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The map label for this gene is manC [H]

Identifier: 189352375

GI number: 189352375

Start: 428598

End: 430124

Strand: Reverse

Name: manC [H]

Synonym: BMULJ_03594

Alternate gene names: 189352375

Gene position: 430124-428598 (Counterclockwise)

Preceding gene: 189352386

Following gene: 189352366

Centisome position: 17.39

GC content: 67.85

Gene sequence:

>1527_bases
ATGAATGCCCCGACCGTGACGGCCGACACGCATGACGTCGCCGCTGCCGCCCCTGCCGTCGGCACGCGCGTCGCCGTGCA
GCCGGTGATCCTTGCCGGCGGTTCCGGCACGCGCCTGTGGCCGATGTCGCGCGAACACTATCCGAAGCAGCTGATCGGCC
TGCTCGGCGACCATTCGCTGCTGCAGTCCACCGCGCTGCGTCTCGACGGCCTGACGGCCGGCCATCCGCTCAACGACGAC
GTGCTGATCGTCTGCGGCGAAGATCATCGCTTCACGACCGCCGAACAATTGCGTCTGACCGGCAAGCGCGCGTCGATCCT
GCTCGAGCCGATCGGTCGCGACACCGCGCCCGCGCTGACGCTGGCCGCGCTGAAGATCGTCGCGAGCGGCGACGATGCGG
TGATGACCGTGATGCCGGCCGATCATGCGGTCGCCGATCTGCCGCGCTTTCACGCGGCCGTCGCGGCCGGTGTGCACTGC
GCGGCGCAAGGCCGCATCGCGACGATGGGCATCGTGCCCGACCGCGCGGAGACGGGCTACGGCTACATCCGCGTCGGCGC
GCCGCTCGGCGATGCGGGCACGGGCACCCTCGACGTGCGCCGCCTCGACCGCTTCGTCGAGAAGCCGCATCTCGAACTCG
CGCAGCAGTACGTCGCGTCCGGCGAATATTGGTGGAACAGCGGGATCTTCATCGTGCGCGCGTCGGTCTGGCTGAATGCG
ATCCGCGAACTCGAGCCCGCGATCTATGCGGCCTGCGAGCAGGCGATCGCACAGGGTCGCGACGACGGCGACTTCTTCCG
CGTCGATCGCGACGCGTTCGCCGCGTCGCCGTCGAACTCGATCGACTACGCCGTGATGGAGCCGCTCGCGAACCGGCCGT
CCCTCTGCGAAAGCGTCGTCGTGCCGCTCGATGCGGGCTGGTCGGACGTCGGGTCGTGGGATGCAATCTGGCAGATCCTG
CCGAAGGACGATGCGGACAACGTCGGCCGCGGCCACGTGCTGTTCGAGAATGCCGACTCGACGTTCGCGCATGCGGAAAG
CCGGCTCGTCGCGTGCGTCGGCACGCACAATCTCGTCGTCGTCGAAACGCCCGACGCCGTGCTCGTCGCCGACAAGTCGC
GCGTGCAGGACGTGAAGAAAATCGTCGGGCGCATCAAGGCCGAACACGGCGCGGAAGCGACCGACCACCGCAAGGTGCAT
CGTCCGTGGGGCCATTACGATTCGGTCGACATGGGCGAGCGCTTCCAGGTCAAGCGCATCGTCGTGAAGCCCGGCGCGCG
GCTGTCGCTGCAGATGCATCATCATCGCGCCGAGCACTGGATCGTCGTGCGCGGCACCGCGCGCATCACGCGCGGCGACG
AGACCTTCCTGCTGTCGGAAAACGAATCGACGTATATCCCGCTCGGCGTCTCGCATCGCCTCGAGAATCCCGGCAAGATG
CCGCTCGAGCTGATCGAGGTGCAGTCGGGCGCGTACCTCGGCGAAGACGACATCGTGCGCTTCGACGATACGTACGGCCG
TCAGTAA

Upstream 100 bases:

>100_bases
TCAATGAAACGGCAATAATCGACAAAGGCCGCCGATTTTATTGTCGATTTACTTCGTGCTACAACGAAAGGCACTGACTT
CAATCGAGGAGAGTGCCATC

Downstream 100 bases:

>100_bases
CGCGCAAAGAAACGGGGCGCCGCATCGCGGCGCCCCGGCATCGAACCTCCGATCGTCGAACGCGCGCGGACATTGCCCGC
GCGTGTCGCGTGCGCGCCGT

Product: mannose-1-phosphate guanylyltransferase

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MNAPTVTADTHDVAAAAPAVGTRVAVQPVILAGGSGTRLWPMSREHYPKQLIGLLGDHSLLQSTALRLDGLTAGHPLNDD
VLIVCGEDHRFTTAEQLRLTGKRASILLEPIGRDTAPALTLAALKIVASGDDAVMTVMPADHAVADLPRFHAAVAAGVHC
AAQGRIATMGIVPDRAETGYGYIRVGAPLGDAGTGTLDVRRLDRFVEKPHLELAQQYVASGEYWWNSGIFIVRASVWLNA
IRELEPAIYAACEQAIAQGRDDGDFFRVDRDAFAASPSNSIDYAVMEPLANRPSLCESVVVPLDAGWSDVGSWDAIWQIL
PKDDADNVGRGHVLFENADSTFAHAESRLVACVGTHNLVVVETPDAVLVADKSRVQDVKKIVGRIKAEHGAEATDHRKVH
RPWGHYDSVDMGERFQVKRIVVKPGARLSLQMHHHRAEHWIVVRGTARITRGDETFLLSENESTYIPLGVSHRLENPGKM
PLELIEVQSGAYLGEDDIVRFDDTYGRQ

Sequences:

>Translated_508_residues
MNAPTVTADTHDVAAAAPAVGTRVAVQPVILAGGSGTRLWPMSREHYPKQLIGLLGDHSLLQSTALRLDGLTAGHPLNDD
VLIVCGEDHRFTTAEQLRLTGKRASILLEPIGRDTAPALTLAALKIVASGDDAVMTVMPADHAVADLPRFHAAVAAGVHC
AAQGRIATMGIVPDRAETGYGYIRVGAPLGDAGTGTLDVRRLDRFVEKPHLELAQQYVASGEYWWNSGIFIVRASVWLNA
IRELEPAIYAACEQAIAQGRDDGDFFRVDRDAFAASPSNSIDYAVMEPLANRPSLCESVVVPLDAGWSDVGSWDAIWQIL
PKDDADNVGRGHVLFENADSTFAHAESRLVACVGTHNLVVVETPDAVLVADKSRVQDVKKIVGRIKAEHGAEATDHRKVH
RPWGHYDSVDMGERFQVKRIVVKPGARLSLQMHHHRAEHWIVVRGTARITRGDETFLLSENESTYIPLGVSHRLENPGKM
PLELIEVQSGAYLGEDDIVRFDDTYGRQ
>Mature_508_residues
MNAPTVTADTHDVAAAAPAVGTRVAVQPVILAGGSGTRLWPMSREHYPKQLIGLLGDHSLLQSTALRLDGLTAGHPLNDD
VLIVCGEDHRFTTAEQLRLTGKRASILLEPIGRDTAPALTLAALKIVASGDDAVMTVMPADHAVADLPRFHAAVAAGVHC
AAQGRIATMGIVPDRAETGYGYIRVGAPLGDAGTGTLDVRRLDRFVEKPHLELAQQYVASGEYWWNSGIFIVRASVWLNA
IRELEPAIYAACEQAIAQGRDDGDFFRVDRDAFAASPSNSIDYAVMEPLANRPSLCESVVVPLDAGWSDVGSWDAIWQIL
PKDDADNVGRGHVLFENADSTFAHAESRLVACVGTHNLVVVETPDAVLVADKSRVQDVKKIVGRIKAEHGAEATDHRKVH
RPWGHYDSVDMGERFQVKRIVVKPGARLSLQMHHHRAEHWIVVRGTARITRGDETFLLSENESTYIPLGVSHRLENPGKM
PLELIEVQSGAYLGEDDIVRFDDTYGRQ

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=483, Percent_Identity=53.416149068323, Blast_Score=486, Evalue=1e-138,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 55246; Mature: 55246

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPTVTADTHDVAAAAPAVGTRVAVQPVILAGGSGTRLWPMSREHYPKQLIGLLGDHSL
CCCCEECCCCCHHHHHCCCCCCEEEEEEEEEECCCCCEECCCCHHCCHHHHHHHHCCHHH
LQSTALRLDGLTAGHPLNDDVLIVCGEDHRFTTAEQLRLTGKRASILLEPIGRDTAPALT
HHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCHHHHEECCCCEEEEEECCCCCCCHHHH
LAALKIVASGDDAVMTVMPADHAVADLPRFHAAVAAGVHCAAQGRIATMGIVPDRAETGY
EEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHCCEEECCCCEEEEECCCCCCCCCC
GYIRVGAPLGDAGTGTLDVRRLDRFVEKPHLELAQQYVASGEYWWNSGIFIVRASVWLNA
EEEEECCCCCCCCCCEEHHHHHHHHHCCHHHHHHHHHHHCCCEEECCCEEEEEHHHHHHH
IRELEPAIYAACEQAIAQGRDDGDFFRVDRDAFAASPSNSIDYAVMEPLANRPSLCESVV
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHCCCCCCCCCHHHHHHCCCCCCHHHHEE
VPLDAGWSDVGSWDAIWQILPKDDADNVGRGHVLFENADSTFAHAESRLVACVGTHNLVV
EECCCCCCCCCCHHHHHEECCCCCCCCCCCCEEEEECCCCHHHHCCCCEEEEECCCCEEE
VETPDAVLVADKSRVQDVKKIVGRIKAEHGAEATDHRKVHRPWGHYDSVDMGERFQVKRI
EECCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEE
VVKPGARLSLQMHHHRAEHWIVVRGTARITRGDETFLLSENESTYIPLGVSHRLENPGKM
EECCCCEEEEEEECCCCCEEEEEECCEEEECCCCEEEEECCCCEEEEECHHHCCCCCCCC
PLELIEVQSGAYLGEDDIVRFDDTYGRQ
CEEEEEECCCCEECCCCEEEECCCCCCC
>Mature Secondary Structure
MNAPTVTADTHDVAAAAPAVGTRVAVQPVILAGGSGTRLWPMSREHYPKQLIGLLGDHSL
CCCCEECCCCCHHHHHCCCCCCEEEEEEEEEECCCCCEECCCCHHCCHHHHHHHHCCHHH
LQSTALRLDGLTAGHPLNDDVLIVCGEDHRFTTAEQLRLTGKRASILLEPIGRDTAPALT
HHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCHHHHEECCCCEEEEEECCCCCCCHHHH
LAALKIVASGDDAVMTVMPADHAVADLPRFHAAVAAGVHCAAQGRIATMGIVPDRAETGY
EEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHCCEEECCCCEEEEECCCCCCCCCC
GYIRVGAPLGDAGTGTLDVRRLDRFVEKPHLELAQQYVASGEYWWNSGIFIVRASVWLNA
EEEEECCCCCCCCCCEEHHHHHHHHHCCHHHHHHHHHHHCCCEEECCCEEEEEHHHHHHH
IRELEPAIYAACEQAIAQGRDDGDFFRVDRDAFAASPSNSIDYAVMEPLANRPSLCESVV
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHCCCCCCCCCHHHHHHCCCCCCHHHHEE
VPLDAGWSDVGSWDAIWQILPKDDADNVGRGHVLFENADSTFAHAESRLVACVGTHNLVV
EECCCCCCCCCCHHHHHEECCCCCCCCCCCCEEEEECCCCHHHHCCCCEEEEECCCCEEE
VETPDAVLVADKSRVQDVKKIVGRIKAEHGAEATDHRKVHRPWGHYDSVDMGERFQVKRI
EECCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEE
VVKPGARLSLQMHHHRAEHWIVVRGTARITRGDETFLLSENESTYIPLGVSHRLENPGKM
EECCCCEEEEEEECCCCCEEEEEECCEEEECCCCEEEEECCCCEEEEECHHHCCCCCCCC
PLELIEVQSGAYLGEDDIVRFDDTYGRQ
CEEEEEECCCCEECCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]