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The map label for this gene is rsh [H]

Identifier: 189183572

GI number: 189183572

Start: 694372

End: 694947

Strand: Reverse

Name: rsh [H]

Synonym: OTT_0665

Alternate gene names: 189183572

Gene position: 694947-694372 (Counterclockwise)

Preceding gene: 189183573

Following gene: 189183569

Centisome position: 34.59

GC content: 31.08

Gene sequence:

>576_bases
ATGATAGACTTTTATAGCGAAAGCTTACTAAATAAGCTGTTTGAAACCAACGTAAGATTTAATACTAAAATTGATCTTGA
TAAAGTTGAAAAAGCAATATTTTATGCCCAAAAATATCATGGTCAGCAAAAGAGAGATACAGGAGAACCTTATTATATGC
ATCCATTAGAAGTAGCTTATATGGTTGCAGACTACAGCTTTGAAACAGATACGATTATTACAGCAATACTACATGATACT
ATCGAAGACACAACACTAACCAAAGAAAAGATTGTTAAGGTATTCGGTAGAAAAATTGCGGAACAGGTTTCAGATCTCAC
CAGGATTAAGGATAATAAAAAAATCAGTTCTAGAGAGATGATTCAAACATTATATAACCGAAATAAAACAGAACTATTAT
TAATTAAGCTTTTCGACCGATTCCATAATATTCAGACTGTATCAATAAAACCTTATGAAAAAAGACAAGAAATCATACTA
GAAACTCAGCAAGAATTTATACCTCTTGCTAAGTACCTTAATCTACCAAAGATTGGAGAACTCTTAAGTGAATATTGCAA
ACTTAATGCTAGCTAG

Upstream 100 bases:

>100_bases
TCAAATTAATTCGCTTCTTTCACAGTTTTTATCTGAGATTGAAGTATATAAAAAGTTTAATTTATTGTATAATTTATTAA
AGATTATTTAGAGATGAAAA

Downstream 100 bases:

>100_bases
TATATGGTTTAACTAGTAAAATATTATCATTCGGATGTACAATTTGATATGTCCCCCATACAACAATCTTTAAATTGATC
AGGTGTATAAATACGAAGAT

Product: RelA/SpoT-related protein

Products: NA

Alternate protein names: (p)ppGpp synthase; ATP:GTP 3'-pyrophosphotransferase [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MIDFYSESLLNKLFETNVRFNTKIDLDKVEKAIFYAQKYHGQQKRDTGEPYYMHPLEVAYMVADYSFETDTIITAILHDT
IEDTTLTKEKIVKVFGRKIAEQVSDLTRIKDNKKISSREMIQTLYNRNKTELLLIKLFDRFHNIQTVSIKPYEKRQEIIL
ETQQEFIPLAKYLNLPKIGELLSEYCKLNAS

Sequences:

>Translated_191_residues
MIDFYSESLLNKLFETNVRFNTKIDLDKVEKAIFYAQKYHGQQKRDTGEPYYMHPLEVAYMVADYSFETDTIITAILHDT
IEDTTLTKEKIVKVFGRKIAEQVSDLTRIKDNKKISSREMIQTLYNRNKTELLLIKLFDRFHNIQTVSIKPYEKRQEIIL
ETQQEFIPLAKYLNLPKIGELLSEYCKLNAS
>Mature_191_residues
MIDFYSESLLNKLFETNVRFNTKIDLDKVEKAIFYAQKYHGQQKRDTGEPYYMHPLEVAYMVADYSFETDTIITAILHDT
IEDTTLTKEKIVKVFGRKIAEQVSDLTRIKDNKKISSREMIQTLYNRNKTELLLIKLFDRFHNIQTVSIKPYEKRQEIIL
ETQQEFIPLAKYLNLPKIGELLSEYCKLNAS

Specific function: Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. Plays a role in ada

COG id: COG0317

COG function: function code TK; Guanosine polyphosphate pyrophosphohydrolases/synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HD domain [H]

Homologues:

Organism=Escherichia coli, GI1790082, Length=184, Percent_Identity=33.1521739130435, Blast_Score=96, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI25143118, Length=129, Percent_Identity=30.2325581395349, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR012675
- InterPro:   IPR003607
- InterPro:   IPR007685
- InterPro:   IPR004811
- InterPro:   IPR004095
- InterPro:   IPR012676 [H]

Pfam domain/function: PF01842 ACT; PF04607 RelA_SpoT; PF02824 TGS [H]

EC number: =2.7.6.5 [H]

Molecular weight: Translated: 22557; Mature: 22557

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDFYSESLLNKLFETNVRFNTKIDLDKVEKAIFYAQKYHGQQKRDTGEPYYMHPLEVAY
CCCHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHCCCCCCCCCCCEEECHHHHHH
MVADYSFETDTIITAILHDTIEDTTLTKEKIVKVFGRKIAEQVSDLTRIKDNKKISSREM
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IQTLYNRNKTELLLIKLFDRFHNIQTVSIKPYEKRQEIILETQQEFIPLAKYLNLPKIGE
HHHHHCCCCHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LLSEYCKLNAS
HHHHHHCCCCC
>Mature Secondary Structure
MIDFYSESLLNKLFETNVRFNTKIDLDKVEKAIFYAQKYHGQQKRDTGEPYYMHPLEVAY
CCCHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHCCCCCCCCCCCEEECHHHHHH
MVADYSFETDTIITAILHDTIEDTTLTKEKIVKVFGRKIAEQVSDLTRIKDNKKISSREM
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IQTLYNRNKTELLLIKLFDRFHNIQTVSIKPYEKRQEIILETQQEFIPLAKYLNLPKIGE
HHHHHCCCCHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LLSEYCKLNAS
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA