Click here to switch to the map view.

The map label for this gene is ptrB [H]

Identifier: 189183978

GI number: 189183978

Start: 1097935

End: 1099995

Strand: Direct

Name: ptrB [H]

Synonym: OTT_1071

Alternate gene names: 189183978

Gene position: 1097935-1099995 (Clockwise)

Preceding gene: 189183977

Following gene: 189183979

Centisome position: 54.65

GC content: 29.11

Gene sequence:

>2061_bases
ATGTCAACTTCTATAGCTCACCCAATAGCAAAGAAAGTACCATATAGTTTTACTGTAAATAATAATAAAATCAGTGATGA
TTTTGCATGGCTTAGGGATCGTAAATGGCCAAAACAGGTAAAAGATAAGTCAATATTAGCTTATCTTGAGGCTGAGAATA
ATTATGCTGATGCATATTTTAGTAAATATCAGCCAATGATTACTGAAATATATGAAGAGTTGAAGTCTAGAATAAAACTA
ACTGATCAGTCAGCATATACCAAAAAGAAAAATTATTTTTATTATATCAGAACAGAAGCTGAGAAAGCATATCAAATTTT
TTGTCGAAAATATGGTAGTATTAATGCTCAGGAAGAAATAATATTAGATGTAAATGAATTAGCTGAGCATTGCTCATTTG
TATCAGTTGGTACTTTTAGTGTATCACCAGATAATAATTATGTTGCTTATTCAGTTGATTATGATGGTAGTGAGCGCTAT
AAGATTAGAGTGCTTGATCTTAAGACTAATACTTATTTAGCAGATGAAATAACTCAAGTTATTGGCGGTATAGTATGGCA
TGAAGCTATTTGTGGTTTTTTCTATACTAAAACAAATGAATATTGGCGTTCAGATAAAGTGTTCTTTCATAAACTTAATT
GTAACCCAGAAGATGATCAATTGATTTTCGAGGAAGGGAATGCTTTATATAATCTTGTTATTCAAAAATCTAGTGATGAT
AAATATCTCTTTATTGAATCATCAGGTCATGATAATAATGAATATTATTTTGTTAGTACTGAAAATACAAGCCTAGCTCC
TTATATAATTCAGCCACGTATGCCTAAAGTAATATATGATGTGGAGCATTATAATGGAGAGTTTTTTATTTTAACTAACG
ATATAAATGAAAATTTTAGGCTTGTAGTGACTAAAGTAGAGAATCCTAGTCAAAGATATTGGAAAACTTTTCTTGAATTT
AATGAGAATGAATATTTAAAATCATTTGATATCTCTAAGAGTTGTTTAATTATTACATATAAAGTCAATGGTCTTAGCGC
AATTAAAATATTAAACTTTATAAATAATGAAATTAAAACTTTAAACTTTGATGAAGCAGCTTTTTCAGCTATAGCTTATA
CTAGTAATTTTGAGGAGGATGATATTAGGGTTGAATATTCTTCTCTAAGACAGCCTAAAATACTTTATCAATATGATTTA
GTTTTAGGTAAGCTAAATATCTTGAAAAAAAATGAGGTTCTTGGAAATTTTAATTCTGAAGAGTATCAAGTTGAAAGAGT
ACATGCTGATAATAATGGTACTTTGATACCAATTTCTATAATTTATAAAAAGTCTAAGTTTAAGCGTGATGGTTCCAATC
CAATGTTTTTATATGGATATGGTTCATATGGCATATCTCTAAATCCTTCATTTAACAATAATATATTTTCATTAGTAGAT
CGTGGTATTGTTTATGCTCTAGCTCATATTAGGGGAGGAGATGATTTAGGATATAGTTGGTATACACAGGCTAAATTTTT
AACAAAAAAGAACACCTTTGAAGATTTTATCTGTTGTAGTAAATATTTAATTGAAAATAATTATACTAGCAAAGGTAATA
TTATAATTGGTGGAGGTAGTGCTGGAGGTTTATTAATAGGAACTGTTATTAATACTAATTCTGAACTGTATAAAGCAGCA
ATTTTACATGTGCCATTTGTAGATGTGTTAAATACTATGCTTGATTCTTCACTGCCACTGACTCCTGGGGAATATGATGA
ATGGGGTGATCCACGAAAACAAGAATATTTTGATTATATTAAATCATACTCACCTTATGACAATATAAAGGCTCAGCGTT
ATCCTCATATATATGTTACTGTTGGCTTAAGTGATTTAAGAGTTGGTTATTGGGAAGCAGCAAAATGGGTTGCTAAGTTG
CGTTCATTAAAAACTGATAGCAATAAGTTAATTTTTAAAACTAATATGAATTTAGGTCATAGTGGTCCTAGTGATCGTTT
TGCTTATTTAAAAGAACAAGCTCAAGATTATTGCTTTATTTTAAGTTTGCTAGCAGATTAG

Upstream 100 bases:

>100_bases
TCTAGGAAGATTAAACAGCTTGAAGATAAAATATAATCAGAAGATTATATTTTGTTCTGGTGTTTAATGTTAATTATTTT
GTTAATCATATTACACAGCG

Downstream 100 bases:

>100_bases
AAGATGCAATTTATTTAATATAAGATGGTAAGTTATAATAATTTTTTTGATAATCACTTACATAGCATAAAATTAGAAGG
AAGATATAGAAAATTTACTT

Product: protease II

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 686; Mature: 685

Protein sequence:

>686_residues
MSTSIAHPIAKKVPYSFTVNNNKISDDFAWLRDRKWPKQVKDKSILAYLEAENNYADAYFSKYQPMITEIYEELKSRIKL
TDQSAYTKKKNYFYYIRTEAEKAYQIFCRKYGSINAQEEIILDVNELAEHCSFVSVGTFSVSPDNNYVAYSVDYDGSERY
KIRVLDLKTNTYLADEITQVIGGIVWHEAICGFFYTKTNEYWRSDKVFFHKLNCNPEDDQLIFEEGNALYNLVIQKSSDD
KYLFIESSGHDNNEYYFVSTENTSLAPYIIQPRMPKVIYDVEHYNGEFFILTNDINENFRLVVTKVENPSQRYWKTFLEF
NENEYLKSFDISKSCLIITYKVNGLSAIKILNFINNEIKTLNFDEAAFSAIAYTSNFEEDDIRVEYSSLRQPKILYQYDL
VLGKLNILKKNEVLGNFNSEEYQVERVHADNNGTLIPISIIYKKSKFKRDGSNPMFLYGYGSYGISLNPSFNNNIFSLVD
RGIVYALAHIRGGDDLGYSWYTQAKFLTKKNTFEDFICCSKYLIENNYTSKGNIIIGGGSAGGLLIGTVINTNSELYKAA
ILHVPFVDVLNTMLDSSLPLTPGEYDEWGDPRKQEYFDYIKSYSPYDNIKAQRYPHIYVTVGLSDLRVGYWEAAKWVAKL
RSLKTDSNKLIFKTNMNLGHSGPSDRFAYLKEQAQDYCFILSLLAD

Sequences:

>Translated_686_residues
MSTSIAHPIAKKVPYSFTVNNNKISDDFAWLRDRKWPKQVKDKSILAYLEAENNYADAYFSKYQPMITEIYEELKSRIKL
TDQSAYTKKKNYFYYIRTEAEKAYQIFCRKYGSINAQEEIILDVNELAEHCSFVSVGTFSVSPDNNYVAYSVDYDGSERY
KIRVLDLKTNTYLADEITQVIGGIVWHEAICGFFYTKTNEYWRSDKVFFHKLNCNPEDDQLIFEEGNALYNLVIQKSSDD
KYLFIESSGHDNNEYYFVSTENTSLAPYIIQPRMPKVIYDVEHYNGEFFILTNDINENFRLVVTKVENPSQRYWKTFLEF
NENEYLKSFDISKSCLIITYKVNGLSAIKILNFINNEIKTLNFDEAAFSAIAYTSNFEEDDIRVEYSSLRQPKILYQYDL
VLGKLNILKKNEVLGNFNSEEYQVERVHADNNGTLIPISIIYKKSKFKRDGSNPMFLYGYGSYGISLNPSFNNNIFSLVD
RGIVYALAHIRGGDDLGYSWYTQAKFLTKKNTFEDFICCSKYLIENNYTSKGNIIIGGGSAGGLLIGTVINTNSELYKAA
ILHVPFVDVLNTMLDSSLPLTPGEYDEWGDPRKQEYFDYIKSYSPYDNIKAQRYPHIYVTVGLSDLRVGYWEAAKWVAKL
RSLKTDSNKLIFKTNMNLGHSGPSDRFAYLKEQAQDYCFILSLLAD
>Mature_685_residues
STSIAHPIAKKVPYSFTVNNNKISDDFAWLRDRKWPKQVKDKSILAYLEAENNYADAYFSKYQPMITEIYEELKSRIKLT
DQSAYTKKKNYFYYIRTEAEKAYQIFCRKYGSINAQEEIILDVNELAEHCSFVSVGTFSVSPDNNYVAYSVDYDGSERYK
IRVLDLKTNTYLADEITQVIGGIVWHEAICGFFYTKTNEYWRSDKVFFHKLNCNPEDDQLIFEEGNALYNLVIQKSSDDK
YLFIESSGHDNNEYYFVSTENTSLAPYIIQPRMPKVIYDVEHYNGEFFILTNDINENFRLVVTKVENPSQRYWKTFLEFN
ENEYLKSFDISKSCLIITYKVNGLSAIKILNFINNEIKTLNFDEAAFSAIAYTSNFEEDDIRVEYSSLRQPKILYQYDLV
LGKLNILKKNEVLGNFNSEEYQVERVHADNNGTLIPISIIYKKSKFKRDGSNPMFLYGYGSYGISLNPSFNNNIFSLVDR
GIVYALAHIRGGDDLGYSWYTQAKFLTKKNTFEDFICCSKYLIENNYTSKGNIIIGGGSAGGLLIGTVINTNSELYKAAI
LHVPFVDVLNTMLDSSLPLTPGEYDEWGDPRKQEYFDYIKSYSPYDNIKAQRYPHIYVTVGLSDLRVGYWEAAKWVAKLR
SLKTDSNKLIFKTNMNLGHSGPSDRFAYLKEQAQDYCFILSLLAD

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=713, Percent_Identity=24.6844319775596, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI284172420, Length=589, Percent_Identity=26.8251273344652, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI284172413, Length=589, Percent_Identity=26.8251273344652, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI70778815, Length=589, Percent_Identity=26.8251273344652, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI284172438, Length=585, Percent_Identity=27.008547008547, Blast_Score=194, Evalue=3e-49,
Organism=Homo sapiens, GI284172431, Length=585, Percent_Identity=27.008547008547, Blast_Score=194, Evalue=3e-49,
Organism=Homo sapiens, GI108860686, Length=256, Percent_Identity=35.9375, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI108860692, Length=218, Percent_Identity=36.697247706422, Blast_Score=142, Evalue=9e-34,
Organism=Escherichia coli, GI1788150, Length=691, Percent_Identity=35.4558610709117, Blast_Score=445, Evalue=1e-126,
Organism=Drosophila melanogaster, GI24583414, Length=733, Percent_Identity=25.5115961800819, Blast_Score=192, Evalue=6e-49,
Organism=Drosophila melanogaster, GI221510989, Length=707, Percent_Identity=24.8939179632249, Blast_Score=183, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 79358; Mature: 79227

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSIAHPIAKKVPYSFTVNNNKISDDFAWLRDRKWPKQVKDKSILAYLEAENNYADAYF
CCCCCCCHHHHHCCEEEEECCCCCCCHHHHHHCCCCCHHHCCCEEEEEEECCCCCCHHHH
SKYQPMITEIYEELKSRIKLTDQSAYTKKKNYFYYIRTEAEKAYQIFCRKYGSINAQEEI
HHCCHHHHHHHHHHHHHEEECCCHHHCCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCEE
ILDVNELAEHCSFVSVGTFSVSPDNNYVAYSVDYDGSERYKIRVLDLKTNTYLADEITQV
EEEHHHHHHHCCEEEEEEEEECCCCCEEEEEEECCCCCEEEEEEEEEECCCCHHHHHHHH
IGGIVWHEAICGFFYTKTNEYWRSDKVFFHKLNCNPEDDQLIFEEGNALYNLVIQKSSDD
HHHHHHHHHHHHEEEECCCCCCCCCCEEEEEECCCCCCCEEEEECCCEEEEEEEEECCCC
KYLFIESSGHDNNEYYFVSTENTSLAPYIIQPRMPKVIYDVEHYNGEFFILTNDINENFR
CEEEEECCCCCCCEEEEEECCCCCCCCEEECCCCCEEEEEEEECCCEEEEEECCCCCCEE
LVVTKVENPSQRYWKTFLEFNENEYLKSFDISKSCLIITYKVNGLSAIKILNFINNEIKT
EEEEECCCCHHHHHHHHHHCCCCCCEEECCCCCCEEEEEEEECCCCHHHHHHHHCCCCEE
LNFDEAAFSAIAYTSNFEEDDIRVEYSSLRQPKILYQYDLVLGKLNILKKNEVLGNFNSE
EECCHHHHHEEEECCCCCCCCEEEEHHHCCCCEEEEEEEEEEEEEEEEECCCCCCCCCCC
EYQVERVHADNNGTLIPISIIYKKSKFKRDGSNPMFLYGYGSYGISLNPSFNNNIFSLVD
CEEEEEEEECCCCCEEEEEEEEECCCCCCCCCCCEEEEEECCCCEEECCCCCCCHHHHHH
RGIVYALAHIRGGDDLGYSWYTQAKFLTKKNTFEDFICCSKYLIENNYTSKGNIIIGGGS
HHHHEEEEHCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCEEEECCC
AGGLLIGTVINTNSELYKAAILHVPFVDVLNTMLDSSLPLTPGEYDEWGDPRKQEYFDYI
CCCEEEEEEECCCCHHEEEHHEECCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
KSYSPYDNIKAQRYPHIYVTVGLSDLRVGYWEAAKWVAKLRSLKTDSNKLIFKTNMNLGH
HCCCCCCCCCCCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
SGPSDRFAYLKEQAQDYCFILSLLAD
CCCCHHHHHHHHHHHHHEEHHHHHCC
>Mature Secondary Structure 
STSIAHPIAKKVPYSFTVNNNKISDDFAWLRDRKWPKQVKDKSILAYLEAENNYADAYF
CCCCCCHHHHHCCEEEEECCCCCCCHHHHHHCCCCCHHHCCCEEEEEEECCCCCCHHHH
SKYQPMITEIYEELKSRIKLTDQSAYTKKKNYFYYIRTEAEKAYQIFCRKYGSINAQEEI
HHCCHHHHHHHHHHHHHEEECCCHHHCCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCEE
ILDVNELAEHCSFVSVGTFSVSPDNNYVAYSVDYDGSERYKIRVLDLKTNTYLADEITQV
EEEHHHHHHHCCEEEEEEEEECCCCCEEEEEEECCCCCEEEEEEEEEECCCCHHHHHHHH
IGGIVWHEAICGFFYTKTNEYWRSDKVFFHKLNCNPEDDQLIFEEGNALYNLVIQKSSDD
HHHHHHHHHHHHEEEECCCCCCCCCCEEEEEECCCCCCCEEEEECCCEEEEEEEEECCCC
KYLFIESSGHDNNEYYFVSTENTSLAPYIIQPRMPKVIYDVEHYNGEFFILTNDINENFR
CEEEEECCCCCCCEEEEEECCCCCCCCEEECCCCCEEEEEEEECCCEEEEEECCCCCCEE
LVVTKVENPSQRYWKTFLEFNENEYLKSFDISKSCLIITYKVNGLSAIKILNFINNEIKT
EEEEECCCCHHHHHHHHHHCCCCCCEEECCCCCCEEEEEEEECCCCHHHHHHHHCCCCEE
LNFDEAAFSAIAYTSNFEEDDIRVEYSSLRQPKILYQYDLVLGKLNILKKNEVLGNFNSE
EECCHHHHHEEEECCCCCCCCEEEEHHHCCCCEEEEEEEEEEEEEEEEECCCCCCCCCCC
EYQVERVHADNNGTLIPISIIYKKSKFKRDGSNPMFLYGYGSYGISLNPSFNNNIFSLVD
CEEEEEEEECCCCCEEEEEEEEECCCCCCCCCCCEEEEEECCCCEEECCCCCCCHHHHHH
RGIVYALAHIRGGDDLGYSWYTQAKFLTKKNTFEDFICCSKYLIENNYTSKGNIIIGGGS
HHHHEEEEHCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCEEEECCC
AGGLLIGTVINTNSELYKAAILHVPFVDVLNTMLDSSLPLTPGEYDEWGDPRKQEYFDYI
CCCEEEEEEECCCCHHEEEHHEECCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
KSYSPYDNIKAQRYPHIYVTVGLSDLRVGYWEAAKWVAKLRSLKTDSNKLIFKTNMNLGH
HCCCCCCCCCCCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
SGPSDRFAYLKEQAQDYCFILSLLAD
CCCCHHHHHHHHHHHHHEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7629037 [H]