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The map label for this gene is htpG [H]

Identifier: 189183698

GI number: 189183698

Start: 832488

End: 834380

Strand: Direct

Name: htpG [H]

Synonym: OTT_0791

Alternate gene names: 189183698

Gene position: 832488-834380 (Clockwise)

Preceding gene: 189183695

Following gene: 189183699

Centisome position: 41.44

GC content: 29.79

Gene sequence:

>1893_bases
ATGTCAGTAGAAACTTATAAATTTGATGCAGAAGTAGGCAAAGTACTTCATTTGGTAATTCACACATTATATACCAATAA
GAAGATTTTTTTACGAGAATTAATTTCAAATGCCTCTGATGCTTGTGATAAGCTACGTTATCTTAGTCAAAGTAATGCTG
AACTGCAGCAAGGAGAAAGTGATTTTAAAATTACTGTCTCAATGGATAAGGAAAAACGTTATATAATTTTACAAGATAAC
GGTATTGGAATGAATAAAGAAGACCTAACACAGAATTTAGGAACGATAGCTAGTTCTGGCACTCAAAAATTTTTGGAGCA
GTTAGGCAATGATGCTAAAAAGGATAACATGTTGATAGGGCAATTTGGAGTGGGGTTTTATTCATCATATATGGTAGCAG
ATGAGGTTAAAGTAATATCTAAGAAGGCTGGTGAAGCACAAGCTTATCAGTGGTCTTCTAAAGGTGAAGGTGAGTATTAT
ATTGAAGATTGTGAAGCTGATTTTATTAGAGGTACAAAAATTACTTTACATATTAAACCAGAATATGATAACTACTTAGA
TCATTTTCAAATTAAAGATATTATTAAAACTTACTCTGATCATATCTCAGTTCCAATATATTATGTTGGAGTGGATGGTA
AGGAGCAACAAGTTAACTCATCATCAGCATTATGGACTAGAGCTAAAAGCGACATAACTGATGAACAATATGAGGAATTT
TATCGTAACATTGCATATGCTATAGATAAGCCGTGGATTACTATTCATAACAAATCTGAAGGAGTAATAGAATTTACAAA
CTTATTATTTATTCCTTCATCCAAAACTTTTGATTTATTTCATCCTGATAGAAAAAGCCGAGTAAAACTTTATATAAAGA
AGGTATTTATTACTGATGAGAATGTTGCTTTAATTCCAAAATATATGAGATTTTTAAGAGGAGTAGTAGATTCAGAAGAT
TTACCGTTAAATATCAGCCGTGAAACCTTACAACATAGTCCTTTGATTGACAAAATTCAGGCATCTATAACCAAAAAAGT
TATTACAGAACTAGAAAAGCAAAAAACTAAAGATCAAGGCGAATATGAAACATTTTGGAATAATTTTGGAGCAGTTCTAA
AAGAAGGATTATGTGAAGGTACAGCAGATGTTGATAAATTATTAAAAATCTGTTTGTTTAGAAGTGCATTACAAGATAAG
TTTATTTCACTTGATGAATATATTGCTAATTTAAAATCAGAACAAAAAAACATTTATTATATTACTGGAGATGATTTAGA
AGCTCTTAAATCTAGTCCGCAAATTGAAGGTTTATTAAGTAGAAATATTGATGTTTTACTACTTACCGACGATGTTGATA
AGTTCTGGGTTATGGTGACTAGAAAGTATAATGACTATGTATTGAAGTCAGTAACTTCAGCTAATATTGAAATTGACAAT
TGTGATACTAAAACAGCTGAATCAAGTGATACCAATAACGATGCTAAAGATGATACTTCATCTTCTGATGACAAAAATTG
TGAGCAATTAATCAAATATTTTAAAGAAGTATTAGGAGATAAAGTTAAATCAGTGGAAGTATCTAAAAAACTCACTCGCA
GTCCAGTATGTTTAACAGTACCAGAAGGAAGTATGGATATTAGGACTGAAAGGTTTTTAATAGAGCAAAAGCAATTAAGT
AGCCATTCTAGCAAAATTTTGGAAATTAATCCTAATCACACAATTATTAAAAAGATTAATGAAAATATTAAGCTTAATCA
AAATTTAGATGTAAATAAACAGCTTGTAATGACTTTATTGGATCAATCTTACTTGATAGAGGGACAACCGATTCCTGATC
TACAAGATTATTGTAATCGTATAAATTTCTTTATTGAAAAATCAGTAAATTAA

Upstream 100 bases:

>100_bases
ATCTGAAGATATAGCAGCTATATTGCTACTATATCTTGAACTGTCTAAATTTTGTATACAAAATGTAATATTGTTTAATT
CACTAAAAAATAGTTAGAAA

Downstream 100 bases:

>100_bases
GTCTTAAAGCGTTAATCTTTCAATTATCTTTATAACATTTTGTTATAAGTTTTTGATTGATGAAGCGCTTATACTAACAT
AATGTTGCTGAAAAACAACT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 630; Mature: 629

Protein sequence:

>630_residues
MSVETYKFDAEVGKVLHLVIHTLYTNKKIFLRELISNASDACDKLRYLSQSNAELQQGESDFKITVSMDKEKRYIILQDN
GIGMNKEDLTQNLGTIASSGTQKFLEQLGNDAKKDNMLIGQFGVGFYSSYMVADEVKVISKKAGEAQAYQWSSKGEGEYY
IEDCEADFIRGTKITLHIKPEYDNYLDHFQIKDIIKTYSDHISVPIYYVGVDGKEQQVNSSSALWTRAKSDITDEQYEEF
YRNIAYAIDKPWITIHNKSEGVIEFTNLLFIPSSKTFDLFHPDRKSRVKLYIKKVFITDENVALIPKYMRFLRGVVDSED
LPLNISRETLQHSPLIDKIQASITKKVITELEKQKTKDQGEYETFWNNFGAVLKEGLCEGTADVDKLLKICLFRSALQDK
FISLDEYIANLKSEQKNIYYITGDDLEALKSSPQIEGLLSRNIDVLLLTDDVDKFWVMVTRKYNDYVLKSVTSANIEIDN
CDTKTAESSDTNNDAKDDTSSSDDKNCEQLIKYFKEVLGDKVKSVEVSKKLTRSPVCLTVPEGSMDIRTERFLIEQKQLS
SHSSKILEINPNHTIIKKINENIKLNQNLDVNKQLVMTLLDQSYLIEGQPIPDLQDYCNRINFFIEKSVN

Sequences:

>Translated_630_residues
MSVETYKFDAEVGKVLHLVIHTLYTNKKIFLRELISNASDACDKLRYLSQSNAELQQGESDFKITVSMDKEKRYIILQDN
GIGMNKEDLTQNLGTIASSGTQKFLEQLGNDAKKDNMLIGQFGVGFYSSYMVADEVKVISKKAGEAQAYQWSSKGEGEYY
IEDCEADFIRGTKITLHIKPEYDNYLDHFQIKDIIKTYSDHISVPIYYVGVDGKEQQVNSSSALWTRAKSDITDEQYEEF
YRNIAYAIDKPWITIHNKSEGVIEFTNLLFIPSSKTFDLFHPDRKSRVKLYIKKVFITDENVALIPKYMRFLRGVVDSED
LPLNISRETLQHSPLIDKIQASITKKVITELEKQKTKDQGEYETFWNNFGAVLKEGLCEGTADVDKLLKICLFRSALQDK
FISLDEYIANLKSEQKNIYYITGDDLEALKSSPQIEGLLSRNIDVLLLTDDVDKFWVMVTRKYNDYVLKSVTSANIEIDN
CDTKTAESSDTNNDAKDDTSSSDDKNCEQLIKYFKEVLGDKVKSVEVSKKLTRSPVCLTVPEGSMDIRTERFLIEQKQLS
SHSSKILEINPNHTIIKKINENIKLNQNLDVNKQLVMTLLDQSYLIEGQPIPDLQDYCNRINFFIEKSVN
>Mature_629_residues
SVETYKFDAEVGKVLHLVIHTLYTNKKIFLRELISNASDACDKLRYLSQSNAELQQGESDFKITVSMDKEKRYIILQDNG
IGMNKEDLTQNLGTIASSGTQKFLEQLGNDAKKDNMLIGQFGVGFYSSYMVADEVKVISKKAGEAQAYQWSSKGEGEYYI
EDCEADFIRGTKITLHIKPEYDNYLDHFQIKDIIKTYSDHISVPIYYVGVDGKEQQVNSSSALWTRAKSDITDEQYEEFY
RNIAYAIDKPWITIHNKSEGVIEFTNLLFIPSSKTFDLFHPDRKSRVKLYIKKVFITDENVALIPKYMRFLRGVVDSEDL
PLNISRETLQHSPLIDKIQASITKKVITELEKQKTKDQGEYETFWNNFGAVLKEGLCEGTADVDKLLKICLFRSALQDKF
ISLDEYIANLKSEQKNIYYITGDDLEALKSSPQIEGLLSRNIDVLLLTDDVDKFWVMVTRKYNDYVLKSVTSANIEIDNC
DTKTAESSDTNNDAKDDTSSSDDKNCEQLIKYFKEVLGDKVKSVEVSKKLTRSPVCLTVPEGSMDIRTERFLIEQKQLSS
HSSKILEINPNHTIIKKINENIKLNQNLDVNKQLVMTLLDQSYLIEGQPIPDLQDYCNRINFFIEKSVN

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=644, Percent_Identity=34.472049689441, Blast_Score=360, Evalue=2e-99,
Organism=Homo sapiens, GI4507677, Length=427, Percent_Identity=30.4449648711944, Blast_Score=213, Evalue=4e-55,
Organism=Homo sapiens, GI20149594, Length=416, Percent_Identity=32.9326923076923, Blast_Score=213, Evalue=4e-55,
Organism=Homo sapiens, GI154146191, Length=416, Percent_Identity=32.6923076923077, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI153792590, Length=416, Percent_Identity=32.6923076923077, Blast_Score=210, Evalue=4e-54,
Organism=Escherichia coli, GI1786679, Length=631, Percent_Identity=39.9366085578447, Blast_Score=481, Evalue=1e-137,
Organism=Caenorhabditis elegans, GI17559162, Length=672, Percent_Identity=34.2261904761905, Blast_Score=373, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17542208, Length=681, Percent_Identity=29.9559471365639, Blast_Score=327, Evalue=1e-89,
Organism=Caenorhabditis elegans, GI115535205, Length=646, Percent_Identity=31.733746130031, Blast_Score=299, Evalue=4e-81,
Organism=Caenorhabditis elegans, GI115535167, Length=425, Percent_Identity=36.2352941176471, Blast_Score=256, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6325016, Length=694, Percent_Identity=34.5821325648415, Blast_Score=375, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6323840, Length=690, Percent_Identity=34.2028985507246, Blast_Score=373, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24586016, Length=625, Percent_Identity=36, Blast_Score=349, Evalue=3e-96,
Organism=Drosophila melanogaster, GI21357739, Length=686, Percent_Identity=30.3206997084548, Blast_Score=334, Evalue=1e-91,
Organism=Drosophila melanogaster, GI17647529, Length=416, Percent_Identity=32.4519230769231, Blast_Score=221, Evalue=9e-58,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 72159; Mature: 72027

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVETYKFDAEVGKVLHLVIHTLYTNKKIFLRELISNASDACDKLRYLSQSNAELQQGES
CCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHCCCCHHHCCCC
DFKITVSMDKEKRYIILQDNGIGMNKEDLTQNLGTIASSGTQKFLEQLGNDAKKDNMLIG
CEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEE
QFGVGFYSSYMVADEVKVISKKAGEAQAYQWSSKGEGEYYIEDCEADFIRGTKITLHIKP
ECCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEECCCCHHCCCCEEEEEECC
EYDNYLDHFQIKDIIKTYSDHISVPIYYVGVDGKEQQVNSSSALWTRAKSDITDEQYEEF
CCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHCCCCHHHHHHCCCCCCHHHHHHH
YRNIAYAIDKPWITIHNKSEGVIEFTNLLFIPSSKTFDLFHPDRKSRVKLYIKKVFITDE
HHHHHHHCCCCEEEEECCCCCEEEEEEEEEECCCCEEECCCCCCHHHHEEEEEEEEEECC
NVALIPKYMRFLRGVVDSEDLPLNISRETLQHSPLIDKIQASITKKVITELEKQKTKDQG
CCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
EYETFWNNFGAVLKEGLCEGTADVDKLLKICLFRSALQDKFISLDEYIANLKSEQKNIYY
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
ITGDDLEALKSSPQIEGLLSRNIDVLLLTDDVDKFWVMVTRKYNDYVLKSVTSANIEIDN
EECCCHHHHHCCCCHHHHHHCCCEEEEEECCCCEEEEEEEECCCHHHHHHHCCCCEEEEC
CDTKTAESSDTNNDAKDDTSSSDDKNCEQLIKYFKEVLGDKVKSVEVSKKLTRSPVCLTV
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEE
PEGSMDIRTERFLIEQKQLSSHSSKILEINPNHTIIKKINENIKLNQNLDVNKQLVMTLL
CCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCCEEECCCCCCHHHHHHHHH
DQSYLIEGQPIPDLQDYCNRINFFIEKSVN
CCHHEECCCCCCCHHHHHHHHHHHEEECCC
>Mature Secondary Structure 
SVETYKFDAEVGKVLHLVIHTLYTNKKIFLRELISNASDACDKLRYLSQSNAELQQGES
CCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHCCCCHHHCCCC
DFKITVSMDKEKRYIILQDNGIGMNKEDLTQNLGTIASSGTQKFLEQLGNDAKKDNMLIG
CEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEE
QFGVGFYSSYMVADEVKVISKKAGEAQAYQWSSKGEGEYYIEDCEADFIRGTKITLHIKP
ECCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEECCCCHHCCCCEEEEEECC
EYDNYLDHFQIKDIIKTYSDHISVPIYYVGVDGKEQQVNSSSALWTRAKSDITDEQYEEF
CCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHCCCCHHHHHHCCCCCCHHHHHHH
YRNIAYAIDKPWITIHNKSEGVIEFTNLLFIPSSKTFDLFHPDRKSRVKLYIKKVFITDE
HHHHHHHCCCCEEEEECCCCCEEEEEEEEEECCCCEEECCCCCCHHHHEEEEEEEEEECC
NVALIPKYMRFLRGVVDSEDLPLNISRETLQHSPLIDKIQASITKKVITELEKQKTKDQG
CCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
EYETFWNNFGAVLKEGLCEGTADVDKLLKICLFRSALQDKFISLDEYIANLKSEQKNIYY
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
ITGDDLEALKSSPQIEGLLSRNIDVLLLTDDVDKFWVMVTRKYNDYVLKSVTSANIEIDN
EECCCHHHHHCCCCHHHHHHCCCEEEEEECCCCEEEEEEEECCCHHHHHHHCCCCEEEEC
CDTKTAESSDTNNDAKDDTSSSDDKNCEQLIKYFKEVLGDKVKSVEVSKKLTRSPVCLTV
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEE
PEGSMDIRTERFLIEQKQLSSHSSKILEINPNHTIIKKINENIKLNQNLDVNKQLVMTLL
CCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCCEEECCCCCCHHHHHHHHH
DQSYLIEGQPIPDLQDYCNRINFFIEKSVN
CCHHEECCCCCCCHHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA