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The map label for this gene is traA [H]

Identifier: 189184387

GI number: 189184387

Start: 1506773

End: 1508752

Strand: Direct

Name: traA [H]

Synonym: OTT_1480

Alternate gene names: 189184387

Gene position: 1506773-1508752 (Clockwise)

Preceding gene: 189184385

Following gene: 189184389

Centisome position: 75.0

GC content: 32.93

Gene sequence:

>1980_bases
ATGGCTATACAGTTTACAAGGATTGAATTTTTAACTAGAAGTAAAGGAGGTGATAGTTGTCGTAAGGCAGCTTATAATGC
AAGAACTATTGTTGAAAACGAGAAGACAGGTATAAAGTATAACTTCTCTCGTAAGAAAGATAACGTATATCATACAGTGC
TGATACCGGCTTATGTAAAACAAGAATTCAAGAATATTCAAACATTAATGAATGAGGTAGAACGAACCGCAAAAAACAGA
AACAGCCATTTGTTGAAGGATATAGTAATAGCATTGCCAGACGAGAAGGAGCTAAATTTAGAGCATAGAATAGAACTAAC
TCATCAAATAGTTGATGAAATGGAATGGGTGCAAAAAGGTATTGGAGTACAGATAGACATTCATAAGCCTCAAATAGGAG
ATAAAAACTGGCATGTACATATATTGCTTACTATGAGAAGATTTAGAGAAGATGGAACTGGTTTAGGAGATATAGCAGTA
GATTTAAACCCAAAAATCATAACAGTTAATGGCAAAAAGGTTGTTATTAAAGATCCCGAGATGATTCATGAAAGAGTAAA
AGAAATAATTAATGCATATTTCGCTAAATTAGGCTTACCATATAGAGTTGACGAGAAAAGCAAAGTGCCGGGAAAGCATA
TTGGGAATATTAAATATATTGAAATTAGGAATTTAATTAATGAAGTAGTAAATGAAAATGAGTTACGTAAAGAGGCTCAT
TTGAAGATTATTAATGATGCTGACGTAATAACAGATTCTATAACACATTACAAATCTATTTTTACTAAGCAGGATGTTGA
AAAAGCCGTTCAAGATATACCAGATCCAACAGCAAGAGAACAGTTAGTTCAGCAAGTGCTTAGTTCAAATAGAATACTAG
AGTTATATCATGATGATGGTGAAAGTAGCAAATATTTTACGACAATTGAGGTTCGAAATGAGGAGACGAGAATAATCAGA
ATAGCTAATAAAATCAATGATCAGGTTTATTACAACGATATTTACAATCTTAAAAGTGATATCGAAGGTCTAGCAAATGT
TAGTGAAGAACAGAAACAAGCTCTAAGGCATATTTTGCTTAGCACTAGTGGAGTTAGAGTCTTGAGAGGAAGAGCTGGTA
CAGGAAAATCTTATGTTTTAATAAAAGCGCATAAGCTCGCAACAAATCGTAGACAAAAAGTTATTGGTCTTGCTCCTACT
CATAAGGCAGTATCAGAGCTGAGGAGCAAAGGTTATACAGAGGTCTATACAGTAAAAGGATTTTTGTATAATCGAAAAAA
AAATTTTATGCAAGGCAGCTTAATAGTAGTAGATGAAGCTGGAATGGTAGGTACTAAAGCTTATGCAGAGCTGTTTAGAG
TAGTTAGAAACAATAATTGTCAACTGATACTTGCTGGAGATGAAAAGCAGTTAGCTTCAATAGAAAGAGGTGGAATGTTT
GAGATGCTGAGTAATATTTTTGGTTCACATGTTTTAGTAAATATTCGAAGACAAAGTAAAAACTGGAGCAGAGAAGCAGC
AACAAAGTTTGCTGAGAGTAATATTTTAAGCTGTATAACCTTACTGAGGCAAAATAAATGCGTTAGGTTTGATAATACGT
TGCAGGACTCAATGAGTAAATTAATATACAACTGGAGTCTAAGCAAATTTAAACCACATGAAAAATTGGTAATTACAGTA
CGTAATAAAGATGTCGACATTCTTAATTCAAGTATTAGGTCTTTGTTAAAAGCAAATGGTACGCTAAAAGGCACAGAATA
TGAGCGTTCTATTGATGGAAGGAAAAAGTCATATATGGCAGGAGATAGAATCGTATTTCAAAAAAGCTATAAGGATTTAC
AAATACAAAACAGTGAATTTGCAACTTTAACTTCGGTTAGTAAAAATAAATTTATAGCTAAGACAGACACAGGAAAAGAA
GTGAGTTTTGATCCTAGTAAAATACAATTTAAACATGGCTATGCTACAAATCTCGTTTAA

Upstream 100 bases:

>100_bases
GTACTCATTAACCGATTGAATGTTAAAAAAAAAGAAGTTTGTGCTAGCAAAATCAAAAAAACCATGCTAACTTAAAACTC
AGGTGAGAATTGGTATTGAG

Downstream 100 bases:

>100_bases
CTAATTTTGATATTACTTTGCTATTTTCTATCTAGATCAGTATTTTAGTTAGCTTTCTATCGTGCTTGGCGGCTATAAAA
CAGTTGCCAATTTTGTGCCG

Product: putative conjugative transfer protein TraA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 659; Mature: 658

Protein sequence:

>659_residues
MAIQFTRIEFLTRSKGGDSCRKAAYNARTIVENEKTGIKYNFSRKKDNVYHTVLIPAYVKQEFKNIQTLMNEVERTAKNR
NSHLLKDIVIALPDEKELNLEHRIELTHQIVDEMEWVQKGIGVQIDIHKPQIGDKNWHVHILLTMRRFREDGTGLGDIAV
DLNPKIITVNGKKVVIKDPEMIHERVKEIINAYFAKLGLPYRVDEKSKVPGKHIGNIKYIEIRNLINEVVNENELRKEAH
LKIINDADVITDSITHYKSIFTKQDVEKAVQDIPDPTAREQLVQQVLSSNRILELYHDDGESSKYFTTIEVRNEETRIIR
IANKINDQVYYNDIYNLKSDIEGLANVSEEQKQALRHILLSTSGVRVLRGRAGTGKSYVLIKAHKLATNRRQKVIGLAPT
HKAVSELRSKGYTEVYTVKGFLYNRKKNFMQGSLIVVDEAGMVGTKAYAELFRVVRNNNCQLILAGDEKQLASIERGGMF
EMLSNIFGSHVLVNIRRQSKNWSREAATKFAESNILSCITLLRQNKCVRFDNTLQDSMSKLIYNWSLSKFKPHEKLVITV
RNKDVDILNSSIRSLLKANGTLKGTEYERSIDGRKKSYMAGDRIVFQKSYKDLQIQNSEFATLTSVSKNKFIAKTDTGKE
VSFDPSKIQFKHGYATNLV

Sequences:

>Translated_659_residues
MAIQFTRIEFLTRSKGGDSCRKAAYNARTIVENEKTGIKYNFSRKKDNVYHTVLIPAYVKQEFKNIQTLMNEVERTAKNR
NSHLLKDIVIALPDEKELNLEHRIELTHQIVDEMEWVQKGIGVQIDIHKPQIGDKNWHVHILLTMRRFREDGTGLGDIAV
DLNPKIITVNGKKVVIKDPEMIHERVKEIINAYFAKLGLPYRVDEKSKVPGKHIGNIKYIEIRNLINEVVNENELRKEAH
LKIINDADVITDSITHYKSIFTKQDVEKAVQDIPDPTAREQLVQQVLSSNRILELYHDDGESSKYFTTIEVRNEETRIIR
IANKINDQVYYNDIYNLKSDIEGLANVSEEQKQALRHILLSTSGVRVLRGRAGTGKSYVLIKAHKLATNRRQKVIGLAPT
HKAVSELRSKGYTEVYTVKGFLYNRKKNFMQGSLIVVDEAGMVGTKAYAELFRVVRNNNCQLILAGDEKQLASIERGGMF
EMLSNIFGSHVLVNIRRQSKNWSREAATKFAESNILSCITLLRQNKCVRFDNTLQDSMSKLIYNWSLSKFKPHEKLVITV
RNKDVDILNSSIRSLLKANGTLKGTEYERSIDGRKKSYMAGDRIVFQKSYKDLQIQNSEFATLTSVSKNKFIAKTDTGKE
VSFDPSKIQFKHGYATNLV
>Mature_658_residues
AIQFTRIEFLTRSKGGDSCRKAAYNARTIVENEKTGIKYNFSRKKDNVYHTVLIPAYVKQEFKNIQTLMNEVERTAKNRN
SHLLKDIVIALPDEKELNLEHRIELTHQIVDEMEWVQKGIGVQIDIHKPQIGDKNWHVHILLTMRRFREDGTGLGDIAVD
LNPKIITVNGKKVVIKDPEMIHERVKEIINAYFAKLGLPYRVDEKSKVPGKHIGNIKYIEIRNLINEVVNENELRKEAHL
KIINDADVITDSITHYKSIFTKQDVEKAVQDIPDPTAREQLVQQVLSSNRILELYHDDGESSKYFTTIEVRNEETRIIRI
ANKINDQVYYNDIYNLKSDIEGLANVSEEQKQALRHILLSTSGVRVLRGRAGTGKSYVLIKAHKLATNRRQKVIGLAPTH
KAVSELRSKGYTEVYTVKGFLYNRKKNFMQGSLIVVDEAGMVGTKAYAELFRVVRNNNCQLILAGDEKQLASIERGGMFE
MLSNIFGSHVLVNIRRQSKNWSREAATKFAESNILSCITLLRQNKCVRFDNTLQDSMSKLIYNWSLSKFKPHEKLVITVR
NKDVDILNSSIRSLLKANGTLKGTEYERSIDGRKKSYMAGDRIVFQKSYKDLQIQNSEFATLTSVSKNKFIAKTDTGKEV
SFDPSKIQFKHGYATNLV

Specific function: traI Has Been Identified As DNA Helicase I And It Also Has An Additional Activity Of Site-Specific Nicking At Orit. DNA Helicase I Is A Potent DNA-Dependent ATPase. [C]

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mobA/mobL family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000606
- InterPro:   IPR005053
- InterPro:   IPR014136 [H]

Pfam domain/function: PF03389 MobA_MobL; PF01443 Viral_helicase1 [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 75475; Mature: 75344

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIQFTRIEFLTRSKGGDSCRKAAYNARTIVENEKTGIKYNFSRKKDNVYHTVLIPAYVK
CCEEEEEEHHEECCCCCCHHHHHHCCCCEEEECCCCCEEEEECCCCCCEEEEEEEHHHHH
QEFKNIQTLMNEVERTAKNRNSHLLKDIVIALPDEKELNLEHRIELTHQIVDEMEWVQKG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHC
IGVQIDIHKPQIGDKNWHVHILLTMRRFREDGTGLGDIAVDLNPKIITVNGKKVVIKDPE
CCEEEEEECCCCCCCCEEEEEEEEHHHHHHCCCCCCEEEEECCCEEEEECCCEEEEECHH
MIHERVKEIINAYFAKLGLPYRVDEKSKVPGKHIGNIKYIEIRNLINEVVNENELRKEAH
HHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEHHHHHHHHHHCHHHHHHHHC
LKIINDADVITDSITHYKSIFTKQDVEKAVQDIPDPTAREQLVQQVLSSNRILELYHDDG
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCC
ESSKYFTTIEVRNEETRIIRIANKINDQVYYNDIYNLKSDIEGLANVSEEQKQALRHILL
CCCEEEEEEEEECCCCEEEEEEHHHCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
STSGVRVLRGRAGTGKSYVLIKAHKLATNRRQKVIGLAPTHKAVSELRSKGYTEVYTVKG
CCCCCEEEECCCCCCCEEEEEEEHHHHCCCCCEEEEECCCHHHHHHHHHCCCCEEEEEEH
FLYNRKKNFMQGSLIVVDEAGMVGTKAYAELFRVVRNNNCQLILAGDEKQLASIERGGMF
EEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCHH
EMLSNIFGSHVLVNIRRQSKNWSREAATKFAESNILSCITLLRQNKCVRFDNTLQDSMSK
HHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHH
LIYNWSLSKFKPHEKLVITVRNKDVDILNSSIRSLLKANGTLKGTEYERSIDGRKKSYMA
HHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHCC
GDRIVFQKSYKDLQIQNSEFATLTSVSKNKFIAKTDTGKEVSFDPSKIQFKHGYATNLV
CCEEEEEECCCCCEECCCCCEEEEECCCCCEEEECCCCCCCCCCCCCEEEECCCCCCCC
>Mature Secondary Structure 
AIQFTRIEFLTRSKGGDSCRKAAYNARTIVENEKTGIKYNFSRKKDNVYHTVLIPAYVK
CEEEEEEHHEECCCCCCHHHHHHCCCCEEEECCCCCEEEEECCCCCCEEEEEEEHHHHH
QEFKNIQTLMNEVERTAKNRNSHLLKDIVIALPDEKELNLEHRIELTHQIVDEMEWVQKG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHC
IGVQIDIHKPQIGDKNWHVHILLTMRRFREDGTGLGDIAVDLNPKIITVNGKKVVIKDPE
CCEEEEEECCCCCCCCEEEEEEEEHHHHHHCCCCCCEEEEECCCEEEEECCCEEEEECHH
MIHERVKEIINAYFAKLGLPYRVDEKSKVPGKHIGNIKYIEIRNLINEVVNENELRKEAH
HHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEHHHHHHHHHHCHHHHHHHHC
LKIINDADVITDSITHYKSIFTKQDVEKAVQDIPDPTAREQLVQQVLSSNRILELYHDDG
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCC
ESSKYFTTIEVRNEETRIIRIANKINDQVYYNDIYNLKSDIEGLANVSEEQKQALRHILL
CCCEEEEEEEEECCCCEEEEEEHHHCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
STSGVRVLRGRAGTGKSYVLIKAHKLATNRRQKVIGLAPTHKAVSELRSKGYTEVYTVKG
CCCCCEEEECCCCCCCEEEEEEEHHHHCCCCCEEEEECCCHHHHHHHHHCCCCEEEEEEH
FLYNRKKNFMQGSLIVVDEAGMVGTKAYAELFRVVRNNNCQLILAGDEKQLASIERGGMF
EEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCHH
EMLSNIFGSHVLVNIRRQSKNWSREAATKFAESNILSCITLLRQNKCVRFDNTLQDSMSK
HHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHH
LIYNWSLSKFKPHEKLVITVRNKDVDILNSSIRSLLKANGTLKGTEYERSIDGRKKSYMA
HHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHCC
GDRIVFQKSYKDLQIQNSEFATLTSVSKNKFIAKTDTGKEVSFDPSKIQFKHGYATNLV
CCEEEEEECCCCCEECCCCCEEEEECCCCCEEEECCCCCCCCCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8763953; 11743193; 11743194 [H]