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The map label for this gene is abgR [H]

Identifier: 189352066

GI number: 189352066

Start: 85364

End: 86299

Strand: Reverse

Name: abgR [H]

Synonym: BMULJ_03283

Alternate gene names: 189352066

Gene position: 86299-85364 (Counterclockwise)

Preceding gene: 189352070

Following gene: 189352065

Centisome position: 3.49

GC content: 71.47

Gene sequence:

>936_bases
ATGAAACTCAAGCAGCTCAATGCATTCCTCGCCGTCGCCGAGCACCGCACGATCCGCGGCGCCGCCCGCGCGCTCGGCGT
CACGCAGCCGGCCGTCAGCGGTATCGTGCGCGAGCTCGAAGGCGAGCTCGGCGTGCCGCTCGTGATGCGCAGCGTCAAGG
GCGTCGCCTTGACCGATTACGGCAGCGCGTTCGCGATCCGCGCGCGGCGCATCGTCGAGGAGATCCAGCGCACGCGCGAC
GAAATCGAGCAGTTGCGACTCGGCACGACCGGGTCGGTGTCGATCGCGGTCAGCCCGACCGTCGCGCTGACGATCCTGCC
GCACGCCTTCGATGCGTTCACGCGCGCGCTGCCCGGCGCGACGGTCAATATCGACGACGCGCTGACTGCGACCGATCTCG
CCCGACTGCGCGACGGTTCACTCGATTTCATCGTCACGCATCAGCTGTCGGACGCGCTGCCGGACGCCGACGAATTCGCG
AGCATTCCGCTGTTCCGCACCGCGTTCGTCGTGGTCGCCCGCAGCCGGCATCGGCTGGCCCGCGCGCGGTCGCTGCGCGA
GCTCGGCGACGCGCGCTGGTGCGTGCCGCGCTACGGGGACGGCGGCGACGATCTGATCCGGTCGATCTTCGTTCCGCGCG
GGATCGAGATGCCGAAGCGGATCGTGCACTGCCCGTCGTTCGCGGCGACGCTCGGGCTCGTGTCGCGGACGGACGCGCTC
GGCGTCTTCGCGCGGCCGCTCGCCGACGTCGAGCGCGGCTCGCGCCGGCTCGTCGTGCTCGATCTCGTCGAGCCGCTGCC
GGCGCTGACGGTCGCGATCGTGATGCGGCGGCACGCGCTGCTGACGCCGGCCGCGCTGCGCTTGATCGACTGTTTGAAGG
CGGCCGCGGCCGAGGTGTCGGGTGGCGAGGGCGGCGGCGACAGCGACGGCGTGTGA

Upstream 100 bases:

>100_bases
AGTCGCTCCTGAAAAGCCCCGAGCATATACACTCGATCCGATAAGGAAAATCCAAGAGTTTCTTGCGCACGATAACTTCT
TCTTGTCACCCGTCACCCCG

Downstream 100 bases:

>100_bases
TCTGCGTGGGCGGAGGGAGGTGGGCACGGGCGCCGGACACCACGCATGGACCACGCGGCGCACGGCGCACATGGGAAACG
GAGGCACACACGGGCATCCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKLKQLNAFLAVAEHRTIRGAARALGVTQPAVSGIVRELEGELGVPLVMRSVKGVALTDYGSAFAIRARRIVEEIQRTRD
EIEQLRLGTTGSVSIAVSPTVALTILPHAFDAFTRALPGATVNIDDALTATDLARLRDGSLDFIVTHQLSDALPDADEFA
SIPLFRTAFVVVARSRHRLARARSLRELGDARWCVPRYGDGGDDLIRSIFVPRGIEMPKRIVHCPSFAATLGLVSRTDAL
GVFARPLADVERGSRRLVVLDLVEPLPALTVAIVMRRHALLTPAALRLIDCLKAAAAEVSGGEGGGDSDGV

Sequences:

>Translated_311_residues
MKLKQLNAFLAVAEHRTIRGAARALGVTQPAVSGIVRELEGELGVPLVMRSVKGVALTDYGSAFAIRARRIVEEIQRTRD
EIEQLRLGTTGSVSIAVSPTVALTILPHAFDAFTRALPGATVNIDDALTATDLARLRDGSLDFIVTHQLSDALPDADEFA
SIPLFRTAFVVVARSRHRLARARSLRELGDARWCVPRYGDGGDDLIRSIFVPRGIEMPKRIVHCPSFAATLGLVSRTDAL
GVFARPLADVERGSRRLVVLDLVEPLPALTVAIVMRRHALLTPAALRLIDCLKAAAAEVSGGEGGGDSDGV
>Mature_311_residues
MKLKQLNAFLAVAEHRTIRGAARALGVTQPAVSGIVRELEGELGVPLVMRSVKGVALTDYGSAFAIRARRIVEEIQRTRD
EIEQLRLGTTGSVSIAVSPTVALTILPHAFDAFTRALPGATVNIDDALTATDLARLRDGSLDFIVTHQLSDALPDADEFA
SIPLFRTAFVVVARSRHRLARARSLRELGDARWCVPRYGDGGDDLIRSIFVPRGIEMPKRIVHCPSFAATLGLVSRTDAL
GVFARPLADVERGSRRLVVLDLVEPLPALTVAIVMRRHALLTPAALRLIDCLKAAAAEVSGGEGGGDSDGV

Specific function: Could be the regulator of the abg operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=290, Percent_Identity=30, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1789506, Length=296, Percent_Identity=28.0405405405405, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1790399, Length=206, Percent_Identity=29.126213592233, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI145693105, Length=296, Percent_Identity=27.3648648648649, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI157672245, Length=315, Percent_Identity=29.2063492063492, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788887, Length=190, Percent_Identity=30, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787128, Length=130, Percent_Identity=33.0769230769231, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789639, Length=144, Percent_Identity=29.8611111111111, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788748, Length=310, Percent_Identity=26.4516129032258, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI2367136, Length=263, Percent_Identity=26.9961977186312, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788481, Length=306, Percent_Identity=25.1633986928105, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081904, Length=179, Percent_Identity=27.9329608938547, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33347; Mature: 33347

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKQLNAFLAVAEHRTIRGAARALGVTQPAVSGIVRELEGELGVPLVMRSVKGVALTDY
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHCCCEEEECC
GSAFAIRARRIVEEIQRTRDEIEQLRLGTTGSVSIAVSPTVALTILPHAFDAFTRALPGA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEEHHHHHHHHHHHCCCC
TVNIDDALTATDLARLRDGSLDFIVTHQLSDALPDADEFASIPLFRTAFVVVARSRHRLA
EEECCCHHHHHHHHHHCCCCEEEEEEECHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHH
RARSLRELGDARWCVPRYGDGGDDLIRSIFVPRGIEMPKRIVHCPSFAATLGLVSRTDAL
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHH
GVFARPLADVERGSRRLVVLDLVEPLPALTVAIVMRRHALLTPAALRLIDCLKAAAAEVS
HHHHHHHHHHHCCCCEEEEEEHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
GGEGGGDSDGV
CCCCCCCCCCC
>Mature Secondary Structure
MKLKQLNAFLAVAEHRTIRGAARALGVTQPAVSGIVRELEGELGVPLVMRSVKGVALTDY
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHCCCEEEECC
GSAFAIRARRIVEEIQRTRDEIEQLRLGTTGSVSIAVSPTVALTILPHAFDAFTRALPGA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEEHHHHHHHHHHHCCCC
TVNIDDALTATDLARLRDGSLDFIVTHQLSDALPDADEFASIPLFRTAFVVVARSRHRLA
EEECCCHHHHHHHHHHCCCCEEEEEEECHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHH
RARSLRELGDARWCVPRYGDGGDDLIRSIFVPRGIEMPKRIVHCPSFAATLGLVSRTDAL
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHH
GVFARPLADVERGSRRLVVLDLVEPLPALTVAIVMRRHALLTPAALRLIDCLKAAAAEVS
HHHHHHHHHHHCCCCEEEEEEHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
GGEGGGDSDGV
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9829935 [H]