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The map label for this gene is traA [H]

Identifier: 189184041

GI number: 189184041

Start: 1162791

End: 1165196

Strand: Direct

Name: traA [H]

Synonym: OTT_1134

Alternate gene names: 189184041

Gene position: 1162791-1165196 (Clockwise)

Preceding gene: 189184040

Following gene: 189184042

Centisome position: 57.88

GC content: 33.92

Gene sequence:

>2406_bases
TTGGTTACTACAAGAAGATTTAAAGAGAATGGCGAAGAATTGGGTGGTAAAGCTGTTGACTTGGAGCCTAAATTCAGAAC
ATCGAAAGGTAAGGCGTTTATTATTCCAGAAGCTGAGATGATTCATGAAAAAGTGAAGGAAATAATTAATGCATATTTTG
CTAAATTAGGCTTATCAAATAGAGTTGATGATATAAGTATAGTGCCACAGAAGCATATTGGACCTACTAGAATTAGGAGT
TTAATTAATGAAGTAGCAAATGAAAATGAGTTACGTAAAGAGGCTAATTTAAAAATTATTAAGGATGCTGATGTAATAAC
GGATTCTATAACACATTACAAATCTATTTTTACTAAGCAGGATGTTGAAAAAGCCGTGAAAGATATACCAGACCTAACAG
CAAGAGAACGGTTAGTTCAACAAGTGCTCAGTTCAAATAGAGTATTAGAATTGTATCATGAGAATGGTGAAAGTAGCAAA
TATTTTACTACAACTGAGGTTAGAGACGAGGAAGTAAGAATAATAAGAATAGCTAATAAAATCAATGATCAGGTTTATTA
CAACGATATTTACAATCTTAAAAGCGATATAGAAGGACTAACAAATGTTAGTGAAGAACAGAAACAAGCTCTAAGGCATA
TTTTGCTTAGTACTAGTGGAGTTAGAGTCTTAAGAGGAAGAGCTGGTACAGGAAAATCTCATGTTTTAGCGAAAGCATAT
GAGCTTGCAACAAATCGTGGACAAAAAGTTATTGGTCTTGCTCCTACTCATAAAGCGGTATCAGAGCTGAGGAGCAAAGG
CTATACAGAGGTCTATACAGTAAAAGGATTTTTGTATAATCGAAAAAAAATTTTTATGCAAGGCAGCTTAATAGTAGTAG
ATGAAGCTGGAATGGTAGGTACTAAAGCTTATGCAGAGCTGTTTAGAGTAGTTAGAAACAATAATTGTCAACTGATACTT
GCTGGAGATGAAAAGCAGTTAGCTTCTATAGAAAGAGGCGGAATGTTTGAGATGCTGAGTAATATTTTCGGTTCACATGT
TTTAGTAAATATTCGAAGACAAAGTGAAAACTGGAGCAGAGAAGCAGCAACAAAATTTGCTGAGAGTAATATTTTAAGCG
GTATAACATTACTGAAACAAAATAACTGCGTTAAGTTTGATAATACGTTGCAGGACTCAATGAGTAAGCTAGTATATAAC
TGGAGTCTAAGCAAGTTTAAGCCACATGAAAAATTGGTAATTACAGTACGTAATAAAGATGTCGACATTCTTAATTCAAG
TATTAGATCTTTGCTAAAAGCCAATGGCACGCTACAAGGTCCAGAATATAGGCGTTCAATTGCTGGAAGGAAAGAGTCGT
ATATGGCAGGAGATAGAATTGTCTTTCAAGCAAGCAATAAGGATTTACAAATACAAAACAGTGATTTTGCAACTTTAACT
TCGGTTAATAAAAATGAATTTGTAGCTAAGACAGACGCAGGAAAAGAGGTGAGTTTTGATCCTAGTAAAATACAATTTAA
ACATGGCTATGCAAGTACTGTTTATAAGGCGCAGGGAGCTTCTATAAAAGATGTATACGTTTTGCATAATGGAGTAAGTA
ATATAAGCAGCTCATACGTAGCTATGACAAGGCATATAGAGAAATTACAGCTATATTGCAATAAGGAAGCTACTAAAAGC
ATTAACAGCTTAATAAATCAGCTCAGCAGACCAAATGAGAAATCAGCTAGCATAACTCTGAAAACTGCTCATGATTTGGA
GAAAGAACAGACAAAGACAACTGTTTTTAGTAAAATCGAAAACTGGTTTAAGTCCGTAATCAATGATATCAATGATAGAT
CTCATGTGAATGAAGAATATTATCATTTTACCGTTAAACCAGATCAAGAAGCTAAAGTAGAAAGAGTCCAGCAAGAGAAT
CGCATAAAGCAATGTTCATACAAAGATCTGTCTACTCCATTGTTTATGCAAATCAAAGAGCAAAGACAGTACAATTATGA
TGTAACCCTTTTATCTGCAGAAGGAAAAACGATATCAAGCTTCCAGGAGATCGGTATTGATAGCAGAATGGTATATAGCT
CAAATGTAAATAATTTGAAGTACTATCAACCATTTCAAGGAGAAAAGATTCTTATAGCTGCAAATAATGATAAACAGAAT
AAGGAATATATAAGCACTATAAATGAGGCTGCAACAGCATTAAAAAGCAAAGGAGCAATTACTAGCATTGTAATTCCTTC
AGAAGGCGAAGATTTTAACGAAATGCTAAAAAACAAAGGATCCATAGCTGTTAAGGCCTTTGTGATACCTGAAATCATGA
AATTAGTTAATACTCAGAACGTAGAAACACATCCTGAACAAATTGTAAAAGCTGATATAGCTCTAAAAATTGGAATTAGA
AGGTAG

Upstream 100 bases:

>100_bases
TCAAATAGTTGATGCAATGGAATGGGTGCAAAATGGCCTTGGAGTACAGATAGACATTCATAAGCCTCATATATGAGATA
AAAACTGGCATGCGCATATA

Downstream 100 bases:

>100_bases
TGCTGAAGATTTGAAATTGAATATAAGCTGTTCATTTACGGAGCGAATTACAAAATGAGCTATACATGATAGTTGAGATG
GACTTTTGTAATTCGCATTA

Product: putative conjugative transfer protein TraA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 801; Mature: 801

Protein sequence:

>801_residues
MVTTRRFKENGEELGGKAVDLEPKFRTSKGKAFIIPEAEMIHEKVKEIINAYFAKLGLSNRVDDISIVPQKHIGPTRIRS
LINEVANENELRKEANLKIIKDADVITDSITHYKSIFTKQDVEKAVKDIPDLTARERLVQQVLSSNRVLELYHENGESSK
YFTTTEVRDEEVRIIRIANKINDQVYYNDIYNLKSDIEGLTNVSEEQKQALRHILLSTSGVRVLRGRAGTGKSHVLAKAY
ELATNRGQKVIGLAPTHKAVSELRSKGYTEVYTVKGFLYNRKKIFMQGSLIVVDEAGMVGTKAYAELFRVVRNNNCQLIL
AGDEKQLASIERGGMFEMLSNIFGSHVLVNIRRQSENWSREAATKFAESNILSGITLLKQNNCVKFDNTLQDSMSKLVYN
WSLSKFKPHEKLVITVRNKDVDILNSSIRSLLKANGTLQGPEYRRSIAGRKESYMAGDRIVFQASNKDLQIQNSDFATLT
SVNKNEFVAKTDAGKEVSFDPSKIQFKHGYASTVYKAQGASIKDVYVLHNGVSNISSSYVAMTRHIEKLQLYCNKEATKS
INSLINQLSRPNEKSASITLKTAHDLEKEQTKTTVFSKIENWFKSVINDINDRSHVNEEYYHFTVKPDQEAKVERVQQEN
RIKQCSYKDLSTPLFMQIKEQRQYNYDVTLLSAEGKTISSFQEIGIDSRMVYSSNVNNLKYYQPFQGEKILIAANNDKQN
KEYISTINEAATALKSKGAITSIVIPSEGEDFNEMLKNKGSIAVKAFVIPEIMKLVNTQNVETHPEQIVKADIALKIGIR
R

Sequences:

>Translated_801_residues
MVTTRRFKENGEELGGKAVDLEPKFRTSKGKAFIIPEAEMIHEKVKEIINAYFAKLGLSNRVDDISIVPQKHIGPTRIRS
LINEVANENELRKEANLKIIKDADVITDSITHYKSIFTKQDVEKAVKDIPDLTARERLVQQVLSSNRVLELYHENGESSK
YFTTTEVRDEEVRIIRIANKINDQVYYNDIYNLKSDIEGLTNVSEEQKQALRHILLSTSGVRVLRGRAGTGKSHVLAKAY
ELATNRGQKVIGLAPTHKAVSELRSKGYTEVYTVKGFLYNRKKIFMQGSLIVVDEAGMVGTKAYAELFRVVRNNNCQLIL
AGDEKQLASIERGGMFEMLSNIFGSHVLVNIRRQSENWSREAATKFAESNILSGITLLKQNNCVKFDNTLQDSMSKLVYN
WSLSKFKPHEKLVITVRNKDVDILNSSIRSLLKANGTLQGPEYRRSIAGRKESYMAGDRIVFQASNKDLQIQNSDFATLT
SVNKNEFVAKTDAGKEVSFDPSKIQFKHGYASTVYKAQGASIKDVYVLHNGVSNISSSYVAMTRHIEKLQLYCNKEATKS
INSLINQLSRPNEKSASITLKTAHDLEKEQTKTTVFSKIENWFKSVINDINDRSHVNEEYYHFTVKPDQEAKVERVQQEN
RIKQCSYKDLSTPLFMQIKEQRQYNYDVTLLSAEGKTISSFQEIGIDSRMVYSSNVNNLKYYQPFQGEKILIAANNDKQN
KEYISTINEAATALKSKGAITSIVIPSEGEDFNEMLKNKGSIAVKAFVIPEIMKLVNTQNVETHPEQIVKADIALKIGIR
R
>Mature_801_residues
MVTTRRFKENGEELGGKAVDLEPKFRTSKGKAFIIPEAEMIHEKVKEIINAYFAKLGLSNRVDDISIVPQKHIGPTRIRS
LINEVANENELRKEANLKIIKDADVITDSITHYKSIFTKQDVEKAVKDIPDLTARERLVQQVLSSNRVLELYHENGESSK
YFTTTEVRDEEVRIIRIANKINDQVYYNDIYNLKSDIEGLTNVSEEQKQALRHILLSTSGVRVLRGRAGTGKSHVLAKAY
ELATNRGQKVIGLAPTHKAVSELRSKGYTEVYTVKGFLYNRKKIFMQGSLIVVDEAGMVGTKAYAELFRVVRNNNCQLIL
AGDEKQLASIERGGMFEMLSNIFGSHVLVNIRRQSENWSREAATKFAESNILSGITLLKQNNCVKFDNTLQDSMSKLVYN
WSLSKFKPHEKLVITVRNKDVDILNSSIRSLLKANGTLQGPEYRRSIAGRKESYMAGDRIVFQASNKDLQIQNSDFATLT
SVNKNEFVAKTDAGKEVSFDPSKIQFKHGYASTVYKAQGASIKDVYVLHNGVSNISSSYVAMTRHIEKLQLYCNKEATKS
INSLINQLSRPNEKSASITLKTAHDLEKEQTKTTVFSKIENWFKSVINDINDRSHVNEEYYHFTVKPDQEAKVERVQQEN
RIKQCSYKDLSTPLFMQIKEQRQYNYDVTLLSAEGKTISSFQEIGIDSRMVYSSNVNNLKYYQPFQGEKILIAANNDKQN
KEYISTINEAATALKSKGAITSIVIPSEGEDFNEMLKNKGSIAVKAFVIPEIMKLVNTQNVETHPEQIVKADIALKIGIR
R

Specific function: traI Has Been Identified As DNA Helicase I And It Also Has An Additional Activity Of Site-Specific Nicking At Orit. DNA Helicase I Is A Potent DNA-Dependent ATPase. [C]

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mobA/mobL family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000606
- InterPro:   IPR005053
- InterPro:   IPR014136 [H]

Pfam domain/function: PF03389 MobA_MobL; PF01443 Viral_helicase1 [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 90653; Mature: 90653

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTTRRFKENGEELGGKAVDLEPKFRTSKGKAFIIPEAEMIHEKVKEIINAYFAKLGLSN
CCCCHHHHHCHHHHCCEEEECCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCC
RVDDISIVPQKHIGPTRIRSLINEVANENELRKEANLKIIKDADVITDSITHYKSIFTKQ
CCCCEEECCCCCCCHHHHHHHHHHHHCHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHH
DVEKAVKDIPDLTARERLVQQVLSSNRVLELYHENGESSKYFTTTEVRDEEVRIIRIANK
HHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCCEEEEEEEHH
INDQVYYNDIYNLKSDIEGLTNVSEEQKQALRHILLSTSGVRVLRGRAGTGKSHVLAKAY
HCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHH
ELATNRGQKVIGLAPTHKAVSELRSKGYTEVYTVKGFLYNRKKIFMQGSLIVVDEAGMVG
HHHHCCCCEEEEECCCHHHHHHHHHCCCCEEEEEEEEEECCEEEEEECCEEEEECCCCCC
TKAYAELFRVVRNNNCQLILAGDEKQLASIERGGMFEMLSNIFGSHVLVNIRRQSENWSR
HHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCHHHHHHHHCCCEEEEEEEECCCCCHH
EAATKFAESNILSGITLLKQNNCVKFDNTLQDSMSKLVYNWSLSKFKPHEKLVITVRNKD
HHHHHHHHHHHHHHHHEEECCCCEECCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCC
VDILNSSIRSLLKANGTLQGPEYRRSIAGRKESYMAGDRIVFQASNKDLQIQNSDFATLT
HHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHCCCCEEEEEECCCCEEEECCCCEEEE
SVNKNEFVAKTDAGKEVSFDPSKIQFKHGYASTVYKAQGASIKDVYVLHNGVSNISSSYV
ECCCCCEEEECCCCCCCCCCCCCEEEECCCHHHEEECCCCCCEEEEEEECCHHHHHHHHH
AMTRHIEKLQLYCNKEATKSINSLINQLSRPNEKSASITLKTAHDLEKEQTKTTVFSKIE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHH
NWFKSVINDINDRSHVNEEYYHFTVKPDQEAKVERVQQENRIKQCSYKDLSTPLFMQIKE
HHHHHHHHHCCCHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
QRQYNYDVTLLSAEGKTISSFQEIGIDSRMVYSSNVNNLKYYQPFQGEKILIAANNDKQN
HHCCCCCEEEEECCCCCHHHHHHCCCCCEEEEECCCCCCEEECCCCCCEEEEEECCCCCH
KEYISTINEAATALKSKGAITSIVIPSEGEDFNEMLKNKGSIAVKAFVIPEIMKLVNTQN
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHCCCCEEEEEHHHHHHHHHHCCCC
VETHPEQIVKADIALKIGIRR
CCCCHHHHHHHHEEEEEECCC
>Mature Secondary Structure
MVTTRRFKENGEELGGKAVDLEPKFRTSKGKAFIIPEAEMIHEKVKEIINAYFAKLGLSN
CCCCHHHHHCHHHHCCEEEECCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCC
RVDDISIVPQKHIGPTRIRSLINEVANENELRKEANLKIIKDADVITDSITHYKSIFTKQ
CCCCEEECCCCCCCHHHHHHHHHHHHCHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHH
DVEKAVKDIPDLTARERLVQQVLSSNRVLELYHENGESSKYFTTTEVRDEEVRIIRIANK
HHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCCEEEEEEEHH
INDQVYYNDIYNLKSDIEGLTNVSEEQKQALRHILLSTSGVRVLRGRAGTGKSHVLAKAY
HCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHH
ELATNRGQKVIGLAPTHKAVSELRSKGYTEVYTVKGFLYNRKKIFMQGSLIVVDEAGMVG
HHHHCCCCEEEEECCCHHHHHHHHHCCCCEEEEEEEEEECCEEEEEECCEEEEECCCCCC
TKAYAELFRVVRNNNCQLILAGDEKQLASIERGGMFEMLSNIFGSHVLVNIRRQSENWSR
HHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCHHHHHHHHCCCEEEEEEEECCCCCHH
EAATKFAESNILSGITLLKQNNCVKFDNTLQDSMSKLVYNWSLSKFKPHEKLVITVRNKD
HHHHHHHHHHHHHHHHEEECCCCEECCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCC
VDILNSSIRSLLKANGTLQGPEYRRSIAGRKESYMAGDRIVFQASNKDLQIQNSDFATLT
HHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHCCCCEEEEEECCCCEEEECCCCEEEE
SVNKNEFVAKTDAGKEVSFDPSKIQFKHGYASTVYKAQGASIKDVYVLHNGVSNISSSYV
ECCCCCEEEECCCCCCCCCCCCCEEEECCCHHHEEECCCCCCEEEEEEECCHHHHHHHHH
AMTRHIEKLQLYCNKEATKSINSLINQLSRPNEKSASITLKTAHDLEKEQTKTTVFSKIE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHH
NWFKSVINDINDRSHVNEEYYHFTVKPDQEAKVERVQQENRIKQCSYKDLSTPLFMQIKE
HHHHHHHHHCCCHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
QRQYNYDVTLLSAEGKTISSFQEIGIDSRMVYSSNVNNLKYYQPFQGEKILIAANNDKQN
HHCCCCCEEEEECCCCCHHHHHHCCCCCEEEEECCCCCCEEECCCCCCEEEEEECCCCCH
KEYISTINEAATALKSKGAITSIVIPSEGEDFNEMLKNKGSIAVKAFVIPEIMKLVNTQN
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHCCCCEEEEEHHHHHHHHHHCCCC
VETHPEQIVKADIALKIGIRR
CCCCHHHHHHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8763953; 11743193; 11743194 [H]