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The map label for this gene is asd [H]

Identifier: 189184101

GI number: 189184101

Start: 1222346

End: 1223383

Strand: Direct

Name: asd [H]

Synonym: OTT_1194

Alternate gene names: 189184101

Gene position: 1222346-1223383 (Clockwise)

Preceding gene: 189184100

Following gene: 189184105

Centisome position: 60.84

GC content: 29.48

Gene sequence:

>1038_bases
ATGAATAATAAAATTAACATAGCGGTTATAGGTGCTACAGGTAATGTAGGCAGGTTATTAATTGATATTTTATATGAAAG
GCAACTGCCAATAAGGCATCTTTATTGTATATCTAATAATTTAATTGGACATAACATAAGTTTTGGACAACAAAATATTG
TTACTCAGTCTATAAAAAATTTTGATTTTAGAGGTATTAATATAGTATTTTCTTGCGTTAATGCTCAAGTTGCAAAATCT
ATTGTTCCAAAGATAGTATCAGCAGGGGCAAAAGTAATTGATAAGTCATCTTATTTTAGACTGAAGAGTGATATTCCTTT
AGTTATACCAGAAATAAATATTGATACTATTACAACTAATTCACGTATTATATCTAGCCCAAATTGTTGTGTAGTCCCAT
TAATATTAGTTCTAAAGCCATTAGATGATGTTGCTAAAATTAAAAAATTAGTTATTGCAACATATCAATCTACTTCAGGT
GCAGGGAAAGCTGCAATGGAAGAATTAGATATGCAAACTAGAAATCGGTATTTAGAACAATCGAAAACATTAACTCCGCA
AATTTTTCCTAAGCAGATTGCTTTTAATATCATACCTCAGATAGGAATGATCATGGAGAATGGTAGGTGTGATGAAGAAG
ATAAAATAATTCGTGAAATACAAAAAATTATTGGTCGTCAAATTGCTATATCAATTACCTGTGTAAGAGTGCCAACATTT
GTTAGCCACGCTTTTGCAGTTAATGTTGAATTTGAATATAATTTAAGCGTGAAAGATGCAGAATCATTGCTTGTAAAGCT
TAATGGTATTAAATTAATCAGTAATGTCAAGAATAGTATGAGTAATACAAGCTCAGATATTGTTACTCCAGTTGATGTTA
CTGGAAAAAACGATGTTTTTGTTAGCAGAGTAAGAAAAGAGAAAAATATAAAGAATAGTTTGAGTTTATGGATAAGTACG
GATAATTTGCGAAAAGGATCAGCACTTAATGCAGTACAAATTGCTGAAAATATTCTTTTGCAACAAAAATTAATATAA

Upstream 100 bases:

>100_bases
ATACTCATATCATTTCAAATCAGAAAATTGAGTCAAATTAATATATTTTAAGCGTATTATTAAAAATACGCTCTTATATG
TTTGGTATATAATAAATGTG

Downstream 100 bases:

>100_bases
TTATAAAAGTTAAGATAGTTATAGGTAAATTTTGCTGTTTAAAGTCGTAGCAAAACAACTATAAGAGATTTATACTTCAA
AATACATGAATGTTATAGAT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MNNKINIAVIGATGNVGRLLIDILYERQLPIRHLYCISNNLIGHNISFGQQNIVTQSIKNFDFRGINIVFSCVNAQVAKS
IVPKIVSAGAKVIDKSSYFRLKSDIPLVIPEINIDTITTNSRIISSPNCCVVPLILVLKPLDDVAKIKKLVIATYQSTSG
AGKAAMEELDMQTRNRYLEQSKTLTPQIFPKQIAFNIIPQIGMIMENGRCDEEDKIIREIQKIIGRQIAISITCVRVPTF
VSHAFAVNVEFEYNLSVKDAESLLVKLNGIKLISNVKNSMSNTSSDIVTPVDVTGKNDVFVSRVRKEKNIKNSLSLWIST
DNLRKGSALNAVQIAENILLQQKLI

Sequences:

>Translated_345_residues
MNNKINIAVIGATGNVGRLLIDILYERQLPIRHLYCISNNLIGHNISFGQQNIVTQSIKNFDFRGINIVFSCVNAQVAKS
IVPKIVSAGAKVIDKSSYFRLKSDIPLVIPEINIDTITTNSRIISSPNCCVVPLILVLKPLDDVAKIKKLVIATYQSTSG
AGKAAMEELDMQTRNRYLEQSKTLTPQIFPKQIAFNIIPQIGMIMENGRCDEEDKIIREIQKIIGRQIAISITCVRVPTF
VSHAFAVNVEFEYNLSVKDAESLLVKLNGIKLISNVKNSMSNTSSDIVTPVDVTGKNDVFVSRVRKEKNIKNSLSLWIST
DNLRKGSALNAVQIAENILLQQKLI
>Mature_345_residues
MNNKINIAVIGATGNVGRLLIDILYERQLPIRHLYCISNNLIGHNISFGQQNIVTQSIKNFDFRGINIVFSCVNAQVAKS
IVPKIVSAGAKVIDKSSYFRLKSDIPLVIPEINIDTITTNSRIISSPNCCVVPLILVLKPLDDVAKIKKLVIATYQSTSG
AGKAAMEELDMQTRNRYLEQSKTLTPQIFPKQIAFNIIPQIGMIMENGRCDEEDKIIREIQKIIGRQIAISITCVRVPTF
VSHAFAVNVEFEYNLSVKDAESLLVKLNGIKLISNVKNSMSNTSSDIVTPVDVTGKNDVFVSRVRKEKNIKNSLSLWIST
DNLRKGSALNAVQIAENILLQQKLI

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=348, Percent_Identity=31.0344827586207, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789841, Length=357, Percent_Identity=26.890756302521, Blast_Score=96, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6320362, Length=294, Percent_Identity=24.8299319727891, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 38277; Mature: 38277

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNKINIAVIGATGNVGRLLIDILYERQLPIRHLYCISNNLIGHNISFGQQNIVTQSIKN
CCCEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHC
FDFRGINIVFSCVNAQVAKSIVPKIVSAGAKVIDKSSYFRLKSDIPLVIPEINIDTITTN
CCCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHCCCCCCEEEECCCCEEEECCCEEEEECC
SRIISSPNCCVVPLILVLKPLDDVAKIKKLVIATYQSTSGAGKAAMEELDMQTRNRYLEQ
CEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHH
SKTLTPQIFPKQIAFNIIPQIGMIMENGRCDEEDKIIREIQKIIGRQIAISITCVRVPTF
HCCCCCCCCHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCCEEEEEEEEEEHHHH
VSHAFAVNVEFEYNLSVKDAESLLVKLNGIKLISNVKNSMSNTSSDIVTPVDVTGKNDVF
HCCEEEEEEEEEEECCCCCHHEEEEEECCCHHHHHHHHHHCCCCCCCEEEEECCCCCCHH
VSRVRKEKNIKNSLSLWISTDNLRKGSALNAVQIAENILLQQKLI
HHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNNKINIAVIGATGNVGRLLIDILYERQLPIRHLYCISNNLIGHNISFGQQNIVTQSIKN
CCCEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHC
FDFRGINIVFSCVNAQVAKSIVPKIVSAGAKVIDKSSYFRLKSDIPLVIPEINIDTITTN
CCCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHCCCCCCEEEECCCCEEEECCCEEEEECC
SRIISSPNCCVVPLILVLKPLDDVAKIKKLVIATYQSTSGAGKAAMEELDMQTRNRYLEQ
CEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHH
SKTLTPQIFPKQIAFNIIPQIGMIMENGRCDEEDKIIREIQKIIGRQIAISITCVRVPTF
HCCCCCCCCHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCCEEEEEEEEEEHHHH
VSHAFAVNVEFEYNLSVKDAESLLVKLNGIKLISNVKNSMSNTSSDIVTPVDVTGKNDVF
HCCEEEEEEEEEEECCCCCHHEEEEEECCCHHHHHHHHHHCCCCCCCEEEEECCCCCCHH
VSRVRKEKNIKNSLSLWISTDNLRKGSALNAVQIAENILLQQKLI
HHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA