo sapiens, GI33469985, Length=91, Percent_Identity=46.1538461538462, Blast_Score=87, Evalue=4e-18,
Organism=Homo sapiens, GI206725547, Length=100, Percent_Identity=45, Blast_Score=85, Evalue=1e-17,
Organism=Homo sapiens, GI8923659, Length=95, Percent_Identity=45.2631578947368, Blast_Score=82, Evalue=7e-17,
Organism=Homo sapiens, GI31317231, Length=101, Percent_Identity=45.5445544554455, Blast_Score=82, Evalue=8e-17,
Organism=Homo sapiens, GI150010552, Length=106, Percent_Identity=40.5660377358491, Blast_Score=78, Evalue=2e-15,
Organism=Homo sapiens, GI4503727, Length=98, Percent_Identity=42.8571428571429, Blast_Score=74, Evalue=3e-14,
Organism=Homo sapiens, GI7706131, Length=97, Percent_Identity=40.2061855670103, Blast_Score=73, Evalue=6e-14,
Organism=Homo sapiens, GI17149839, Length=79, Percent_Identity=45.5696202531646, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87082390, Length=111, Percent_Identity=50.4504504504504, Blast_Score=98, Evalue=2e-22,
Organism=Escherichia coli, GI1789745, Length=111, Percent_Identity=48.6486486486487, Blast_Score=90, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17540882, Length=97, Percent_Identity=52.5773195876289, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71993519, Length=106, Percent_Identity=53.7735849056604, Blast_Score=104, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17561782, Length=96, Percent_Identity=54.1666666666667, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17561778, Length=94, Percent_Identity=46.8085106382979, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71993555, Length=68, Percent_Identity=51.4705882352941, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17506169, Length=109, Percent_Identity=37.6146788990826, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17506167, Length=109, Percent_Identity=37.6146788990826, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17561780, Length=89, Percent_Identity=41.5730337078652, Blast_Score=65, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6324194, Length=105, Percent_Identity=53.3333333333333, Blast_Score=106, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6320727, Length=99, Percent_Identity=56.5656565656566, Blast_Score=102, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6323566, Length=105, Percent_Identity=46.6666666666667, Blast_Score=86, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323482, Length=105, Percent_Identity=44.7619047619048, Blast_Score=84, Evalue=5e-18,
Organism=Drosophila melanogaster, GI281363946, Length=113, Percent_Identity=53.9823008849557, Blast_Score=123, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17352457, Length=113, Percent_Identity=53.9823008849557, Blast_Score=123, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24655568, Length=90, Percent_Identity=60, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24647110, Length=109, Percent_Identity=55.045871559633, Blast_Score=110, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24583150, Length=105, Percent_Identity=53.3333333333333, Blast_Score=106, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21356629, Length=98, Percent_Identity=56.1224489795918, Blast_Score=95, Evalue=7e-21,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 11843; Mature: 11711

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVITTASGLKYEDLTEGTGAEAQAGQTVSVHYTGWLTDGQKFDSSKDRNDPFAFVLGGG
CCEEECCCCCEECCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCEEEEEECC
MVIKGWDEGVQGMKVGGVRRLTIPPQLGYGVRGAGGVIPPNATLVFEVELLAV
EEEECCCCCCCCEEECCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEEC
>Mature Secondary Structure 
SVITTASGLKYEDLTEGTGAEAQAGQTVSVHYTGWLTDGQKFDSSKDRNDPFAFVLGGG
CEEECCCCCEECCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCEEEEEECC
MVIKGWDEGVQGMKVGGVRRLTIPPQLGYGVRGAGGVIPPNATLVFEVELLAV
EEEECCCCCCCCEEECCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]