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The map label for this gene is gra-orf6 [H]

Identifier: 189352012

GI number: 189352012

Start: 30989

End: 31792

Strand: Reverse

Name: gra-orf6 [H]

Synonym: BMULJ_03229

Alternate gene names: 189352012

Gene position: 31792-30989 (Counterclockwise)

Preceding gene: 189352013

Following gene: 189352009

Centisome position: 1.29

GC content: 68.78

Gene sequence:

>804_bases
ATGCAGTCAACGAAGCAAGCGGCGGATGCGCCCGTCGTGCTGGTGACCGGCGCCGCGCGCCGTGCCGGCCGCGCATTCGC
CGAGTATTTCGCCGCGCACGGCTATCGCACCGCCGTGCACTACGACCGCTCGGCCGACGCGGCCGAGGCCGCGGCCCGCG
CGATCGCCGAACGCGGCCCCGACTCCGTCGCGCTGCAGGCCGACTTGTCCGACGAGGCCCAGATCGCGTCGCTGATCGAC
GCCGTGTACGCGCGCTTCGGCCGCCTCGACGTGCTCGTGAACAATGCGTCGGTGTTCTGGCAGGACCATTTCCCGAGCTT
CGATCTCGCCGCGTTCGATCACGCGTGGACCGTGAACTGTCGCGCGCCGATCCTGCTCACGCGCGCGTTCTACGAGCGCG
CGCGCGCCGCGGGCACGCAGGGCGTTGTCGTGAACGTCGTCGATCAGAAGATCAAGGAAAACTTCCATCGCGACCATTTC
AGCTATACGGTCGCGAAGGCGGCGCTCGGCAATCTGACGCAGATGCTCGCGCTGTCGGCCGCGCCCGTGCTGCGCGTGAA
CGCCGTGTTCCCGGGCCTGATGCTGCCGAGCGACGACCAGACGCAGGCCGATTTCGAACACGCGAGCCGCGCGTCGACAC
CGCTCGCGCGCATCGCGGGCCCCGACGACGTCGCGAGCGCGATCCTGCTGCTGACGGGCAGCGCGTACAACGGCGTGGAT
TTCGTCGTCGATGCGGGGCAGAACCTGATTCGCGTCGATCAGGACGTGCTGTACAAGCATCGCTCGCCGAGCAGCCGGCA
CTGA

Upstream 100 bases:

>100_bases
GTCGCGGATGCTCGGCACGTTCCGCACCGATCCGTCGACGCGGCGCGAATTCCTGTCGATCGTCGCGAACCCGTCTTCCG
TGAACCTGACGAATACGTAA

Downstream 100 bases:

>100_bases
CGATCGGCGCGCGCGAAGCGCGCCGCCTTTTGCGCTGCCACAGGCCGCTGCGCCGGCGGCGATTTCGCCGCTCCGGCGTT
GCGCCGATTCCGGCGCTCCG

Product: putative short-chain alcohol dehydrogenase

Products: NA

Alternate protein names: ORF6 [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MQSTKQAADAPVVLVTGAARRAGRAFAEYFAAHGYRTAVHYDRSADAAEAAARAIAERGPDSVALQADLSDEAQIASLID
AVYARFGRLDVLVNNASVFWQDHFPSFDLAAFDHAWTVNCRAPILLTRAFYERARAAGTQGVVVNVVDQKIKENFHRDHF
SYTVAKAALGNLTQMLALSAAPVLRVNAVFPGLMLPSDDQTQADFEHASRASTPLARIAGPDDVASAILLLTGSAYNGVD
FVVDAGQNLIRVDQDVLYKHRSPSSRH

Sequences:

>Translated_267_residues
MQSTKQAADAPVVLVTGAARRAGRAFAEYFAAHGYRTAVHYDRSADAAEAAARAIAERGPDSVALQADLSDEAQIASLID
AVYARFGRLDVLVNNASVFWQDHFPSFDLAAFDHAWTVNCRAPILLTRAFYERARAAGTQGVVVNVVDQKIKENFHRDHF
SYTVAKAALGNLTQMLALSAAPVLRVNAVFPGLMLPSDDQTQADFEHASRASTPLARIAGPDDVASAILLLTGSAYNGVD
FVVDAGQNLIRVDQDVLYKHRSPSSRH
>Mature_267_residues
MQSTKQAADAPVVLVTGAARRAGRAFAEYFAAHGYRTAVHYDRSADAAEAAARAIAERGPDSVALQADLSDEAQIASLID
AVYARFGRLDVLVNNASVFWQDHFPSFDLAAFDHAWTVNCRAPILLTRAFYERARAAGTQGVVVNVVDQKIKENFHRDHF
SYTVAKAALGNLTQMLALSAAPVLRVNAVFPGLMLPSDDQTQADFEHASRASTPLARIAGPDDVASAILLLTGSAYNGVD
FVVDAGQNLIRVDQDVLYKHRSPSSRH

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=223, Percent_Identity=30.9417040358744, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI59889578, Length=231, Percent_Identity=26.4069264069264, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI2367175, Length=226, Percent_Identity=30.0884955752212, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788459, Length=242, Percent_Identity=26.4462809917355, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787335, Length=228, Percent_Identity=27.6315789473684, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787905, Length=230, Percent_Identity=27.8260869565217, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787891, Length=239, Percent_Identity=25.9414225941423, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=26.0162601626016, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790717, Length=244, Percent_Identity=25.8196721311475, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=29.0836653386454, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1789057, Length=188, Percent_Identity=30.3191489361702, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=30.7086614173228, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=30.3149606299213, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=28.8973384030418, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=28.1368821292776, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=28.1368821292776, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=28.5171102661597, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=27.4809160305344, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=263, Percent_Identity=28.5171102661597, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=28.9473684210526, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=27.6515151515151, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=26.4367816091954, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=26.1363636363636, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=27.0992366412214, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=26.4367816091954, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=27.1317829457364, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=259, Percent_Identity=27.027027027027, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=26.7175572519084, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=258, Percent_Identity=25.5813953488372, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=31.8548387096774, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=30.7692307692308, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24644337, Length=255, Percent_Identity=30.9803921568627, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357041, Length=248, Percent_Identity=28.6290322580645, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24644339, Length=247, Percent_Identity=28.3400809716599, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28838; Mature: 28838

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSTKQAADAPVVLVTGAARRAGRAFAEYFAAHGYRTAVHYDRSADAAEAAARAIAERGP
CCCCCHHCCCCEEEEECCHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHCCC
DSVALQADLSDEAQIASLIDAVYARFGRLDVLVNNASVFWQDHFPSFDLAAFDHAWTVNC
CCEEEEECCCCHHHHHHHHHHHHHHHCCEEEEEECCEEEEECCCCCCCCEECCCEEEECC
RAPILLTRAFYERARAAGTQGVVVNVVDQKIKENFHRDHFSYTVAKAALGNLTQMLALSA
CCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APVLRVNAVFPGLMLPSDDQTQADFEHASRASTPLARIAGPDDVASAILLLTGSAYNGVD
CCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHCCCCCCCEE
FVVDAGQNLIRVDQDVLYKHRSPSSRH
EEEECCCCHHHHCHHHHHHCCCCCCCC
>Mature Secondary Structure
MQSTKQAADAPVVLVTGAARRAGRAFAEYFAAHGYRTAVHYDRSADAAEAAARAIAERGP
CCCCCHHCCCCEEEEECCHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHCCC
DSVALQADLSDEAQIASLIDAVYARFGRLDVLVNNASVFWQDHFPSFDLAAFDHAWTVNC
CCEEEEECCCCHHHHHHHHHHHHHHHCCEEEEEECCEEEEECCCCCCCCEECCCEEEECC
RAPILLTRAFYERARAAGTQGVVVNVVDQKIKENFHRDHFSYTVAKAALGNLTQMLALSA
CCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APVLRVNAVFPGLMLPSDDQTQADFEHASRASTPLARIAGPDDVASAILLLTGSAYNGVD
CCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHCCCCCCCEE
FVVDAGQNLIRVDQDVLYKHRSPSSRH
EEEECCCCHHHHCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2583128; 9831526 [H]