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The map label for this gene is rsh [H]

Identifier: 189183898

GI number: 189183898

Start: 1038229

End: 1038633

Strand: Direct

Name: rsh [H]

Synonym: OTT_0991

Alternate gene names: 189183898

Gene position: 1038229-1038633 (Clockwise)

Preceding gene: 189183897

Following gene: 189183899

Centisome position: 51.68

GC content: 31.6

Gene sequence:

>405_bases
ATGGAGGAAATAATGTTGGCATTTTTAAATTGTGAACATATCAATAAACTACTTGATAAGCTGGACTTGATTAATCATAG
TTTTGATAAATGCATTAATCTTGATAAAGTTAAAAAAGCTATATTTTATGTAAAAAAATATCATGGCAATCAAAAGCGAG
ATACAGGAGAACCTTATTATATGCATCCATTAGAAGTAGCGCTCATGGTTGCAGACTACAGCTTTAAAACGGATACGATT
ATTACAGCAATACTACATGATACCATCGAAGACACAACGCTAACTAAAGAAAAGATAGCAATCGAATTTAATGATAACAT
TGCCGAGCAAGTTCTAGCTCTTACAAGAAACAGAGGTGGTAAGAAAACCAGTTCCATGAAAATGATTCAAACATTAGTGA
ATTAA

Upstream 100 bases:

>100_bases
AAATTAAACTAGAAAGTAACCAAGATCAGTATACAGCTTTCACATGTAGTATACCTATCGAAGTTCGTTGAGAAACTGAC
AATTAGAATTATTAATAGAG

Downstream 100 bases:

>100_bases
GATAAAGTAGAGCTATTACTAATCAAACTATTGGACAGATTGGATAATATTAAAACTATATTCATAAAGCCAGACAAAAG
AAGACAAGAAATCATACTAG

Product: RelA/SpoT-related protein

Products: NA

Alternate protein names: (p)ppGpp synthase; ATP:GTP 3'-pyrophosphotransferase [H]

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MEEIMLAFLNCEHINKLLDKLDLINHSFDKCINLDKVKKAIFYVKKYHGNQKRDTGEPYYMHPLEVALMVADYSFKTDTI
ITAILHDTIEDTTLTKEKIAIEFNDNIAEQVLALTRNRGGKKTSSMKMIQTLVN

Sequences:

>Translated_134_residues
MEEIMLAFLNCEHINKLLDKLDLINHSFDKCINLDKVKKAIFYVKKYHGNQKRDTGEPYYMHPLEVALMVADYSFKTDTI
ITAILHDTIEDTTLTKEKIAIEFNDNIAEQVLALTRNRGGKKTSSMKMIQTLVN
>Mature_134_residues
MEEIMLAFLNCEHINKLLDKLDLINHSFDKCINLDKVKKAIFYVKKYHGNQKRDTGEPYYMHPLEVALMVADYSFKTDTI
ITAILHDTIEDTTLTKEKIAIEFNDNIAEQVLALTRNRGGKKTSSMKMIQTLVN

Specific function: Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. Plays a role in ada

COG id: COG0317

COG function: function code TK; Guanosine polyphosphate pyrophosphohydrolases/synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HD domain [H]

Homologues:

Organism=Escherichia coli, GI1790082, Length=100, Percent_Identity=29, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR012675
- InterPro:   IPR003607
- InterPro:   IPR007685
- InterPro:   IPR004811
- InterPro:   IPR004095
- InterPro:   IPR012676 [H]

Pfam domain/function: PF01842 ACT; PF04607 RelA_SpoT; PF02824 TGS [H]

EC number: =2.7.6.5 [H]

Molecular weight: Translated: 15466; Mature: 15466

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEIMLAFLNCEHINKLLDKLDLINHSFDKCINLDKVKKAIFYVKKYHGNQKRDTGEPYY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCEE
MHPLEVALMVADYSFKTDTIITAILHDTIEDTTLTKEKIAIEFNDNIAEQVLALTRNRGG
ECHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHEEEEECCCHHHHHHHHHHCCCC
KKTSSMKMIQTLVN
CCHHHHHHHHHHHC
>Mature Secondary Structure
MEEIMLAFLNCEHINKLLDKLDLINHSFDKCINLDKVKKAIFYVKKYHGNQKRDTGEPYY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCEE
MHPLEVALMVADYSFKTDTIITAILHDTIEDTTLTKEKIAIEFNDNIAEQVLALTRNRGG
ECHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHEEEEECCCHHHHHHHHHHCCCC
KKTSSMKMIQTLVN
CCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA