BacMap

Definition	Burkholderia multivorans ATCC 17616 chromosome 2, complete genome.
Accession	NC_010805
Length	2,473,162

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The map label for this gene is ephD [H]

Identifier: 189352256

GI number: 189352256

Start: 300567

End: 301469

Strand: Reverse

Name: ephD [H]

Synonym: BMULJ_03474

Alternate gene names: 189352256

Gene position: 301469-300567 (Counterclockwise)

Preceding gene: 189352258

Following gene: 189352255

Centisome position: 12.19

GC content: 71.98

Gene sequence:

>903_bases
ATGAAGGGTTTTTCCGGCAAGGTCGCCGCAATCACGGGCGCCGGTTCGGGGATGGGCCGCAGCCTGGCGGTCGAGCTCGC
GCGGCGCGGCTGCGAGGTGGCGCTCGCCGACGTCAACGACGTCGGGCTCGCCGGCACGGCGGCCGCGTGCGCGCAGCACG
GCGTGCGGACGAGCACGCGGCGCGTCGACGTCGCCGACCGCGACGCCGTGTTCGCGTGGGCCGATTTCGTCCGCGCCGAA
CACGGCAAGGTGAACCTGATCTTCAACAACGCGGGCGTGTCGCTGGCCGCGAGCGCCGAGACGGCGAGCCTCGCCGATCT
CGAATGGATCGTCGGCATCAACTTCTGGGGCGTCGTGCACGGCACGCAGGCGTTCCTCCCGCATCTGCGCGCGTCCGGCG
ACGGGCACGTGGTCAATACGTCGAGCCTGTTCGGGCTCATCGCGATGCCGACGCAAAGCGCGTACAACGCGACGAAGTTC
GCCGTGCGCGGCTTCACCGAAGCGCTGCGGATGGAGCTCGAACTCGACGGCGCGCCCGTCAGCGCGACCTGCGTGCATCC
GGGTGGCGTCGCGACGAACATCGTCGATGCGAGCCGCGTCGACACCAGCATTCGCGCGCTCACCGGCCAGGACGAAGCGA
CCCATCGCCGTCAGGCGAATCGCCTGATCAATGCGACGACCGCCGACGACGCCGCCCGCCAGATCCTCGCCGGCGTCGAG
CACAACGCGCGCCGCGTGCTGGTCGGCGCCGATGCGCGCCGCCTCGACACGCTCGCGCGCGTGCTCGGCGCCGGCTATCA
GCGGCTCGTGCTGCGCCACGTGCGCCGCGCCCGCGCGCGCAATCTCGCACGCACGGCCACGCCGGCCGCGCCCGCCTCGA
CCGCGATCAAGGACACCGCATGA

Upstream 100 bases:

>100_bases
CGCTATTTGACATCAGGACACCCGAAAACTAAAGTGGTGACGACCAACACCACAATAGACACGCCGCCGGCACGACGGTA
GCGGAACGGGAGGACGACGG

Downstream 100 bases:

>100_bases
CCTCGACGACGACCGACCGGCGCGCCGCGCCGCCCGCCTGCGGCGACAGCCGCGACCTCGACGTGCTGATCGTCGGTGCC
GGCCTGTCCGGCATCGGCGC

Product: acetoin dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MKGFSGKVAAITGAGSGMGRSLAVELARRGCEVALADVNDVGLAGTAAACAQHGVRTSTRRVDVADRDAVFAWADFVRAE
HGKVNLIFNNAGVSLAASAETASLADLEWIVGINFWGVVHGTQAFLPHLRASGDGHVVNTSSLFGLIAMPTQSAYNATKF
AVRGFTEALRMELELDGAPVSATCVHPGGVATNIVDASRVDTSIRALTGQDEATHRRQANRLINATTADDAARQILAGVE
HNARRVLVGADARRLDTLARVLGAGYQRLVLRHVRRARARNLARTATPAAPASTAIKDTA

Sequences:

>Translated_300_residues
MKGFSGKVAAITGAGSGMGRSLAVELARRGCEVALADVNDVGLAGTAAACAQHGVRTSTRRVDVADRDAVFAWADFVRAE
HGKVNLIFNNAGVSLAASAETASLADLEWIVGINFWGVVHGTQAFLPHLRASGDGHVVNTSSLFGLIAMPTQSAYNATKF
AVRGFTEALRMELELDGAPVSATCVHPGGVATNIVDASRVDTSIRALTGQDEATHRRQANRLINATTADDAARQILAGVE
HNARRVLVGADARRLDTLARVLGAGYQRLVLRHVRRARARNLARTATPAAPASTAIKDTA
>Mature_300_residues
MKGFSGKVAAITGAGSGMGRSLAVELARRGCEVALADVNDVGLAGTAAACAQHGVRTSTRRVDVADRDAVFAWADFVRAE
HGKVNLIFNNAGVSLAASAETASLADLEWIVGINFWGVVHGTQAFLPHLRASGDGHVVNTSSLFGLIAMPTQSAYNATKF
AVRGFTEALRMELELDGAPVSATCVHPGGVATNIVDASRVDTSIRALTGQDEATHRRQANRLINATTADDAARQILAGVE
HNARRVLVGADARRLDTLARVLGAGYQRLVLRHVRRARARNLARTATPAAPASTAIKDTA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI142976729, Length=262, Percent_Identity=29.7709923664122, Blast_Score=114, Evalue=9e-26,
Organism=Homo sapiens, GI210032110, Length=262, Percent_Identity=26.7175572519084, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI7706318, Length=221, Percent_Identity=28.9592760180996, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI40807363, Length=197, Percent_Identity=31.9796954314721, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI25282469, Length=238, Percent_Identity=31.0924369747899, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI7657478, Length=242, Percent_Identity=30.1652892561983, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI310128830, Length=249, Percent_Identity=29.718875502008, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI310115468, Length=249, Percent_Identity=29.718875502008, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI44680136, Length=188, Percent_Identity=35.6382978723404, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI44680133, Length=188, Percent_Identity=35.6382978723404, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI17738292, Length=188, Percent_Identity=35.6382978723404, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI20149619, Length=279, Percent_Identity=27.2401433691756, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI40548397, Length=221, Percent_Identity=29.4117647058824, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI214010158, Length=221, Percent_Identity=29.4117647058824, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI214010156, Length=221, Percent_Identity=29.4117647058824, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI22758144, Length=221, Percent_Identity=29.4117647058824, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4503817, Length=257, Percent_Identity=25.6809338521401, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI109715829, Length=200, Percent_Identity=27, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI22507405, Length=251, Percent_Identity=28.2868525896414, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI223718074, Length=219, Percent_Identity=30.1369863013699, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=33, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4504503, Length=257, Percent_Identity=27.6264591439689, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI166795268, Length=209, Percent_Identity=32.0574162679426, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI150247226, Length=202, Percent_Identity=32.1782178217822, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI4557649, Length=280, Percent_Identity=27.8571428571429, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI224922801, Length=167, Percent_Identity=32.9341317365269, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI186928839, Length=287, Percent_Identity=30.6620209059233, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI31543615, Length=185, Percent_Identity=32.4324324324324, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI32455239, Length=243, Percent_Identity=29.2181069958848, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI5031765, Length=243, Percent_Identity=29.2181069958848, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI87082100, Length=198, Percent_Identity=33.8383838383838, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1786701, Length=198, Percent_Identity=34.8484848484849, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1789208, Length=199, Percent_Identity=29.1457286432161, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787335, Length=197, Percent_Identity=27.9187817258883, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787905, Length=140, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787820, Length=192, Percent_Identity=28.125, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788459, Length=199, Percent_Identity=28.1407035175879, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI87082160, Length=202, Percent_Identity=28.2178217821782, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17567345, Length=197, Percent_Identity=31.9796954314721, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI193203117, Length=192, Percent_Identity=30.7291666666667, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI193203115, Length=195, Percent_Identity=30.2564102564103, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71997402, Length=172, Percent_Identity=33.7209302325581, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=212, Percent_Identity=30.6603773584906, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17570069, Length=172, Percent_Identity=33.1395348837209, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=213, Percent_Identity=30.0469483568075, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=220, Percent_Identity=30, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=172, Percent_Identity=28.4883720930233, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=200, Percent_Identity=32, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=203, Percent_Identity=32.512315270936, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=207, Percent_Identity=29.951690821256, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=199, Percent_Identity=29.6482412060301, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=197, Percent_Identity=29.9492385786802, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=200, Percent_Identity=28, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=226, Percent_Identity=28.3185840707965, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=203, Percent_Identity=31.5270935960591, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=195, Percent_Identity=28.7179487179487, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=203, Percent_Identity=30.0492610837438, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=206, Percent_Identity=30.5825242718447, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17544670, Length=208, Percent_Identity=27.8846153846154, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=239, Percent_Identity=28.0334728033473, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323882, Length=195, Percent_Identity=28.2051282051282, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322861, Length=182, Percent_Identity=29.6703296703297, Blast_Score=63, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6320089, Length=271, Percent_Identity=24.7232472324723, Blast_Score=62, Evalue=9e-11,
Organism=Drosophila melanogaster, GI21355631, Length=175, Percent_Identity=35.4285714285714, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24649181, Length=283, Percent_Identity=26.8551236749117, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI281364892, Length=173, Percent_Identity=32.9479768786127, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI21358495, Length=256, Percent_Identity=30.859375, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24644339, Length=195, Percent_Identity=33.8461538461538, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24640492, Length=201, Percent_Identity=30.8457711442786, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI28571526, Length=218, Percent_Identity=31.651376146789, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI221510726, Length=303, Percent_Identity=28.0528052805281, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24581726, Length=201, Percent_Identity=29.8507462686567, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI281364494, Length=212, Percent_Identity=30.6603773584906, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI23397609, Length=192, Percent_Identity=32.2916666666667, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21356301, Length=187, Percent_Identity=28.3422459893048, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640442, Length=197, Percent_Identity=31.4720812182741, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357041, Length=195, Percent_Identity=30.7692307692308, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641388, Length=208, Percent_Identity=32.2115384615385, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571387, Length=206, Percent_Identity=28.6407766990291, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24665243, Length=259, Percent_Identity=26.2548262548263, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI116007236, Length=204, Percent_Identity=31.3725490196078, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221331218, Length=259, Percent_Identity=26.2548262548263, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24648693, Length=209, Percent_Identity=30.622009569378, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21355889, Length=209, Percent_Identity=30.622009569378, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24639444, Length=195, Percent_Identity=29.7435897435897, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI18859837, Length=178, Percent_Identity=29.2134831460674, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24665247, Length=260, Percent_Identity=26.1538461538462, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI221331216, Length=260, Percent_Identity=26.1538461538462, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24641232, Length=224, Percent_Identity=29.0178571428571, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31450; Mature: 31450

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGFSGKVAAITGAGSGMGRSLAVELARRGCEVALADVNDVGLAGTAAACAQHGVRTSTR
CCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHCCCCCCCC
RVDVADRDAVFAWADFVRAEHGKVNLIFNNAGVSLAASAETASLADLEWIVGINFWGVVH
EECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCCHHCEEEEEEEEEEEECC
GTQAFLPHLRASGDGHVVNTSSLFGLIAMPTQSAYNATKFAVRGFTEALRMELELDGAPV
CHHHHHHHHHCCCCCCEEEHHHHEEEEECCCCCCCCHHHHHHHHHHHHHEEEEEECCCCE
SATCVHPGGVATNIVDASRVDTSIRALTGQDEATHRRQANRLINATTADDAARQILAGVE
EEEEECCCCCCHHCCCHHHHCCHHHEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
HNARRVLVGADARRLDTLARVLGAGYQRLVLRHVRRARARNLARTATPAAPASTAIKDTA
CCCCEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKGFSGKVAAITGAGSGMGRSLAVELARRGCEVALADVNDVGLAGTAAACAQHGVRTSTR
CCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHCCCCCCCC
RVDVADRDAVFAWADFVRAEHGKVNLIFNNAGVSLAASAETASLADLEWIVGINFWGVVH
EECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCCHHCEEEEEEEEEEEECC
GTQAFLPHLRASGDGHVVNTSSLFGLIAMPTQSAYNATKFAVRGFTEALRMELELDGAPV
CHHHHHHHHHCCCCCCEEEHHHHEEEEECCCCCCCCHHHHHHHHHHHHHEEEEEECCCCE
SATCVHPGGVATNIVDASRVDTSIRALTGQDEATHRRQANRLINATTADDAARQILAGVE
EEEEECCCCCCHHCCCHHHHCCHHHEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
HNARRVLVGADARRLDTLARVLGAGYQRLVLRHVRRARARNLARTATPAAPASTAIKDTA
CCCCEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]