Click here to switch to the map view.

The map label for this gene is infC [H]

Identifier: 189183872

GI number: 189183872

Start: 1012861

End: 1013364

Strand: Direct

Name: infC [H]

Synonym: OTT_0965

Alternate gene names: 189183872

Gene position: 1012861-1013364 (Clockwise)

Preceding gene: 189183871

Following gene: 189183873

Centisome position: 50.42

GC content: 32.14

Gene sequence:

>504_bases
TTGAAGGTAAATGGCGAAATTAAGGCTAAGCAAGTTAGGCTAATTGATGAAAGTGGCAATATGATTGGTATAACATCATT
GTCAGAAGCTATTAGTAAAGCAGAGATGGCAGGATTAGATTTAGTTGAGTTTTCACAATCAGATTTGCCATTATGTAAAA
TCTTAGACTATAGTAAGTACAAATACGAAATTAAAAAAAAGGCTCAGCAAGCAAAAAAGAAGCAAACGAAAGTTACTGTA
AAAGAAATTAAGTTGCGTCCTAACATTGCTGATGGGGATCTTGCGATTAAGATAAAAAGTATCAAGCAATTTTTAAGCAA
AAATAATAAGGTTAACATAAGTGTAATATTTAAGGGCAGAGAAATAGTACATGCTGAATTTGGGAGACAAATACTTGATA
ATATTATTGATGTATGCCAAGTAGAAGGAAAAATTGACTCTCCACCTAAAATGCAGGGGCAGGTTATTACAATGACTATG
TCACCTAATATTATTAAAACCTAG

Upstream 100 bases:

>100_bases
ATAAGTAGTAGTGAATTAATTGCTCATATAAGAAAAAACAAAAAATAAGATTAACTAATTGAGGAGAAGTTTTATTTCCA
CAAATAAAAGTAGCGGCTAT

Downstream 100 bases:

>100_bases
GATTTGATTTAATTAAAAAAAGCGATTGATTCAATCATCTGATTTGCTATTTATATCTAATGTTTTTGCTCTCTATAGTT
TGACATATTTTTTATATTGA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MKVNGEIKAKQVRLIDESGNMIGITSLSEAISKAEMAGLDLVEFSQSDLPLCKILDYSKYKYEIKKKAQQAKKKQTKVTV
KEIKLRPNIADGDLAIKIKSIKQFLSKNNKVNISVIFKGREIVHAEFGRQILDNIIDVCQVEGKIDSPPKMQGQVITMTM
SPNIIKT

Sequences:

>Translated_167_residues
MKVNGEIKAKQVRLIDESGNMIGITSLSEAISKAEMAGLDLVEFSQSDLPLCKILDYSKYKYEIKKKAQQAKKKQTKVTV
KEIKLRPNIADGDLAIKIKSIKQFLSKNNKVNISVIFKGREIVHAEFGRQILDNIIDVCQVEGKIDSPPKMQGQVITMTM
SPNIIKT
>Mature_167_residues
MKVNGEIKAKQVRLIDESGNMIGITSLSEAISKAEMAGLDLVEFSQSDLPLCKILDYSKYKYEIKKKAQQAKKKQTKVTV
KEIKLRPNIADGDLAIKIKSIKQFLSKNNKVNISVIFKGREIVHAEFGRQILDNIIDVCQVEGKIDSPPKMQGQVITMTM
SPNIIKT

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=163, Percent_Identity=41.7177914110429, Blast_Score=128, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 18692; Mature: 18692

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVNGEIKAKQVRLIDESGNMIGITSLSEAISKAEMAGLDLVEFSQSDLPLCKILDYSKY
CCCCCCEEEEEEEEEECCCCEEEEHHHHHHHHHHHHCCCCEEECCCCCCCCEEEECCCHH
KYEIKKKAQQAKKKQTKVTVKEIKLRPNIADGDLAIKIKSIKQFLSKNNKVNISVIFKGR
HHHHHHHHHHHHHHHHHEEEEHEEECCCCCCCCEEEEEHHHHHHHHCCCEEEEEEEECCC
EIVHAEFGRQILDNIIDVCQVEGKIDSPPKMQGQVITMTMSPNIIKT
EEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCEECC
>Mature Secondary Structure
MKVNGEIKAKQVRLIDESGNMIGITSLSEAISKAEMAGLDLVEFSQSDLPLCKILDYSKY
CCCCCCEEEEEEEEEECCCCEEEEHHHHHHHHHHHHCCCCEEECCCCCCCCEEEECCCHH
KYEIKKKAQQAKKKQTKVTVKEIKLRPNIADGDLAIKIKSIKQFLSKNNKVNISVIFKGR
HHHHHHHHHHHHHHHHHEEEEHEEECCCCCCCCEEEEEHHHHHHHHCCCEEEEEEEECCC
EIVHAEFGRQILDNIIDVCQVEGKIDSPPKMQGQVITMTMSPNIIKT
EEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]