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The map label for this gene is ndh [H]

Identifier: 189352055

GI number: 189352055

Start: 73869

End: 75227

Strand: Reverse

Name: ndh [H]

Synonym: BMULJ_03272

Alternate gene names: 189352055

Gene position: 75227-73869 (Counterclockwise)

Preceding gene: 189352057

Following gene: 189352054

Centisome position: 3.04

GC content: 69.9

Gene sequence:

>1359_bases
ATGGACAACACCACGCCTCTCGTTGCCGCGCCCGCCGCACCGCGTGTGCCGCGCATCGTGATCGTCGGCGGCGGCGCCGG
CGGCCTGCATCTCGCGACGCGCCTCGGCGACACGATCGGCCGCCGCGGCCACACCGAAGTCGTACTCGTCGACCGCTATC
CGACGCACTTCTGGAAGCCGCTGCTGCACGAAGCGGCATCGGGCCATCGCGATCCGGCGTCGCACACGATCGAATACGCG
GCGCAGGCGAAGCGGCACGGCTTCCGCTTCGTGCAGGGCGCGCTGCAACGCGTCGATCGCGCGGCGCGCATCGCGACGAT
CGGCGCGGTGCACGACGCGGACGGCACCGAAATCCTGCCGGCGCGCACGCTCGCCTACGACGATCTGGTGCTCGCGGTCG
GCAGCGTGACGAACTTCTTCGGCGTGCCGGGCGCGGCGCGCCATGCGCTGCCGCTCGAAAACCTCGATCAGGCCGAGGAC
TTCCGCCGCAAGTTTCTCGCGGCCTGCACGAAGGCGAACCATCGCGCCGAGCAGCAGCCGGCGCAGCCGGCCGCACCGGT
CAGCATCAGCGTGATCGGCGCGGGCGCGACGGGTGTCGAACTCGCGGCCGCGCTGCGTCACGCGGTCCAGCAGCTGACGA
CGTATCGGTTCAAGGCGCTCGACGGCGCGCGCGACGTACGGATCCGTCTGATCGAAGGCGCGCCGCGCATTCTGCCGGCG
CTCGATGCACGGCTGTCGGACAAGATGCACGCGCAGCTGCGCGCGCTGAACGTCGAGGTGCTGACCGATACGCGCGTCGC
CGAAGTCGGCGCCGATGCGGTGACGATCGCGAGCGGCGAACGGCTCGCGAGCGACATCACGATCTGGGCCGCCGGCGTCG
CGGGGCCGGCGATCCTGCGCGAACTCGACGGCATCGCACTCAACCGGTCGAATCAGGTGATCGTCACCGATACGCTGCAG
ACACCCGACGATCCGCACGTGCACGCGTTCGGCGACTGCGCCGCGTGTCCGTCGAACGGCGCGAGCGGCTGTCTGCCGCC
GCGCGCGCAGGTCGCGCATCAGCAGGCCGTCTATCTGAGCCAGGCGTTCGCGCGCCGCATCGCCGGCAAGCCGGTCGCGG
GATTCACGTTCCGCGACGCCGGCACGGTCGTATCGCTCGGGCATGCAGGCGCCGTCTATCAGGCCGAACTCGGCGTGCGC
TCGCGTTCGCTGATCGTCGACGGGCTCGCCGCGATCGGGCTTTACAAGTTCCTGTATCGCAAGCACCTGTTCAGCGTGCA
CGGCATCAAGCGCGCACTGTTCCAGTCGCTGAGCCACTGGCTGCAAAGCCGCAATCAGCCGTCGATCAAGCTGCACTGA

Upstream 100 bases:

>100_bases
AGTCGCTTATAAACATTGAATTGTTCGATGGGTTGCCAAACTATATCGTCGGTTCCTGAGCAATGTCATCCCGATATTCG
TCATCAGCAGGAGCCCGAAC

Downstream 100 bases:

>100_bases
AGCACCGCCGTGCGCGATGCGAAAAAAGGCGGCGTACCGCGACTGTCGCACGGTACGCCGCCCTTTTTTTCGCATGGCGA
ATTCGCCAGCCCGTTGCCAT

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MDNTTPLVAAPAAPRVPRIVIVGGGAGGLHLATRLGDTIGRRGHTEVVLVDRYPTHFWKPLLHEAASGHRDPASHTIEYA
AQAKRHGFRFVQGALQRVDRAARIATIGAVHDADGTEILPARTLAYDDLVLAVGSVTNFFGVPGAARHALPLENLDQAED
FRRKFLAACTKANHRAEQQPAQPAAPVSISVIGAGATGVELAAALRHAVQQLTTYRFKALDGARDVRIRLIEGAPRILPA
LDARLSDKMHAQLRALNVEVLTDTRVAEVGADAVTIASGERLASDITIWAAGVAGPAILRELDGIALNRSNQVIVTDTLQ
TPDDPHVHAFGDCAACPSNGASGCLPPRAQVAHQQAVYLSQAFARRIAGKPVAGFTFRDAGTVVSLGHAGAVYQAELGVR
SRSLIVDGLAAIGLYKFLYRKHLFSVHGIKRALFQSLSHWLQSRNQPSIKLH

Sequences:

>Translated_452_residues
MDNTTPLVAAPAAPRVPRIVIVGGGAGGLHLATRLGDTIGRRGHTEVVLVDRYPTHFWKPLLHEAASGHRDPASHTIEYA
AQAKRHGFRFVQGALQRVDRAARIATIGAVHDADGTEILPARTLAYDDLVLAVGSVTNFFGVPGAARHALPLENLDQAED
FRRKFLAACTKANHRAEQQPAQPAAPVSISVIGAGATGVELAAALRHAVQQLTTYRFKALDGARDVRIRLIEGAPRILPA
LDARLSDKMHAQLRALNVEVLTDTRVAEVGADAVTIASGERLASDITIWAAGVAGPAILRELDGIALNRSNQVIVTDTLQ
TPDDPHVHAFGDCAACPSNGASGCLPPRAQVAHQQAVYLSQAFARRIAGKPVAGFTFRDAGTVVSLGHAGAVYQAELGVR
SRSLIVDGLAAIGLYKFLYRKHLFSVHGIKRALFQSLSHWLQSRNQPSIKLH
>Mature_452_residues
MDNTTPLVAAPAAPRVPRIVIVGGGAGGLHLATRLGDTIGRRGHTEVVLVDRYPTHFWKPLLHEAASGHRDPASHTIEYA
AQAKRHGFRFVQGALQRVDRAARIATIGAVHDADGTEILPARTLAYDDLVLAVGSVTNFFGVPGAARHALPLENLDQAED
FRRKFLAACTKANHRAEQQPAQPAAPVSISVIGAGATGVELAAALRHAVQQLTTYRFKALDGARDVRIRLIEGAPRILPA
LDARLSDKMHAQLRALNVEVLTDTRVAEVGADAVTIASGERLASDITIWAAGVAGPAILRELDGIALNRSNQVIVTDTLQ
TPDDPHVHAFGDCAACPSNGASGCLPPRAQVAHQQAVYLSQAFARRIAGKPVAGFTFRDAGTVVSLGHAGAVYQAELGVR
SRSLIVDGLAAIGLYKFLYRKHLFSVHGIKRALFQSLSHWLQSRNQPSIKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=451, Percent_Identity=38.8026607538803, Blast_Score=301, Evalue=7e-83,
Organism=Saccharomyces cerevisiae, GI6323794, Length=367, Percent_Identity=26.158038147139, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323515, Length=483, Percent_Identity=25.4658385093168, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320118, Length=359, Percent_Identity=23.9554317548747, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 48249; Mature: 48249

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNTTPLVAAPAAPRVPRIVIVGGGAGGLHLATRLGDTIGRRGHTEVVLVDRYPTHFWKP
CCCCCCEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHH
LLHEAASGHRDPASHTIEYAAQAKRHGFRFVQGALQRVDRAARIATIGAVHDADGTEILP
HHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCEECC
ARTLAYDDLVLAVGSVTNFFGVPGAARHALPLENLDQAEDFRRKFLAACTKANHRAEQQP
HHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
AQPAAPVSISVIGAGATGVELAAALRHAVQQLTTYRFKALDGARDVRIRLIEGAPRILPA
CCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHH
LDARLSDKMHAQLRALNVEVLTDTRVAEVGADAVTIASGERLASDITIWAAGVAGPAILR
HHHHHHHHHHHHHHHEEEEEEECCHHHHCCCCEEEEECCCHHHHCEEEEECCCCCHHHHH
ELDGIALNRSNQVIVTDTLQTPDDPHVHAFGDCAACPSNGASGCLPPRAQVAHQQAVYLS
HHCCEEECCCCCEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
QAFARRIAGKPVAGFTFRDAGTVVSLGHAGAVYQAELGVRSRSLIVDGLAAIGLYKFLYR
HHHHHHHCCCCCCCEEECCCCCEEEECCCCCEEEHHCCCCHHHHHHHHHHHHHHHHHHHH
KHLFSVHGIKRALFQSLSHWLQSRNQPSIKLH
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEC
>Mature Secondary Structure
MDNTTPLVAAPAAPRVPRIVIVGGGAGGLHLATRLGDTIGRRGHTEVVLVDRYPTHFWKP
CCCCCCEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHH
LLHEAASGHRDPASHTIEYAAQAKRHGFRFVQGALQRVDRAARIATIGAVHDADGTEILP
HHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCEECC
ARTLAYDDLVLAVGSVTNFFGVPGAARHALPLENLDQAEDFRRKFLAACTKANHRAEQQP
HHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
AQPAAPVSISVIGAGATGVELAAALRHAVQQLTTYRFKALDGARDVRIRLIEGAPRILPA
CCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHH
LDARLSDKMHAQLRALNVEVLTDTRVAEVGADAVTIASGERLASDITIWAAGVAGPAILR
HHHHHHHHHHHHHHHEEEEEEECCHHHHCCCCEEEEECCCHHHHCEEEEECCCCCHHHHH
ELDGIALNRSNQVIVTDTLQTPDDPHVHAFGDCAACPSNGASGCLPPRAQVAHQQAVYLS
HHCCEEECCCCCEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
QAFARRIAGKPVAGFTFRDAGTVVSLGHAGAVYQAELGVRSRSLIVDGLAAIGLYKFLYR
HHHHHHHCCCCCCCEEECCCCCEEEECCCCCEEEHHCCCCHHHHHHHHHHHHHHHHHHHH
KHLFSVHGIKRALFQSLSHWLQSRNQPSIKLH
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]