Click here to switch to the map view.

The map label for this gene is tsf [H]

Identifier: 189183505

GI number: 189183505

Start: 615911

End: 616840

Strand: Reverse

Name: tsf [H]

Synonym: OTT_0598

Alternate gene names: 189183505

Gene position: 616840-615911 (Counterclockwise)

Preceding gene: 189183506

Following gene: 189183502

Centisome position: 30.7

GC content: 33.87

Gene sequence:

>930_bases
ATGAAAGAAAAAGAATTAGTGGTTAATACTAAAACTAATGGCTCTAAATCCGAAGATATAGTTATAAGTATTAGCCTAGT
TAAGAAGTTACGTGATGCTACTGGCGCTGCCATGACTAGCTGTAAGCAAGCATTGCAGGAGGCTAAAGGTGATATTGAAG
AAGCTATTAAAGTTTTACGTAAGACCAACTTAGCTCAAATGTCTTCAAAGTTACAACGTAAAGCTGACGAGGGAATAGTA
GCATTAGCTGTAGATAATAACAAAGGCGCAATTATAGAAATTAAGTTTGAAACAGATTTTGTTGCACGAAATGAAAGATT
GCAAAAATTAGCTACTGAAGCTGTTCAACTAGCTTTAGTTCATGATAATTTAACAGACTTAAAAAATGCTAAATTATCAT
CAGGCGAAACTCTTGAATCTCAAATAAGCCAAGATATTGCTGTTATAGGTGAAAATATACAAGTAAGCAGAATTAGACAA
GTTAAGCTAGTTGGCAATGGTATTATAGCATCATACATACATAATAGCGTAGCTCCAAATTTAGGCCAGATTGCTGTATT
AGTAGCTTTAGAAGGTAATGTTGAATCAGACAAGCTGGCAAAACTAGGAAAAAATATAGCAATGCATATTGCTGCTACTA
ATCCTAGGTTTTTAAGTTCAAATGAGGTACCAGAAAGTGTAATTATGCAAGAAAAGGAAATTTTTACTGCTCAAGCTCGT
GCTACTGGCAAACCAGAGAAAGTAATTGAAAAAATGATTGAGGGGCGAGTAAGTAAGTTTCTAGAAGAAACTGTATTGCT
AGAGCAAGCTTTTGTTATTGATGGTAAAACAAAAATTTCTGAAGTATTGAGTAATGCTGCTAAAGAACTTGGCAGTGAAA
TTAAGATTACTGGATTTTCTTGCTTAAAAGCTGGAGAAGTAGTTGAATAA

Upstream 100 bases:

>100_bases
AAGCTGCTAAAAAAATTACTAAAATGAAACCTAGTAAAAAGGTAACAAAAATAAATGTTGGACAAGATCAAAATAAATTA
GAAAAAGATAATAAAGATTT

Downstream 100 bases:

>100_bases
TAATAGGACTAAGAAATTTTATTTCTTAGTCCTTGCAAGAGTTAAAGCTTGTTATGTTAAATAGTAGAGAATACGACTTT
TAATAGCTAATGATCTCTCA

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MKEKELVVNTKTNGSKSEDIVISISLVKKLRDATGAAMTSCKQALQEAKGDIEEAIKVLRKTNLAQMSSKLQRKADEGIV
ALAVDNNKGAIIEIKFETDFVARNERLQKLATEAVQLALVHDNLTDLKNAKLSSGETLESQISQDIAVIGENIQVSRIRQ
VKLVGNGIIASYIHNSVAPNLGQIAVLVALEGNVESDKLAKLGKNIAMHIAATNPRFLSSNEVPESVIMQEKEIFTAQAR
ATGKPEKVIEKMIEGRVSKFLEETVLLEQAFVIDGKTKISEVLSNAAKELGSEIKITGFSCLKAGEVVE

Sequences:

>Translated_309_residues
MKEKELVVNTKTNGSKSEDIVISISLVKKLRDATGAAMTSCKQALQEAKGDIEEAIKVLRKTNLAQMSSKLQRKADEGIV
ALAVDNNKGAIIEIKFETDFVARNERLQKLATEAVQLALVHDNLTDLKNAKLSSGETLESQISQDIAVIGENIQVSRIRQ
VKLVGNGIIASYIHNSVAPNLGQIAVLVALEGNVESDKLAKLGKNIAMHIAATNPRFLSSNEVPESVIMQEKEIFTAQAR
ATGKPEKVIEKMIEGRVSKFLEETVLLEQAFVIDGKTKISEVLSNAAKELGSEIKITGFSCLKAGEVVE
>Mature_309_residues
MKEKELVVNTKTNGSKSEDIVISISLVKKLRDATGAAMTSCKQALQEAKGDIEEAIKVLRKTNLAQMSSKLQRKADEGIV
ALAVDNNKGAIIEIKFETDFVARNERLQKLATEAVQLALVHDNLTDLKNAKLSSGETLESQISQDIAVIGENIQVSRIRQ
VKLVGNGIIASYIHNSVAPNLGQIAVLVALEGNVESDKLAKLGKNIAMHIAATNPRFLSSNEVPESVIMQEKEIFTAQAR
ATGKPEKVIEKMIEGRVSKFLEETVLLEQAFVIDGKTKISEVLSNAAKELGSEIKITGFSCLKAGEVVE

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome [H]

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family [H]

Homologues:

Organism=Homo sapiens, GI171846268, Length=217, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1786366, Length=292, Percent_Identity=36.3013698630137, Blast_Score=156, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17561440, Length=297, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19921466, Length=304, Percent_Identity=25.6578947368421, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR009060
- InterPro:   IPR000449 [H]

Pfam domain/function: PF00889 EF_TS; PF00627 UBA [H]

EC number: NA

Molecular weight: Translated: 33490; Mature: 33490

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKELVVNTKTNGSKSEDIVISISLVKKLRDATGAAMTSCKQALQEAKGDIEEAIKVLR
CCCCCEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KTNLAQMSSKLQRKADEGIVALAVDNNKGAIIEIKFETDFVARNERLQKLATEAVQLALV
HCCHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
HDNLTDLKNAKLSSGETLESQISQDIAVIGENIQVSRIRQVKLVGNGIIASYIHNSVAPN
HCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHEEEEEECCCHHHHHHHHHCCCC
LGQIAVLVALEGNVESDKLAKLGKNIAMHIAATNPRFLSSNEVPESVIMQEKEIFTAQAR
CCCEEEEEEECCCCCHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
ATGKPEKVIEKMIEGRVSKFLEETVLLEQAFVIDGKTKISEVLSNAAKELGSEIKITGFS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHCCCCEEEECHH
CLKAGEVVE
HHCCCCCCC
>Mature Secondary Structure
MKEKELVVNTKTNGSKSEDIVISISLVKKLRDATGAAMTSCKQALQEAKGDIEEAIKVLR
CCCCCEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KTNLAQMSSKLQRKADEGIVALAVDNNKGAIIEIKFETDFVARNERLQKLATEAVQLALV
HCCHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
HDNLTDLKNAKLSSGETLESQISQDIAVIGENIQVSRIRQVKLVGNGIIASYIHNSVAPN
HCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHEEEEEECCCHHHHHHHHHCCCC
LGQIAVLVALEGNVESDKLAKLGKNIAMHIAATNPRFLSSNEVPESVIMQEKEIFTAQAR
CCCEEEEEEECCCCCHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
ATGKPEKVIEKMIEGRVSKFLEETVLLEQAFVIDGKTKISEVLSNAAKELGSEIKITGFS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHCCCCEEEECHH
CLKAGEVVE
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA