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The map label for this gene is nahR [H]

Identifier: 189352331

GI number: 189352331

Start: 381759

End: 382652

Strand: Reverse

Name: nahR [H]

Synonym: BMULJ_03550

Alternate gene names: 189352331

Gene position: 382652-381759 (Counterclockwise)

Preceding gene: 189352333

Following gene: 189352330

Centisome position: 15.47

GC content: 70.02

Gene sequence:

>894_bases
ATGACTAATTTGCGGCGACTCGACCTGAACCTGCTCGTGACGCTCGACGTGCTGCTCGCCGAACTCAACGTGACGCGCGC
GGCCGAGAAGCTCAACCTTTCGCAGCCGTCGGTCAGCGTGCATCTGCAGAAGCTGCGCGATACGTTCGGCGATCCGCTGC
TGCTGCCGGGGCCGCGCGGCATGCGGCCGACCGCGCGCGCCGAAGCGCTGCGCGAGCCGCTGCGCGACGCGCTCGAGGCG
GTCGAACGCGCGGTGCTGCCCGCGACACCGTTCGATCCGTCGACCGCGACGCATACGTGGCGCGTGGCCGCGACCGACTA
CGGCGAATCGACGATCGTGCTGCCCGCGCTGCATGCGCTGCGCACGGCCGCGCCCGGCACGCGGCTCGCGATCGTCGAGC
TCGTGCCGCCGCGCATCGAGCAGGCCGCCGCGCGCAACGACATCGATCTCGCCTTCCATACGACCGAAGGATCGCCGCCC
GGCATGCGCCGGCTGCCGCTGTTCGTCGAGCGCTACGTGCTCGTCGGCCGCGCCGGTCATCCGAAACTGAAACGTCGCCC
GACGCTCGCGCAGTTCAATGCGCTCGAGCATGTGATCGTGTCGCCGGACGGCGGCGGCTTCTTCGGCGTGACCGACGAGG
CGCTCGCGAAGGTCGGCGCGACGCGGCGCGTCGTGCTGTCCGTTCCGCATTTCCTGTTCGTGATGTCGGTGCTCGCGAGC
AGCGATCTCGTCGCGATGCTGCCCGAGCGGCTCGTGCGCGATACGCCTGCGTTGCGCGTCGTCGACGCGCCGATCGACGT
GCCCGGCTACGAAATGTCGATGCTGTGGCACGAGCGCGTGCATCGCGATCCGGCGCATCGGTGGCTGCGCGAAACGATCG
CCGCCGCGGTCTAG

Upstream 100 bases:

>100_bases
TCAGCACGTTCATGTTCGGTCCTCCGTCGGTTGAATGGACTGCAGGATGCCGATCGCGCAGGTATATTGGAAATGAATTT
CCGATATTCCAGGTATAGCG

Downstream 100 bases:

>100_bases
CGAACGGAATCGCGTCCGGGGCTTGAAACGGCGCGAAACACTGTATATATTTACAGTGCTTTTGCACCATTTGACCCGAA
TTCCGTCATCCCGCGACGGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MTNLRRLDLNLLVTLDVLLAELNVTRAAEKLNLSQPSVSVHLQKLRDTFGDPLLLPGPRGMRPTARAEALREPLRDALEA
VERAVLPATPFDPSTATHTWRVAATDYGESTIVLPALHALRTAAPGTRLAIVELVPPRIEQAAARNDIDLAFHTTEGSPP
GMRRLPLFVERYVLVGRAGHPKLKRRPTLAQFNALEHVIVSPDGGGFFGVTDEALAKVGATRRVVLSVPHFLFVMSVLAS
SDLVAMLPERLVRDTPALRVVDAPIDVPGYEMSMLWHERVHRDPAHRWLRETIAAAV

Sequences:

>Translated_297_residues
MTNLRRLDLNLLVTLDVLLAELNVTRAAEKLNLSQPSVSVHLQKLRDTFGDPLLLPGPRGMRPTARAEALREPLRDALEA
VERAVLPATPFDPSTATHTWRVAATDYGESTIVLPALHALRTAAPGTRLAIVELVPPRIEQAAARNDIDLAFHTTEGSPP
GMRRLPLFVERYVLVGRAGHPKLKRRPTLAQFNALEHVIVSPDGGGFFGVTDEALAKVGATRRVVLSVPHFLFVMSVLAS
SDLVAMLPERLVRDTPALRVVDAPIDVPGYEMSMLWHERVHRDPAHRWLRETIAAAV
>Mature_296_residues
TNLRRLDLNLLVTLDVLLAELNVTRAAEKLNLSQPSVSVHLQKLRDTFGDPLLLPGPRGMRPTARAEALREPLRDALEAV
ERAVLPATPFDPSTATHTWRVAATDYGESTIVLPALHALRTAAPGTRLAIVELVPPRIEQAAARNDIDLAFHTTEGSPPG
MRRLPLFVERYVLVGRAGHPKLKRRPTLAQFNALEHVIVSPDGGGFFGVTDEALAKVGATRRVVLSVPHFLFVMSVLASS
DLVAMLPERLVRDTPALRVVDAPIDVPGYEMSMLWHERVHRDPAHRWLRETIAAAV

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=302, Percent_Identity=27.8145695364238, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI87081766, Length=254, Percent_Identity=27.1653543307087, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1790147, Length=303, Percent_Identity=25.4125412541254, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788887, Length=261, Percent_Identity=26.4367816091954, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32669; Mature: 32538

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLRRLDLNLLVTLDVLLAELNVTRAAEKLNLSQPSVSVHLQKLRDTFGDPLLLPGPRG
CCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEECCCCCC
MRPTARAEALREPLRDALEAVERAVLPATPFDPSTATHTWRVAATDYGESTIVLPALHAL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCEEHHHHHHHH
RTAAPGTRLAIVELVPPRIEQAAARNDIDLAFHTTEGSPPGMRRLPLFVERYVLVGRAGH
HHCCCCCEEEEEEECCCHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCC
PKLKRRPTLAQFNALEHVIVSPDGGGFFGVTDEALAKVGATRRVVLSVPHFLFVMSVLAS
CCHHCCCCHHHHHCCCEEEECCCCCCEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
SDLVAMLPERLVRDTPALRVVDAPIDVPGYEMSMLWHERVHRDPAHRWLRETIAAAV
CCHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNLRRLDLNLLVTLDVLLAELNVTRAAEKLNLSQPSVSVHLQKLRDTFGDPLLLPGPRG
CCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEECCCCCC
MRPTARAEALREPLRDALEAVERAVLPATPFDPSTATHTWRVAATDYGESTIVLPALHAL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCEEHHHHHHHH
RTAAPGTRLAIVELVPPRIEQAAARNDIDLAFHTTEGSPPGMRRLPLFVERYVLVGRAGH
HHCCCCCEEEEEEECCCHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCC
PKLKRRPTLAQFNALEHVIVSPDGGGFFGVTDEALAKVGATRRVVLSVPHFLFVMSVLAS
CCHHCCCCHHHHHCCCEEEECCCCCCEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
SDLVAMLPERLVRDTPALRVVDAPIDVPGYEMSMLWHERVHRDPAHRWLRETIAAAV
CCHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]