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The map label for this gene is 189183852

Identifier: 189183852

GI number: 189183852

Start: 988517

End: 990067

Strand: Direct

Name: 189183852

Synonym: OTT_0945

Alternate gene names: NA

Gene position: 988517-990067 (Clockwise)

Preceding gene: 189183843

Following gene: 189183853

Centisome position: 49.2

GC content: 40.75

Gene sequence:

>1551_bases
ATGAAAAAAATTATGTTAATTGCTAGTGCAATGTCTGCGTTGTCGTTGCCGTTTTTAGCTAGTGCGATAGAATTGGGGGA
TGAAGGAGGATTAGAGTGTGGTCCTTATGCTAAAGTTGGAGTCGTTGGAGGAATGATTACTGGCGTAGAATCTACTCGCT
TGGATTCAGCTGATGCTGATGGCAAAAAACACTTGTCATTAATAACTGGGATACCATTTGGTGGTACATTAGCTGCAGGT
ATGACAATTGCGCCAGGATTTAGAGCAGAGCTAGGGGTTATGTACCTTAGAAATATAAGCGCTGAGGTTGAAGTAGGTAA
AGGCAAGGTAGATTCTAGAGGTGAGGTAAAGGCAGATTCTGGATGTGGAATAGATGCTCCTATACGTAAGCGGCCTAAAC
TTACACCACCTCAGCCTACTATAATGCCTATAAGTATAGCTGATCGTGATGTGGGGGTTGATACTGATATTCTTCCTCAA
GCTGCTGCTGGGCAACCACAGCTTACTGTTGAGCAGCGGGCTGTACGTAGAATTGCGTGGTTGAAGGATTATGCTGGTAT
TGACTATATGGTTCCAGATCCTCAGAATCCTAATGCTAGAGTTGTAAATCCTGTATTGTTAAATATTACTCAAGGACCAC
CTAACGTACAGCCTAGACCTCGGCAAGATCTTAACATACTTGACCATGATCAGTGGAGGCATTTGGTAGTTGGTGTTACT
GCATTGTCACATGCTAATAAACCTAGCGTTACTCCCGTCAAAGTATTAAGTGACAAAATTACTAAGATATATAGTGATAT
AAGACAATTCGCTAAGGTAGCTAATATTGAAGTTCCTGATGCTCCTTTGCCTAATAGTGCATCTGTTGAACAGATACAGG
CTAAAATGCAAGAATTAAATAATGTCTTGGAAGAGCTCAGAGAGTCTTTTGATGGGTATCTTGCTAATGCTTTTGTTAAT
CAGATTCAGTTAAATTTCCAGATTCAGCAAGCGCAGCCACAGCAGCAAGGACAGCCACAGCAGCAAGGACAAGTTACAGC
TCAAGAAGCAGCAGCAGCTGCAGCTGTTAGGGCTTTAAATGGTAATGAACAGATTATACAGTTATATAAAGATCTTGTTA
AATTGCAGCGTCATGCAGGAATTAGGAAGGCTATGGAACAATTGGCTGCCCAAGAAGAAGGCGATGATCAAAATCAAGGA
AGTTGCAAGGATAAGAAGCAGCAAGAAGTATCTAAAAAAGAAACAGAGTTTGATCTGAGTATGATTGTCGGCCAAGTTAA
ACTCTATGCTGACTTATTTACAACTGAATCATTCTCAATATATGCTGGTCTTGGTGCAGGGGTAGCTTATACTTCTGGAA
AAATAGATGGTGTGGATATTAAAGCTAATACTGGTATGGTTGCATCAGGGGCACTTGGTGTAGCAATTAATGCTGCTGAG
GGTGTGTATGTGGACATAGAAGGTAGTTATATGTACTCATTCAGTAAAATAGAAGAGAAGTATTCAATAAATCCTCTTAT
GGCAAGTGTAGGTGTACGCTATAACTTCTAG

Upstream 100 bases:

>100_bases
ATAATAGTTTTTTGATATAAAACTAAGTTAGTGTGGCTAAATAATTAGTTTAGAATGGTTACCACTAAAAAATAAATTTA
ATTCTTTTAAGGAGATTAGA

Downstream 100 bases:

>100_bases
TTTTTCTTTAAAATTATAAAAAAGCAGCTAAAAGTCCTTTGAAGGGTTTTTAGCTACTTTTTCAGAGTTTTTTTATAATA
ATAAAAATTAACTTTATTCT

Product: 56 kDa type-specific antigen

Products: NA

Alternate protein names: TSA; 56 kDa scrub typhus antigen; STA56; TSG56 [H]

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MKKIMLIASAMSALSLPFLASAIELGDEGGLECGPYAKVGVVGGMITGVESTRLDSADADGKKHLSLITGIPFGGTLAAG
MTIAPGFRAELGVMYLRNISAEVEVGKGKVDSRGEVKADSGCGIDAPIRKRPKLTPPQPTIMPISIADRDVGVDTDILPQ
AAAGQPQLTVEQRAVRRIAWLKDYAGIDYMVPDPQNPNARVVNPVLLNITQGPPNVQPRPRQDLNILDHDQWRHLVVGVT
ALSHANKPSVTPVKVLSDKITKIYSDIRQFAKVANIEVPDAPLPNSASVEQIQAKMQELNNVLEELRESFDGYLANAFVN
QIQLNFQIQQAQPQQQGQPQQQGQVTAQEAAAAAAVRALNGNEQIIQLYKDLVKLQRHAGIRKAMEQLAAQEEGDDQNQG
SCKDKKQQEVSKKETEFDLSMIVGQVKLYADLFTTESFSIYAGLGAGVAYTSGKIDGVDIKANTGMVASGALGVAINAAE
GVYVDIEGSYMYSFSKIEEKYSINPLMASVGVRYNF

Sequences:

>Translated_516_residues
MKKIMLIASAMSALSLPFLASAIELGDEGGLECGPYAKVGVVGGMITGVESTRLDSADADGKKHLSLITGIPFGGTLAAG
MTIAPGFRAELGVMYLRNISAEVEVGKGKVDSRGEVKADSGCGIDAPIRKRPKLTPPQPTIMPISIADRDVGVDTDILPQ
AAAGQPQLTVEQRAVRRIAWLKDYAGIDYMVPDPQNPNARVVNPVLLNITQGPPNVQPRPRQDLNILDHDQWRHLVVGVT
ALSHANKPSVTPVKVLSDKITKIYSDIRQFAKVANIEVPDAPLPNSASVEQIQAKMQELNNVLEELRESFDGYLANAFVN
QIQLNFQIQQAQPQQQGQPQQQGQVTAQEAAAAAAVRALNGNEQIIQLYKDLVKLQRHAGIRKAMEQLAAQEEGDDQNQG
SCKDKKQQEVSKKETEFDLSMIVGQVKLYADLFTTESFSIYAGLGAGVAYTSGKIDGVDIKANTGMVASGALGVAINAAE
GVYVDIEGSYMYSFSKIEEKYSINPLMASVGVRYNF
>Mature_516_residues
MKKIMLIASAMSALSLPFLASAIELGDEGGLECGPYAKVGVVGGMITGVESTRLDSADADGKKHLSLITGIPFGGTLAAG
MTIAPGFRAELGVMYLRNISAEVEVGKGKVDSRGEVKADSGCGIDAPIRKRPKLTPPQPTIMPISIADRDVGVDTDILPQ
AAAGQPQLTVEQRAVRRIAWLKDYAGIDYMVPDPQNPNARVVNPVLLNITQGPPNVQPRPRQDLNILDHDQWRHLVVGVT
ALSHANKPSVTPVKVLSDKITKIYSDIRQFAKVANIEVPDAPLPNSASVEQIQAKMQELNNVLEELRESFDGYLANAFVN
QIQLNFQIQQAQPQQQGQPQQQGQVTAQEAAAAAAVRALNGNEQIIQLYKDLVKLQRHAGIRKAMEQLAAQEEGDDQNQG
SCKDKKQQEVSKKETEFDLSMIVGQVKLYADLFTTESFSIYAGLGAGVAYTSGKIDGVDIKANTGMVASGALGVAINAAE
GVYVDIEGSYMYSFSKIEEKYSINPLMASVGVRYNF

Specific function: May be an adherent factor for rickettsial adsorption to the host-cell surface and a determinant of virulence of individual rickettsial strain. It is the major outer membrane protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR004933 [H]

Pfam domain/function: PF03249 TSA [H]

EC number: NA

Molecular weight: Translated: 55587; Mature: 55587

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIMLIASAMSALSLPFLASAIELGDEGGLECGPYAKVGVVGGMITGVESTRLDSADAD
CCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHCCCCCCCC
GKKHLSLITGIPFGGTLAAGMTIAPGFRAELGVMYLRNISAEVEVGKGKVDSRGEVKADS
CHHHEEEEECCCCCCHHHCCCEECCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCEECCC
GCGIDAPIRKRPKLTPPQPTIMPISIADRDVGVDTDILPQAAAGQPQLTVEQRAVRRIAW
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LKDYAGIDYMVPDPQNPNARVVNPVLLNITQGPPNVQPRPRQDLNILDHDQWRHLVVGVT
HHHHCCCCEECCCCCCCCCEEECEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ALSHANKPSVTPVKVLSDKITKIYSDIRQFAKVANIEVPDAPLPNSASVEQIQAKMQELN
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
NVLEELRESFDGYLANAFVNQIQLNFQIQQAQPQQQGQPQQQGQVTAQEAAAAAAVRALN
HHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCHHCCCCHHHCCCHHHHHHHHHHHHHCC
GNEQIIQLYKDLVKLQRHAGIRKAMEQLAAQEEGDDQNQGSCKDKKQQEVSKKETEFDLS
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
MIVGQVKLYADLFTTESFSIYAGLGAGVAYTSGKIDGVDIKANTGMVASGALGVAINAAE
HHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCEEEECCCCEEECCCCEEEEECCC
GVYVDIEGSYMYSFSKIEEKYSINPLMASVGVRYNF
CEEEEECCCEEEEHHHHHHHHCCCHHHHHCCCEECC
>Mature Secondary Structure
MKKIMLIASAMSALSLPFLASAIELGDEGGLECGPYAKVGVVGGMITGVESTRLDSADAD
CCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHCCCCCCCC
GKKHLSLITGIPFGGTLAAGMTIAPGFRAELGVMYLRNISAEVEVGKGKVDSRGEVKADS
CHHHEEEEECCCCCCHHHCCCEECCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCEECCC
GCGIDAPIRKRPKLTPPQPTIMPISIADRDVGVDTDILPQAAAGQPQLTVEQRAVRRIAW
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LKDYAGIDYMVPDPQNPNARVVNPVLLNITQGPPNVQPRPRQDLNILDHDQWRHLVVGVT
HHHHCCCCEECCCCCCCCCEEECEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ALSHANKPSVTPVKVLSDKITKIYSDIRQFAKVANIEVPDAPLPNSASVEQIQAKMQELN
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
NVLEELRESFDGYLANAFVNQIQLNFQIQQAQPQQQGQPQQQGQVTAQEAAAAAAVRALN
HHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCHHCCCCHHHCCCHHHHHHHHHHHHHCC
GNEQIIQLYKDLVKLQRHAGIRKAMEQLAAQEEGDDQNQGSCKDKKQQEVSKKETEFDLS
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
MIVGQVKLYADLFTTESFSIYAGLGAGVAYTSGKIDGVDIKANTGMVASGALGVAINAAE
HHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCEEEECCCCEEECCCCEEEEECCC
GVYVDIEGSYMYSFSKIEEKYSINPLMASVGVRYNF
CEEEEECCCEEEEHHHHHHHHCCCHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2401407; 2496028 [H]