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The map label for this gene is ltrA [H]

Identifier: 189183268

GI number: 189183268

Start: 368844

End: 369377

Strand: Reverse

Name: ltrA [H]

Synonym: OTT_0361

Alternate gene names: 189183268

Gene position: 369377-368844 (Counterclockwise)

Preceding gene: 189183273

Following gene: 189183267

Centisome position: 18.39

GC content: 33.9

Gene sequence:

>534_bases
ATGGCTGTACACAGCATAGACAGAAATACATGGTTAACGAAACTTGAGCGTATAAAGTTGCTATCATCGAAAAATCAAGA
CATAAAGTTTAATAATCTTGGACATATTATCGATTTAAAGATGTTAGAAGAACAATATAAGGAACTCGATAGCAAGAAAG
CTATAGGAATAGATGGTATAACCAAAGAGGATTATGGTAAGAAATTGAAAGCAAATCTGCTCTCGCTTCTTACAAGAATT
CGCAAAGGGCAATATCAAGCTAAACCTGCACGAATAACGGAAATTCCAAAAGAAGATGGAGGCAAAAGACCTTTGGTAAT
ATCATGTTTTGAAGATAAGATAATCGAGTCTGCAGTAAGCAAGATACTAAACTCTGTGTTTGAGCCAATATTCTTAAAGT
ATTCATATGGATTTGGACCTAAGTTAAATGCACACGATGCTTTAAGGGAGTTAAATAGACTTACGTATAACTTCAATAAA
GGGGCTATAGTAGAGATTGATAACAAAGTGTTTCAATACAATCAAGCATTGTGA

Upstream 100 bases:

>100_bases
ATGGTGTAAGGATGGCTGAGTTAACCATAGTAGTGATGAAACCAAGTAATGTTGGTAGAGCGAAGGGTTAGCAGAAAAGT
AAGAATGCAAGAGGGAAACA

Downstream 100 bases:

>100_bases
GTTGATGGAATTTCTAAGAAAGAGAATATCTGACAAGAAATTTCTAAGACTAGTTATGAAACTGATTGAAACACCAATCA
TAGAAAATGATACTATAGTT

Product: reverse transcriptase

Products: NA

Alternate protein names: Reverse-transcriptase; RNA maturase; DNA endonuclease [H]

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MAVHSIDRNTWLTKLERIKLLSSKNQDIKFNNLGHIIDLKMLEEQYKELDSKKAIGIDGITKEDYGKKLKANLLSLLTRI
RKGQYQAKPARITEIPKEDGGKRPLVISCFEDKIIESAVSKILNSVFEPIFLKYSYGFGPKLNAHDALRELNRLTYNFNK
GAIVEIDNKVFQYNQAL

Sequences:

>Translated_177_residues
MAVHSIDRNTWLTKLERIKLLSSKNQDIKFNNLGHIIDLKMLEEQYKELDSKKAIGIDGITKEDYGKKLKANLLSLLTRI
RKGQYQAKPARITEIPKEDGGKRPLVISCFEDKIIESAVSKILNSVFEPIFLKYSYGFGPKLNAHDALRELNRLTYNFNK
GAIVEIDNKVFQYNQAL
>Mature_176_residues
AVHSIDRNTWLTKLERIKLLSSKNQDIKFNNLGHIIDLKMLEEQYKELDSKKAIGIDGITKEDYGKKLKANLLSLLTRIR
KGQYQAKPARITEIPKEDGGKRPLVISCFEDKIIESAVSKILNSVFEPIFLKYSYGFGPKLNAHDALRELNRLTYNFNKG
AIVEIDNKVFQYNQAL

Specific function: Multifunctional protein that promotes group II intron splicing and mobility by acting both on RNA and DNA. It has three activities:reverse transcriptase (RT) for intron duplication, maturase to promote splicing, and DNA endonuclease for site- specific cle

COG id: COG3344

COG function: function code L; Retron-type reverse transcriptase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 reverse transcriptase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003615
- InterPro:   IPR002866
- InterPro:   IPR000477 [H]

Pfam domain/function: PF01348 Intron_maturas2; PF00078 RVT_1 [H]

EC number: =2.7.7.49 [H]

Molecular weight: Translated: 20314; Mature: 20183

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVHSIDRNTWLTKLERIKLLSSKNQDIKFNNLGHIIDLKMLEEQYKELDSKKAIGIDGI
CCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
TKEDYGKKLKANLLSLLTRIRKGQYQAKPARITEIPKEDGGKRPLVISCFEDKIIESAVS
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCEEEEHHHHHHHHHHHH
KILNSVFEPIFLKYSYGFGPKLNAHDALRELNRLTYNFNKGAIVEIDNKVFQYNQAL
HHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHEEECCCCEEEEECCHHHHHCCCC
>Mature Secondary Structure 
AVHSIDRNTWLTKLERIKLLSSKNQDIKFNNLGHIIDLKMLEEQYKELDSKKAIGIDGI
CCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
TKEDYGKKLKANLLSLLTRIRKGQYQAKPARITEIPKEDGGKRPLVISCFEDKIIESAVS
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCEEEEHHHHHHHHHHHH
KILNSVFEPIFLKYSYGFGPKLNAHDALRELNRLTYNFNKGAIVEIDNKVFQYNQAL
HHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHEEECCCCEEEEECCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655550; 11157264; 10488339; 9353259; 10413481; 11731786 [H]